#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P15863 uniprotkb:P50221 intact:EBI-7885202|uniprotkb:Q6NTC0|uniprotkb:Q9Y558|uniprotkb:Q642X9|intact:MINT-202824|uniprotkb:B4E0D6|ensembl:ENSP00000381499 intact:EBI-2864512|uniprotkb:A8K524|uniprotkb:Q15069|uniprotkb:A8MWF9|ensembl:ENSP00000321684 psi-mi:pax1_human(display_long)|uniprotkb:PAX1(gene name)|psi-mi:PAX1(display_short)|uniprotkb:HUP48(gene name synonym)|uniprotkb:HuP48(gene name synonym) psi-mi:meox1_human(display_long)|uniprotkb:MEOX1(gene name)|psi-mi:MEOX1(display_short)|uniprotkb:MOX1(gene name synonym)|uniprotkb:Mesenchyme homeobox 1(gene name synonym) psi-mi:"MI:0096"(pull down) Stamataki et al. (2001) pubmed:11423130|mint:MINT-5214203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7885253|mint:MINT-17255 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006183.2|ensembl:ENSP00000381499|ensembl:ENST00000444366|ensembl:ENSP00000410355|ensembl:ENSG00000125813(gene)|ensembl:ENST00000398485(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR033206|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|mint:MINT-580033(identity) refseq:NP_001035091.1|refseq:NP_004518.1|refseq:NP_054705.1|ensembl:ENSG00000005102(gene)|ensembl:ENST00000318579(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001757"(somite specification)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061053"(somite development)|go:"GO:0061056"(sclerotome development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|mint:MINT-580027(identity) - comment:mint|function:This protein is a transcriptional activator. It may play a role in the formation of segmented structures of the embryo. May play an important role in the normal development of the vertebral column|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2002/02/08 2014/10/16 rogid:9Se/IEMBo7Uil3wvDBLlhWvZ/Ic9606 rogid:yBbzuzEOADdUkAmwCSLI6+yosC09606 intact-crc:F5BD3C39FB4CD3C4|rigid:dId6ALbYQ1z3o7skPJ9eSRgovfE false - binding-associated region:134-253(MINT-580028) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50222 uniprotkb:P23760 intact:EBI-748397|uniprotkb:O75263|ensembl:ENSP00000262041|uniprotkb:Q9UPL6|uniprotkb:B2R8I7|intact:EBI-10172134|intact:EBI-11522964|intact:EBI-11750003|intact:EBI-12702266|uniprotkb:A4D127 intact:EBI-1167564|uniprotkb:Q16448|uniprotkb:Q53T90|uniprotkb:Q6GSJ9|uniprotkb:Q86UQ2|uniprotkb:Q86UQ3|uniprotkb:Q494Z3|uniprotkb:Q494Z4|uniprotkb:G5E9C1|ensembl:ENSP00000343052 psi-mi:meox2_human(display_long)|uniprotkb:Mesenchyme homeobox 2(gene name synonym)|uniprotkb:Growth arrest-specific homeobox(gene name synonym)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)|uniprotkb:GAX(gene name synonym)|uniprotkb:MOX2(gene name synonym) psi-mi:pax3_human(display_long)|uniprotkb:PAX3(gene name)|psi-mi:PAX3(display_short)|uniprotkb:HUP2(gene name synonym)|uniprotkb:HuP2(gene name synonym) psi-mi:"MI:0096"(pull down) Stamataki et al. (2001) pubmed:11423130|mint:MINT-5214203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7885294|mint:MINT-15279 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000106511(gene)|ensembl:ENST00000262041(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001757"(somite specification)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008015"(blood circulation)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060173"(limb development)|go:"GO:0061053"(somite development)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|refseq:NP_005915.2|mint:MINT-580077(identity) refseq:NP_000429.2|refseq:NP_039230.1|refseq:NP_852122.1|refseq:NP_001120838.1|refseq:NP_852123.1|refseq:NP_852124.1|refseq:NP_852125.1|refseq:NP_852126.1|ensembl:ENSG00000135903(gene)|ensembl:ENST00000350526(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022106|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|mint:P23760|rcsb pdb:3CMY|reactome:R-HSA-3214847|mint:MINT-580083(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2002/02/08 2014/10/16 rogid:fMv0ruKikzQ3MC0PBvJ3pOAjW+U9606 rogid:W/MFjTf3d4mRzCXRWgl0sk/mdX49606 intact-crc:6744135B539BDDE2|rigid:l4txyy8ESnf9+B3VWpzZByL30+A false binding-associated region:151-303(MINT-580078) binding-associated region:230-479(MINT-580084) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50222 uniprotkb:P23760 