#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P09989 uniprotkb:Q9UI95 intact:EBI-7802801|intact:MINT-193117 intact:EBI-77889|ensembl:ENSP00000235310|ensembl:ENSP00000365855|ensembl:ENSP00000365882|uniprotkb:Q5TGW7|uniprotkb:Q9UNA7|uniprotkb:Q9Y6I6|uniprotkb:B3KNE3 psi-mi:ript_triki(display_long)|uniprotkb:rRNA N-glycosidase(gene name synonym) psi-mi:md2l2_human(display_long)|uniprotkb:MAD2L2(gene name)|psi-mi:MAD2L2(display_short)|uniprotkb:MAD2B(gene name synonym)|uniprotkb:REV7(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 2(gene name synonym)|uniprotkb:REV7 homolog(gene name synonym) psi-mi:"MI:0049"(filter binding) Chan et al. (2001) pubmed:11277934|mint:MINT-5213788|doi:10.1046/j.1432-1327.2001.02091 taxid:3677(triki)|taxid:3677(Trichosanthes kirilowii) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7802926|mint:MINT-15762 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006952"(defense response)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030598"(rRNA N-glycosylase activity)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0090729"(toxin activity)|rcsb pdb:1MRK|rcsb pdb:2JDL|rcsb pdb:1NLI|rcsb pdb:1J4G|rcsb pdb:2VS6|interpro:IPR017989|rcsb pdb:1GIS|rcsb pdb:1MRJ|rcsb pdb:2JJR|interpro:IPR017988|rcsb pdb:1QD2|interpro:IPR016138(Ribosome-inactivating protein, subdomain 1)|rcsb pdb:1TCS|interpro:IPR016139(Ribosome-inactivating protein, subdomain 2)|rcsb pdb:1GIU|interpro:IPR001574(Ribosome-inactivating protein)|interpro:IPR036041|mint:MINT-471325(identity) ensembl:ENSG00000116670(gene)|ensembl:ENST00000235310(transcript)|ensembl:ENST00000376667(transcript)|ensembl:ENST00000376692(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007015"(actin filament organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0016035"(zeta DNA polymerase complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042772"(DNA damage response, signal transduction resulting in transcription)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|rcsb pdb:3ABD|rcsb pdb:3ABE|rcsb pdb:3VU7|rcsb pdb:4EXT|rcsb pdb:4GK0|rcsb pdb:4GK5|rcsb pdb:5XPT|rcsb pdb:5XPU|rcsb pdb:6BC8|rcsb pdb:6BCD|rcsb pdb:6BI7|rcsb pdb:6K07|rcsb pdb:6K08|rcsb pdb:6KEA|rcsb pdb:6KTO|rcsb pdb:6M7A|rcsb pdb:6M7B|rcsb pdb:6NIF|rcsb pdb:6VE5|rcsb pdb:6WS0|rcsb pdb:6WS5|rcsb pdb:6WW9|rcsb pdb:6WWA|rcsb pdb:7L9P|reactome:R-HSA-110312|reactome:R-HSA-5655862|reactome:R-HSA-5656121|refseq:NP_001120797.1|refseq:NP_006332.3|refseq:XP_011538809.1|mint:MINT-471328(identity) - comment:mint|function:Inactivates eukaryotic 60S ribosomal subunits|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2002/04/26 2014/10/16 rogid:yLodUyK46Q0Vwt+1tHTS+Q1TZXQ3677 rogid:KBeawMhcP3iXUel74pUDl85A/vw9606 intact-crc:F2211BAE468306E1|rigid:p5WCqD1eBYQn7bXjYyvhb4qaGlw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09989 uniprotkb:P05386 intact:EBI-7802801|intact:MINT-193117 intact:EBI-354582|uniprotkb:A6NIB2|ensembl:ENSP00000346037 psi-mi:ript_triki(display_long)|uniprotkb:rRNA N-glycosidase(gene name synonym) psi-mi:rla1_human(display_long)|uniprotkb:RPLP1(gene name)|psi-mi:RPLP1(display_short)|uniprotkb:RRP1(gene name synonym)|uniprotkb:Large ribosomal subunit protein P1(gene name synonym) psi-mi:"MI:0049"(filter binding) Chan et al. (2001) pubmed:11277934|mint:MINT-5213788|doi:10.1046/j.1432-1327.2001.02091 taxid:3677(triki)|taxid:3677(Trichosanthes kirilowii) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7802828|mint:MINT-17228 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006952"(defense response)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030598"(rRNA