#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9UJY5	uniprotkb:Q92673	intact:EBI-447141|uniprotkb:Q5TG07|uniprotkb:Q9BW94|uniprotkb:Q9UG00|uniprotkb:Q9UGW0|uniprotkb:Q9UGW1|uniprotkb:A8K3D3|uniprotkb:Q5R3N1|uniprotkb:Q6IC75|uniprotkb:B0QYR7|uniprotkb:Q86YA9|uniprotkb:Q8NCS6|ensembl:ENSP00000341344	intact:EBI-1171329|uniprotkb:Q92856|uniprotkb:B2RNX7|ensembl:ENSP00000260197	psi-mi:gga1_human(display_long)|uniprotkb:Golgi-localized, gamma ear-containing, ARF-binding protein 1(gene name synonym)|uniprotkb:Gamma-adaptin-related protein 1(gene name synonym)|uniprotkb:GGA1(gene name)|psi-mi:GGA1(display_short)	psi-mi:sorl_human(display_long)|uniprotkb:Sorting protein-related receptor containing LDLR class A repeats(gene name synonym)|uniprotkb:SorLA-1(gene name synonym)|uniprotkb:Low-density lipoprotein receptor relative with 11 ligand-binding repeats(gene name synonym)|uniprotkb:SORL1(gene name)|psi-mi:SORL1(display_short)|uniprotkb:C11orf32(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Jacobsen et al. (2002)	pubmed:11821067|mint:MINT-5215069	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8091965|mint:MINT-19062	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001560.1|refseq:NP_001166158.1|refseq:NP_001166159.1|refseq:NP_037497.1|refseq:XP_005261574.1|refseq:XP_011528424.1|refseq:XP_005261577.1|refseq:XP_006724292.1|refseq:XP_016884249.1|refseq:XP_016884250.1|refseq:XP_016884251.1|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:1901998"(toxin transport)|go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR038425|interpro:IPR041198|mint:Q9UJY5|rcsb pdb:1J2J|rcsb pdb:1JWF|rcsb pdb:1JWG|rcsb pdb:1NA8|rcsb pdb:1NAF|rcsb pdb:1NWM|rcsb pdb:1O3X|rcsb pdb:1OM9|rcsb pdb:1OXZ|rcsb pdb:1PY1|rcsb pdb:1UJJ|rcsb pdb:1UJK|rcsb pdb:1X79|rcsb pdb:2DWX|rcsb pdb:2DWY|rcsb pdb:3G2S|rcsb pdb:3G2T|rcsb pdb:3G2U|rcsb pdb:3G2V|rcsb pdb:3G2W|reactome:R-HSA-8854214|reactome:R-HSA-977225|ensembl:ENSG00000100083(gene)|ensembl:ENST00000343632(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008104"(protein localization)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|mint:MINT-710965(identity)	refseq:NP_003096.1|ensembl:ENSG00000137642(gene)|ensembl:ENST00000260197(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010897"(negative regulation of triglyceride catabolic process)|go:"GO:0014910"(regulation of smooth muscle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0038020"(insulin receptor recycling)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051604"(protein maturation)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0097356"(perinucleolar compartment)|go:"GO:1900168"(positive regulation of glial cell-derived neurotrophic factor production)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902771"(positive regulation of choline O-acetyltransferase activity)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|go:"GO:1902955"(positive regulation of early endosome to recycling endosome transport)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1902963"(negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1902997"(negative regulation of neurofibrillary tangle assembly)|go:"GO:1904179"(positive regulation of adipose tissue development)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006581(VPS10)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR023415|interpro:IPR031777|interpro:IPR031778|interpro:IPR036055|interpro:IPR036116|mint:Q92673|rcsb pdb:2DM4|rcsb pdb:3G2S|rcsb pdb:3G2T|rcsb pdb:3WSX|rcsb pdb:3WSY|rcsb pdb:3WSZ|reactome:R-HSA-977225|go:"GO:2001137"(positive regulation of endocytic recycling)|dip:DIP-41229N|mint:MINT-710959(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2002/02/15	2019/01/30	rogid:3n7Nia4JzMiDja0I7mUcyihFFBc9606	rogid:JoB0wm+nsEc1vhUsfcaOrc9YwMc9606	intact-crc:90A1B8400D41E4CD|rigid:ff4BZdT0x3yLHSZaqZcgNmB02FM	false	tag:?