#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P28028	uniprotkb:P63102	intact:EBI-2584830|uniprotkb:E9QNG9|uniprotkb:Q3USE9|uniprotkb:F6SZ47	intact:EBI-354758|uniprotkb:P35215|uniprotkb:P70197|uniprotkb:P97286|uniprotkb:Q52KK1|uniprotkb:Q6IRF4|ensembl:ENSRNOP00000030885	psi-mi:braf_mouse(display_long)|uniprotkb:Braf(gene name)|psi-mi:Braf(display_short)|uniprotkb:B-raf(gene name synonym)|uniprotkb:Proto-oncogene B-Raf(gene name synonym)	psi-mi:1433z_rat(display_long)|uniprotkb:Ywhaz(gene name)|psi-mi:Ywhaz(display_short)|uniprotkb:Msfs1(gene name synonym)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Mitochondrial import stimulation factor S1 subunit(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Papin et al. (1996)	mint:MINT-5221085|pubmed:8668348	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8683514|mint:MINT-17673	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_647455.3|go:"GO:0043367"(CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043368"(positive T cell selection)|go:"GO:0043369"(CD4-positive or CD8-positive, alpha-beta T cell lineage commitment)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0048538"(thymus development)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051591"(response to cAMP)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060323"(head morphogenesis)|go:"GO:0060324"(face development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:2000301"(negative regulation of synaptic vesicle exocytosis)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0070413"(trehalose metabolism in response to stress)|interpro:IPR001245(Tyrosine protein kinase)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR003116(Raf-like Ras-binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020454|interpro:IPR029071|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0002318"(myeloid progenitor cell differentiation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0008542"(visual learning)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010764"(negative regulation of fibroblast migration)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035690"|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|reactome:R-MMU-1295596|reactome:R-MMU-5673000|reactome:R-MMU-5674135|reactome:R-MMU-5674499|reactome:R-MMU-5675221|dip:DIP-57050N|reactome:R-MMU-170968|mint:MINT-1518202(identity)	rgd:3980|refseq:NP_037143.2|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031252"(cell leading edge)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035148"(tube formation)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P63102|reactome:R-RNO-111447|reactome:R-RNO-3769402|reactome:R-RNO-392517|reactome:R-RNO-430116|reactome:R-RNO-450604|reactome:R-RNO-512988|reactome:R-RNO-5625740|reactome:R-RNO-5628897|reactome:R-RNO-75035|reactome:R-RNO-9013700|reactome:R-RNO-9614399|refseq:XP_006241591.1|ensembl:ENSRNOG00000008195(gene)|ensembl:ENSRNOT00000035628(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002553"(histamine secretion by mast cell)|go:"GO:0003016"(respiratory system process)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|dip:DIP-36916N|mint:MINT-1518208(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/02/02	2021/02/11	rogid:EblhyDWxW1SHryfZ0Jlabs2rCuw10090	rogid:v2N95HO8sYRWEg2gFtWiYajP1Sc10116	intact-crc:7D11E293BA84904C|rigid:ZZS8IYNT8ybGAsgmi8a5s4Vo0sk	false	tag:?-?(MINT-1518203)	tag:?-?(MINT-1518212)|binding-associated region:1-245(MINT-1518209)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P28028	uniprotkb:P68510	intact:EBI-2584830|uniprotkb:E9QNG9|uniprotkb:Q3USE9|uniprotkb:F6SZ47	intact:EBI-444641|uniprotkb:P11576|uniprotkb:P70198|uniprotkb:Q3TGZ9|ensembl:ENSMUSP00000019109	psi-mi:braf_mouse(display_long)|uniprotkb:Braf(gene name)|psi-mi:Braf(display_short)|uniprotkb:B-raf(gene name synonym)|uniprotkb:Proto-oncogene B-Raf(gene name synonym)	psi-mi:1433f_mouse(display_long)|uniprotkb:Ywhah(gene name)|psi-mi:Ywhah(display_short)	psi-mi:"MI:0018"(two hybrid)	Papin et al. (1996)	mint:MINT-5221085|pubmed:8668348	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8683498|mint:MINT-15687	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_647455.3|go:"GO:0043367"(CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043368"(positive T cell selection)|go:"GO:0043369"(CD4-positive or CD8-positive, alpha-beta T cell lineage commitment)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0048538"(thymus development)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051591"(response to cAMP)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060323"(head morphogenesis)|go:"GO:0060324"(face development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:2000301"(negative regulation of synaptic vesicle exocytosis)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0070413"(trehalose metabolism in response to stress)|interpro:IPR001245(Tyrosine protein kinase)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR003116(Raf-like Ras-binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020454|interpro:IPR029071|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0002318"(myeloid