#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P62999 uniprotkb:Q9VF87 intact:EBI-7002659|ensembl:ENSCAFP00030028596|ensembl:ENSCAFP00040022379|uniprotkb:O95501|uniprotkb:Q9BTB4|uniprotkb:P15154|intact:MINT-93844 intact:EBI-116862|uniprotkb:Q6NP16|uniprotkb:Q8MR06|ensemblmetazoa:FBpp0082541 psi-mi:rac1_canlf(display_long)|uniprotkb:RAC1(gene name)|psi-mi:RAC1(display_short)|uniprotkb:p21-Rac1(gene name synonym)|uniprotkb:Rac2(gene name synonym) psi-mi:cyfip_drome(display_long)|uniprotkb:Sra-1(gene name)|psi-mi:Sra-1(display_short)|uniprotkb:Cyfip(gene name synonym)|uniprotkb:CG4931(orf name)|uniprotkb:Specifically Rac1-associated protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Kobayashi et al. (1998) mint:MINT-5221825|pubmed:9417078 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8671076|mint:MINT-15684 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00030017683(gene)|ensembl:ENSCAFG00040013856(gene)|ensembl:ENSCAFT00030032776(transcript)|ensembl:ENSCAFT00040025732(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016020"(membrane)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0048870"(cell motility)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1902622"(regulation of neutrophil migration)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|reactome:R-CFA-389359|reactome:R-CFA-3928662|reactome:R-CFA-3928664|reactome:R-CFA-3928665|reactome:R-CFA-399954|reactome:R-CFA-4086400|reactome:R-CFA-418885|reactome:R-CFA-4420097|reactome:R-CFA-445144|reactome:R-CFA-5218920|reactome:R-CFA-5625740|reactome:R-CFA-5625900|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-CFA-114604|reactome:R-CFA-1257604|reactome:R-CFA-1433557|reactome:R-CFA-193648|reactome:R-CFA-2029482|reactome:R-CFA-2424491|reactome:R-CFA-2871796|reactome:R-CFA-376172|reactome:R-CFA-5625970|reactome:R-CFA-5626467|reactome:R-CFA-5627123|reactome:R-CFA-5663213|reactome:R-CFA-5663220|reactome:R-CFA-5668599|reactome:R-CFA-5687128|reactome:R-CFA-6798695|reactome:R-CFA-6811558|reactome:R-CFA-8849471|reactome:R-CFA-8875555|reactome:R-CFA-9013149|reactome:R-CFA-9032759|reactome:R-CFA-983231|refseq:NP_001003274.1|dip:DIP-40906N|mint:MINT-1530080(identity) ensemblmetazoa:FBgn0038320(gene)|ensemblmetazoa:FBtr0083085(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0007411"(axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0022416"(chaeta development)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0043005"(neuron projection)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060269"(centripetally migrating follicle cell migration)|interpro:IPR008081(Cytoplasmic FMR1-interacting)|interpro:IPR009828(Protein of unknown function DUF1394)|reactome:R-DME-2029482|reactome:R-DME-4420097|reactome:R-DME-5663213|reactome:R-DME-6798695|reactome:R-DME-9013149|reactome:R-DME-9013404|go:"GO:0031209"(SCAR complex)|refseq:NP_650447.1|flybase:FBgn0038320|dip:DIP-33370N|mint:MINT-1530083(identity) - comment:mint|function:Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization and growth-factor induced formation of membrane ruffles|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2001/12/23 2014/10/16 rogid:8rkYyZSFL5tIfbRNKZgP/UDxD+A9615 rogid:wgefW/1I4r4WR1sDFpe3VKR80+o7227 intact-crc:7784303AA0FD0CF4|rigid:RQMdAqu+9HvTTXqHG7XbKBR/ZjQ false - binding-associated region:1-407(MINT-1530084) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P60706 uniprotkb:Q9VF87 intact:EBI-8297650|intact:MINT-199239|uniprotkb:P70514|uniprotkb:Q11211|uniprotkb:P99021|uniprotkb:P02570|uniprotkb:Q64316|ensembl:ENSGALP00000015657|ensembl:ENSGALP00000060844 intact:EBI-116862|uniprotkb:Q6NP16|uniprotkb:Q8MR06|ensemblmetazoa:FBpp0082541 psi-mi:actb_chick(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:cyfip_drome(display_long)|uniprotkb:Sra-1(gene name)|psi-mi:Sra-1(display_short)|uniprotkb:Cyfip(gene name synonym)|uniprotkb:CG4931(orf name)|uniprotkb:Specifically Rac1-associated protein 1(gene name synonym) psi-mi:"MI:0428"(imaging technique) Kobayashi et al. (1998) mint:MINT-5221825|pubmed:9417078 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8671184|mint:MINT-14450 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_990849.1|dip:DIP-41284N|ensembl:ENSGALG00000009621(gene)|ensembl:ENSGALT00000015673(transcript)|ensembl:ENSGALT00000089197(transcript)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0070160"(tight