-?(MINT-710969)|binding-associated region:1-147(MINT-710966)	tag:?-?(MINT-710960)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q92673	uniprotkb:Q9UJY4	intact:EBI-1171329|uniprotkb:Q92856|uniprotkb:B2RNX7|ensembl:ENSP00000260197	intact:EBI-447646|uniprotkb:O14564|uniprotkb:Q9NYN2|uniprotkb:Q9UPS2|uniprotkb:D3DWF0|ensembl:ENSP00000311962	psi-mi:sorl_human(display_long)|uniprotkb:Sorting protein-related receptor containing LDLR class A repeats(gene name synonym)|uniprotkb:SorLA-1(gene name synonym)|uniprotkb:Low-density lipoprotein receptor relative with 11 ligand-binding repeats(gene name synonym)|uniprotkb:SORL1(gene name)|psi-mi:SORL1(display_short)|uniprotkb:C11orf32(gene name synonym)	psi-mi:gga2_human(display_long)|uniprotkb:Golgi-localized, gamma ear-containing, ARF-binding protein 2(gene name synonym)|uniprotkb:Gamma-adaptin-related protein 2(gene name synonym)|uniprotkb:VHS domain and ear domain of gamma-adaptin(gene name synonym)|uniprotkb:GGA2(gene name)|psi-mi:GGA2(display_short)|uniprotkb:KIAA1080(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Jacobsen et al. (2002)	pubmed:11821067|mint:MINT-5215069	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8092007|mint:MINT-18467	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003096.1|ensembl:ENSG00000137642(gene)|ensembl:ENST00000260197(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010897"(negative regulation of triglyceride catabolic process)|go:"GO:0014910"(regulation of smooth muscle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0038020"(insulin receptor recycling)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051604"(protein maturation)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0097356"(perinucleolar compartment)|go:"GO:1900168"(positive regulation of glial cell-derived neurotrophic factor production)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902771"(positive regulation of choline O-acetyltransferase activity)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|go:"GO:1902955"(positive regulation of early endosome to recycling endosome transport)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1902963"(negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1902997"(negative regulation of neurofibrillary tangle assembly)|go:"GO:1904179"(positive regulation of adipose tissue development)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006581(VPS10)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR023415|interpro:IPR031777|interpro:IPR031778|interpro:IPR036055|interpro:IPR036116|mint:Q92673|rcsb pdb:2DM4|rcsb pdb:3G2S|rcsb pdb:3G2T|rcsb pdb:3WSX|rcsb pdb:3WSY|rcsb pdb:3WSZ|reactome:R-HSA-977225|go:"GO:2001137"(positive regulation of endocytic recycling)|dip:DIP-41229N|mint:MINT-711003(identity)	refseq:NP_055859.1|dip:DIP-31601N|ensembl:ENSG00000103365(gene)|ensembl:ENST00000309859(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR038425|interpro:IPR041198|mint:Q9UJY4|rcsb pdb:1MHQ|reactome:R-HSA-8854214|reactome:R-HSA-977225|mint:MINT-711009(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2002/02/15	2019/01/30	rogid:JoB0wm+nsEc1vhUsfcaOrc9YwMc9606	rogid:VD3+z3TdZr7Ius0oloo8bnMhwjQ9606	intact-crc:8AAD8AAFED60838F|rigid:3DYrwL0mYiP2XbrkvzvnA8ieB54	false	tag:?-?(MINT-711004)	tag:?-?