#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P02489 uniprotkb:P43320 intact:EBI-6875961|ensembl:ENSP00000291554|intact:EBI-25838900|uniprotkb:A0A140G945|uniprotkb:E9PHE4|uniprotkb:Q53X53 intact:EBI-974082|ensembl:ENSP00000381273|ensembl:ENSP00000498905|uniprotkb:Q9UCM8 psi-mi:cryaa_human(display_long)|uniprotkb:CRYAA(gene name)|psi-mi:CRYAA(display_short)|uniprotkb:CRYA1(gene name synonym)|uniprotkb:HSPB4(gene name synonym)|uniprotkb:Heat shock protein beta-4(gene name synonym) psi-mi:crbb2_human(display_long)|uniprotkb:Beta-B2 crystallin(gene name synonym)|uniprotkb:Beta-crystallin Bp(gene name synonym)|uniprotkb:CRYBB2(gene name)|psi-mi:CRYBB2(display_short)|uniprotkb:CRYB2(gene name synonym)|uniprotkb:CRYB2A(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fu et al. (2002) pubmed:11700327|mint:MINT-5214764 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8034614|mint:MINT-14200 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001300979.1|ensembl:ENSG00000160202(gene)|ensembl:ENST00000291554(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050896"(response to stimulus)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR012274(Alpha-crystallin, subunit A)|mint:P02489|rcsb pdb:6T1R|refseq:NP_000385.1|dip:DIP-41265N|mint:MINT-594150(identity) ensembl:ENSG00000244752(gene)|ensembl:ENST00000398215(transcript)|ensembl:ENST00000651629(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0007601"(visual perception)|go:"GO:0042802"(identical protein binding)|go:"GO:0050896"(response to stimulus)|interpro:IPR001064(Beta and gamma crystallin)|interpro:IPR011024(Gamma-crystallin related)|interpro:IPR033058|mint:P43320|rcsb pdb:1YTQ|refseq:NP_000487.1|refseq:XP_011528202.1|refseq:XP_006724204.1|mint:MINT-594156(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:"Technique: CAT assay"|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-4(in vivo)|taxid:-4(in vivo) - 2002/09/06 2014/10/16 rogid:+d2016YcOZzaZpV57L9crFbTzEA9606 rogid:CXsf29udifdbWRxtboJe4mnZAgM9606 intact-crc:206F28F1BF52F57D|rigid:SNcsoFIpwwm6JoqEc3opVAhV8lY false tag:?-?(MINT-594151) tag:?-?(MINT-594157) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P07315 uniprotkb:P02511 intact:EBI-6875941|ensembl:ENSP00000282141|ensembl:ENSP00000496418|uniprotkb:Q53R50 intact:EBI-739060|uniprotkb:O43416|uniprotkb:B0YIX0|uniprotkb:Q9UC37|uniprotkb:Q9UC38|uniprotkb:Q9UC39|uniprotkb:Q9UC40|uniprotkb:Q9UC41|ensembl:ENSP00000227251|ensembl:ENSP00000433560|ensembl:ENSP00000434247|ensembl:ENSP00000435931|ensembl:ENSP00000436051|ensembl:ENSP00000436089|ensembl:ENSP00000437149|ensembl:ENSP00000483554|ensembl:ENSP00000498735|ensembl:ENSP00000499082 psi-mi:crgc_human(display_long)|uniprotkb:CRYGC(gene name)|psi-mi:CRYGC(display_short)|uniprotkb:CRYG3(gene name synonym)|uniprotkb:Gamma-C-crystallin(gene name synonym)|uniprotkb:Gamma-crystallin 2-1(gene name synonym)|uniprotkb:Gamma-crystallin 3(gene name synonym) psi-mi:cryab_human(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-27(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:Rosenthal fiber component(gene name synonym)|uniprotkb:Heat shock protein beta-5(gene name synonym)|uniprotkb:HSPB5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fu et al. (2002) pubmed:11700327|mint:MINT-5214764 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8034665|mint:MINT-14213 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011508964.1|ensembl:ENSG00000163254(gene)|ensembl:ENSG00000285011(gene)|ensembl:ENST00000282141(transcript)|ensembl:ENST00000646204(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007601"(visual perception)|interpro:IPR001064(Beta and gamma crystallin)|interpro:IPR011024(Gamma-crystallin related)|mint:P07315|rcsb pdb:1LFE|rcsb pdb:2NBR|refseq:NP_066269.1|mint:MINT-594271(identity) ensembl:ENSG00000109846(gene)|ensembl:ENST00000227251(transcript)|ensembl:ENST00000526180(transcript)|ensembl:ENST00000527899(transcript)|ensembl:ENST00000527950(transcript)|ensembl:ENST00000531198(transcript)|ensembl:ENST00000533475(transcript)|ensembl:ENST00000533879(transcript)|ensembl:ENST00000616970(transcript)|ensembl:ENST00000650687(transcript)|ensembl:ENST00000651164(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P02511|rcsb pdb:2KLR|rcsb pdb:2N0K|rcsb pdb:2WJ7|rcsb pdb:2Y1Y|rcsb pdb:2Y1Z|rcsb pdb:2YGD|rcsb pdb:3J07|rcsb pdb:2Y22|rcsb pdb:3L1G|rcsb pdb:3SGM|rcsb pdb:3SGN|rcsb pdb:3SGO|rcsb pdb:3SGP|rcsb pdb:3SGR|rcsb pdb:3SGS|rcsb pdb:4M5S|rcsb pdb:4M5T|rcsb pdb:5VVV|rcsb pdb:6BP9|reactome:R-HSA-3371571|refseq:NP_001876.1|refseq:XP_011540910.1|refseq:NP_001276736.1|refseq:NP_001276737.1|dip:DIP-35017N|mint:MINT-594277(identity) - comment:"Stoichiometry: 1.0" crc64:AE08BED46B7849CB|comment:"Stoichiometry: 1.0" comment:"Technique: CAT assay"|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-4(in vivo)|taxid:-4(in vivo) - 2002/09/06 2014/10/16 rogid:sTGY543Prp3u+F8JqIobyIUsYT09606 rogid:495Z42oQhkAUdADrAEOKIC5oICo9606 intact-crc:9C41F1D5C09D001C|rigid:vzyw7fhCsRs8gh1EJVVsESV6LoI false tag:?-?(MINT-594272) tag:?-?(MINT-594278) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P43320 uniprotkb:P07315 intact:EBI-974082|ensembl:ENSP00000381273|ensembl:ENSP00000498905|uniprotkb:Q9UCM8 intact:EBI-6875941|ensembl:ENSP00000282141|ensembl:ENSP00000496418|uniprotkb:Q53R50 psi-mi:crbb2_human(display_long)|uniprotkb:Beta-B2 crystallin(gene name synonym)|uniprotkb:Beta-crystallin Bp(gene name synonym)|uniprotkb:CRYBB2(gene name)|psi-mi:CRYBB2(display_short)|uniprotkb:CRYB2(gene name synonym)|uniprotkb:CRYB2A(gene name synonym) psi-mi:crgc_human(display_long)|uniprotkb:CRYGC(gene name)|psi-mi:CRYGC(display_short)|uniprotkb:CRYG3(gene name synonym)|uniprotkb:Gamma-C-crystallin(gene name synonym)|uniprotkb:Gamma-crystallin 2-1(gene name synonym)|uniprotkb:Gamma-crystallin 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fu et al. (2002) pubmed:11700327|mint:MINT-5214764 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8034648|mint:MINT-16209 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000244752(gene)|ensembl:ENST00000398215(transcript)|ensembl:ENST00000651629(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0007601"(visual perception)|go:"GO:0042802"(identical protein binding)|go:"GO:0050896"(response to stimulus)|interpro:IPR001064(Beta and gamma crystallin)|interpro:IPR011024(Gamma-crystallin related)|interpro:IPR033058|mint:P43320|rcsb pdb:1YTQ|refseq:NP_000487.1|refseq:XP_011528202.1|refseq:XP_006724204.1|mint:MINT-594171(identity) refseq:XP_011508964.1|ensembl:ENSG00000163254(gene)|ensembl:ENSG00000285011(gene)|ensembl:ENST00000282141(transcript)|ensembl:ENST00000646204(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007601"(visual perception)|interpro:IPR001064(Beta and gamma crystallin)|interpro:IPR011024(Gamma-crystallin related)|mint:P07315|rcsb pdb:1LFE|rcsb pdb:2NBR|refseq:NP_066269.1|mint:MINT-594165(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:"Technique: CAT assay"|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-4(in vivo)|taxid:-4(in vivo) - 2002/09/06 2014/10/16 rogid:CXsf29udifdbWRxtboJe4mnZAgM9606 rogid:sTGY543Prp3u+F8JqIobyIUsYT09606 intact-crc:0F56C1458841A7B9|rigid:H/4RvcBmdcO/ihs8qV3H2+ertAk false tag:?