junction)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:3J0S|reactome:R-GGA-190873|reactome:R-GGA-196025|reactome:R-GGA-2029482|reactome:R-GGA-3928662|reactome:R-GGA-3928665|reactome:R-GGA-418990|reactome:R-GGA-437239|reactome:R-GGA-4420097|reactome:R-GGA-5626467|reactome:R-GGA-5663213|reactome:R-GGA-5663220|reactome:R-GGA-5674135|reactome:R-GGA-5689603|reactome:R-GGA-5696394|reactome:R-GGA-8856828|reactome:R-GGA-9035034|mint:MINT-1530115(identity) ensemblmetazoa:FBgn0038320(gene)|ensemblmetazoa:FBtr0083085(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0007411"(axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0022416"(chaeta development)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0043005"(neuron projection)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060269"(centripetally migrating follicle cell migration)|interpro:IPR008081(Cytoplasmic FMR1-interacting)|interpro:IPR009828(Protein of unknown function DUF1394)|reactome:R-DME-2029482|reactome:R-DME-4420097|reactome:R-DME-5663213|reactome:R-DME-6798695|reactome:R-DME-9013149|reactome:R-DME-9013404|go:"GO:0031209"(SCAR complex)|refseq:NP_650447.1|flybase:FBgn0038320|dip:DIP-33370N|mint:MINT-1530112(identity) - comment:mint|function:Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:mint taxid:-4(in vivo)|taxid:-4(in vivo) - 2001/12/23 2014/10/16 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9031 rogid:wgefW/1I4r4WR1sDFpe3VKR80+o7227 intact-crc:761B280F9DA0F35B|rigid:4RE/5FsOMVLt4Sk8nM++G8sDwuk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62999 uniprotkb:Q9VF87 intact:EBI-7002659|ensembl:ENSCAFP00030028596|ensembl:ENSCAFP00040022379|uniprotkb:O95501|uniprotkb:Q9BTB4|uniprotkb:P15154|intact:MINT-93844 intact:EBI-116862|uniprotkb:Q6NP16|uniprotkb:Q8MR06|ensemblmetazoa:FBpp0082541 psi-mi:rac1_canlf(display_long)|uniprotkb:RAC1(gene name)|psi-mi:RAC1(display_short)|uniprotkb:p21-Rac1(gene name synonym)|uniprotkb:Rac2(gene name synonym) psi-mi:cyfip_drome(display_long)|uniprotkb:Sra-1(gene name)|psi-mi:Sra-1(display_short)|uniprotkb:Cyfip(gene name synonym)|uniprotkb:CG4931(orf name)|uniprotkb:Specifically Rac1-associated protein 1(gene name synonym) psi-mi:"MI:0428"(imaging technique) Kobayashi et al. (1998) mint:MINT-5221825|pubmed:9417078 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8671132|mint:MINT-15683 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00030017683(gene)|ensembl:ENSCAFG00040013856(gene)|ensembl:ENSCAFT00030032776(transcript)|ensembl:ENSCAFT00040025732(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016020"(membrane)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0048870"(cell motility)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1902622"(regulation of neutrophil migration)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|reactome:R-CFA-389359|reactome:R-CFA-3928662|reactome:R-CFA-3928664|reactome:R-CFA-3928665|reactome:R-CFA-399954|reactome:R-CFA-4086400|reactome:R-CFA-418885|reactome:R-CFA-4420097|reactome:R-CFA-445144|reactome:R-CFA-5218920|reactome:R-CFA-5625740|reactome:R-CFA-5625900|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-CFA-114604|reactome:R-CFA-1257604|reactome:R-CFA-1433557|reactome:R-CFA-193648|reactome:R-CFA-2029482|reactome:R-CFA-2424491|reactome:R-CFA-2871796|reactome:R-CFA-376172|reactome:R-CFA-5625970|reactome:R-CFA-5626467|reactome:R-CFA-5627123|reactome:R-CFA-5663213|reactome:R-CFA-5663220|reactome:R-CFA-5668599|reactome:R-CFA-5687128|reactome:R-CFA-6798695|reactome:R-CFA-6811558|reactome:R-CFA-8849471|reactome:R-CFA-8875555|reactome:R-CFA-9013149|reactome:R-CFA-9032759|reactome:R-CFA-983231|refseq:NP_001003274.1|dip:DIP-40906N|mint:MINT-1530120(identity) ensemblmetazoa:FBgn0038320(gene)|ensemblmetazoa:FBtr0083085(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0007411"(axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0022416"(chaeta development)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0043005"(neuron projection)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060269"(centripetally migrating follicle cell migration)|interpro:IPR008081(Cytoplasmic FMR1-interacting)|interpro:IPR009828(Protein of unknown function DUF1394)|reactome:R-DME-2029482|reactome:R-DME-4420097|reactome:R-DME-5663213|reactome:R-DME-6798695|reactome:R-DME-9013149|reactome:R-DME-9013404|go:"GO:0031209"(SCAR