progenitor cell differentiation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0008542"(visual learning)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010764"(negative regulation of fibroblast migration)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035690"|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|reactome:R-MMU-1295596|reactome:R-MMU-5673000|reactome:R-MMU-5674135|reactome:R-MMU-5674499|reactome:R-MMU-5675221|dip:DIP-57050N|reactome:R-MMU-170968|mint:MINT-1518187(identity)	refseq:NP_035868.1|ensembl:ENSMUSG00000018965(gene)|ensembl:ENSMUST00000019109(transcript)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006713"(glucocorticoid catabolic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0014704"(intercalated disc)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P68510|rcsb pdb:5YQG|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-111447|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|mint:MINT-1518193(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/02/02	2021/02/11	rogid:EblhyDWxW1SHryfZ0Jlabs2rCuw10090	rogid:Ew2uUYIXrZ8nnP52xMnGB6KOCqc10090	intact-crc:7CA1A354248EF579|rigid:u+gyWVrescnjD6ihOL4fDUoLj64	false	tag:?-?(MINT-1518188)	tag:?-?(MINT-1518194)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P28028	uniprotkb:P68255	intact:EBI-2584830|uniprotkb:E9QNG9|uniprotkb:Q3USE9|uniprotkb:F6SZ47	intact:EBI-400680|uniprotkb:P35216|ensembl:ENSRNOP00000072011	psi-mi:braf_mouse(display_long)|uniprotkb:Braf(gene name)|psi-mi:Braf(display_short)|uniprotkb:B-raf(gene name synonym)|uniprotkb:Proto-oncogene B-Raf(gene name synonym)	psi-mi:1433t_rat(display_long)|uniprotkb:Ywhaq(gene name)|psi-mi:Ywhaq(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Papin et al. (1996)	mint:MINT-5221085|pubmed:8668348	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8683534|mint:MINT-14614	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_647455.3|go:"GO:0043367"(CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043368"(positive T cell selection)|go:"GO:0043369"(CD4-positive or CD8-positive, alpha-beta T cell lineage commitment)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0048538"(thymus development)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051591"(response to cAMP)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060323"(head morphogenesis)|go:"GO:0060324"(face development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:2000301"(negative regulation of synaptic vesicle exocytosis)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0070413"(trehalose metabolism in response to stress)|interpro:IPR001245(Tyrosine protein kinase)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR003116(Raf-like Ras-binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020454|interpro:IPR029071|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0002318"(myeloid progenitor cell differentiation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0008542"(visual learning)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010764"(negative regulation of fibroblast migration)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035690"|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|reactome:R-MMU-1295596|reactome:R-MMU-5673000|reactome:R-MMU-5674135|reactome:R-MMU-5674499|reactome:R-MMU-5675221|dip:DIP-57050N|reactome:R-MMU-170968|mint:MINT-1518219(identity)	rgd:3979|refseq:NP_037185.1|ensembl:ENSRNOG00000051650(gene)|ensembl:ENSRNOT00000077786(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006605"(protein targeting)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034766"(negative regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071889"(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P68255|reactome:R-RNO-111447|reactome:R-RNO-5625740|reactome:R-RNO-5628897|reactome:R-RNO-75035|reactome:R-RNO-9614399|dip:DIP-947N|mint:MINT-1518225(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/02/02	2021/02/11	rogid:EblhyDWxW1SHryfZ0Jlabs2rCuw10090	rogid:l8bki6QJJEH5S5NIwQdm/MAYcc010116	intact-crc:B534F263AA517ECE|rigid:9O5wmXHmbc2dRiWtZZf7Eibze+g	false	tag:?-?(MINT-1518220)	tag:?-?(MINT-1518226)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P28028	uniprotkb:Q61411	intact:EBI-2584830|uniprotkb:E9QNG9|uniprotkb:Q3USE9|uniprotkb:F6SZ47	intact:EBI-400273|uniprotkb:Q80WD2|uniprotkb:Q6P716|uniprotkb:Q811B9|ensembl:ENSMUSP00000026572|ensembl:ENSMUSP00000095570|uniprotkb:F7BIB2	psi-mi:braf_mouse(display_long)|uniprotkb:Braf(gene name)|psi-mi:Braf(display_short)|uniprotkb:B-raf(gene name synonym)|uniprotkb:Proto-oncogene B-Raf(gene name synonym)	psi-mi:rash_mouse(display_long)|uniprotkb:Hras(gene name)|psi-mi:Hras(display_short)|uniprotkb:H-Ras-1(gene name synonym)|uniprotkb:Hras1(gene name synonym)|uniprotkb:Transforming protein p21(gene name synonym)|uniprotkb:c-H-ras(gene name synonym)|uniprotkb:p21ras(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Papin et al. (1996)	mint:MINT-5221085|pubmed:8668348	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8683565|mint:MINT-17754	