-?(MINT-594172) tag:?-?(MINT-594166) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P07315 uniprotkb:P02489 intact:EBI-6875941|ensembl:ENSP00000282141|ensembl:ENSP00000496418|uniprotkb:Q53R50 intact:EBI-6875961|ensembl:ENSP00000291554|intact:EBI-25838900|uniprotkb:A0A140G945|uniprotkb:E9PHE4|uniprotkb:Q53X53 psi-mi:crgc_human(display_long)|uniprotkb:CRYGC(gene name)|psi-mi:CRYGC(display_short)|uniprotkb:CRYG3(gene name synonym)|uniprotkb:Gamma-C-crystallin(gene name synonym)|uniprotkb:Gamma-crystallin 2-1(gene name synonym)|uniprotkb:Gamma-crystallin 3(gene name synonym) psi-mi:cryaa_human(display_long)|uniprotkb:CRYAA(gene name)|psi-mi:CRYAA(display_short)|uniprotkb:CRYA1(gene name synonym)|uniprotkb:HSPB4(gene name synonym)|uniprotkb:Heat shock protein beta-4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fu et al. (2002) pubmed:11700327|mint:MINT-5214764 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8034699|mint:MINT-14643 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011508964.1|ensembl:ENSG00000163254(gene)|ensembl:ENSG00000285011(gene)|ensembl:ENST00000282141(transcript)|ensembl:ENST00000646204(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007601"(visual perception)|interpro:IPR001064(Beta and gamma crystallin)|interpro:IPR011024(Gamma-crystallin related)|mint:P07315|rcsb pdb:1LFE|rcsb pdb:2NBR|refseq:NP_066269.1|mint:MINT-594383(identity) refseq:NP_001300979.1|ensembl:ENSG00000160202(gene)|ensembl:ENST00000291554(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050896"(response to stimulus)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR012274(Alpha-crystallin, subunit A)|mint:P02489|rcsb pdb:6T1R|refseq:NP_000385.1|dip:DIP-41265N|mint:MINT-594377(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:"Technique: CAT assay"|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-4(in vivo)|taxid:-4(in vivo) - 2002/09/06 2014/10/16 rogid:sTGY543Prp3u+F8JqIobyIUsYT09606 rogid:+d2016YcOZzaZpV57L9crFbTzEA9606 intact-crc:2C73087F2EE43155|rigid:ZYm6x+MhqRA/sP6gzntDpMaKxro false tag:?-?(MINT-594384) tag:?-?(MINT-594378) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P02511 uniprotkb:P43320 intact:EBI-739060|uniprotkb:O43416|uniprotkb:B0YIX0|uniprotkb:Q9UC37|uniprotkb:Q9UC38|uniprotkb:Q9UC39|uniprotkb:Q9UC40|uniprotkb:Q9UC41|ensembl:ENSP00000227251|ensembl:ENSP00000433560|ensembl:ENSP00000434247|ensembl:ENSP00000435931|ensembl:ENSP00000436051|ensembl:ENSP00000436089|ensembl:ENSP00000437149|ensembl:ENSP00000483554|ensembl:ENSP00000498735|ensembl:ENSP00000499082 intact:EBI-974082|ensembl:ENSP00000381273|ensembl:ENSP00000498905|uniprotkb:Q9UCM8 psi-mi:cryab_human(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-27(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:Rosenthal fiber component(gene name synonym)|uniprotkb:Heat shock protein beta-5(gene name synonym)|uniprotkb:HSPB5(gene name synonym) psi-mi:crbb2_human(display_long)|uniprotkb:Beta-B2 crystallin(gene name synonym)|uniprotkb:Beta-crystallin Bp(gene name synonym)|uniprotkb:CRYBB2(gene name)|psi-mi:CRYBB2(display_short)|uniprotkb:CRYB2(gene name synonym)|uniprotkb:CRYB2A(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fu et al. (2002) pubmed:11700327|mint:MINT-5214764 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8034682|mint:MINT-17764 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000109846(gene)|ensembl:ENST00000227251(transcript)|ensembl:ENST00000526180(transcript)|ensembl:ENST00000527899(transcript)|ensembl:ENST00000527950(transcript)|ensembl:ENST00000531198(transcript)|ensembl:ENST00000533475(transcript)|ensembl:ENST00000533879(transcript)|ensembl:ENST00000616970(transcript)|ensembl:ENST00000650687(transcript)|ensembl:ENST00000651164(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P02511|rcsb pdb:2KLR|rcsb pdb:2N0K|rcsb pdb:2WJ7|rcsb pdb:2Y1Y|rcsb pdb:2Y1Z|rcsb pdb:2YGD|rcsb pdb:3J07|rcsb pdb:2Y22|rcsb pdb:3L1G|rcsb pdb:3SGM|rcsb pdb:3SGN|rcsb pdb:3SGO|rcsb pdb:3SGP|rcsb pdb:3SGR|rcsb pdb:3SGS|rcsb pdb:4M5S|rcsb pdb:4M5T|rcsb pdb:5VVV|rcsb pdb:6BP9|reactome:R-HSA-3371571|refseq:NP_001876.1|refseq:XP_011540910.1|refseq:NP_001276736.1|refseq:NP_001276737.1|dip:DIP-35017N|mint:MINT-594292(identity) ensembl:ENSG00000244752(gene)|ensembl:ENST00000398215(transcript)|ensembl:ENST00000651629(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0007601"(visual perception)|go:"GO:0042802"(identical protein binding)|go:"GO:0050896"(response to stimulus)|interpro:IPR001064(Beta and gamma crystallin)|interpro:IPR011024(Gamma-crystallin related)|interpro:IPR033058|mint:P43320|rcsb pdb:1YTQ|refseq:NP_000487.1|refseq:XP_011528202.1|refseq:XP_006724204.1|mint:MINT-594286(identity) - crc64:AE08BED46B7849CB|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:"Technique: CAT assay"|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-4(in vivo)|taxid:-4(in vivo) - 2002/09/06 2014/10/16 rogid:495Z42oQhkAUdADrAEOKIC5oICo9606 rogid:CXsf29udifdbWRxtboJe4mnZAgM9606 intact-crc:ADB6F2F71FBEFFDD|rigid:uCiSsdOTJidL6Z4xTqVOXkV9Zg4 false tag:?-?(MINT-594293) tag:?-?