N-glycosylase activity)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0090729"(toxin activity)|rcsb pdb:1MRK|rcsb pdb:2JDL|rcsb pdb:1NLI|rcsb pdb:1J4G|rcsb pdb:2VS6|interpro:IPR017989|rcsb pdb:1GIS|rcsb pdb:1MRJ|rcsb pdb:2JJR|interpro:IPR017988|rcsb pdb:1QD2|interpro:IPR016138(Ribosome-inactivating protein, subdomain 1)|rcsb pdb:1TCS|interpro:IPR016139(Ribosome-inactivating protein, subdomain 2)|rcsb pdb:1GIU|interpro:IPR001574(Ribosome-inactivating protein)|interpro:IPR036041|mint:MINT-471301(identity) refseq:NP_000994.1|refseq:NP_998890.1|ensembl:ENSG00000137818(gene)|ensembl:ENST00000260379(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR027534|interpro:IPR038716|mint:P05386|rcsb pdb:2LBF|rcsb pdb:4BEH|rcsb pdb:4V6X|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|mint:MINT-471304(identity) - comment:mint|function:Inactivates eukaryotic 60S ribosomal subunits|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2002/04/26 2014/10/16 rogid:yLodUyK46Q0Vwt+1tHTS+Q1TZXQ3677 rogid:rHSXz4ZCJy+JH6OrjUgHiTK85mo9606 intact-crc:C67AD42A62362DE2|rigid:dqg02AXw+Bwy/vFGcLNzoxTPX+k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09989 uniprotkb:P05388 intact:EBI-7802801|intact:MINT-193117 intact:EBI-354101|uniprotkb:Q9BVK4|intact:EBI-8012155|intact:MINT-8395053|uniprotkb:Q3B7A4|ensembl:ENSP00000339027|ensembl:ENSP00000376299|ensembl:ENSP00000449328 psi-mi:ript_triki(display_long)|uniprotkb:rRNA N-glycosidase(gene name synonym) psi-mi:rla0_human(display_long)|uniprotkb:RPLP0(gene name)|psi-mi:RPLP0(display_short)|uniprotkb:60S ribosomal protein L10E(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL10(gene name synonym) psi-mi:"MI:0049"(filter binding) Chan et al. (2001) pubmed:11277934|mint:MINT-5213788|doi:10.1046/j.1432-1327.2001.02091 taxid:3677(triki)|taxid:3677(Trichosanthes kirilowii) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7802935|mint:MINT-15886 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006952"(defense response)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030598"(rRNA N-glycosylase activity)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0090729"(toxin activity)|rcsb pdb:1MRK|rcsb pdb:2JDL|rcsb pdb:1NLI|rcsb pdb:1J4G|rcsb pdb:2VS6|interpro:IPR017989|rcsb pdb:1GIS|rcsb pdb:1MRJ|rcsb pdb:2JJR|interpro:IPR017988|rcsb pdb:1QD2|interpro:IPR016138(Ribosome-inactivating protein, subdomain 1)|rcsb pdb:1TCS|interpro:IPR016139(Ribosome-inactivating protein, subdomain 2)|rcsb pdb:1GIU|interpro:IPR001574(Ribosome-inactivating protein)|interpro:IPR036041|mint:MINT-471333(identity) refseq:NP_000993.1|refseq:NP_444505.1|ensembl:ENSG00000089157(gene)|ensembl:ENST00000228306(transcript)|ensembl:ENST00000392514(transcript)|ensembl:ENST00000551150(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0098794"(postsynapse)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR030670|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|mint:P05388|rcsb pdb:4V6W|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:6OLG|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-8950505|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|mint:MINT-471336(identity) - comment:mint|function:Inactivates eukaryotic 60S ribosomal subunits|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2002/04/26 2014/10/16 rogid:yLodUyK46Q0Vwt+1tHTS+Q1TZXQ3677 rogid:xv3QHqnXxvCd3BOIeHVkqEnSNNk9606 intact-crc:22ADF374156B340E|rigid:3kKqpbH5bjM40Zz9WqWoZ3Pg/YU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09989 uniprotkb:P05388 intact:EBI-7802801|intact:MINT-193117 