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_647455.3|go:"GO:0043367"(CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043368"(positive T cell selection)|go:"GO:0043369"(CD4-positive or CD8-positive, alpha-beta T cell lineage commitment)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0048538"(thymus development)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051591"(response to cAMP)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060323"(head morphogenesis)|go:"GO:0060324"(face development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:2000301"(negative regulation of synaptic vesicle exocytosis)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0070413"(trehalose metabolism in response to stress)|interpro:IPR001245(Tyrosine protein kinase)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR003116(Raf-like Ras-binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020454|interpro:IPR029071|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0002318"(myeloid progenitor cell differentiation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0008542"(visual learning)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010764"(negative regulation of fibroblast migration)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035690"|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|reactome:R-MMU-1295596|reactome:R-MMU-5673000|reactome:R-MMU-5674135|reactome:R-MMU-5674499|reactome:R-MMU-5675221|dip:DIP-57050N|reactome:R-MMU-170968|mint:MINT-1518261(identity)	refseq:NP_001123915.1|refseq:NP_001123916.1|refseq:NP_032310.2|ensembl:ENSMUSG00000025499(gene)|ensembl:ENSMUST00000026572(transcript)|ensembl:ENSMUST00000097957(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007569"(cell aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0019003"(GDP binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035900"(response to isolation stress)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0090398"(cellular senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|mint:Q61411|rcsb pdb:6KYH|reactome:R-MMU-1169092|reactome:R-MMU-1250347|reactome:R-MMU-1433557|reactome:R-MMU-171007|reactome:R-MMU-179812|reactome:R-MMU-180336|reactome:R-MMU-186763|reactome:R-MMU-1963640|go:"GO:1900029"(positive regulation of ruffle assembly)|reactome:R-MMU-210993|reactome:R-MMU-2179392|reactome:R-MMU-2424491|reactome:R-MMU-2871796|reactome:R-MMU-375165|reactome:R-MMU-3928662|reactome:R-MMU-5218921|reactome:R-MMU-5621575|reactome:R-MMU-5654688|reactome:R-MMU-5654693|reactome:R-MMU-5654699|reactome:R-MMU-5654700|reactome:R-MMU-5654704|reactome:R-MMU-5654706|reactome:R-MMU-5654712|reactome:R-MMU-5654719|reactome:R-MMU-5658442|reactome:R-MMU-5673000|reactome:R-MMU-5673001|reactome:R-MMU-5674135|reactome:R-MMU-5675221|reactome:R-MMU-8849471|reactome:R-MMU-8851805|reactome:R-MMU-9607240|reactome:R-MMU-9634635|reactome:R-MMU-9648002|refseq:XP_006536222.2|dip:DIP-29361N|mint:MINT-1518267(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/02/02	2021/02/11	rogid:EblhyDWxW1SHryfZ0Jlabs2rCuw10090	rogid:hjBAnRVG6bLFePkCYnkl3ZCjnmw10090	intact-crc:F1F120C49E1631EE|rigid:Abw8D1mEcJSNAhFM7LmDqnuAZKs	false	tag:?-?(MINT-1518262)	tag:?-?(MINT-1518268)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P31938	uniprotkb:P28028	intact:EBI-298860|ensembl:ENSMUSP00000005066	intact:EBI-2584830|uniprotkb:E9QNG9|uniprotkb:Q3USE9|uniprotkb:F6SZ47	psi-mi:mp2k1_mouse(display_long)|uniprotkb:Map2k1(gene name)|psi-mi:Map2k1(display_short)|uniprotkb:Mek1(gene name synonym)|uniprotkb:Prkmk1(gene name synonym)|uniprotkb:ERK activator kinase 1(gene name synonym)|uniprotkb:MAPK/ERK kinase 1(gene name synonym)	psi-mi:braf_mouse(display_long)|uniprotkb:Braf(gene name)|psi-mi:Braf(display_short)|uniprotkb:B-raf(gene name synonym)|uniprotkb:Proto-oncogene B-Raf(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Papin et al. (1996)	mint:MINT-5221085|pubmed:8668348	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8683549|mint:MINT-16657	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000004936(gene)|ensembl:ENSMUST00000005066(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003056"(regulation of vascular associated smooth muscle contraction)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043204"(perikaryon)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032402"(melanosome transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034111"(negative regulation of homotypic cell-cell adhesion)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048313"(Golgi inheritance)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048538"(thymus development)|go:"GO:0048678"(response to axon injury)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0060502"(epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0090398"(cellular senescence)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-MMU-110056|reactome:R-MMU-170968|reactome:R-MMU-445144|reactome:R-MMU-5673000|reactome:R-MMU-5674135|reactome:R-MMU-5674499|refseq:NP_032953.1|dip:DIP-467N|mint:MINT-1518253(identity)	