#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8NFH8	uniprotkb:Q62796	intact:EBI-7067016|ensembl:ENSP00000349824|uniprotkb:Q5JNZ8|intact:MINT-110628|uniprotkb:O43428|uniprotkb:Q8NFI5|uniprotkb:A6PWZ6	intact:EBI-3956409|uniprotkb:O55195	psi-mi:reps2_human(display_long)|uniprotkb:REPS2(gene name)|psi-mi:REPS2(display_short)|uniprotkb:POB1(gene name synonym)|uniprotkb:RalBP1-interacting protein 2(gene name synonym)|uniprotkb:Partner of RalBP1(gene name synonym)	psi-mi:rbp1_rat(display_long)|uniprotkb:Ralbp1(gene name)|psi-mi:Ralbp1(display_short)|uniprotkb:Cytocentrin(gene name synonym)|uniprotkb:Dinitrophenyl S-glutathione ATPase(gene name synonym)|uniprotkb:Ral-interacting protein 1(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Ikeda et al. (1998)	mint:MINT-5221840|pubmed:9422736	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8673733|mint:MINT-17935	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000169891(gene)|ensembl:ENST00000357277(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q8NFH8|rcsb pdb:1IQ3|reactome:R-HSA-8856825|reactome:R-HSA-8856828|refseq:NP_001074444.1|refseq:NP_004717.2|mint:MINT-1530373(identity)	interpro:IPR039767|go:"GO:1900753"(doxorubicin transport)|go:"GO:1903378"(positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0000922"(spindle pole)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0051301"(cell division)|go:"GO:0055085"(transmembrane transport)|rgd:621134|refseq:NP_114456.1|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|reactome:R-RNO-9013148|reactome:R-RNO-9013149|mint:MINT-1530378(identity)	-	comment:mint|function:Involved in growth factor signaling through its influence on the Ral signaling pathway|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/02/01	2014/10/16	rogid:uOae9UghyyHGiFmm3gpLBE/Ay8Y9606	rogid:lAaw4kuTmCMmQr7mthjWin7HsW410116	intact-crc:A769F9D1F0A5AC92|rigid:+DhBf2/8Bz93lO/pCCVkhV6GKfk	false	binding-associated region:375-521(MINT-1530374)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NFH8	uniprotkb:Q62796	intact:EBI-7067016|ensembl:ENSP00000349824|uniprotkb:Q5JNZ8|intact:MINT-110628|uniprotkb:O43428|uniprotkb:Q8NFI5|uniprotkb:A6PWZ6	intact:EBI-3956409|uniprotkb:O55195	psi-mi:reps2_human(display_long)|uniprotkb:REPS2(gene name)|psi-mi:REPS2(display_short)|uniprotkb:POB1(gene name synonym)|uniprotkb:RalBP1-interacting protein 2(gene name synonym)|uniprotkb:Partner of RalBP1(gene name synonym)	psi-mi:rbp1_rat(display_long)|uniprotkb:Ralbp1(gene name)|psi-mi:Ralbp1(display_short)|uniprotkb:Cytocentrin(gene name synonym)|uniprotkb:Dinitrophenyl S-glutathione ATPase(gene name synonym)|uniprotkb:Ral-interacting protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Ikeda et al. (1998)	mint:MINT-5221840|pubmed:9422736	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8673772|mint:MINT-17934	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000169891(gene)|ensembl:ENST00000357277(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q8NFH8|rcsb pdb:1IQ3|reactome:R-HSA-8856825|reactome:R-HSA-8856828|refseq:NP_001074444.1|refseq:NP_004717.2|mint:MINT-1530386(identity)	interpro:IPR039767|go:"GO:1900753"(doxorubicin transport)|go:"GO:1903378"(positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0000922"(spindle pole)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0051301"(cell division)|go:"GO:0055085"(transmembrane transport)|rgd:621134|refseq:NP_114456.1|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|reactome:R-RNO-9013148|reactome:R-RNO-9013149|mint:MINT-1530394(identity)	-	comment:mint|function:Involved in growth factor signaling through its influence on the Ral signaling pathway|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/02/01	2014/10/16	rogid:uOae9UghyyHGiFmm3gpLBE/Ay8Y9606	rogid:lAaw4kuTmCMmQr7mthjWin7HsW410116	intact-crc:20B652259A9C1D1E|rigid:+DhBf2/8Bz93lO/pCCVkhV6GKfk	false	tag:?-?(MINT-1530389)|binding-associated region:375-521(MINT-1530387)	tag:?-?(MINT-1530395)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NFH8	uniprotkb:Q9Y6I3	intact:EBI-7067016|ensembl:ENSP00000349824|uniprotkb:Q5JNZ8|intact:MINT-110628|uniprotkb:O43428|uniprotkb:Q8NFI5|uniprotkb:A6PWZ6	intact:EBI-713198|intact:EBI-28967658|ensembl:ENSP00000270460|uniprotkb:Q86ST3|uniprotkb:Q9HA18	psi-mi:reps2_human(display_long)|uniprotkb:REPS2(gene name)|psi-mi:REPS2(display_short)|uniprotkb:POB1(gene name synonym)|uniprotkb:RalBP1-interacting protein 2(gene name synonym)|uniprotkb:Partner of RalBP1(gene name synonym)	psi-mi:epn1_human(display_long)|uniprotkb:EPS-15-interacting protein 1(gene name synonym)|uniprotkb:EH domain-binding mitotic phosphoprotein(gene name synonym)|uniprotkb:EPN1(gene name)|psi-mi:EPN1(display_short)	psi-mi:"MI:0096"(pull down)	Ikeda et al. (1998)	mint:MINT-5221840|pubmed:9422736	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8673800|mint:MINT-19262	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000169891(gene)|ensembl:ENST00000357277(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q8NFH8|rcsb pdb:1IQ3|reactome:R-HSA-8856825|reactome:R-HSA-8856828|refseq:NP_001074444.1|refseq:NP_004717.2|mint:MINT-1530405(identity)	go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007565"(female pregnancy)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048568"(embryonic organ development)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|mint:Q9Y6I3|rcsb pdb:1INZ|rcsb pdb:1KYD|reactome:R-HSA-182971|reactome:R-HSA-8856825|reactome:R-HSA-8856828|ensembl:ENSG00000063245(gene)|ensembl:ENST00000270460(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|ensembl:ENST00000085079|ensembl:ENSP00000085079|ensembl:ENSP00000270460|ensembl:ENST00000411543|ensembl:ENSP00000406209|refseq:NP_001123543.1|refseq:NP_001123544.1|refseq:NP_037465.2|refseq:XP_005258886.1|refseq:XP_016882211.1|refseq:XP_011525183.1|mint:MINT-1530411(identity)	-	comment:mint|function:Involved in growth factor signaling through its influence on the Ral signaling pathway|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2001/02/01	2014/10/16	rogid:uOae9UghyyHGiFmm3gpLBE/Ay8Y9606	rogid:mp6MIJYGUJryy3Lk5coFqvOt55c9606	intact-crc:98C4689EC0C4BF93|rigid:SfAu8P5c1ejlyo+UUWQ6bSTqyJs	false	binding-associated region:126-227(MINT-1530406)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)