#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q00526	uniprotkb:Q16667	intact:EBI-1245761|ensembl:ENSP00000400088|ensembl:ENSP00000410561	intact:EBI-1031527|uniprotkb:Q99585|uniprotkb:Q9BPW7|uniprotkb:Q9BY36|uniprotkb:Q9C042|uniprotkb:Q9C047|uniprotkb:Q9C049|uniprotkb:Q9C051|uniprotkb:Q9C053|uniprotkb:Q53ZU6|uniprotkb:Q5U0M4|uniprotkb:Q6P1N8|uniprotkb:Q9C046|ensembl:ENSP00000335357	psi-mi:cdk3_human(display_long)|uniprotkb:CDK3(gene name)|psi-mi:CDK3(display_short)|uniprotkb:Cell division protein kinase 3(gene name synonym)|uniprotkb:CDKN3(gene name synonym)	psi-mi:cdkn3_human(display_long)|uniprotkb:CDKN3(gene name)|psi-mi:CDKN3(display_short)|uniprotkb:CDI1(gene name synonym)|uniprotkb:CIP2(gene name synonym)|uniprotkb:KAP(gene name synonym)|uniprotkb:CDK2-associated dual-specificity phosphatase(gene name synonym)|uniprotkb:Kinase-associated phosphatase(gene name synonym)|uniprotkb:Cyclin-dependent kinase-interacting protein 2(gene name synonym)|uniprotkb:Cyclin-dependent kinase interactor 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Gyuris et al. (1993)	mint:MINT-5220759|pubmed:8242750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8650121|mint:MINT-17536	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001249.1|dip:DIP-686N|ensembl:ENSG00000250506(gene)|ensembl:ENST00000425876(transcript)|ensembl:ENST00000448471(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045023"(G0 to G1 transition)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:1LFN|mint:MINT-1512148(identity)	refseq:NP_001124323.1|refseq:NP_005183.2|ensembl:ENSG00000100526(gene)|ensembl:ENST00000335183(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR008425(Cyclin-dependent kinase inhibitor 3)|interpro:IPR020422|interpro:IPR022778|interpro:IPR029021|rcsb pdb:1FPZ|rcsb pdb:1FQ1|dip:DIP-245N|mint:MINT-1512142(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/08/21	2014/10/16	rogid:3ln4uWhDCiUiI0IcecfT+LKE3MY9606	rogid:PBWyUrbzOD3xk7crMEel4O7WG5A9606	intact-crc:0898D72DEC274230|rigid:4oE9lVFdH+TUV5EkF8SSuR4tMko	false	tag:?-?(MINT-1512149)	tag:?-?(MINT-1512143)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P00546	uniprotkb:Q16667	intact:EBI-4253|uniprotkb:D6VQF5|ensemblfungi:YBR160W	intact:EBI-1031527|uniprotkb:Q99585|uniprotkb:Q9BPW7|uniprotkb:Q9BY36|uniprotkb:Q9C042|uniprotkb:Q9C047|uniprotkb:Q9C049|uniprotkb:Q9C051|uniprotkb:Q9C053|uniprotkb:Q53ZU6|uniprotkb:Q5U0M4|uniprotkb:Q6P1N8|uniprotkb:Q9C046|ensembl:ENSP00000335357	psi-mi:cdk1_yeast(display_long)|uniprotkb:CDC28(gene name)|psi-mi:CDC28(display_short)|uniprotkb:CDK1(gene name synonym)|uniprotkb:HSL5(gene name synonym)|uniprotkb:SRM5(gene name synonym)|uniprotkb:YBR1211(orf name)|uniprotkb:YBR160W(locus name)|uniprotkb:Cell division control protein 28(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym)	