#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q99PI8	uniprotkb:Q99P72	intact:EBI-7766036|ensembl:ENSMUSP00000062924|uniprotkb:Q80WQ1|intact:MINT-188355	intact:EBI-3869532|uniprotkb:Q8BHF5|uniprotkb:Q78NS1|uniprotkb:Q8BH78|uniprotkb:Q5DTK9|uniprotkb:Q7TNB7|uniprotkb:Q80W95|uniprotkb:Q8BGK7|uniprotkb:Q8BGM9|uniprotkb:Q8K290|uniprotkb:Q8K3G8|uniprotkb:Q9CTE3|ensembl:ENSMUSP00000099907	psi-mi:rtn4r_mouse(display_long)|uniprotkb:Ngr1(gene name synonym)|uniprotkb:Nogo66 receptor-1(gene name synonym)|uniprotkb:Rtn4r(gene name)|psi-mi:Rtn4r(display_short)|uniprotkb:Nogor(gene name synonym)|uniprotkb:Nogo receptor(gene name synonym)|uniprotkb:Nogo-66 receptor(gene name synonym)	psi-mi:rtn4_mouse(display_long)|uniprotkb:Rtn4(gene name)|psi-mi:Rtn4(display_short)|uniprotkb:Kiaa0886(gene name synonym)|uniprotkb:Nogo(gene name synonym)|uniprotkb:Neurite outgrowth inhibitor(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Fournier et al. (2001)	pubmed:11201742|mint:MINT-5213544	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7766067|mint:MINT-15772	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000043811(gene)|ensembl:ENSMUST00000059589(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008201"(heparin binding)|go:"GO:0009986"(cell surface)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0023041"(neuronal signal transduction)|go:"GO:0030426"(growth cone)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035374"(chondroitin sulfate binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0038131"(neuregulin receptor activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048495"(Roundabout binding)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905573"(ganglioside GM1 binding)|go:"GO:1905576"(ganglioside GT1b binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|mint:Q99PI8|rcsb pdb:5O0K|rcsb pdb:5O0L|rcsb pdb:5O0M|rcsb pdb:5O0N|rcsb pdb:5O0O|rcsb pdb:5O0Q|rcsb pdb:5O0R|rcsb pdb:5O0P|refseq:NP_075358.1|mint:MINT-468222(identity)	refseq:NP_077188.1|refseq:NP_918940.1|refseq:NP_918943.1|dip:DIP-41976N|ensembl:ENSMUSG00000020458(gene)|ensembl:ENSMUST00000102843(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007399"(nervous system development)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021801"(cerebral cortex radial glia-guided migration)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0033603"(positive regulation of dopamine secretion)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0035441"(cell migration involved in vasculogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045687"(positive regulation of glial cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0051960"(regulation of nervous system development)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0070571"(negative regulation of neuron projection regeneration)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0120078"(cell adhesion involved in sprouting angiogenesis)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902624"(positive regulation of neutrophil migration)|go:"GO:1905523"(positive regulation of macrophage migration)|go:"GO:1905552"(positive regulation of protein localization to endoplasmic reticulum)|go:"GO:1905580"(positive regulation of ERBB3 signaling pathway)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|go:"GO:2000172"(regulation of branching morphogenesis of a nerve)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001213"(negative regulation of vasculogenesis)|interpro:IPR003388(Reticulon)|mint:Q99P72|rcsb pdb:2KO2|reactome:R-MMU-193634|refseq:NP_918941.1|refseq:NP_918942.1|mint:MINT-468217(identity)	-	comment:mint|function:Receptor for RTN4, OMG and MAG. Mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2002/07/26	2014/10/16	rogid:TQ/XncSvF4z/pYDIDf7gNZk8b8010090	rogid:+hmGWVeJPIbs6/SavXBsKK22Nqw10090	intact-crc:C239EA98E1C4070F|rigid:XVTQNVL2w26eRld1T/GuLPvZ8mc	false	-	binding-associated region:51-137(MINT-468218)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99PI8	