(MINT-711013)|binding-associated region:1-163(MINT-711010)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q92673	uniprotkb:Q9UJY4	intact:EBI-1171329|uniprotkb:Q92856|uniprotkb:B2RNX7|ensembl:ENSP00000260197	intact:EBI-447646|uniprotkb:O14564|uniprotkb:Q9NYN2|uniprotkb:Q9UPS2|uniprotkb:D3DWF0|ensembl:ENSP00000311962	psi-mi:sorl_human(display_long)|uniprotkb:Sorting protein-related receptor containing LDLR class A repeats(gene name synonym)|uniprotkb:SorLA-1(gene name synonym)|uniprotkb:Low-density lipoprotein receptor relative with 11 ligand-binding repeats(gene name synonym)|uniprotkb:SORL1(gene name)|psi-mi:SORL1(display_short)|uniprotkb:C11orf32(gene name synonym)	psi-mi:gga2_human(display_long)|uniprotkb:Golgi-localized, gamma ear-containing, ARF-binding protein 2(gene name synonym)|uniprotkb:Gamma-adaptin-related protein 2(gene name synonym)|uniprotkb:VHS domain and ear domain of gamma-adaptin(gene name synonym)|uniprotkb:GGA2(gene name)|psi-mi:GGA2(display_short)|uniprotkb:KIAA1080(gene name synonym)	psi-mi:"MI:0096"(pull down)	Jacobsen et al. (2002)	pubmed:11821067|mint:MINT-5215069	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8092060|mint:MINT-18468	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003096.1|ensembl:ENSG00000137642(gene)|ensembl:ENST00000260197(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010897"(negative regulation of triglyceride catabolic process)|go:"GO:0014910"(regulation of smooth muscle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0038020"(insulin receptor recycling)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051604"(protein maturation)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0097356"(perinucleolar compartment)|go:"GO:1900168"(positive regulation of glial cell-derived neurotrophic factor production)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902771"(positive regulation of choline O-acetyltransferase activity)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|go:"GO:1902955"(positive regulation of early endosome to recycling endosome transport)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1902963"(negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1902997"(negative regulation of neurofibrillary tangle assembly)|go:"GO:1904179"(positive regulation of adipose tissue development)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006581(VPS10)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR023415|interpro:IPR031777|interpro:IPR031778|interpro:IPR036055|interpro:IPR036116|mint:Q92673|rcsb pdb:2DM4|rcsb pdb:3G2S|rcsb pdb:3G2T|rcsb pdb:3WSX|rcsb pdb:3WSY|rcsb pdb:3WSZ|reactome:R-HSA-977225|go:"GO:2001137"(positive regulation of endocytic recycling)|dip:DIP-41229N|mint:MINT-710979(identity)	refseq:NP_055859.1|dip:DIP-31601N|ensembl:ENSG00000103365(gene)|ensembl:ENST00000309859(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR038425|interpro:IPR041198|mint:Q9UJY4|rcsb pdb:1MHQ|reactome:R-HSA-8854214|reactome:R-HSA-977225|mint:MINT-710982(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2002/02/15	2014/10/16	rogid:JoB0wm+nsEc1vhUsfcaOrc9YwMc9606	rogid:VD3+z3TdZr7Ius0oloo8bnMhwjQ9606	intact-crc:9B26D66A229C74BE|rigid:3DYrwL0mYiP2XbrkvzvnA8ieB54	false	-	binding-associated region:1-163(MINT-710983)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q92673	uniprotkb:Q9UJY5	intact:EBI-1171329|uniprotkb:Q92856|uniprotkb:B2RNX7|ensembl:ENSP00000260197	intact:EBI-447141|uniprotkb:Q5TG07|uniprotkb:Q9BW94|uniprotkb:Q9UG00|uniprotkb:Q9UGW0|uniprotkb:Q9UGW1|uniprotkb:A8K3D3|uniprotkb:Q5R3N1|uniprotkb:Q6IC75|uniprotkb:B0QYR7|uniprotkb:Q86YA9|uniprotkb:Q8NCS6|ensembl:ENSP00000341344	