psi-mi:cdkn3_human(display_long)|uniprotkb:CDKN3(gene name)|psi-mi:CDKN3(display_short)|uniprotkb:CDI1(gene name synonym)|uniprotkb:CIP2(gene name synonym)|uniprotkb:KAP(gene name synonym)|uniprotkb:CDK2-associated dual-specificity phosphatase(gene name synonym)|uniprotkb:Kinase-associated phosphatase(gene name synonym)|uniprotkb:Cyclin-dependent kinase-interacting protein 2(gene name synonym)|uniprotkb:Cyclin-dependent kinase interactor 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Gyuris et al. (1993)	mint:MINT-5220759|pubmed:8242750	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8650104|mint:MINT-18539	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000364|refseq:NP_009718.3|dip:DIP-1039N|mint:P00546|ensemblfungi:YBR160W(gene)|ensemblfungi:YBR160W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007165"(signal transduction)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010568"(regulation of budding cell apical bud growth)|go:"GO:0010570"(regulation of filamentous growth)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030332"(cyclin binding)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042393"(histone binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0045819"(positive regulation of glycogen catabolic process)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051446"(positive regulation of meiotic cell cycle)|go:"GO:0051447"(negative regulation of meiotic cell cycle)|go:"GO:0060303"(regulation of nucleosome density)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901319"(positive regulation of trehalose catabolic process)|go:"GO:1902596"(negative regulation of DNA replication origin binding)|go:"GO:1902889"(protein localization to spindle microtubule)|go:"GO:1903500"(negative regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1903827"|go:"GO:1904291"(positive regulation of mitotic DNA damage checkpoint)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990139"(protein localization to nuclear periphery)|go:"GO:1990758"(mitotic sister chromatid biorientation)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69017|reactome:R-SCE-69202|reactome:R-SCE-69656|mint:MINT-1512134(identity)	refseq:NP_001124323.1|refseq:NP_005183.2|ensembl:ENSG00000100526(gene)|ensembl:ENST00000335183(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR008425(Cyclin-dependent kinase inhibitor 3)|interpro:IPR020422|interpro:IPR022778|interpro:IPR029021|rcsb pdb:1FPZ|rcsb pdb:1FQ1|dip:DIP-245N|mint:MINT-1512128(identity)	-	crc64:57A7A2B97A90DC6C|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/08/21	2014/10/16	rogid:gYjsHsmOYQGGIVjiQ/ZH+BB9BCM559292	rogid:PBWyUrbzOD3xk7crMEel4O7WG5A9606	intact-crc:3CF599DCE9B7670D|rigid:9/AMH+o3Rk+XrmnY2NB0sYg2CP0	false	tag:?-?(MINT-1512135)	tag:?-?