intact:EBI-748397|uniprotkb:O75263|ensembl:ENSP00000262041|uniprotkb:Q9UPL6|uniprotkb:B2R8I7|intact:EBI-10172134|intact:EBI-11522964|intact:EBI-11750003|intact:EBI-12702266|uniprotkb:A4D127 intact:EBI-1167564|uniprotkb:Q16448|uniprotkb:Q53T90|uniprotkb:Q6GSJ9|uniprotkb:Q86UQ2|uniprotkb:Q86UQ3|uniprotkb:Q494Z3|uniprotkb:Q494Z4|uniprotkb:G5E9C1|ensembl:ENSP00000343052 psi-mi:meox2_human(display_long)|uniprotkb:Mesenchyme homeobox 2(gene name synonym)|uniprotkb:Growth arrest-specific homeobox(gene name synonym)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)|uniprotkb:GAX(gene name synonym)|uniprotkb:MOX2(gene name synonym) psi-mi:pax3_human(display_long)|uniprotkb:PAX3(gene name)|psi-mi:PAX3(display_short)|uniprotkb:HUP2(gene name synonym)|uniprotkb:HuP2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Stamataki et al. (2001) pubmed:11423130|mint:MINT-5214203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7885339|mint:MINT-15278 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000106511(gene)|ensembl:ENST00000262041(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001757"(somite specification)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008015"(blood circulation)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060173"(limb development)|go:"GO:0061053"(somite development)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|refseq:NP_005915.2|mint:MINT-580040(identity) refseq:NP_000429.2|refseq:NP_039230.1|refseq:NP_852122.1|refseq:NP_001120838.1|refseq:NP_852123.1|refseq:NP_852124.1|refseq:NP_852125.1|refseq:NP_852126.1|ensembl:ENSG00000135903(gene)|ensembl:ENST00000350526(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022106|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|mint:P23760|rcsb pdb:3CMY|reactome:R-HSA-3214847|mint:MINT-580049(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:homomint|comment:mint taxid:-4(in vivo)|taxid:-4(in vivo) - 2002/02/08 2014/10/16 rogid:fMv0ruKikzQ3MC0PBvJ3pOAjW+U9606 rogid:W/MFjTf3d4mRzCXRWgl0sk/mdX49606 intact-crc:AAE47797D3F27D66|rigid:l4txyy8ESnf9+B3VWpzZByL30+A false tag:?-?(MINT-580044)|binding-associated region:151-303(MINT-580041) binding-associated region:230-479(MINT-580050)|tag:?-?(MINT-580053) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P15863 uniprotkb:P50221 intact:EBI-7885202|uniprotkb:Q6NTC0|uniprotkb:Q9Y558|uniprotkb:Q642X9|intact:MINT-202824|uniprotkb:B4E0D6|ensembl:ENSP00000381499 intact:EBI-2864512|uniprotkb:A8K524|uniprotkb:Q15069|uniprotkb:A8MWF9|ensembl:ENSP00000321684 psi-mi:pax1_human(display_long)|uniprotkb:PAX1(gene name)|psi-mi:PAX1(display_short)|uniprotkb:HUP48(gene name synonym)|uniprotkb:HuP48(gene name synonym) psi-mi:meox1_human(display_long)|uniprotkb:MEOX1(gene name)|psi-mi:MEOX1(display_short)|uniprotkb:MOX1(gene name synonym)|uniprotkb:Mesenchyme homeobox 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Stamataki et al. (2001) pubmed:11423130|mint:MINT-5214203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7885365|mint:MINT-17254 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006183.2|ensembl:ENSP00000381499|ensembl:ENST00000444366|ensembl:ENSP00000410355|ensembl:ENSG00000125813(gene)|ensembl:ENST00000398485(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR033206|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|mint:MINT-580069(identity) refseq:NP_001035091.1|refseq:NP_004518.1|refseq:NP_054705.1|ensembl:ENSG00000005102(gene)|ensembl:ENST00000318579(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001757"(somite specification)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061053"(somite development)|go:"GO:0061056"(sclerotome development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|mint:MINT-580060(identity) - comment:mint|function:This protein is a transcriptional activator. It may play a role in the formation of segmented structures of the embryo. May play an important role in the normal development of the vertebral column|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:homomint|comment:mint taxid:-4(in vivo)|taxid:-4(in vivo) - 2002/02/08 2014/10/16 rogid:9Se/IEMBo7Uil3wvDBLlhWvZ/Ic9606 rogid:yBbzuzEOADdUkAmwCSLI6+yosC09606 intact-crc:A41DB6F52B88B0CD|rigid:dId6ALbYQ1z3o7skPJ9eSRgovfE false tag:?-?(MINT-580070) binding-associated region:134-253(MINT-580061)|tag:?-?(MINT-580064) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)