#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:G5EG62 uniprotkb:Q18688 intact:EBI-6675165|ensemblmetazoa:F30H5.1.1 intact:EBI-313329|ensemblmetazoa:C47E8.5.1|ensemblmetazoa:C47E8.5.2|ensemblmetazoa:C47E8.5.3|ensemblmetazoa:C47E8.5.4 psi-mi:g5eg62_caeel(display_long)|uniprotkb:unc-45(gene name)|psi-mi:unc-45(display_short)|uniprotkb:CELE_F30H5.1(orf name)|uniprotkb:F30H5.1(orf name) psi-mi:hsp90_caeel(display_long)|uniprotkb:daf-21(gene name)|psi-mi:daf-21(display_short)|uniprotkb:Abnormal dauer formation protein 21(gene name synonym)|uniprotkb:C47E8.5(orf name) psi-mi:"MI:0045"(experimental interaction detection) Barral et al. (2002) pubmed:11809970|mint:MINT-5215060 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8086780|mint:MINT-14369 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F30H5.1.1(transcript)|ensemblmetazoa:WBGene00006781(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR019734|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024660|refseq:NP_497205.1|rcsb pdb:4I2W|rcsb pdb:4I2Z|wormbase:F30H5.1|rcsb pdb:5MZU|rcsb pdb:6QDK|rcsb pdb:6QDL|rcsb pdb:6QDM|mint:MINT-710850(identity) refseq:NP_506626.1|wormbase:C47E8.5|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990634"(protein phosphatase 5 binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:4GQT|rcsb pdb:4I2Z|go:"GO:0042802"(identical protein binding)|ensemblmetazoa:C47E8.5.1(transcript)|ensemblmetazoa:C47E8.5.2(transcript)|ensemblmetazoa:C47E8.5.3(transcript)|ensemblmetazoa:C47E8.5.4(transcript)|ensemblmetazoa:WBGene00000915(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0040024"(dauer larval development)|reactome:R-CEL-5675482|dip:DIP-25037N|reactome:R-CEL-1474151|reactome:R-CEL-203615|reactome:R-CEL-3371497|reactome:R-CEL-3371511|reactome:R-CEL-3371571|reactome:R-CEL-5218920|reactome:R-CEL-6798695|reactome:R-CEL-8863795|reactome:R-CEL-8937144|reactome:R-CEL-8939211|reactome:R-CEL-9009391|reactome:R-CEL-3371568|reactome:R-CEL-9652282|mint:MINT-710857(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2002/04/23 2014/10/16 rogid:NhJ+U8cdOnnRydF1kNMUf7GOi606239 rogid:goxx/LuRQ1JdMht41DCZyulxDpg6239 intact-crc:26CFE4CCD7D91B2E|rigid:S06Dy9Jw4/j4kjuX8XvNzGgFroM false binding-associated region:1-114(MINT-710851) binding-associated region:691-702(MINT-710858) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G5EG62 uniprotkb:P02566 intact:EBI-6675165|ensemblmetazoa:F30H5.1.1 intact:EBI-329238|uniprotkb:O02244|ensemblmetazoa:F11C3.3.1|ensemblmetazoa:F11C3.3.2|ensemblmetazoa:F11C3.3.3 psi-mi:g5eg62_caeel(display_long)|uniprotkb:unc-45(gene name)|psi-mi:unc-45(display_short)|uniprotkb:CELE_F30H5.1(orf name)|uniprotkb:F30H5.1(orf name) psi-mi:myo4_caeel(display_long)|uniprotkb:unc-54(gene name)|psi-mi:unc-54(display_short)|uniprotkb:myo-4(gene name synonym)|uniprotkb:Myosin heavy chain B(gene name synonym)|uniprotkb:Uncoordinated protein 54(gene name synonym)|uniprotkb:F11C3.3(orf name) psi-mi:"MI:0096"(pull down) Barral et al. (2002) pubmed:11809970|mint:MINT-5215060 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8086829|mint:MINT-14786 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F30H5.1.1(transcript)|ensemblmetazoa:WBGene00006781(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR019734|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024660|refseq:NP_497205.1|rcsb pdb:4I2W|rcsb pdb:4I2Z|wormbase:F30H5.1|rcsb pdb:5MZU|rcsb pdb:6QDK|rcsb pdb:6QDL|rcsb pdb:6QDM|mint:MINT-710868(identity) refseq:NP_493596.1|wormbase:F11C3.3|dip:DIP-26548N|ensemblmetazoa:F11C3.3.1(transcript)|ensemblmetazoa:F11C3.3.2(transcript)|ensemblmetazoa:F11C3.3.3(transcript)|ensemblmetazoa:WBGene00006789(gene)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0018991"(oviposition)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031672"(A band)|go:"GO:0051015"(actin filament binding)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|rcsb pdb:6QDJ|go:"GO:0040011"(locomotion)|mint:MINT-710873(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2002/04/23 2014/10/16 rogid:NhJ+U8cdOnnRydF1kNMUf7GOi606239 rogid:3b8NY0RNiYO8jJI3dfdNoVXa69c6239 intact-crc:9C41AACF87D57849|rigid:RCiD2ElqfxVYgGQ9rkWU/jqWAvI false binding-associated region:104-960(MINT-710869) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G5EG62 uniprotkb:Q18688 intact:EBI-6675165|ensemblmetazoa:F30H5.1.1 intact:EBI-313329|ensemblmetazoa:C47E8.5.1|ensemblmetazoa:C47E8.5.2|ensemblmetazoa:C47E8.5.3|ensemblmetazoa:C47E8.5.4 psi-mi:g5eg62_caeel(display_long)|uniprotkb:unc-45(gene