(MINT-1512129)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16667	uniprotkb:P24941	intact:EBI-1031527|uniprotkb:Q99585|uniprotkb:Q9BPW7|uniprotkb:Q9BY36|uniprotkb:Q9C042|uniprotkb:Q9C047|uniprotkb:Q9C049|uniprotkb:Q9C051|uniprotkb:Q9C053|uniprotkb:Q53ZU6|uniprotkb:Q5U0M4|uniprotkb:Q6P1N8|uniprotkb:Q9C046|ensembl:ENSP00000335357	intact:EBI-375096|ensembl:ENSP00000266970|uniprotkb:A8K7C6|uniprotkb:O75100	psi-mi:cdkn3_human(display_long)|uniprotkb:CDKN3(gene name)|psi-mi:CDKN3(display_short)|uniprotkb:CDI1(gene name synonym)|uniprotkb:CIP2(gene name synonym)|uniprotkb:KAP(gene name synonym)|uniprotkb:CDK2-associated dual-specificity phosphatase(gene name synonym)|uniprotkb:Kinase-associated phosphatase(gene name synonym)|uniprotkb:Cyclin-dependent kinase-interacting protein 2(gene name synonym)|uniprotkb:Cyclin-dependent kinase interactor 1(gene name synonym)	psi-mi:cdk2_human(display_long)|uniprotkb:CDK2(gene name)|psi-mi:CDK2(display_short)|uniprotkb:p33 protein kinase(gene name synonym)|uniprotkb:Cell division protein kinase 2(gene name synonym)|uniprotkb:CDKN2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Gyuris et al. (1993)	mint:MINT-5220759|pubmed:8242750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8650171|mint:MINT-17387	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001124323.1|refseq:NP_005183.2|ensembl:ENSG00000100526(gene)|ensembl:ENST00000335183(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR008425(Cyclin-dependent kinase inhibitor 3)|interpro:IPR020422|interpro:IPR022778|interpro:IPR029021|rcsb pdb:1FPZ|rcsb pdb:1FQ1|dip:DIP-245N|mint:MINT-1512182(identity)	ensembl:ENSG00000123374(gene)|ensembl:ENST00000266970(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0015030"(Cajal body)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0060968"(obsolete regulation of gene silencing)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0090398"(cellular senescence)|go:"GO:0097123"(cyclin A1-CDK2 complex)|go:"GO:0097124"(cyclin A2-CDK2 complex)|go:"GO:0097134"(cyclin E1-CDK2 complex)|go:"GO:0097135"(cyclin E2-CDK2 complex)|go:"GO:0097472"(cyclin-dependent protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905784"(regulation of anaphase-promoting complex-dependent catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P24941|rcsb pdb:1AQ1|rcsb pdb:1B39|rcsb pdb:1B38|rcsb pdb:1BUH|rcsb pdb:1CKP|rcsb pdb:1DI8|rcsb pdb:1DM2|rcsb pdb:1E1V|rcsb pdb:1E1X|rcsb pdb:1E9H|rcsb pdb:1F5Q|rcsb pdb:1FIN|rcsb pdb:1FQ1|rcsb pdb:1FVT|rcsb pdb:1FVV|rcsb pdb:1G5S|rcsb pdb:1GIH|rcsb pdb:1GII|rcsb pdb:1GIJ|rcsb pdb:1GY3|rcsb pdb:3R6X|rcsb pdb:3R71|rcsb pdb:3R73|rcsb pdb:3R7E|rcsb pdb:3R7I|rcsb pdb:3R7U|rcsb pdb:3R7V|rcsb pdb:3R7Y|rcsb pdb:3R83|rcsb pdb:3R8L|rcsb pdb:3R8M|rcsb pdb:3R8P|rcsb pdb:3R8U|rcsb pdb:3R8V|rcsb pdb:3R8Z|rcsb pdb:3R9D|rcsb pdb:3R9H|rcsb pdb:3R9N|rcsb pdb:3R9O|rcsb pdb:3RAH|rcsb pdb:3RAI|rcsb pdb:3RAK|rcsb pdb:3RAL|rcsb