#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P52566	uniprotkb:P15153	intact:EBI-2806617|uniprotkb:B5BU79|ensembl:ENSP00000228945|ensembl:ENSP00000440560|ensembl:ENSP00000444860	intact:EBI-489652|ensembl:ENSP00000249071|uniprotkb:Q9UDJ4	psi-mi:gdir2_human(display_long)|uniprotkb:GDIA2(gene name synonym)|uniprotkb:GDID4(gene name synonym)|uniprotkb:RAP1GN1(gene name synonym)|uniprotkb:Ly-GDI(gene name synonym)|uniprotkb:Rho-GDI beta(gene name synonym)|uniprotkb:ARHGDIB(gene name)|psi-mi:ARHGDIB(display_short)	psi-mi:rac2_human(display_long)|uniprotkb:p21-Rac2(gene name synonym)|uniprotkb:Small G protein(gene name synonym)|uniprotkb:GX(gene name synonym)|uniprotkb:RAC2(gene name)|psi-mi:RAC2(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Scheffzek et al. (2000)	pubmed:10655614|mint:MINT-5212208	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7187112|mint:MINT-16596	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166.3|ensembl:ENSG00000111348(gene)|ensembl:ENST00000541546(transcript)|ensembl:ENST00000541644(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005094"(Rho GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071461"(cellular response to redox state)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|ensembl:ENST00000228945(transcript)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000406(RHO protein GDP dissociation inhibitor)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024792|mint:P52566|rcsb pdb:1DS6|rcsb pdb:5H1D|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013423|refseq:NP_001308349.1|refseq:NP_001308350.1|refseq:NP_001308351.1|refseq:NP_001308352.1|dip:DIP-40959N|mint:MINT-1616382(identity)	go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045453"(bone resorption)|go:"GO:0060263"(regulation of respiratory burst)|go:"GO:0060753"(regulation of mast cell chemotaxis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071593"(lymphocyte aggregation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902622"(regulation of neutrophil migration)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P15153|rcsb pdb:1DS6|rcsb pdb:2W2T|rcsb pdb:2W2V|rcsb pdb:2W2X|reactome:R-HSA-114604|reactome:R-HSA-1222556|go:"GO:0043304"(regulation of mast cell degranulation)|ensembl:ENSG00000128340(gene)|ensembl:ENST00000249071(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010810"(regulation of cell-substrate adhesion)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0005925"(focal adhesion)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|reactome:R-HSA-1257604|refseq:NP_002863.1|reactome:R-HSA-2219530|reactome:R-HSA-4086400|reactome:R-HSA-5668599|reactome:R-HSA-6811558|reactome:R-HSA-9013404|dip:DIP-34291N|mint:MINT-1616389(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:An inner segment of LyN forms a helical hairpin that contacts mainly the switch regions of Rac2.|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2002/04/27	2014/10/16	rogid:uiFgGyiT2vBDU0XIRX2ix/bDmHw9606	rogid:NYkPt/WNmKM3qAhhaufLCPkc/io9606	intact-crc:B69689396B858E8E|rigid:xQshQSuxstan8nkB+YOODBAjZlU	false	binding-associated region:1-74(MINT-1616383)	binding-associated region:161-192(MINT-1616390)	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P52566	uniprotkb:P15153	intact:EBI-2806617|uniprotkb:B5BU79|ensembl:ENSP00000228945|ensembl:ENSP00000440560|ensembl:ENSP00000444860	intact:EBI-489652|ensembl:ENSP00000249071|uniprotkb:Q9UDJ4	psi-mi:gdir2_human(display_long)|uniprotkb:GDIA2(gene name synonym)|uniprotkb:GDID4(gene name synonym)|uniprotkb:RAP1GN1(gene name synonym)|uniprotkb:Ly-GDI(gene name synonym)|uniprotkb:Rho-GDI beta(gene name synonym)|uniprotkb:ARHGDIB(gene name)|psi-mi:ARHGDIB(display_short)	psi-mi:rac2_human(display_long)|uniprotkb:p21-Rac2(gene name synonym)|uniprotkb:Small G protein(gene name synonym)|uniprotkb:GX(gene name synonym)|uniprotkb:RAC2(gene name)|psi-mi:RAC2(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Scheffzek et al. (2000)	pubmed:10655614|mint:MINT-5212208	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7187187|mint:MINT-24949	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166.3|ensembl:ENSG00000111348(gene)|ensembl:ENST00000541546(transcript)|ensembl:ENST00000541644(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005094"(Rho GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071461"(cellular response to redox state)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|ensembl:ENST00000228945(transcript)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000406(RHO protein GDP dissociation inhibitor)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024792|mint:P52566|rcsb pdb:1DS6|rcsb pdb:5H1D|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013423|refseq:NP_001308349.1|refseq:NP_001308350.1|refseq:NP_001308351.1|refseq:NP_001308352.1|dip:DIP-40959N|mint:MINT-1725517(identity)	go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045453"(bone resorption)|go:"GO:0060263"(regulation of respiratory burst)|go:"GO:0060753"(regulation of mast cell chemotaxis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071593"(lymphocyte aggregation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902622"(regulation of neutrophil migration)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P15153|rcsb pdb:1DS6|rcsb pdb:2W2T|rcsb pdb:2W2V|rcsb pdb:2W2X|reactome:R-HSA-114604|reactome:R-HSA-1222556|go:"GO:0043304"(regulation of mast cell degranulation)|ensembl:ENSG00000128340(gene)|ensembl:ENST00000249071(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010810"(regulation of cell-substrate adhesion)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0005925"(focal adhesion)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|reactome:R-HSA-1257604|refseq:NP_002863.1|reactome:R-HSA-2219530|reactome:R-HSA-4086400|reactome:R-HSA-5668599|reactome:R-HSA-6811558|reactome:R-HSA-9013404|dip:DIP-34291N|mint:MINT-1725510(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:In the xray complex 1ds6, P15153 is chain A and P52566 is chain B Resolution 2.350|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2002/04/27	2014/10/16	rogid:uiFgGyiT2vBDU0XIRX2ix/bDmHw9606	rogid:NYkPt/WNmKM3qAhhaufLCPkc/io9606	intact-crc:7CD8E57268A92FDB|rigid:xQshQSuxstan8nkB+YOODBAjZlU	false	tag:?-?(MINT-1725518)	tag:?-?(MINT-1725511)	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)