(MINT-594287) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P43320 uniprotkb:P02489 intact:EBI-974082|ensembl:ENSP00000381273|ensembl:ENSP00000498905|uniprotkb:Q9UCM8 intact:EBI-6875961|ensembl:ENSP00000291554|intact:EBI-25838900|uniprotkb:A0A140G945|uniprotkb:E9PHE4|uniprotkb:Q53X53 psi-mi:crbb2_human(display_long)|uniprotkb:Beta-B2 crystallin(gene name synonym)|uniprotkb:Beta-crystallin Bp(gene name synonym)|uniprotkb:CRYBB2(gene name)|psi-mi:CRYBB2(display_short)|uniprotkb:CRYB2(gene name synonym)|uniprotkb:CRYB2A(gene name synonym) psi-mi:cryaa_human(display_long)|uniprotkb:CRYAA(gene name)|psi-mi:CRYAA(display_short)|uniprotkb:CRYA1(gene name synonym)|uniprotkb:HSPB4(gene name synonym)|uniprotkb:Heat shock protein beta-4(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Fu et al. (2002) pubmed:11700327|mint:MINT-5214764 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8034752|mint:MINT-14201 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000244752(gene)|ensembl:ENST00000398215(transcript)|ensembl:ENST00000651629(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0007601"(visual perception)|go:"GO:0042802"(identical protein binding)|go:"GO:0050896"(response to stimulus)|interpro:IPR001064(Beta and gamma crystallin)|interpro:IPR011024(Gamma-crystallin related)|interpro:IPR033058|mint:P43320|rcsb pdb:1YTQ|refseq:NP_000487.1|refseq:XP_011528202.1|refseq:XP_006724204.1|mint:MINT-594194(identity) refseq:NP_001300979.1|ensembl:ENSG00000160202(gene)|ensembl:ENST00000291554(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050896"(response to stimulus)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR012274(Alpha-crystallin, subunit A)|mint:P02489|rcsb pdb:6T1R|refseq:NP_000385.1|dip:DIP-41265N|mint:MINT-594191(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:"Technique: CAT assay"|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-4(in vivo)|taxid:-4(in vivo) - 2002/09/06 2014/10/16 rogid:CXsf29udifdbWRxtboJe4mnZAgM9606 rogid:+d2016YcOZzaZpV57L9crFbTzEA9606 intact-crc:F025FD37F9F4F3A9|rigid:SNcsoFIpwwm6JoqEc3opVAhV8lY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02511 uniprotkb:P07315 intact:EBI-739060|uniprotkb:O43416|uniprotkb:B0YIX0|uniprotkb:Q9UC37|uniprotkb:Q9UC38|uniprotkb:Q9UC39|uniprotkb:Q9UC40|uniprotkb:Q9UC41|ensembl:ENSP00000227251|ensembl:ENSP00000433560|ensembl:ENSP00000434247|ensembl:ENSP00000435931|ensembl:ENSP00000436051|ensembl:ENSP00000436089|ensembl:ENSP00000437149|ensembl:ENSP00000483554|ensembl:ENSP00000498735|ensembl:ENSP00000499082 intact:EBI-6875941|ensembl:ENSP00000282141|ensembl:ENSP00000496418|uniprotkb:Q53R50 psi-mi:cryab_human(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-27(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:Rosenthal fiber component(gene name synonym)|uniprotkb:Heat shock protein beta-5(gene name synonym)|uniprotkb:HSPB5(gene name synonym) psi-mi:crgc_human(display_long)|uniprotkb:CRYGC(gene name)|psi-mi:CRYGC(display_short)|uniprotkb:CRYG3(gene name synonym)|uniprotkb:Gamma-C-crystallin(gene name synonym)|uniprotkb:Gamma-crystallin 2-1(gene name synonym)|uniprotkb:Gamma-crystallin 3(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Fu et al. (2002) pubmed:11700327|mint:MINT-5214764 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8034763|mint:MINT-14212 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000109846(gene)|ensembl:ENST00000227251(transcript)|ensembl:ENST00000526180(transcript)|ensembl:ENST00000527899(transcript)|ensembl:ENST00000527950(transcript)|ensembl:ENST00000531198(transcript)|ensembl:ENST00000533475(transcript)|ensembl:ENST00000533879(transcript)|ensembl:ENST00000616970(transcript)|ensembl:ENST00000650687(transcript)|ensembl:ENST00000651164(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P02511|rcsb pdb:2KLR|rcsb pdb:2N0K|rcsb pdb:2WJ7|rcsb pdb:2Y1Y|rcsb pdb:2Y1Z|rcsb pdb:2YGD|rcsb pdb:3J07|rcsb pdb:2Y22|rcsb pdb:3L1G|rcsb pdb:3SGM|rcsb pdb:3SGN|rcsb pdb:3SGO|rcsb pdb:3SGP|rcsb pdb:3SGR|rcsb pdb:3SGS|rcsb pdb:4M5S|rcsb pdb:4M5T|rcsb pdb:5VVV|rcsb pdb:6BP9|reactome:R-HSA-3371571|refseq:NP_001876.1|refseq:XP_011540910.1|refseq:NP_001276736.1|refseq:NP_001276737.1|dip:DIP-35017N|mint:MINT-594213(identity) refseq:XP_011508964.1|ensembl:ENSG00000163254(gene)|ensembl:ENSG00000285011(gene)|ensembl:ENST00000282141(transcript)|ensembl:ENST00000646204(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007601"(visual perception)|interpro:IPR001064(Beta and gamma crystallin)|interpro:IPR011024(Gamma-crystallin related)|mint:P07315|rcsb pdb:1LFE|rcsb pdb:2NBR|refseq:NP_066269.1|mint:MINT-594210(identity) - crc64:AE08BED46B7849CB|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:"Technique: CAT assay"|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-4(in vivo)|taxid:-4(in vivo) - 2002/09/06 2014/10/16 rogid:495Z42oQhkAUdADrAEOKIC5oICo9606 rogid:sTGY543Prp3u+F8JqIobyIUsYT09606 intact-crc:1C95EF21B03B294C|rigid:vzyw7fhCsRs8gh1EJVVsESV6LoI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07315 uniprotkb:P43320 intact:EBI-6875941|ensembl:ENSP00000282141|ensembl:ENSP00000496418|uniprotkb:Q53R50 intact:EBI-974082|ensembl:ENSP00000381273|ensembl:ENSP00000498905|uniprotkb:Q9UCM8 psi-mi:crgc_human(display_long)|uniprotkb:CRYGC(gene name)|psi-mi:CRYGC(display_short)|uniprotkb:CRYG3(gene name synonym)|uniprotkb:Gamma-C-crystallin(gene name synonym)|uniprotkb:Gamma-crystallin 2-1(gene name synonym)|uniprotkb:Gamma-crystallin 3(gene name synonym) psi-mi:crbb2_human(display_long)|uniprotkb:Beta-B2 crystallin(gene name synonym)|uniprotkb:Beta-crystallin Bp(gene name synonym)|uniprotkb:CRYBB2(gene name)|psi-mi:CRYBB2(display_short)|uniprotkb:CRYB2(gene name synonym)|uniprotkb:CRYB2A(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Fu et al. (2002) pubmed:11700327|mint:MINT-5214764 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8034741|mint:MINT-16208 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011508964.1|ensembl:ENSG00000163254(gene)|ensembl:ENSG00000285011(gene)|ensembl:ENST00000282141(transcript)|ensembl:ENST00000646204(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007601"(visual perception)|interpro:IPR001064(Beta and gamma crystallin)|interpro:IPR011024(Gamma-crystallin related)|mint:P07315|rcsb pdb:1LFE|rcsb pdb:2NBR|refseq:NP_066269.1|mint:MINT-594182(identity) ensembl:ENSG00000244752(gene)|ensembl:ENST00000398215(transcript)|ensembl:ENST00000651629(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0007601"(visual perception)|go:"GO:0042802"(identical protein binding)|go:"GO:0050896"(response to stimulus)|interpro:IPR001064(Beta and gamma crystallin)|interpro:IPR011024(Gamma-crystallin related)|interpro:IPR033058|mint:P43320|rcsb pdb:1YTQ|refseq:NP_000487.1|refseq:XP_011528202.1|refseq:XP_006724204.1|mint:MINT-594185(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:"Technique: CAT assay"|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-4(in vivo)|taxid:-4(in vivo) - 2002/09/06 2014/10/16 rogid:sTGY543Prp3u+F8JqIobyIUsYT09606 rogid:CXsf29udifdbWRxtboJe4mnZAgM9606 intact-crc:023382A984EA1435|rigid:H/4RvcBmdcO/ihs8qV3H2+ertAk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02511 uniprotkb:P43320 