pdb:3RJC|refseq:NP_001789.2|refseq:NP_439892.2|rcsb pdb:1URC|rcsb pdb:1URW|rcsb pdb:1V1K|rcsb pdb:1VYW|rcsb pdb:1VYZ|rcsb pdb:1W0X|rcsb pdb:1W8C|rcsb pdb:1GZ8|rcsb pdb:1H00|rcsb pdb:1H01|rcsb pdb:1H07|rcsb pdb:1H08|rcsb pdb:1H0V|rcsb pdb:1H0W|rcsb pdb:1H1P|rcsb pdb:1H1Q|rcsb pdb:1H1R|rcsb pdb:1H1S|rcsb pdb:1H24|rcsb pdb:1H25|rcsb pdb:1H26|rcsb pdb:1H27|rcsb pdb:1H28|rcsb pdb:1HCK|rcsb pdb:1HCL|rcsb pdb:1JST|rcsb pdb:1JSU|rcsb pdb:1JSV|rcsb pdb:1JVP|rcsb pdb:1KE5|rcsb pdb:1KE6|rcsb pdb:1KE7|rcsb pdb:1KE8|rcsb pdb:1KE9|rcsb pdb:1OGU|rcsb pdb:1OI9|rcsb pdb:1OIQ|rcsb pdb:1OIR|rcsb pdb:1OIT|rcsb pdb:1OIU|rcsb pdb:1OIY|rcsb pdb:1OKV|rcsb pdb:1OKW|rcsb pdb:1OL1|rcsb pdb:1OL2|rcsb pdb:1P2A|rcsb pdb:1P5E|rcsb pdb:1PF8|rcsb pdb:1PKD|rcsb pdb:1PW2|rcsb pdb:1PXI|rcsb pdb:1PXJ|rcsb pdb:1PXK|rcsb pdb:1PXL|rcsb pdb:1PXM|rcsb pdb:1PXN|rcsb pdb:1PXO|rcsb pdb:1PXP|rcsb pdb:1PYE|rcsb pdb:1QMZ|rcsb pdb:1R78|rcsb pdb:1W98|rcsb pdb:1WCC|rcsb pdb:1Y8Y|rcsb pdb:1Y91|rcsb pdb:1YKR|rcsb pdb:2A0C|rcsb pdb:2A4L|rcsb pdb:2B52|rcsb pdb:2B53|rcsb pdb:2B54|rcsb pdb:2B55|rcsb pdb:2BHE|rcsb pdb:2BHH|rcsb pdb:2BKZ|rcsb pdb:2BPM|rcsb pdb:2BTR|rcsb pdb:2BTS|rcsb pdb:2C4G|rcsb pdb:2C5N|rcsb pdb:2C5O|rcsb pdb:2C5V|rcsb pdb:2C5X|rcsb pdb:2C5Y|rcsb pdb:2C68|rcsb pdb:2C69|rcsb pdb:2C6I|rcsb pdb:2C6K|rcsb pdb:2C6L|rcsb pdb:2C6M|rcsb pdb:2C6O|rcsb pdb:2C6T|rcsb pdb:2CCH|rcsb pdb:2CCI|rcsb pdb:3BHT|rcsb pdb:2CJM|rcsb pdb:2CLX|rcsb pdb:2DS1|rcsb pdb:2DUV|rcsb pdb:2EXM|rcsb pdb:2FVD|rcsb pdb:2G9X|rcsb pdb:2HIC|rcsb pdb:2I40|rcsb pdb:2IW6|rcsb pdb:2IW8|rcsb pdb:2IW9|rcsb pdb:2J9M|rcsb pdb:2JGZ|rcsb pdb:2R3F|rcsb pdb:2R3G|rcsb pdb:2R3H|rcsb pdb:2R3I|rcsb pdb:2R3J|rcsb pdb:2R3K|rcsb pdb:2R3L|rcsb pdb:2R3M|rcsb pdb:2R3N|rcsb pdb:2R3O|rcsb pdb:2R3P|rcsb pdb:2R3Q|rcsb pdb:2R3R|rcsb pdb:2R64|rcsb pdb:2UUE|rcsb pdb:2UZB|rcsb pdb:2UZD|rcsb pdb:2UZE|rcsb pdb:2UZL|rcsb pdb:2UZN|rcsb pdb:2UZO|rcsb pdb:2V0D|rcsb pdb:2V22|rcsb pdb:2VTA|rcsb pdb:2VTH|rcsb pdb:2VTI|rcsb pdb:2VTJ|rcsb pdb:2VTL|rcsb pdb:2VTM|rcsb pdb:2VTN|rcsb pdb:2VTO|rcsb pdb:2VTP|rcsb pdb:2VTQ|rcsb pdb:2VTR|rcsb pdb:2VTS|rcsb pdb:2VTT|rcsb pdb:2VU3|rcsb pdb:2VV9|rcsb pdb:2W05|rcsb pdb:2W06|rcsb pdb:2W17|rcsb pdb:2W1H|rcsb pdb:2WEV|rcsb pdb:2WFY|rcsb pdb:2WHB|rcsb pdb:2WIH|rcsb pdb:2WIP|rcsb pdb:2WMA|rcsb pdb:2WMB|rcsb pdb:2WPA|rcsb pdb:2WXV|rcsb pdb:2X1N|rcsb pdb:2XMY|rcsb pdb:2XNB|rcsb pdb:3BHU|rcsb pdb:3BHV|rcsb pdb:3DDP|rcsb pdb:3DDQ|rcsb pdb:3DOG|rcsb pdb:3EID|rcsb pdb:3EJ1|rcsb pdb:3EOC|rcsb pdb:3EZR|rcsb pdb:3EZV|rcsb pdb:3F5X|rcsb pdb:3FZ1|rcsb pdb:3IG7|rcsb pdb:3IGG|rcsb pdb:3LE6|rcsb pdb:3LFN|rcsb pdb:3LFQ|rcsb pdb:3LFS|rcsb pdb:3MY5|rcsb pdb:3NS9|rcsb pdb:3PJ8|rcsb pdb:3PXF|rcsb pdb:3PXQ|rcsb pdb:3PXR|rcsb pdb:3PXY|rcsb pdb:3PXZ|rcsb pdb:3PY0|rcsb pdb:3PY1|rcsb pdb:3QHR|rcsb pdb:3QHW|rcsb pdb:3QL8|rcsb pdb:3QQF|rcsb pdb:3QQG|rcsb pdb:3QQH|rcsb pdb:3QQJ|rcsb