#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q09118 uniprotkb:P30409 intact:EBI-8104885|intact:MINT-232302 intact:EBI-8104924|intact:MINT-232314 psi-mi:hbegf_chlae(display_long)|uniprotkb:HBEGF(gene name)|psi-mi:HBEGF(display_short)|uniprotkb:DTR(gene name synonym)|uniprotkb:HEGFL(gene name synonym) psi-mi:cd9_chlae(display_long)|uniprotkb:CD9(gene name)|psi-mi:CD9(display_short)|uniprotkb:27 kDa diphtheria toxin receptor-associated protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Brooke et al. (2002) pubmed:11846885|mint:MINT-5215113 taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8104921|mint:MINT-13833 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR015497(Epidermal growth factor receptor ligand)|interpro:IPR000742(EGF-like, type 3)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0016021"(integral component of membrane)|mint:MINT-711638(identity) go:"GO:0005576"(extracellular region)|dip:DIP-181N|go:"GO:0005178"(integrin binding)|go:"GO:0007155"(cell adhesion)|go:"GO:0007338"(single fertilization)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0014905"(myoblast fusion involved in skeletal muscle regeneration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0035036"(sperm-egg recognition)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0005886"(plasma membrane)|go:"GO:0090331"(negative regulation of platelet aggregation)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|interpro:IPR042055|mint:MINT-711644(identity) - comment:mint|function:May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts and smooth muscle but not endothelial cells. It is able to bind EGF receptors with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor|comment:"Stoichiometry: 1.0" comment:mint|function:Involved in platelet activation and aggregation. Regulates paranodal junction formation. Required for gamete fusion. Involved in cell adhesion, cell motility and tumor metastasis|function:Expression of DRAP27 elevates the number of diphtheria toxin receptors on toxin-sensitive cells|comment:"Stoichiometry: 1.0" comment:mint taxid:-4(in vivo)|taxid:-4(in vivo) - 2002/10/25 2014/10/16 rogid:1uxwkRWX/tZNDkcfxBEnqWKabVQ9534 rogid:Ww66V5LmEAVUDmPVL/NoJL3Bizo9534 intact-crc:1728921E201C6370|rigid:xA409UxQF/NDtjFipbqcqZPI8IA false tag:?-?(MINT-711639) tag:?-?(MINT-711645) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)