psi-mi:sorl_human(display_long)|uniprotkb:Sorting protein-related receptor containing LDLR class A repeats(gene name synonym)|uniprotkb:SorLA-1(gene name synonym)|uniprotkb:Low-density lipoprotein receptor relative with 11 ligand-binding repeats(gene name synonym)|uniprotkb:SORL1(gene name)|psi-mi:SORL1(display_short)|uniprotkb:C11orf32(gene name synonym)	psi-mi:gga1_human(display_long)|uniprotkb:Golgi-localized, gamma ear-containing, ARF-binding protein 1(gene name synonym)|uniprotkb:Gamma-adaptin-related protein 1(gene name synonym)|uniprotkb:GGA1(gene name)|psi-mi:GGA1(display_short)	psi-mi:"MI:0096"(pull down)	Jacobsen et al. (2002)	pubmed:11821067|mint:MINT-5215069	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8092077|mint:MINT-19063	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003096.1|ensembl:ENSG00000137642(gene)|ensembl:ENST00000260197(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010897"(negative regulation of triglyceride catabolic process)|go:"GO:0014910"(regulation of smooth muscle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0038020"(insulin receptor recycling)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051604"(protein maturation)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0097356"(perinucleolar compartment)|go:"GO:1900168"(positive regulation of glial cell-derived neurotrophic factor production)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902771"(positive regulation of choline O-acetyltransferase activity)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|go:"GO:1902955"(positive regulation of early endosome to recycling endosome transport)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1902963"(negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1902997"(negative regulation of neurofibrillary tangle assembly)|go:"GO:1904179"(positive regulation of adipose tissue development)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006581(VPS10)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR023415|interpro:IPR031777|interpro:IPR031778|interpro:IPR036055|interpro:IPR036116|mint:Q92673|rcsb pdb:2DM4|rcsb pdb:3G2S|rcsb pdb:3G2T|rcsb pdb:3WSX|rcsb pdb:3WSY|rcsb pdb:3WSZ|reactome:R-HSA-977225|go:"GO:2001137"(positive regulation of endocytic recycling)|dip:DIP-41229N|mint:MINT-710991(identity)	refseq:NP_001001560.1|refseq:NP_001166158.1|refseq:NP_001166159.1|refseq:NP_037497.1|refseq:XP_005261574.1|refseq:XP_011528424.1|refseq:XP_005261577.1|refseq:XP_006724292.1|refseq:XP_016884249.1|refseq:XP_016884250.1|refseq:XP_016884251.1|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:1901998"(toxin transport)|go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR038425|interpro:IPR041198|mint:Q9UJY5|rcsb pdb:1J2J|rcsb pdb:1JWF|rcsb pdb:1JWG|rcsb pdb:1NA8|rcsb pdb:1NAF|rcsb pdb:1NWM|rcsb pdb:1O3X|rcsb pdb:1OM9|rcsb pdb:1OXZ|rcsb pdb:1PY1|rcsb pdb:1UJJ|rcsb pdb:1UJK|rcsb pdb:1X79|rcsb pdb:2DWX|rcsb pdb:2DWY|rcsb pdb:3G2S|rcsb pdb:3G2T|rcsb pdb:3G2U|rcsb pdb:3G2V|rcsb pdb:3G2W|reactome:R-HSA-8854214|reactome:R-HSA-977225|ensembl:ENSG00000100083(gene)|ensembl:ENST00000343632(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008104"(protein localization)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|mint:MINT-710994(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2002/02/15	2014/10/16	rogid:JoB0wm+nsEc1vhUsfcaOrc9YwMc9606	rogid:3n7Nia4JzMiDja0I7mUcyihFFBc9606	intact-crc:C78212D60A1A5026|rigid:ff4BZdT0x3yLHSZaqZcgNmB02FM	false	-	binding-associated region:1-147(MINT-710995)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)