pdb:3QQK|rcsb pdb:3QQL|rcsb pdb:3QRT|rcsb pdb:3QRU|rcsb pdb:3QTQ|rcsb pdb:3QTR|rcsb pdb:3QTS|rcsb pdb:3QTU|rcsb pdb:3QTW|rcsb pdb:3QTX|rcsb pdb:3QTZ|rcsb pdb:3QU0|rcsb pdb:3QWJ|rcsb pdb:3QWK|rcsb pdb:3QX2|rcsb pdb:3QX4|rcsb pdb:3QXO|rcsb pdb:3QXP|rcsb pdb:3QZF|rcsb pdb:3QZG|rcsb pdb:3QZH|rcsb pdb:3QZI|rcsb pdb:3R1Q|rcsb pdb:3R1S|rcsb pdb:3R1Y|rcsb pdb:3R28|refseq:NP_001277159.1|rcsb pdb:3RK5|rcsb pdb:3RK7|rcsb pdb:3RK9|rcsb pdb:3RKB|rcsb pdb:3RM6|rcsb pdb:3RM7|rcsb pdb:3RMF|rcsb pdb:3RNI|rcsb pdb:3ROY|rcsb pdb:3RPO|rcsb pdb:3RPR|rcsb pdb:3RPV|rcsb pdb:3RPY|rcsb pdb:3RZB|rcsb pdb:3S00|rcsb pdb:3S0O|rcsb pdb:3S1H|rcsb pdb:3S2P|rcsb pdb:3SQQ|rcsb pdb:3SW4|rcsb pdb:3SW7|rcsb pdb:3TI1|rcsb pdb:3TIY|rcsb pdb:3TIZ|rcsb pdb:3TNW|rcsb pdb:3ULI|rcsb pdb:3UNJ|rcsb pdb:3UNK|rcsb pdb:3WBL|rcsb pdb:4ACM|rcsb pdb:4BCK|rcsb pdb:4BCM|rcsb pdb:4BCN|rcsb pdb:4BCO|rcsb pdb:4BCP|rcsb pdb:4BCQ|rcsb pdb:4BGH|rcsb pdb:4BZD|rcsb pdb:4CFM|rcsb pdb:4CFN|rcsb pdb:4CFU|rcsb pdb:4CFV|rcsb pdb:4CFW|rcsb pdb:4CFX|rcsb pdb:4D1X|rcsb pdb:4D1Z|rcsb pdb:4EK3|rcsb pdb:4EK4|rcsb pdb:4EK5|rcsb pdb:4EK6|rcsb pdb:4EK8|rcsb pdb:4EOI|rcsb pdb:4EOJ|rcsb pdb:4EOK|rcsb pdb:4EOL|rcsb pdb:4EOM|rcsb pdb:4EON|rcsb pdb:4EOO|rcsb pdb:4EOP|rcsb pdb:4EOQ|rcsb pdb:4EOR|rcsb pdb:4EOS|rcsb pdb:4ERW|rcsb pdb:4EZ3|rcsb pdb:4EZ7|rcsb pdb:4FKG|rcsb pdb:4FKI|rcsb pdb:4FKJ|rcsb pdb:4FKL|rcsb pdb:4FKO|rcsb pdb:4FKP|rcsb pdb:4FKQ|rcsb pdb:4FKR|rcsb pdb:4FKS|rcsb pdb:4FKT|rcsb pdb:4FKU|rcsb pdb:4FKV|rcsb pdb:4FKW|rcsb pdb:4FX3|rcsb pdb:4GCJ|rcsb pdb:4I3Z|rcsb pdb:4II5|rcsb pdb:4KD1|rcsb pdb:4LYN|rcsb pdb:5IEV|rcsb pdb:5IEX|rcsb pdb:5IEY|rcsb pdb:5IF1|rcsb pdb:5JQ5|rcsb pdb:5JQ8|rcsb pdb:5K4J|rcsb pdb:5L2W|rcsb pdb:5LMK|rcsb pdb:5MHQ|rcsb pdb:5NEV|rcsb pdb:5OO0|rcsb pdb:5OO1|rcsb pdb:5OO3|rcsb pdb:5OSJ|rcsb pdb:5OSM|rcsb pdb:5UQ1|rcsb pdb:5UQ2|rcsb pdb:5UQ3|rcsb pdb:6ATH|rcsb pdb:6GUB|rcsb pdb:6GUC|rcsb pdb:6GUE|rcsb pdb:6GUF|rcsb pdb:6GUH|rcsb pdb:6GUK|rcsb pdb:6GVA|rcsb pdb:6INL|rcsb pdb:6JGM|rcsb pdb:4NJ3|rcsb pdb:4RJ3|rcsb pdb:5A14|rcsb pdb:5AND|rcsb pdb:5ANE|rcsb pdb:5ANG|rcsb pdb:5ANI|rcsb pdb:5ANJ|rcsb pdb:5ANK|rcsb pdb:5ANO|rcsb pdb:5CYI|rcsb pdb:5D1J|rcsb pdb:5FP5|rcsb pdb:5FP6|rcsb pdb:6OQI|rcsb pdb:6P3W|rcsb pdb:6Q3B|rcsb pdb:6Q3C|rcsb pdb:6Q3F|rcsb pdb:6Q48|rcsb pdb:6Q49|rcsb pdb:6Q4A|rcsb pdb:6Q4B|rcsb pdb:6Q4C|rcsb pdb:6Q4D|rcsb pdb:6Q4E|rcsb pdb:6Q4F|rcsb pdb:6Q4G|rcsb pdb:6Q4H|rcsb pdb:6Q4I|rcsb pdb:6Q4J|rcsb pdb:6Q4K|rcsb pdb:6RIJ|rcsb pdb:6SG4|rcsb pdb:6YL1|rcsb pdb:6YL6|rcsb pdb:6YLK|rcsb pdb:7ACK|rcsb pdb:7B5L|rcsb pdb:7B5R|rcsb pdb:7E34|rcsb pdb:7KJS|rcsb