intact:EBI-354101|uniprotkb:Q9BVK4|intact:EBI-8012155|intact:MINT-8395053|uniprotkb:Q3B7A4|ensembl:ENSP00000339027|ensembl:ENSP00000376299|ensembl:ENSP00000449328 psi-mi:ript_triki(display_long)|uniprotkb:rRNA N-glycosidase(gene name synonym) psi-mi:rla0_human(display_long)|uniprotkb:RPLP0(gene name)|psi-mi:RPLP0(display_short)|uniprotkb:60S ribosomal protein L10E(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL10(gene name synonym) psi-mi:"MI:0018"(two hybrid) Chan et al. (2001) pubmed:11277934|mint:MINT-5213788|doi:10.1046/j.1432-1327.2001.02091 taxid:3677(triki)|taxid:3677(Trichosanthes kirilowii) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7802951|mint:MINT-15885 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006952"(defense response)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030598"(rRNA N-glycosylase activity)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0090729"(toxin activity)|rcsb pdb:1MRK|rcsb pdb:2JDL|rcsb pdb:1NLI|rcsb pdb:1J4G|rcsb pdb:2VS6|interpro:IPR017989|rcsb pdb:1GIS|rcsb pdb:1MRJ|rcsb pdb:2JJR|interpro:IPR017988|rcsb pdb:1QD2|interpro:IPR016138(Ribosome-inactivating protein, subdomain 1)|rcsb pdb:1TCS|interpro:IPR016139(Ribosome-inactivating protein, subdomain 2)|rcsb pdb:1GIU|interpro:IPR001574(Ribosome-inactivating protein)|interpro:IPR036041|mint:MINT-471311(identity) refseq:NP_000993.1|refseq:NP_444505.1|ensembl:ENSG00000089157(gene)|ensembl:ENST00000228306(transcript)|ensembl:ENST00000392514(transcript)|ensembl:ENST00000551150(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0098794"(postsynapse)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR030670|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|mint:P05388|rcsb pdb:4V6W|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:6OLG|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-8950505|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|mint:MINT-471317(identity) - comment:mint|function:Inactivates eukaryotic 60S ribosomal subunits|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:mint taxid:-4(in vivo)|taxid:-4(in vivo) - 2002/04/26 2014/10/16 rogid:yLodUyK46Q0Vwt+1tHTS+Q1TZXQ3677 rogid:xv3QHqnXxvCd3BOIeHVkqEnSNNk9606 intact-crc:AE095677CDDBF73A|rigid:3kKqpbH5bjM40Zz9WqWoZ3Pg/YU false tag:?-?(MINT-471312) tag:?-?(MINT-471318) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09989 uniprotkb:P05386 intact:EBI-7802801|intact:MINT-193117 intact:EBI-354582|uniprotkb:A6NIB2|ensembl:ENSP00000346037 psi-mi:ript_triki(display_long)|uniprotkb:rRNA N-glycosidase(gene name synonym) psi-mi:rla1_human(display_long)|uniprotkb:RPLP1(gene name)|psi-mi:RPLP1(display_short)|uniprotkb:RRP1(gene name synonym)|uniprotkb:Large ribosomal subunit protein P1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Chan et al. (2001) pubmed:11277934|mint:MINT-5213788|doi:10.1046/j.1432-1327.2001.02091 taxid:3677(triki)|taxid:3677(Trichosanthes kirilowii) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7802981|mint:MINT-17227 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006952"(defense response)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030598"(rRNA N-glycosylase activity)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0090729"(toxin activity)|rcsb pdb:1MRK|rcsb pdb:2JDL|rcsb pdb:1NLI|rcsb pdb:1J4G|rcsb pdb:2VS6|interpro:IPR017989|rcsb pdb:1GIS|rcsb pdb:1MRJ|rcsb pdb:2JJR|interpro:IPR017988|rcsb pdb:1QD2|interpro:IPR016138(Ribosome-inactivating protein, subdomain 1)|rcsb pdb:1TCS|interpro:IPR016139(Ribosome-inactivating protein, subdomain 2)|rcsb pdb:1GIU|interpro:IPR001574(Ribosome-inactivating