intact:EBI-739060|uniprotkb:O43416|uniprotkb:B0YIX0|uniprotkb:Q9UC37|uniprotkb:Q9UC38|uniprotkb:Q9UC39|uniprotkb:Q9UC40|uniprotkb:Q9UC41|ensembl:ENSP00000227251|ensembl:ENSP00000433560|ensembl:ENSP00000434247|ensembl:ENSP00000435931|ensembl:ENSP00000436051|ensembl:ENSP00000436089|ensembl:ENSP00000437149|ensembl:ENSP00000483554|ensembl:ENSP00000498735|ensembl:ENSP00000499082 intact:EBI-974082|ensembl:ENSP00000381273|ensembl:ENSP00000498905|uniprotkb:Q9UCM8 psi-mi:cryab_human(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-27(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:Rosenthal fiber component(gene name synonym)|uniprotkb:Heat shock protein beta-5(gene name synonym)|uniprotkb:HSPB5(gene name synonym) psi-mi:crbb2_human(display_long)|uniprotkb:Beta-B2 crystallin(gene name synonym)|uniprotkb:Beta-crystallin Bp(gene name synonym)|uniprotkb:CRYBB2(gene name)|psi-mi:CRYBB2(display_short)|uniprotkb:CRYB2(gene name synonym)|uniprotkb:CRYB2A(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Fu et al. (2002) pubmed:11700327|mint:MINT-5214764 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8034785|mint:MINT-17763 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000109846(gene)|ensembl:ENST00000227251(transcript)|ensembl:ENST00000526180(transcript)|ensembl:ENST00000527899(transcript)|ensembl:ENST00000527950(transcript)|ensembl:ENST00000531198(transcript)|ensembl:ENST00000533475(transcript)|ensembl:ENST00000533879(transcript)|ensembl:ENST00000616970(transcript)|ensembl:ENST00000650687(transcript)|ensembl:ENST00000651164(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P02511|rcsb pdb:2KLR|rcsb pdb:2N0K|rcsb pdb:2WJ7|rcsb pdb:2Y1Y|rcsb pdb:2Y1Z|rcsb pdb:2YGD|rcsb pdb:3J07|rcsb pdb:2Y22|rcsb pdb:3L1G|rcsb pdb:3SGM|rcsb pdb:3SGN|rcsb pdb:3SGO|rcsb pdb:3SGP|rcsb pdb:3SGR|rcsb pdb:3SGS|rcsb pdb:4M5S|rcsb pdb:4M5T|rcsb pdb:5VVV|rcsb pdb:6BP9|reactome:R-HSA-3371571|refseq:NP_001876.1|refseq:XP_011540910.1|refseq:NP_001276736.1|refseq:NP_001276737.1|dip:DIP-35017N|mint:MINT-594231(identity) ensembl:ENSG00000244752(gene)|ensembl:ENST00000398215(transcript)|ensembl:ENST00000651629(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0007601"(visual perception)|go:"GO:0042802"(identical protein binding)|go:"GO:0050896"(response to stimulus)|interpro:IPR001064(Beta and gamma crystallin)|interpro:IPR011024(Gamma-crystallin related)|interpro:IPR033058|mint:P43320|rcsb pdb:1YTQ|refseq:NP_000487.1|refseq:XP_011528202.1|refseq:XP_006724204.1|mint:MINT-594228(identity) - crc64:AE08BED46B7849CB|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:"Technique: CAT assay"|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-4(in vivo)|taxid:-4(in vivo) - 2002/09/06 2014/10/16 rogid:495Z42oQhkAUdADrAEOKIC5oICo9606 rogid:CXsf29udifdbWRxtboJe4mnZAgM9606 intact-crc:3E2230DDBFF8893A|rigid:uCiSsdOTJidL6Z4xTqVOXkV9Zg4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02489 uniprotkb:P07315 intact:EBI-6875961|ensembl:ENSP00000291554|intact:EBI-25838900|uniprotkb:A0A140G945|uniprotkb:E9PHE4|uniprotkb:Q53X53 intact:EBI-6875941|ensembl:ENSP00000282141|ensembl:ENSP00000496418|uniprotkb:Q53R50 psi-mi:cryaa_human(display_long)|uniprotkb:CRYAA(gene name)|psi-mi:CRYAA(display_short)|uniprotkb:CRYA1(gene name synonym)|uniprotkb:HSPB4(gene name synonym)|uniprotkb:Heat shock protein beta-4(gene name synonym) psi-mi:crgc_human(display_long)|uniprotkb:CRYGC(gene name)|psi-mi:CRYGC(display_short)|uniprotkb:CRYG3(gene name synonym)|uniprotkb:Gamma-C-crystallin(gene name synonym)|uniprotkb:Gamma-crystallin 2-1(gene name synonym)|uniprotkb:Gamma-crystallin 3(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Fu et al. (2002) pubmed:11700327|mint:MINT-5214764 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8034796|mint:MINT-14642 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001300979.1|ensembl:ENSG00000160202(gene)|ensembl:ENST00000291554(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050896"(response to stimulus)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR012274(Alpha-crystallin, subunit A)|mint:P02489|rcsb pdb:6T1R|refseq:NP_000385.1|dip:DIP-41265N|mint:MINT-594245(identity) refseq:XP_011508964.1|ensembl:ENSG00000163254(gene)|ensembl:ENSG00000285011(gene)|ensembl:ENST00000282141(transcript)|ensembl:ENST00000646204(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007601"(visual perception)|interpro:IPR001064(Beta and gamma crystallin)|interpro:IPR011024(Gamma-crystallin related)|mint:P07315|rcsb pdb:1LFE|rcsb pdb:2NBR|refseq:NP_066269.1|mint:MINT-594248(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:"Technique: CAT assay"|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-4(in vivo)|taxid:-4(in vivo) - 2002/09/06 2014/10/16 rogid:+d2016YcOZzaZpV57L9crFbTzEA9606 rogid:sTGY543Prp3u+F8JqIobyIUsYT09606 intact-crc:D29222CBF63753DF|rigid:ZYm6x+MhqRA/sP6gzntDpMaKxro false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02511 uniprotkb:P02489 intact:EBI-739060|uniprotkb:O43416|uniprotkb:B0YIX0|uniprotkb:Q9UC37|uniprotkb:Q9UC38|uniprotkb:Q9UC39|uniprotkb:Q9UC40|uniprotkb:Q9UC41|ensembl:ENSP00000227251|ensembl:ENSP00000433560|ensembl:ENSP00000434247|ensembl:ENSP00000435931|ensembl:ENSP00000436051|ensembl:ENSP00000436089|ensembl:ENSP00000437149|ensembl:ENSP00000483554|ensembl:ENSP00000498735|ensembl:ENSP00000499082 intact:EBI-6875961|ensembl:ENSP00000291554|intact:EBI-25838900|uniprotkb:A0A140G945|uniprotkb:E9PHE4|uniprotkb:Q53X53 psi-mi:cryab_human(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-27(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:Rosenthal fiber component(gene name synonym)|uniprotkb:Heat shock protein beta-5(gene name synonym)|uniprotkb:HSPB5(gene name synonym) psi-mi:cryaa_human(display_long)|uniprotkb:CRYAA(gene name)|psi-mi:CRYAA(display_short)|uniprotkb:CRYA1(gene name synonym)|uniprotkb:HSPB4(gene name synonym)|uniprotkb:Heat shock protein beta-4(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Fu et al. (2002) pubmed:11700327|mint:MINT-5214764 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8034774|mint:MINT-17438 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000109846(gene)|ensembl:ENST00000227251(transcript)|ensembl:ENST00000526180(transcript)|ensembl:ENST00000527899(transcript)|ensembl:ENST00000527950(transcript)|ensembl:ENST00000531198(transcript)|ensembl:ENST00000533475(transcript)|ensembl:ENST00000533879(transcript)|ensembl:ENST00000616970(transcript)|ensembl:ENST00000650687(transcript)|ensembl:ENST00000651164(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P02511|rcsb