pdb:7NVQ|reactome:R-HSA-1538133|reactome:R-HSA-171319|reactome:R-HSA-176187|reactome:R-HSA-176408|reactome:R-HSA-187577|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5693607|reactome:R-HSA-6804116|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-68911|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69017|reactome:R-HSA-69200|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-8849470|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9661069|reactome:R-HSA-983231|dip:DIP-161N|mint:MINT-1512188(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/08/21	2014/10/16	rogid:PBWyUrbzOD3xk7crMEel4O7WG5A9606	rogid:ysjMzOZyhhtpss+M7hJCqtLahFQ9606	intact-crc:80A35666E9B4221B|rigid:T1YSyPRm7WV9fWncEN79qrMN+2c	false	tag:?-?(MINT-1512183)	O4'-phospho-L-tyrosine:160-160(MINT-1512189)|tag:?-?(MINT-1512191)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06493	uniprotkb:Q16667	intact:EBI-444308|ensembl:ENSP00000378699|uniprotkb:O60764|uniprotkb:C9J497|uniprotkb:A8K7C4	intact:EBI-1031527|uniprotkb:Q99585|uniprotkb:Q9BPW7|uniprotkb:Q9BY36|uniprotkb:Q9C042|uniprotkb:Q9C047|uniprotkb:Q9C049|uniprotkb:Q9C051|uniprotkb:Q9C053|uniprotkb:Q53ZU6|uniprotkb:Q5U0M4|uniprotkb:Q6P1N8|uniprotkb:Q9C046|ensembl:ENSP00000335357	psi-mi:cdk1_human(display_long)|uniprotkb:p34 protein kinase(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym)|uniprotkb:CDK1(gene name)|psi-mi:CDK1(display_short)|uniprotkb:CDC2(gene name synonym)|uniprotkb:Cell division control protein 2 homolog(gene name synonym)|uniprotkb:CDC28A(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:P34CDC2(gene name synonym)	psi-mi:cdkn3_human(display_long)|uniprotkb:CDKN3(gene name)|psi-mi:CDKN3(display_short)|uniprotkb:CDI1(gene name synonym)|uniprotkb:CIP2(gene name synonym)|uniprotkb:KAP(gene name synonym)|uniprotkb:CDK2-associated dual-specificity phosphatase(gene name synonym)|uniprotkb:Kinase-associated phosphatase(gene name synonym)|uniprotkb:Cyclin-dependent kinase-interacting protein 2(gene name synonym)|uniprotkb:Cyclin-dependent kinase interactor 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Gyuris et al. (1993)	mint:MINT-5220759|pubmed:8242750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8650137|mint:MINT-14184	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007344"(pronuclear fusion)|go:"GO:0007569"(cell aging)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0014038"(regulation of Schwann cell differentiation)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014075"(response to amine)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030332"(cyclin binding)|go:"GO:0030496"(midbody)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035173"(histone kinase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046688"(response to copper ion)|go:"GO:0048511"(rhythmic process)|go:"GO:0048678"(response to axon injury)|go:"GO:0051301"(cell division)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0042493"|go:"GO:0072686"(mitotic spindle)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0097125"(cyclin B1-CDK1 complex)|go:"GO:0097472"(cyclin-dependent protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P06493|rcsb pdb:1LC9|rcsb pdb:4Y72|rcsb pdb:4YC3|rcsb pdb:4YC6|rcsb pdb:5HQ0|rcsb pdb:5LQF|rcsb pdb:6GU2|rcsb pdb:6GU3|rcsb pdb:6GU4|rcsb pdb:6GU6|go:"GO:0042752"(regulation of circadian rhythm)|rcsb pdb:6GU7|rcsb pdb:6TWN|reactome:R-HSA-110056|reactome:R-HSA-113507|reactome:R-HSA-1362300|reactome:R-HSA-162658|reactome:R-HSA-170145|reactome:R-HSA-174048|reactome:R-HSA-174184|reactome:R-HSA-176408|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|reactome:R-HSA-2465910|reactome:R-HSA-2500257|reactome:R-HSA-2514853|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-2995383|reactome:R-HSA-3301854|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-4419969|reactome:R-HSA-5620912|reactome:R-HSA-5687128|reactome:R-HSA-5689896|reactome:R-HSA-6804114|reactome:R-HSA-6804757|reactome:R-HSA-68875|reactome:R-HSA-69205|reactome:R-HSA-69273|reactome:R-HSA-69478|reactome:R-HSA-75035|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8878166|ensembl:ENSG00000170312(gene)|ensembl:ENST00000395284(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001618"(virus receptor activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|refseq:NP_001777.1|refseq:NP_203698.1|refseq:XP_005270360.1|refseq:NP_001307847.1|dip:DIP-35N|mint:MINT-1512156(identity)	refseq:NP_001124323.1|refseq:NP_005183.2|ensembl:ENSG00000100526(gene)|ensembl:ENST00000335183(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR008425(Cyclin-dependent kinase inhibitor 3)|interpro:IPR020422|interpro:IPR022778|interpro:IPR029021|rcsb pdb:1FPZ|rcsb pdb:1FQ1|dip:DIP-245N|mint:MINT-1512162(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/08/21	2014/10/16	rogid:8geyXVp0Rpm8sG8I76/XgWsZ4JA9606	rogid:PBWyUrbzOD3xk7crMEel4O7WG5A9606	intact-crc:DC91C8DBD60D26A4|rigid:awjxVGJOfIf10lP4yzsagFTycSU	false	tag:?-?(MINT-1512157)	tag:?-?(MINT-1512163)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P24941	uniprotkb:Q16667	intact:EBI-375096|ensembl:ENSP00000266970|uniprotkb:A8K7C6|uniprotkb:O75100	intact:EBI-1031527|uniprotkb:Q99585|uniprotkb:Q9BPW7|uniprotkb:Q9BY36|uniprotkb:Q9C042|uniprotkb:Q9C047|uniprotkb:Q9C049|uniprotkb:Q9C051|uniprotkb:Q9C053|uniprotkb:Q53ZU6|uniprotkb:Q5U0M4|uniprotkb:Q6P1N8|uniprotkb:Q9C046|ensembl:ENSP00000335357	psi-mi:cdk2_human(display_long)|uniprotkb:CDK2(gene name)|psi-mi:CDK2(display_short)|uniprotkb:p33 protein kinase(gene name synonym)|uniprotkb:Cell division protein kinase 2(gene name synonym)|uniprotkb:CDKN2(gene name synonym)	psi-mi:cdkn3_human(display_long)|uniprotkb:CDKN3(gene name)|psi-mi:CDKN3(display_short)|uniprotkb:CDI1(gene name synonym)|uniprotkb:CIP2(gene name synonym)|uniprotkb:KAP(gene name synonym)|uniprotkb:CDK2-associated dual-specificity phosphatase(gene name synonym)|uniprotkb:Kinase-associated phosphatase(gene name synonym)|uniprotkb:Cyclin-dependent