complex)|refseq:NP_650447.1|flybase:FBgn0038320|dip:DIP-33370N|mint:MINT-1530123(identity) - comment:mint|function:Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization and growth-factor induced formation of membrane ruffles|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:homomint|comment:mint taxid:-4(in vivo)|taxid:-4(in vivo) - 2001/12/23 2014/10/16 rogid:8rkYyZSFL5tIfbRNKZgP/UDxD+A9615 rogid:wgefW/1I4r4WR1sDFpe3VKR80+o7227 intact-crc:48CC36B5C41B98B2|rigid:RQMdAqu+9HvTTXqHG7XbKBR/ZjQ false - binding-associated region:1-407(MINT-1530124) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62999 uniprotkb:P55161 intact:EBI-7002659|ensembl:ENSCAFP00030028596|ensembl:ENSCAFP00040022379|uniprotkb:O95501|uniprotkb:Q9BTB4|uniprotkb:P15154|intact:MINT-93844 intact:EBI-917798 psi-mi:rac1_canlf(display_long)|uniprotkb:RAC1(gene name)|psi-mi:RAC1(display_short)|uniprotkb:p21-Rac1(gene name synonym)|uniprotkb:Rac2(gene name synonym) psi-mi:nckp1_rat(display_long)|uniprotkb:p125Nap1(gene name synonym)|uniprotkb:Membrane-associated protein HEM-2(gene name synonym)|uniprotkb:Nckap1(gene name)|psi-mi:Nckap1(display_short)|uniprotkb:Hem2(gene name synonym)|uniprotkb:Nap1(gene name synonym) psi-mi:"MI:0428"(imaging technique) Kobayashi et al. (1998) mint:MINT-5221825|pubmed:9417078 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8671174|mint:MINT-17742 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00030017683(gene)|ensembl:ENSCAFG00040013856(gene)|ensembl:ENSCAFT00030032776(transcript)|ensembl:ENSCAFT00040025732(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016020"(membrane)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0048870"(cell motility)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1902622"(regulation of neutrophil migration)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|reactome:R-CFA-389359|reactome:R-CFA-3928662|reactome:R-CFA-3928664|reactome:R-CFA-3928665|reactome:R-CFA-399954|reactome:R-CFA-4086400|reactome:R-CFA-418885|reactome:R-CFA-4420097|reactome:R-CFA-445144|reactome:R-CFA-5218920|reactome:R-CFA-5625740|reactome:R-CFA-5625900|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-CFA-114604|reactome:R-CFA-1257604|reactome:R-CFA-1433557|reactome:R-CFA-193648|reactome:R-CFA-2029482|reactome:R-CFA-2424491|reactome:R-CFA-2871796|reactome:R-CFA-376172|reactome:R-CFA-5625970|reactome:R-CFA-5626467|reactome:R-CFA-5627123|reactome:R-CFA-5663213|reactome:R-CFA-5663220|reactome:R-CFA-5668599|reactome:R-CFA-5687128|reactome:R-CFA-6798695|reactome:R-CFA-6811558|reactome:R-CFA-8849471|reactome:R-CFA-8875555|reactome:R-CFA-9013149|reactome:R-CFA-9032759|reactome:R-CFA-983231|refseq:NP_001003274.1|dip:DIP-40906N|mint:MINT-1530104(identity) interpro:IPR019137|rgd:61939|refseq:NP_113806.1|reactome:R-RNO-9013149|reactome:R-RNO-9013404|reactome:R-RNO-9013423|reactome:R-RNO-2029482|reactome:R-RNO-4420097|reactome:R-RNO-5663213|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030903"(notochord development)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031209"(SCAR complex)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031941"(filamentous actin)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0045175"(basal protein localization)|go:"GO:0045176"(apical protein localization)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048340"(paraxial mesoderm morphogenesis)|go:"GO:0048570"(notochord morphogenesis)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0098794"(postsynapse)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001726"(ruffle)|go:"GO:0001756"(somitogenesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0007354"(zygotic determination of anterior/posterior axis, embryo)|go:"GO:0007492"(endoderm development)|go:"GO:0008078"(mesodermal cell migration)|mint:MINT-1530107(identity) - comment:mint|function:Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization and growth-factor induced formation of membrane ruffles|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:homomint|comment:mint taxid:-4(in vivo)|taxid:-4(in vivo) - 2001/12/23 2014/10/16 rogid:8rkYyZSFL5tIfbRNKZgP/UDxD+A9615 rogid:STo4DC5yxeuoNC9SSGUJLVMmK4I10116 intact-crc:856315E7E99F7558|rigid:SkKXF7rzStjvkDqIVIIOry1Jjv4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)