pdb:2KLR|rcsb pdb:2N0K|rcsb pdb:2WJ7|rcsb pdb:2Y1Y|rcsb pdb:2Y1Z|rcsb pdb:2YGD|rcsb pdb:3J07|rcsb pdb:2Y22|rcsb pdb:3L1G|rcsb pdb:3SGM|rcsb pdb:3SGN|rcsb pdb:3SGO|rcsb pdb:3SGP|rcsb pdb:3SGR|rcsb pdb:3SGS|rcsb pdb:4M5S|rcsb pdb:4M5T|rcsb pdb:5VVV|rcsb pdb:6BP9|reactome:R-HSA-3371571|refseq:NP_001876.1|refseq:XP_011540910.1|refseq:NP_001276736.1|refseq:NP_001276737.1|dip:DIP-35017N|mint:MINT-594222(identity) refseq:NP_001300979.1|ensembl:ENSG00000160202(gene)|ensembl:ENST00000291554(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050896"(response to stimulus)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR012274(Alpha-crystallin, subunit A)|mint:P02489|rcsb pdb:6T1R|refseq:NP_000385.1|dip:DIP-41265N|mint:MINT-594219(identity) - crc64:AE08BED46B7849CB|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:"Technique: CAT assay"|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-4(in vivo)|taxid:-4(in vivo) - 2002/09/06 2014/10/16 rogid:495Z42oQhkAUdADrAEOKIC5oICo9606 rogid:+d2016YcOZzaZpV57L9crFbTzEA9606 intact-crc:44CF71FD38B81D66|rigid:eoEnEMVeStMxBOplzJofsa8Ar1k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43320 uniprotkb:P04792 intact:EBI-974082|ensembl:ENSP00000381273|ensembl:ENSP00000498905|uniprotkb:Q9UCM8 intact:EBI-352682|uniprotkb:Q6FI47|uniprotkb:Q96C20|uniprotkb:Q96EI7|uniprotkb:Q9UC34|uniprotkb:Q9UC35|uniprotkb:Q9UC36|uniprotkb:Q9UC31|ensembl:ENSP00000248553|uniprotkb:B2R4N8 psi-mi:crbb2_human(display_long)|uniprotkb:Beta-B2 crystallin(gene name synonym)|uniprotkb:Beta-crystallin Bp(gene name synonym)|uniprotkb:CRYBB2(gene name)|psi-mi:CRYBB2(display_short)|uniprotkb:CRYB2(gene name synonym)|uniprotkb:CRYB2A(gene name synonym) psi-mi:hspb1_human(display_long)|uniprotkb:HSPB1(gene name)|psi-mi:HSPB1(display_short)|uniprotkb:HSP27(gene name synonym)|uniprotkb:HSP28(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Stress-responsive protein 27(gene name synonym)|uniprotkb:Estrogen-regulated 24 kDa protein(gene name synonym)|uniprotkb:28 kDa heat shock protein(gene name synonym) psi-mi:"MI:0096"(pull down) Fu et al. (2002) pubmed:11700327|mint:MINT-5214764 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8034815|mint:MINT-16469 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000244752(gene)|ensembl:ENST00000398215(transcript)|ensembl:ENST00000651629(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0007601"(visual perception)|go:"GO:0042802"(identical protein binding)|go:"GO:0050896"(response to stimulus)|interpro:IPR001064(Beta and gamma crystallin)|interpro:IPR011024(Gamma-crystallin related)|interpro:IPR033058|mint:P43320|rcsb pdb:1YTQ|refseq:NP_000487.1|refseq:XP_011528202.1|refseq:XP_006724204.1|mint:MINT-594205(identity) refseq:NP_001531.1|ensembl:ENSG00000106211(gene)|ensembl:ENST00000248553(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P04792|rcsb pdb:2N3J|rcsb pdb:3Q9P|rcsb pdb:3Q9Q|rcsb pdb:4MJH|rcsb pdb:6DV5|rcsb pdb:6GJH|reactome:R-HSA-4420097|reactome:R-HSA-450408|reactome:R-HSA-5687128|reactome:R-HSA-9009391|dip:DIP-412N|mint:MINT-594202(identity) - comment:"Stoichiometry: 1.0" crc64:1B4DC44A6F6606D5|comment:"Stoichiometry: 1.0" comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2002/09/06 2014/10/16 rogid:CXsf29udifdbWRxtboJe4mnZAgM9606 rogid:vrDXIdzP30aHSDLHOh2D4x54eJY9606 intact-crc:F2560B7355B54794|rigid:OWY/6Vlv9TbmznKwDnnY8gbEqGA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04792 uniprotkb:P02489 intact:EBI-352682|uniprotkb:Q6FI47|uniprotkb:Q96C20|uniprotkb:Q96EI7|uniprotkb:Q9UC34|uniprotkb:Q9UC35|uniprotkb:Q9UC36|uniprotkb:Q9UC31|ensembl:ENSP00000248553|uniprotkb:B2R4N8 intact:EBI-6875961|ensembl:ENSP00000291554|intact:EBI-25838900|uniprotkb:A0A140G945|uniprotkb:E9PHE4|uniprotkb:Q53X53 psi-mi:hspb1_human(display_long)|uniprotkb:HSPB1(gene name)|psi-mi:HSPB1(display_short)|uniprotkb:HSP27(gene name synonym)|uniprotkb:HSP28(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Stress-responsive protein 27(gene name synonym)|uniprotkb:Estrogen-regulated 24 kDa protein(gene name synonym)|uniprotkb:28 kDa heat shock protein(gene name synonym) psi-mi:cryaa_human(display_long)|uniprotkb:CRYAA(gene name)|psi-mi:CRYAA(display_short)|uniprotkb:CRYA1(gene name synonym)|uniprotkb:HSPB4(gene name synonym)|uniprotkb:Heat shock protein beta-4(gene name synonym) psi-mi:"MI:0096"(pull down) Fu et al. (2002) pubmed:11700327|mint:MINT-5214764 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8034837|mint:MINT-16434 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001531.1|ensembl:ENSG00000106211(gene)|ensembl:ENST00000248553(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P04792|rcsb pdb:2N3J|rcsb pdb:3Q9P|rcsb pdb:3Q9Q|rcsb pdb:4MJH|rcsb pdb:6DV5|rcsb pdb:6GJH|reactome:R-HSA-4420097|reactome:R-HSA-450408|reactome:R-HSA-5687128|reactome:R-HSA-9009391|dip:DIP-412N|mint:MINT-594301(identity) refseq:NP_001300979.1|ensembl:ENSG00000160202(gene)|ensembl:ENST00000291554(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050896"(response to stimulus)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR012274(Alpha-crystallin, subunit A)|mint:P02489|rcsb pdb:6T1R|refseq:NP_000385.1|dip:DIP-41265N|mint:MINT-594304(identity) - crc64:1B4DC44A6F6606D5|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2002/09/06 2014/10/16 rogid:vrDXIdzP30aHSDLHOh2D4x54eJY9606 rogid:+d2016YcOZzaZpV57L9crFbTzEA9606 intact-crc:4C3D133267A06EBA|rigid:q9oVo6wsyeJXzSVkrR9GKRZSJUo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02511 uniprotkb:P04792 intact:EBI-739060|uniprotkb:O43416|uniprotkb:B0YIX0|uniprotkb:Q9UC37|uniprotkb:Q9UC38|uniprotkb:Q9UC39|uniprotkb:Q9UC40|uniprotkb:Q9UC41|ensembl:ENSP00000227251|ensembl:ENSP00000433560|ensembl:ENSP00000434247|ensembl:ENSP00000435931|ensembl:ENSP00000436051|ensembl:ENSP00000436089|ensembl:ENSP00000437149|ensembl:ENSP00000483554|ensembl:ENSP00000498735|ensembl:ENSP00000499082 intact:EBI-352682|uniprotkb:Q6FI47|uniprotkb:Q96C20|uniprotkb:Q96EI7|uniprotkb:Q9UC34|uniprotkb:Q9UC35|uniprotkb:Q9UC36|uniprotkb:Q9UC31|ensembl:ENSP00000248553|uniprotkb:B2R4N8 psi-mi:cryab_human(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-27(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:Rosenthal fiber component(gene name synonym)|uniprotkb:Heat shock protein beta-5(gene name synonym)|uniprotkb:HSPB5(gene name synonym) psi-mi:hspb1_human(display_long)|uniprotkb:HSPB1(gene name)|psi-mi:HSPB1(display_short)|uniprotkb:HSP27(gene name synonym)|uniprotkb:HSP28(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Stress-responsive