refseq:NP_647455.3|go:"GO:0043367"(CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043368"(positive T cell selection)|go:"GO:0043369"(CD4-positive or CD8-positive, alpha-beta T cell lineage commitment)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0048538"(thymus development)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051591"(response to cAMP)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060323"(head morphogenesis)|go:"GO:0060324"(face development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:2000301"(negative regulation of synaptic vesicle exocytosis)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0070413"(trehalose metabolism in response to stress)|interpro:IPR001245(Tyrosine protein kinase)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR003116(Raf-like Ras-binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020454|interpro:IPR029071|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0002318"(myeloid progenitor cell differentiation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0008542"(visual learning)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010764"(negative regulation of fibroblast migration)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035690"|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|reactome:R-MMU-1295596|reactome:R-MMU-5673000|reactome:R-MMU-5674135|reactome:R-MMU-5674499|reactome:R-MMU-5675221|dip:DIP-57050N|reactome:R-MMU-170968|mint:MINT-1518247(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/02/02	2021/02/11	rogid:OOj1juW9l4rnEH/W3CjXWZFKMvw10090	rogid:EblhyDWxW1SHryfZ0Jlabs2rCuw10090	intact-crc:C56D0961B334182E|rigid:1CGdhYrljOQj7oad3i3B13NSsuo	false	tag:?-?(MINT-1518254)	tag:?-?(MINT-1518248)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P28028	uniprotkb:Q63932	intact:EBI-2584830|uniprotkb:E9QNG9|uniprotkb:Q3USE9|uniprotkb:F6SZ47	intact:EBI-397724|ensembl:ENSMUSP00000121111|uniprotkb:Q9D7B0	psi-mi:braf_mouse(display_long)|uniprotkb:Braf(gene name)|psi-mi:Braf(display_short)|uniprotkb:B-raf(gene name synonym)|uniprotkb:Proto-oncogene B-Raf(gene name synonym)	psi-mi:mp2k2_mouse(display_long)|uniprotkb:Map2k2(gene name)|psi-mi:Map2k2(display_short)|uniprotkb:Mek2(gene name synonym)|uniprotkb:Mkk2(gene name synonym)|uniprotkb:Prkmk2(gene name synonym)|uniprotkb:ERK activator kinase 2(gene name synonym)|uniprotkb:MAPK/ERK kinase 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Papin et al. (1996)	mint:MINT-5221085|pubmed:8668348	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8683580|mint:MINT-17043	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_647455.3|go:"GO:0043367"(CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043368"(positive T cell selection)|go:"GO:0043369"(CD4-positive or CD8-positive, alpha-beta T cell lineage commitment)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0048538"(thymus development)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051591"(response to cAMP)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060323"(head morphogenesis)|go:"GO:0060324"(face development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:2000301"(negative regulation of synaptic vesicle exocytosis)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0070413"(trehalose metabolism in response to stress)|interpro:IPR001245(Tyrosine protein kinase)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR003116(Raf-like Ras-binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020454|interpro:IPR029071|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0002318"(myeloid progenitor cell differentiation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0008542"(visual learning)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010764"(negative regulation of fibroblast migration)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035690"|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|reactome:R-MMU-1295596|reactome:R-MMU-5673000|reactome:R-MMU-5674135|reactome:R-MMU-5674499|reactome:R-MMU-5675221|dip:DIP-57050N|reactome:R-MMU-170968|mint:MINT-1518287(identity)	go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0060502"(epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q63932|rcsb pdb:1JKY|reactome:R-MMU-112411|reactome:R-MMU-170968|reactome:R-MMU-445144|reactome:R-MMU-5673000|reactome:R-MMU-5674135|reactome:R-MMU-5674499|ensembl:ENSMUSG00000035027(gene)|ensembl:ENSMUST00000143517(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007507"(heart development)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030878"(thyroid gland development)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048538"(thymus development)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060324"(face development)|refseq:NP_075627.2|dip:DIP-454N|mint:MINT-1518293(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/02/02	2021/02/11	rogid:EblhyDWxW1SHryfZ0Jlabs2rCuw10090	rogid:zFBe4huY3ueH6Rsll7hEcUTUxpI10090	intact-crc:E5C5097051B15D89|rigid:gQKoLiZtL8mLxcG8bIhAswSPiwQ	false	tag:?-?(MINT-1518288)	tag:?-?(MINT-1518294)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)