protein)|interpro:IPR036041|mint:MINT-471355(identity) refseq:NP_000994.1|refseq:NP_998890.1|ensembl:ENSG00000137818(gene)|ensembl:ENST00000260379(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR027534|interpro:IPR038716|mint:P05386|rcsb pdb:2LBF|rcsb pdb:4BEH|rcsb pdb:4V6X|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|mint:MINT-471361(identity) - comment:mint|function:Inactivates eukaryotic 60S ribosomal subunits|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:mint taxid:-4(in vivo)|taxid:-4(in vivo) - 2002/04/26 2014/10/16 rogid:yLodUyK46Q0Vwt+1tHTS+Q1TZXQ3677 rogid:rHSXz4ZCJy+JH6OrjUgHiTK85mo9606 intact-crc:7275B33B44CC4B6B|rigid:dqg02AXw+Bwy/vFGcLNzoxTPX+k false tag:?-?(MINT-471356) tag:?-?(MINT-471362) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P09989 uniprotkb:Q9UI95 intact:EBI-7802801|intact:MINT-193117 intact:EBI-77889|ensembl:ENSP00000235310|ensembl:ENSP00000365855|ensembl:ENSP00000365882|uniprotkb:Q5TGW7|uniprotkb:Q9UNA7|uniprotkb:Q9Y6I6|uniprotkb:B3KNE3 psi-mi:ript_triki(display_long)|uniprotkb:rRNA N-glycosidase(gene name synonym) psi-mi:md2l2_human(display_long)|uniprotkb:MAD2L2(gene name)|psi-mi:MAD2L2(display_short)|uniprotkb:MAD2B(gene name synonym)|uniprotkb:REV7(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 2(gene name synonym)|uniprotkb:REV7 homolog(gene name synonym) psi-mi:"MI:0018"(two hybrid) Chan et al. (2001) pubmed:11277934|mint:MINT-5213788|doi:10.1046/j.1432-1327.2001.02091 taxid:3677(triki)|taxid:3677(Trichosanthes kirilowii) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7802966|mint:MINT-15761 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006952"(defense response)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030598"(rRNA N-glycosylase activity)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0090729"(toxin activity)|rcsb pdb:1MRK|rcsb pdb:2JDL|rcsb pdb:1NLI|rcsb pdb:1J4G|rcsb pdb:2VS6|interpro:IPR017989|rcsb pdb:1GIS|rcsb pdb:1MRJ|rcsb pdb:2JJR|interpro:IPR017988|rcsb pdb:1QD2|interpro:IPR016138(Ribosome-inactivating protein, subdomain 1)|rcsb pdb:1TCS|interpro:IPR016139(Ribosome-inactivating protein, subdomain 2)|rcsb pdb:1GIU|interpro:IPR001574(Ribosome-inactivating protein)|interpro:IPR036041|mint:MINT-471341(identity) ensembl:ENSG00000116670(gene)|ensembl:ENST00000235310(transcript)|ensembl:ENST00000376667(transcript)|ensembl:ENST00000376692(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007015"(actin filament organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0016035"(zeta DNA polymerase complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042772"(DNA damage response, signal transduction resulting in transcription)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|rcsb pdb:3ABD|rcsb pdb:3ABE|rcsb pdb:3VU7|rcsb pdb:4EXT|rcsb pdb:4GK0|rcsb pdb:4GK5|rcsb pdb:5XPT|rcsb pdb:5XPU|rcsb pdb:6BC8|rcsb pdb:6BCD|rcsb pdb:6BI7|rcsb pdb:6K07|rcsb pdb:6K08|rcsb pdb:6KEA|rcsb pdb:6KTO|rcsb pdb:6M7A|rcsb pdb:6M7B|rcsb pdb:6NIF|rcsb pdb:6VE5|rcsb pdb:6WS0|rcsb pdb:6WS5|rcsb pdb:6WW9|rcsb pdb:6WWA|rcsb pdb:7L9P|reactome:R-HSA-110312|reactome:R-HSA-5655862|reactome:R-HSA-5656121|refseq:NP_001120797.1|refseq:NP_006332.3|refseq:XP_011538809.1|mint:MINT-471347(identity) - comment:mint|function:Inactivates eukaryotic 60S ribosomal subunits|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:mint taxid:-4(in vivo)|taxid:-4(in vivo) - 2002/04/26 2014/10/16 rogid:yLodUyK46Q0Vwt+1tHTS+Q1TZXQ3677 rogid:KBeawMhcP3iXUel74pUDl85A/vw9606 intact-crc:F008EF1F635E2584|rigid:p5WCqD1eBYQn7bXjYyvhb4qaGlw false tag:?-?(MINT-471342) tag:?-?(MINT-471348) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)