protein 27(gene name synonym)|uniprotkb:Estrogen-regulated 24 kDa protein(gene name synonym)|uniprotkb:28 kDa heat shock protein(gene name synonym) psi-mi:"MI:0096"(pull down) Fu et al. (2002) pubmed:11700327|mint:MINT-5214764 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8034826|mint:MINT-17168 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000109846(gene)|ensembl:ENST00000227251(transcript)|ensembl:ENST00000526180(transcript)|ensembl:ENST00000527899(transcript)|ensembl:ENST00000527950(transcript)|ensembl:ENST00000531198(transcript)|ensembl:ENST00000533475(transcript)|ensembl:ENST00000533879(transcript)|ensembl:ENST00000616970(transcript)|ensembl:ENST00000650687(transcript)|ensembl:ENST00000651164(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P02511|rcsb pdb:2KLR|rcsb pdb:2N0K|rcsb pdb:2WJ7|rcsb pdb:2Y1Y|rcsb pdb:2Y1Z|rcsb pdb:2YGD|rcsb pdb:3J07|rcsb pdb:2Y22|rcsb pdb:3L1G|rcsb pdb:3SGM|rcsb pdb:3SGN|rcsb pdb:3SGO|rcsb pdb:3SGP|rcsb pdb:3SGR|rcsb pdb:3SGS|rcsb pdb:4M5S|rcsb pdb:4M5T|rcsb pdb:5VVV|rcsb pdb:6BP9|reactome:R-HSA-3371571|refseq:NP_001876.1|refseq:XP_011540910.1|refseq:NP_001276736.1|refseq:NP_001276737.1|dip:DIP-35017N|mint:MINT-594240(identity) refseq:NP_001531.1|ensembl:ENSG00000106211(gene)|ensembl:ENST00000248553(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P04792|rcsb pdb:2N3J|rcsb pdb:3Q9P|rcsb pdb:3Q9Q|rcsb pdb:4MJH|rcsb pdb:6DV5|rcsb pdb:6GJH|reactome:R-HSA-4420097|reactome:R-HSA-450408|reactome:R-HSA-5687128|reactome:R-HSA-9009391|dip:DIP-412N|mint:MINT-594237(identity) - crc64:AE08BED46B7849CB|comment:"Stoichiometry: 1.0" crc64:1B4DC44A6F6606D5|comment:"Stoichiometry: 1.0" comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2002/09/06 2014/10/16 rogid:495Z42oQhkAUdADrAEOKIC5oICo9606 rogid:vrDXIdzP30aHSDLHOh2D4x54eJY9606 intact-crc:6D3B497B654EF628|rigid:HlIost5vRGNZhOzHD7XSsVsRheE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02489 uniprotkb:P02511 intact:EBI-6875961|ensembl:ENSP00000291554|intact:EBI-25838900|uniprotkb:A0A140G945|uniprotkb:E9PHE4|uniprotkb:Q53X53 intact:EBI-739060|uniprotkb:O43416|uniprotkb:B0YIX0|uniprotkb:Q9UC37|uniprotkb:Q9UC38|uniprotkb:Q9UC39|uniprotkb:Q9UC40|uniprotkb:Q9UC41|ensembl:ENSP00000227251|ensembl:ENSP00000433560|ensembl:ENSP00000434247|ensembl:ENSP00000435931|ensembl:ENSP00000436051|ensembl:ENSP00000436089|ensembl:ENSP00000437149|ensembl:ENSP00000483554|ensembl:ENSP00000498735|ensembl:ENSP00000499082 psi-mi:cryaa_human(display_long)|uniprotkb:CRYAA(gene name)|psi-mi:CRYAA(display_short)|uniprotkb:CRYA1(gene name synonym)|uniprotkb:HSPB4(gene name synonym)|uniprotkb:Heat shock protein beta-4(gene name synonym) psi-mi:cryab_human(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-27(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:Rosenthal fiber component(gene name synonym)|uniprotkb:Heat shock protein beta-5(gene name synonym)|uniprotkb:HSPB5(gene name synonym) psi-mi:"MI:0011"(beta lactamase complementation) Fu et al. (2002) pubmed:11700327|mint:MINT-5214764 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8034873|mint:MINT-17439 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001300979.1|ensembl:ENSG00000160202(gene)|ensembl:ENST00000291554(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050896"(response to stimulus)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR012274(Alpha-crystallin, subunit A)|mint:P02489|rcsb pdb:6T1R|refseq:NP_000385.1|dip:DIP-41265N|mint:MINT-594256(identity) ensembl:ENSG00000109846(gene)|ensembl:ENST00000227251(transcript)|ensembl:ENST00000526180(transcript)|ensembl:ENST00000527899(transcript)|ensembl:ENST00000527950(transcript)|ensembl:ENST00000531198(transcript)|ensembl:ENST00000533475(transcript)|ensembl:ENST00000533879(transcript)|ensembl:ENST00000616970(transcript)|ensembl:ENST00000650687(transcript)|ensembl:ENST00000651164(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P02511|rcsb pdb:2KLR|rcsb pdb:2N0K|rcsb pdb:2WJ7|rcsb pdb:2Y1Y|rcsb pdb:2Y1Z|rcsb pdb:2YGD|rcsb pdb:3J07|rcsb pdb:2Y22|rcsb pdb:3L1G|rcsb pdb:3SGM|rcsb pdb:3SGN|rcsb pdb:3SGO|rcsb pdb:3SGP|rcsb pdb:3SGR|rcsb pdb:3SGS|rcsb pdb:4M5S|rcsb pdb:4M5T|rcsb pdb:5VVV|rcsb pdb:6BP9|reactome:R-HSA-3371571|refseq:NP_001876.1|refseq:XP_011540910.1|refseq:NP_001276736.1|refseq:NP_001276737.1|dip:DIP-35017N|mint:MINT-594262(identity) - comment:"Stoichiometry: 1.0" crc64:AE08BED46B7849CB|comment:"Stoichiometry: 1.0" comment:"Technique: CAT assay"|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-4(in vivo)|taxid:-4(in vivo) - 2002/09/06 2014/10/16 rogid:+d2016YcOZzaZpV57L9crFbTzEA9606 rogid:495Z42oQhkAUdADrAEOKIC5oICo9606 intact-crc:8987EA024F9FDF95|rigid:eoEnEMVeStMxBOplzJofsa8Ar1k false tag:?-?(MINT-594257) tag:?-?(MINT-594263) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P07315 uniprotkb:P02511 intact:EBI-6875941|ensembl:ENSP00000282141|ensembl:ENSP00000496418|uniprotkb:Q53R50 intact:EBI-739060|uniprotkb:O43416|uniprotkb:B0YIX0|uniprotkb:Q9UC37|uniprotkb:Q9UC38|uniprotkb:Q9UC39|uniprotkb:Q9UC40|uniprotkb:Q9UC41|ensembl:ENSP00000227251|ensembl:ENSP00000433560|ensembl:ENSP00000434247|ensembl:ENSP00000435931|ensembl:ENSP00000436051|ensembl:ENSP00000436089|ensembl:ENSP00000437149|ensembl:ENSP00000483554|ensembl:ENSP00000498735|ensembl:ENSP00000499082 psi-mi:crgc_human(display_long)|uniprotkb:CRYGC(gene name)|psi-mi:CRYGC(display_short)|uniprotkb:CRYG3(gene name synonym)|uniprotkb:Gamma-C-crystallin(gene name synonym)|uniprotkb:Gamma-crystallin 2-1(gene name synonym)|uniprotkb:Gamma-crystallin 3(gene name synonym) psi-mi:cryab_human(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-27(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:Rosenthal fiber component(gene name synonym)|uniprotkb:Heat shock protein beta-5(gene name synonym)|uniprotkb:HSPB5(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) Fu et al. (2002) pubmed:11700327|mint:MINT-5214764 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8034931|mint:MINT-14211 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011508964.1|ensembl:ENSG00000163254(gene)|ensembl:ENSG00000285011(gene)|ensembl:ENST00000282141(transcript)|ensembl:ENST00000646204(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007601"(visual perception)|interpro:IPR001064(Beta and gamma crystallin)|interpro:IPR011024(Gamma-crystallin related)|mint:P07315|rcsb pdb:1LFE|rcsb