uniprotkb:Q99P72	intact:EBI-7766036|ensembl:ENSMUSP00000062924|uniprotkb:Q80WQ1|intact:MINT-188355	intact:EBI-3869532|uniprotkb:Q8BHF5|uniprotkb:Q78NS1|uniprotkb:Q8BH78|uniprotkb:Q5DTK9|uniprotkb:Q7TNB7|uniprotkb:Q80W95|uniprotkb:Q8BGK7|uniprotkb:Q8BGM9|uniprotkb:Q8K290|uniprotkb:Q8K3G8|uniprotkb:Q9CTE3|ensembl:ENSMUSP00000099907	psi-mi:rtn4r_mouse(display_long)|uniprotkb:Ngr1(gene name synonym)|uniprotkb:Nogo66 receptor-1(gene name synonym)|uniprotkb:Rtn4r(gene name)|psi-mi:Rtn4r(display_short)|uniprotkb:Nogor(gene name synonym)|uniprotkb:Nogo receptor(gene name synonym)|uniprotkb:Nogo-66 receptor(gene name synonym)	psi-mi:rtn4_mouse(display_long)|uniprotkb:Rtn4(gene name)|psi-mi:Rtn4(display_short)|uniprotkb:Kiaa0886(gene name synonym)|uniprotkb:Nogo(gene name synonym)|uniprotkb:Neurite outgrowth inhibitor(gene name synonym)	psi-mi:"MI:0428"(imaging technique)	Fournier et al. (2001)	pubmed:11201742|mint:MINT-5213544	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7766133|mint:MINT-15771	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000043811(gene)|ensembl:ENSMUST00000059589(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008201"(heparin binding)|go:"GO:0009986"(cell surface)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0023041"(neuronal signal transduction)|go:"GO:0030426"(growth cone)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035374"(chondroitin sulfate binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0038131"(neuregulin receptor activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048495"(Roundabout binding)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905573"(ganglioside GM1 binding)|go:"GO:1905576"(ganglioside GT1b binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|mint:Q99PI8|rcsb pdb:5O0K|rcsb pdb:5O0L|rcsb pdb:5O0M|rcsb pdb:5O0N|rcsb pdb:5O0O|rcsb pdb:5O0Q|rcsb pdb:5O0R|rcsb pdb:5O0P|refseq:NP_075358.1|mint:MINT-468234(identity)	refseq:NP_077188.1|refseq:NP_918940.1|refseq:NP_918943.1|dip:DIP-41976N|ensembl:ENSMUSG00000020458(gene)|ensembl:ENSMUST00000102843(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007399"(nervous system development)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021801"(cerebral cortex radial glia-guided migration)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0033603"(positive regulation of dopamine secretion)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0035441"(cell migration involved in vasculogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045687"(positive regulation of glial cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0051960"(regulation of nervous system development)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0070571"(negative regulation of neuron projection regeneration)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0120078"(cell adhesion involved in sprouting angiogenesis)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902624"(positive regulation of neutrophil migration)|go:"GO:1905523"(positive regulation of macrophage migration)|go:"GO:1905552"(positive regulation of protein localization to endoplasmic reticulum)|go:"GO:1905580"(positive regulation of ERBB3 signaling pathway)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|go:"GO:2000172"(regulation of branching morphogenesis of a nerve)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001213"(negative regulation of vasculogenesis)|interpro:IPR003388(Reticulon)|mint:Q99P72|rcsb pdb:2KO2|reactome:R-MMU-193634|refseq:NP_918941.1|refseq:NP_918942.1|mint:MINT-468229(identity)	-	comment:mint|function:Receptor for RTN4, OMG and MAG. Mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2002/07/26	2014/10/16	rogid:TQ/XncSvF4z/pYDIDf7gNZk8b8010090	rogid:+hmGWVeJPIbs6/SavXBsKK22Nqw10090	intact-crc:3C76D38CE3B2FFB2|rigid:XVTQNVL2w26eRld1T/GuLPvZ8mc	false	-	binding-associated region:51-137(MINT-468230)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)