#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9UBS0	uniprotkb:O00418	intact:EBI-3905921|uniprotkb:B2RMZ9|uniprotkb:O94809|uniprotkb:Q9UEC1|ensembl:ENSP00000308413|uniprotkb:B4DML8	intact:EBI-6255306|ensembl:ENSP00000263026|uniprotkb:Q8N588	psi-mi:ks6b2_human(display_long)|uniprotkb:RPS6KB2(gene name)|psi-mi:RPS6KB2(display_short)|uniprotkb:STK14B(gene name synonym)|uniprotkb:70 kDa ribosomal protein S6 kinase 2(gene name synonym)|uniprotkb:S6 kinase-related kinase(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 14B(gene name synonym)|uniprotkb:p70 ribosomal S6 kinase beta(gene name synonym)	psi-mi:ef2k_human(display_long)|uniprotkb:EEF2K(gene name)|psi-mi:EEF2K(display_short)|uniprotkb:Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase(gene name synonym)	psi-mi:"MI:0045"(experimental interaction detection)	Wang et al. (2001)	pubmed:11500364|mint:MINT-5214384	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7922589|mint:MINT-15495	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003943.2|ensembl:ENSG00000175634(gene)|ensembl:ENST00000312629(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004711"(ribosomal protein S6 kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0007165"(signal transduction)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031929"(TOR signaling)|go:"GO:0042277"(peptide binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016238(Ribosomal protein S6 kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:Q9UBS0|reactome:R-HSA-198693|reactome:R-HSA-5674400|mint:MINT-584837(identity)	ensembl:ENSG00000103319(gene)|ensembl:ENST00000263026(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004686"(elongation factor-2 kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071454"(cellular response to anoxia)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:1990637"(response to prolactin)|interpro:IPR004166(MHCK/EF2 kinase)|interpro:IPR006597(Sel1-like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR017400(Elongation factor 2 kinase)|mint:O00418|rcsb pdb:5J8H|rcsb pdb:5KS5|rcsb pdb:6NX4|reactome:R-HSA-166208|refseq:XP_016878682.1|refseq:XP_005276554.1|refseq:NP_037434.1|mint:MINT-584841(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2002/08/27	2014/10/16	rogid:5+kV2nr99KWLmrnfXt7Vr6L83xM9606	rogid:qrRXhq46QxCng73Y76CB+F3Ya0c9606	intact-crc:EF25160B340172C0|rigid:UXNhdF/WJ3ufege7/YlQ9DXZHN0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O00418	uniprotkb:Q15418	intact:EBI-6255306|ensembl:ENSP00000263026|uniprotkb:Q8N588	intact:EBI-963034|uniprotkb:A6NGG4|intact:EBI-1383804|uniprotkb:A8K9K7|uniprotkb:B7Z5J0|ensembl:ENSP00000363283|ensembl:ENSP00000486881|uniprotkb:Q5SVM5|uniprotkb:Q5SVM8|uniprotkb:Q5SVM9|uniprotkb:Q96C05|uniprotkb:Q9BQK2|uniprotkb:B2RDY8|uniprotkb:E9PRI4	psi-mi:ef2k_human(display_long)|uniprotkb:EEF2K(gene name)|psi-mi:EEF2K(display_short)|uniprotkb:Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase(gene name synonym)	psi-mi:ks6a1_human(display_long)|uniprotkb:RPS6KA1(gene name)|psi-mi:RPS6KA1(display_short)|uniprotkb:RSK1(gene name synonym)|uniprotkb:90 kDa ribosomal protein S6 kinase 1(gene name synonym)|uniprotkb:MAPKAPK1A(gene name synonym)|uniprotkb:Ribosomal S6 kinase 1(gene name synonym)|uniprotkb:MAP kinase-activated protein kinase 1a(gene name synonym)	psi-mi:"MI:0045"(experimental interaction detection)	Wang et al. (2001)	pubmed:11500364|mint:MINT-5214384	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7922677|mint:MINT-17060	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000103319(gene)|ensembl:ENST00000263026(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004686"(elongation factor-2 kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071454"(cellular response to anoxia)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:1990637"(response to prolactin)|interpro:IPR004166(MHCK/EF2 kinase)|interpro:IPR006597(Sel1-like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR017400(Elongation factor 2 kinase)|mint:O00418|rcsb pdb:5J8H|rcsb pdb:5KS5|rcsb pdb:6NX4|reactome:R-HSA-166208|refseq:XP_016878682.1|refseq:XP_005276554.1|refseq:NP_037434.1|mint:MINT-584851(identity)	ensembl:ENSG00000117676(gene)|ensembl:ENSG00000281877(gene)|ensembl:ENST00000374168(transcript)|ensembl:ENST00000629832(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004711"(ribosomal protein S6 kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072574"(hepatocyte proliferation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0106311"|go:"GO:2000491"(positive regulation of hepatic stellate cell activation)|interpro:IPR000719(Protein kinase, core)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|interpro:IPR008271(Serine/threonine protein kinase, active site)|go:"GO:0043066"(negative regulation of apoptotic process)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016239(Ribosomal protein S6 kinase II)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR041906|mint:Q15418|rcsb pdb:2WNT|go:"GO:0043555"(regulation of translation in response to stress)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|rcsb pdb:2Z7Q|rcsb pdb:2Z7R|rcsb pdb:2Z7S|rcsb pdb:3RNY|go:"GO:0045202"(synapse)|rcsb pdb:3TEI|go:"GO:0045597"(positive regulation of cell differentiation)|rcsb pdb:4H3P|rcsb pdb:4NIF|rcsb pdb:5CSF|rcsb pdb:5CSI|rcsb pdb:5CSJ|rcsb pdb:5CSN|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:5V61|rcsb pdb:5V62|rcsb pdb:6TWY|reactome:R-HSA-198753|reactome:R-HSA-199920|reactome:R-HSA-2559582|reactome:R-HSA-437239|reactome:R-HSA-442742|reactome:R-HSA-444257|reactome:R-HSA-881907|refseq:NP_001006666.1|refseq:NP_002944.2|refseq:NP_001317370.1|dip:DIP-29987N|mint:MINT-584847(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2002/08/27	2014/10/16	rogid:qrRXhq46QxCng73Y76CB+F3Ya0c9606	rogid:kx+9PwIH4KR0iTxpv6epDKNqHBE9606	intact-crc:CD111266E3BAA7B7|rigid:D+kmrzOrBEgVewF9oBNRq3Wtk98	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)