pdb:2NBR|refseq:NP_066269.1|mint:MINT-594344(identity) ensembl:ENSG00000109846(gene)|ensembl:ENST00000227251(transcript)|ensembl:ENST00000526180(transcript)|ensembl:ENST00000527899(transcript)|ensembl:ENST00000527950(transcript)|ensembl:ENST00000531198(transcript)|ensembl:ENST00000533475(transcript)|ensembl:ENST00000533879(transcript)|ensembl:ENST00000616970(transcript)|ensembl:ENST00000650687(transcript)|ensembl:ENST00000651164(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P02511|rcsb pdb:2KLR|rcsb pdb:2N0K|rcsb pdb:2WJ7|rcsb pdb:2Y1Y|rcsb pdb:2Y1Z|rcsb pdb:2YGD|rcsb pdb:3J07|rcsb pdb:2Y22|rcsb pdb:3L1G|rcsb pdb:3SGM|rcsb pdb:3SGN|rcsb pdb:3SGO|rcsb pdb:3SGP|rcsb pdb:3SGR|rcsb pdb:3SGS|rcsb pdb:4M5S|rcsb pdb:4M5T|rcsb pdb:5VVV|rcsb pdb:6BP9|reactome:R-HSA-3371571|refseq:NP_001876.1|refseq:XP_011540910.1|refseq:NP_001276736.1|refseq:NP_001276737.1|dip:DIP-35017N|mint:MINT-594348(identity) - comment:"Stoichiometry: 1.0" crc64:AE08BED46B7849CB|comment:"Stoichiometry: 1.0" comment:"Technique: CAT assay"|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2002/09/06 2014/10/16 rogid:sTGY543Prp3u+F8JqIobyIUsYT09606 rogid:495Z42oQhkAUdADrAEOKIC5oICo9606 intact-crc:47F77A662C8B9945|rigid:vzyw7fhCsRs8gh1EJVVsESV6LoI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43320 uniprotkb:P07315 intact:EBI-974082|ensembl:ENSP00000381273|ensembl:ENSP00000498905|uniprotkb:Q9UCM8 intact:EBI-6875941|ensembl:ENSP00000282141|ensembl:ENSP00000496418|uniprotkb:Q53R50 psi-mi:crbb2_human(display_long)|uniprotkb:Beta-B2 crystallin(gene name synonym)|uniprotkb:Beta-crystallin Bp(gene name synonym)|uniprotkb:CRYBB2(gene name)|psi-mi:CRYBB2(display_short)|uniprotkb:CRYB2(gene name synonym)|uniprotkb:CRYB2A(gene name synonym) psi-mi:crgc_human(display_long)|uniprotkb:CRYGC(gene name)|psi-mi:CRYGC(display_short)|uniprotkb:CRYG3(gene name synonym)|uniprotkb:Gamma-C-crystallin(gene name synonym)|uniprotkb:Gamma-crystallin 2-1(gene name synonym)|uniprotkb:Gamma-crystallin 3(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) Fu et al. (2002) pubmed:11700327|mint:MINT-5214764 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8034909|mint:MINT-16207 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000244752(gene)|ensembl:ENST00000398215(transcript)|ensembl:ENST00000651629(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0007601"(visual perception)|go:"GO:0042802"(identical protein binding)|go:"GO:0050896"(response to stimulus)|interpro:IPR001064(Beta and gamma crystallin)|interpro:IPR011024(Gamma-crystallin related)|interpro:IPR033058|mint:P43320|rcsb pdb:1YTQ|refseq:NP_000487.1|refseq:XP_011528202.1|refseq:XP_006724204.1|mint:MINT-594326(identity) refseq:XP_011508964.1|ensembl:ENSG00000163254(gene)|ensembl:ENSG00000285011(gene)|ensembl:ENST00000282141(transcript)|ensembl:ENST00000646204(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007601"(visual perception)|interpro:IPR001064(Beta and gamma crystallin)|interpro:IPR011024(Gamma-crystallin related)|mint:P07315|rcsb pdb:1LFE|rcsb pdb:2NBR|refseq:NP_066269.1|mint:MINT-594322(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:"Technique: CAT assay"|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2002/09/06 2014/10/16 rogid:CXsf29udifdbWRxtboJe4mnZAgM9606 rogid:sTGY543Prp3u+F8JqIobyIUsYT09606 intact-crc:DDB0548EE6AA8C4B|rigid:H/4RvcBmdcO/ihs8qV3H2+ertAk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07315 uniprotkb:P02489 intact:EBI-6875941|ensembl:ENSP00000282141|ensembl:ENSP00000496418|uniprotkb:Q53R50 intact:EBI-6875961|ensembl:ENSP00000291554|intact:EBI-25838900|uniprotkb:A0A140G945|uniprotkb:E9PHE4|uniprotkb:Q53X53 psi-mi:crgc_human(display_long)|uniprotkb:CRYGC(gene name)|psi-mi:CRYGC(display_short)|uniprotkb:CRYG3(gene name synonym)|uniprotkb:Gamma-C-crystallin(gene name synonym)|uniprotkb:Gamma-crystallin 2-1(gene name synonym)|uniprotkb:Gamma-crystallin 3(gene name synonym) psi-mi:cryaa_human(display_long)|uniprotkb:CRYAA(gene name)|psi-mi:CRYAA(display_short)|uniprotkb:CRYA1(gene name synonym)|uniprotkb:HSPB4(gene name synonym)|uniprotkb:Heat shock protein beta-4(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) Fu et al. (2002) pubmed:11700327|mint:MINT-5214764 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8034898|mint:MINT-14641 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011508964.1|ensembl:ENSG00000163254(gene)|ensembl:ENSG00000285011(gene)|ensembl:ENST00000282141(transcript)|ensembl:ENST00000646204(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007601"(visual perception)|interpro:IPR001064(Beta and gamma crystallin)|interpro:IPR011024(Gamma-crystallin related)|mint:P07315|rcsb pdb:1LFE|rcsb pdb:2NBR|refseq:NP_066269.1|mint:MINT-594315(identity) refseq:NP_001300979.1|ensembl:ENSG00000160202(gene)|ensembl:ENST00000291554(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050896"(response to stimulus)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR012274(Alpha-crystallin, subunit A)|mint:P02489|rcsb pdb:6T1R|refseq:NP_000385.1|dip:DIP-41265N|mint:MINT-594311(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:"Technique: CAT assay"|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2002/09/06 2014/10/16 rogid:sTGY543Prp3u+F8JqIobyIUsYT09606 rogid:+d2016YcOZzaZpV57L9crFbTzEA9606 intact-crc:A9ED2AD295EFAFFF|rigid:ZYm6x+MhqRA/sP6gzntDpMaKxro false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02489 uniprotkb:P43320 intact:EBI-6875961|ensembl:ENSP00000291554|intact:EBI-25838900|uniprotkb:A0A140G945|uniprotkb:E9PHE4|uniprotkb:Q53X53 intact:EBI-974082|ensembl:ENSP00000381273|ensembl:ENSP00000498905|uniprotkb:Q9UCM8 psi-mi:cryaa_human(display_long)|uniprotkb:CRYAA(gene name)|psi-mi:CRYAA(display_short)|uniprotkb:CRYA1(gene name synonym)|uniprotkb:HSPB4(gene name synonym)|uniprotkb:Heat shock protein beta-4(gene name synonym) psi-mi:crbb2_human(display_long)|uniprotkb:Beta-B2 crystallin(gene name synonym)|uniprotkb:Beta-crystallin Bp(gene name synonym)|uniprotkb:CRYBB2(gene name)|psi-mi:CRYBB2(display_short)|uniprotkb:CRYB2(gene name synonym)|uniprotkb:CRYB2A(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) Fu et al. (2002) pubmed:11700327|mint:MINT-5214764 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8034920|mint:MINT-14199 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001300979.1|ensembl:ENSG00000160202(gene)|ensembl:ENST00000291554(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050896"(response to stimulus)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR012274(Alpha-crystallin, subunit A)|mint:P02489|rcsb