name)|psi-mi:unc-45(display_short)|uniprotkb:CELE_F30H5.1(orf name)|uniprotkb:F30H5.1(orf name) psi-mi:hsp90_caeel(display_long)|uniprotkb:daf-21(gene name)|psi-mi:daf-21(display_short)|uniprotkb:Abnormal dauer formation protein 21(gene name synonym)|uniprotkb:C47E8.5(orf name) psi-mi:"MI:0096"(pull down) Barral et al. (2002) pubmed:11809970|mint:MINT-5215060 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8086912|mint:MINT-14368 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F30H5.1.1(transcript)|ensemblmetazoa:WBGene00006781(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR019734|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024660|refseq:NP_497205.1|rcsb pdb:4I2W|rcsb pdb:4I2Z|wormbase:F30H5.1|rcsb pdb:5MZU|rcsb pdb:6QDK|rcsb pdb:6QDL|rcsb pdb:6QDM|mint:MINT-710886(identity) refseq:NP_506626.1|wormbase:C47E8.5|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990634"(protein phosphatase 5 binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:4GQT|rcsb pdb:4I2Z|go:"GO:0042802"(identical protein binding)|ensemblmetazoa:C47E8.5.1(transcript)|ensemblmetazoa:C47E8.5.2(transcript)|ensemblmetazoa:C47E8.5.3(transcript)|ensemblmetazoa:C47E8.5.4(transcript)|ensemblmetazoa:WBGene00000915(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0040024"(dauer larval development)|reactome:R-CEL-5675482|dip:DIP-25037N|reactome:R-CEL-1474151|reactome:R-CEL-203615|reactome:R-CEL-3371497|reactome:R-CEL-3371511|reactome:R-CEL-3371571|reactome:R-CEL-5218920|reactome:R-CEL-6798695|reactome:R-CEL-8863795|reactome:R-CEL-8937144|reactome:R-CEL-8939211|reactome:R-CEL-9009391|reactome:R-CEL-3371568|reactome:R-CEL-9652282|mint:MINT-710892(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2002/04/23 2014/10/16 rogid:NhJ+U8cdOnnRydF1kNMUf7GOi606239 rogid:goxx/LuRQ1JdMht41DCZyulxDpg6239 intact-crc:2EAE9F24F101B2F7|rigid:S06Dy9Jw4/j4kjuX8XvNzGgFroM false binding-associated region:1-114(MINT-710887) binding-associated region:691-702(MINT-710893) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02566 uniprotkb:Q18688 intact:EBI-329238|uniprotkb:O02244|ensemblmetazoa:F11C3.3.1|ensemblmetazoa:F11C3.3.2|ensemblmetazoa:F11C3.3.3 intact:EBI-313329|ensemblmetazoa:C47E8.5.1|ensemblmetazoa:C47E8.5.2|ensemblmetazoa:C47E8.5.3|ensemblmetazoa:C47E8.5.4 psi-mi:myo4_caeel(display_long)|uniprotkb:unc-54(gene name)|psi-mi:unc-54(display_short)|uniprotkb:myo-4(gene name synonym)|uniprotkb:Myosin heavy chain B(gene name synonym)|uniprotkb:Uncoordinated protein 54(gene name synonym)|uniprotkb:F11C3.3(orf name) psi-mi:hsp90_caeel(display_long)|uniprotkb:daf-21(gene name)|psi-mi:daf-21(display_short)|uniprotkb:Abnormal dauer formation protein 21(gene name synonym)|uniprotkb:C47E8.5(orf name) psi-mi:"MI:0096"(pull down) Barral et al. (2002) pubmed:11809970|mint:MINT-5215060 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8086901|mint:MINT-16502 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493596.1|wormbase:F11C3.3|dip:DIP-26548N|ensemblmetazoa:F11C3.3.1(transcript)|ensemblmetazoa:F11C3.3.2(transcript)|ensemblmetazoa:F11C3.3.3(transcript)|ensemblmetazoa:WBGene00006789(gene)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0018991"(oviposition)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031672"(A band)|go:"GO:0051015"(actin filament binding)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|rcsb pdb:6QDJ|go:"GO:0040011"(locomotion)|mint:MINT-710878(identity) refseq:NP_506626.1|wormbase:C47E8.5|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990634"(protein phosphatase 5 binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:4GQT|rcsb pdb:4I2Z|go:"GO:0042802"(identical protein binding)|ensemblmetazoa:C47E8.5.1(transcript)|ensemblmetazoa:C47E8.5.2(transcript)|ensemblmetazoa:C47E8.5.3(transcript)|ensemblmetazoa:C47E8.5.4(transcript)|ensemblmetazoa:WBGene00000915(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0040024"(dauer larval development)|reactome:R-CEL-5675482|dip:DIP-25037N|reactome:R-CEL-1474151|reactome:R-CEL-203615|reactome:R-CEL-3371497|reactome:R-CEL-3371511|reactome:R-CEL-3371571|reactome:R-CEL-5218920|reactome:R-CEL-6798695|reactome:R-CEL-8863795|reactome:R-CEL-8937144|reactome:R-CEL-8939211|reactome:R-CEL-9009391|reactome:R-CEL-3371568|reactome:R-CEL-9652282|mint:MINT-710881(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2002/04/23 2014/10/16 rogid:3b8NY0RNiYO8jJI3dfdNoVXa69c6239 rogid:goxx/LuRQ1JdMht41DCZyulxDpg6239 intact-crc:642844F5A092B359|rigid:vYL0EqyFfaYnVkui8mNB5Zqrnx0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)