pdb:6T1R|refseq:NP_000385.1|dip:DIP-41265N|mint:MINT-594333(identity) ensembl:ENSG00000244752(gene)|ensembl:ENST00000398215(transcript)|ensembl:ENST00000651629(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0007601"(visual perception)|go:"GO:0042802"(identical protein binding)|go:"GO:0050896"(response to stimulus)|interpro:IPR001064(Beta and gamma crystallin)|interpro:IPR011024(Gamma-crystallin related)|interpro:IPR033058|mint:P43320|rcsb pdb:1YTQ|refseq:NP_000487.1|refseq:XP_011528202.1|refseq:XP_006724204.1|mint:MINT-594337(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:"Technique: CAT assay"|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2002/09/06 2014/10/16 rogid:+d2016YcOZzaZpV57L9crFbTzEA9606 rogid:CXsf29udifdbWRxtboJe4mnZAgM9606 intact-crc:B94BA6577CF7D527|rigid:SNcsoFIpwwm6JoqEc3opVAhV8lY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43320 uniprotkb:P02511 intact:EBI-974082|ensembl:ENSP00000381273|ensembl:ENSP00000498905|uniprotkb:Q9UCM8 intact:EBI-739060|uniprotkb:O43416|uniprotkb:B0YIX0|uniprotkb:Q9UC37|uniprotkb:Q9UC38|uniprotkb:Q9UC39|uniprotkb:Q9UC40|uniprotkb:Q9UC41|ensembl:ENSP00000227251|ensembl:ENSP00000433560|ensembl:ENSP00000434247|ensembl:ENSP00000435931|ensembl:ENSP00000436051|ensembl:ENSP00000436089|ensembl:ENSP00000437149|ensembl:ENSP00000483554|ensembl:ENSP00000498735|ensembl:ENSP00000499082 psi-mi:crbb2_human(display_long)|uniprotkb:Beta-B2 crystallin(gene name synonym)|uniprotkb:Beta-crystallin Bp(gene name synonym)|uniprotkb:CRYBB2(gene name)|psi-mi:CRYBB2(display_short)|uniprotkb:CRYB2(gene name synonym)|uniprotkb:CRYB2A(gene name synonym) psi-mi:cryab_human(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-27(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:Rosenthal fiber component(gene name synonym)|uniprotkb:Heat shock protein beta-5(gene name synonym)|uniprotkb:HSPB5(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) Fu et al. (2002) pubmed:11700327|mint:MINT-5214764 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8034942|mint:MINT-17762 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000244752(gene)|ensembl:ENST00000398215(transcript)|ensembl:ENST00000651629(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0007601"(visual perception)|go:"GO:0042802"(identical protein binding)|go:"GO:0050896"(response to stimulus)|interpro:IPR001064(Beta and gamma crystallin)|interpro:IPR011024(Gamma-crystallin related)|interpro:IPR033058|mint:P43320|rcsb pdb:1YTQ|refseq:NP_000487.1|refseq:XP_011528202.1|refseq:XP_006724204.1|mint:MINT-594355(identity) ensembl:ENSG00000109846(gene)|ensembl:ENST00000227251(transcript)|ensembl:ENST00000526180(transcript)|ensembl:ENST00000527899(transcript)|ensembl:ENST00000527950(transcript)|ensembl:ENST00000531198(transcript)|ensembl:ENST00000533475(transcript)|ensembl:ENST00000533879(transcript)|ensembl:ENST00000616970(transcript)|ensembl:ENST00000650687(transcript)|ensembl:ENST00000651164(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P02511|rcsb pdb:2KLR|rcsb pdb:2N0K|rcsb pdb:2WJ7|rcsb pdb:2Y1Y|rcsb pdb:2Y1Z|rcsb pdb:2YGD|rcsb pdb:3J07|rcsb pdb:2Y22|rcsb pdb:3L1G|rcsb pdb:3SGM|rcsb pdb:3SGN|rcsb pdb:3SGO|rcsb pdb:3SGP|rcsb pdb:3SGR|rcsb pdb:3SGS|rcsb pdb:4M5S|rcsb pdb:4M5T|rcsb pdb:5VVV|rcsb pdb:6BP9|reactome:R-HSA-3371571|refseq:NP_001876.1|refseq:XP_011540910.1|refseq:NP_001276736.1|refseq:NP_001276737.1|dip:DIP-35017N|mint:MINT-594359(identity) - comment:"Stoichiometry: 1.0" crc64:AE08BED46B7849CB|comment:"Stoichiometry: 1.0" comment:"Technique: CAT assay"|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2002/09/06 2014/10/16 rogid:CXsf29udifdbWRxtboJe4mnZAgM9606 rogid:495Z42oQhkAUdADrAEOKIC5oICo9606 intact-crc:6540A59A23483933|rigid:uCiSsdOTJidL6Z4xTqVOXkV9Zg4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02489 uniprotkb:P02511 intact:EBI-6875961|ensembl:ENSP00000291554|intact:EBI-25838900|uniprotkb:A0A140G945|uniprotkb:E9PHE4|uniprotkb:Q53X53 intact:EBI-739060|uniprotkb:O43416|uniprotkb:B0YIX0|uniprotkb:Q9UC37|uniprotkb:Q9UC38|uniprotkb:Q9UC39|uniprotkb:Q9UC40|uniprotkb:Q9UC41|ensembl:ENSP00000227251|ensembl:ENSP00000433560|ensembl:ENSP00000434247|ensembl:ENSP00000435931|ensembl:ENSP00000436051|ensembl:ENSP00000436089|ensembl:ENSP00000437149|ensembl:ENSP00000483554|ensembl:ENSP00000498735|ensembl:ENSP00000499082 psi-mi:cryaa_human(display_long)|uniprotkb:CRYAA(gene name)|psi-mi:CRYAA(display_short)|uniprotkb:CRYA1(gene name synonym)|uniprotkb:HSPB4(gene name synonym)|uniprotkb:Heat shock protein beta-4(gene name synonym) psi-mi:cryab_human(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-27(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:Rosenthal fiber component(gene name synonym)|uniprotkb:Heat shock protein beta-5(gene name synonym)|uniprotkb:HSPB5(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) Fu et al. (2002) pubmed:11700327|mint:MINT-5214764 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8034953|mint:MINT-17437 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001300979.1|ensembl:ENSG00000160202(gene)|ensembl:ENST00000291554(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050896"(response to stimulus)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR012274(Alpha-crystallin, subunit A)|mint:P02489|rcsb pdb:6T1R|refseq:NP_000385.1|dip:DIP-41265N|mint:MINT-594366(identity) ensembl:ENSG00000109846(gene)|ensembl:ENST00000227251(transcript)|ensembl:ENST00000526180(transcript)|ensembl:ENST00000527899(transcript)|ensembl:ENST00000527950(transcript)|ensembl:ENST00000531198(transcript)|ensembl:ENST00000533475(transcript)|ensembl:ENST00000533879(transcript)|ensembl:ENST00000616970(transcript)|ensembl:ENST00000650687(transcript)|ensembl:ENST00000651164(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P02511|rcsb pdb:2KLR|rcsb pdb:2N0K|rcsb pdb:2WJ7|rcsb pdb:2Y1Y|rcsb pdb:2Y1Z|rcsb pdb:2YGD|rcsb pdb:3J07|rcsb pdb:2Y22|rcsb pdb:3L1G|rcsb pdb:3SGM|rcsb pdb:3SGN|rcsb pdb:3SGO|rcsb pdb:3SGP|rcsb pdb:3SGR|rcsb pdb:3SGS|rcsb pdb:4M5S|rcsb pdb:4M5T|rcsb pdb:5VVV|rcsb pdb:6BP9|reactome:R-HSA-3371571|refseq:NP_001876.1|refseq:XP_011540910.1|refseq:NP_001276736.1|refseq:NP_001276737.1|dip:DIP-35017N|mint:MINT-594370(identity) - comment:"Stoichiometry: 1.0" crc64:AE08BED46B7849CB|comment:"Stoichiometry: 1.0" comment:"Technique: CAT assay"|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2002/09/06 2014/10/16 rogid:+d2016YcOZzaZpV57L9crFbTzEA9606 rogid:495Z42oQhkAUdADrAEOKIC5oICo9606 intact-crc:0DA12A9DBDBB3BE8|rigid:eoEnEMVeStMxBOplzJofsa8Ar1k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)