kinase-interacting protein 2(gene name synonym)|uniprotkb:Cyclin-dependent kinase interactor 1(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Gyuris et al. (1993)	mint:MINT-5220759|pubmed:8242750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8650201|mint:MINT-17388	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000123374(gene)|ensembl:ENST00000266970(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0015030"(Cajal body)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0060968"(obsolete regulation of gene silencing)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0090398"(cellular senescence)|go:"GO:0097123"(cyclin A1-CDK2 complex)|go:"GO:0097124"(cyclin A2-CDK2 complex)|go:"GO:0097134"(cyclin E1-CDK2 complex)|go:"GO:0097135"(cyclin E2-CDK2 complex)|go:"GO:0097472"(cyclin-dependent protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905784"(regulation of anaphase-promoting complex-dependent catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P24941|rcsb pdb:1AQ1|rcsb pdb:1B39|rcsb pdb:1B38|rcsb pdb:1BUH|rcsb pdb:1CKP|rcsb pdb:1DI8|rcsb pdb:1DM2|rcsb pdb:1E1V|rcsb pdb:1E1X|rcsb pdb:1E9H|rcsb pdb:1F5Q|rcsb pdb:1FIN|rcsb pdb:1FQ1|rcsb pdb:1FVT|rcsb pdb:1FVV|rcsb pdb:1G5S|rcsb pdb:1GIH|rcsb pdb:1GII|rcsb pdb:1GIJ|rcsb pdb:1GY3|rcsb pdb:3R6X|rcsb pdb:3R71|rcsb pdb:3R73|rcsb pdb:3R7E|rcsb pdb:3R7I|rcsb pdb:3R7U|rcsb pdb:3R7V|rcsb pdb:3R7Y|rcsb pdb:3R83|rcsb pdb:3R8L|rcsb pdb:3R8M|rcsb pdb:3R8P|rcsb pdb:3R8U|rcsb pdb:3R8V|rcsb pdb:3R8Z|rcsb pdb:3R9D|rcsb pdb:3R9H|rcsb pdb:3R9N|rcsb pdb:3R9O|rcsb pdb:3RAH|rcsb pdb:3RAI|rcsb pdb:3RAK|rcsb pdb:3RAL|rcsb pdb:3RJC|refseq:NP_001789.2|refseq:NP_439892.2|rcsb pdb:1URC|rcsb pdb:1URW|rcsb pdb:1V1K|rcsb pdb:1VYW|rcsb pdb:1VYZ|rcsb pdb:1W0X|rcsb pdb:1W8C|rcsb pdb:1GZ8|rcsb pdb:1H00|rcsb pdb:1H01|rcsb pdb:1H07|rcsb pdb:1H08|rcsb pdb:1H0V|rcsb pdb:1H0W|rcsb pdb:1H1P|rcsb pdb:1H1Q|rcsb pdb:1H1R|rcsb pdb:1H1S|rcsb pdb:1H24|rcsb pdb:1H25|rcsb pdb:1H26|rcsb pdb:1H27|rcsb pdb:1H28|rcsb pdb:1HCK|rcsb pdb:1HCL|rcsb pdb:1JST|rcsb pdb:1JSU|rcsb pdb:1JSV|rcsb pdb:1JVP|rcsb pdb:1KE5|rcsb pdb:1KE6|rcsb pdb:1KE7|rcsb pdb:1KE8|rcsb pdb:1KE9|rcsb pdb:1OGU|rcsb pdb:1OI9|rcsb pdb:1OIQ|rcsb pdb:1OIR|rcsb pdb:1OIT|rcsb pdb:1OIU|rcsb pdb:1OIY|rcsb pdb:1OKV|rcsb pdb:1OKW|rcsb pdb:1OL1|rcsb pdb:1OL2|rcsb pdb:1P2A|rcsb pdb:1P5E|rcsb pdb:1PF8|rcsb pdb:1PKD|rcsb pdb:1PW2|rcsb pdb:1PXI|rcsb pdb:1PXJ|rcsb pdb:1PXK|rcsb pdb:1PXL|rcsb pdb:1PXM|rcsb pdb:1PXN|rcsb pdb:1PXO|rcsb pdb:1PXP|rcsb pdb:1PYE|rcsb pdb:1QMZ|rcsb pdb:1R78|rcsb pdb:1W98|rcsb pdb:1WCC|rcsb pdb:1Y8Y|rcsb pdb:1Y91|rcsb pdb:1YKR|rcsb pdb:2A0C|rcsb pdb:2A4L|rcsb pdb:2B52|rcsb pdb:2B53|rcsb pdb:2B54|rcsb pdb:2B55|rcsb pdb:2BHE|rcsb pdb:2BHH|rcsb pdb:2BKZ|rcsb pdb:2BPM|rcsb pdb:2BTR|rcsb pdb:2BTS|rcsb pdb:2C4G|rcsb pdb:2C5N|rcsb pdb:2C5O|rcsb pdb:2C5V|rcsb pdb:2C5X|rcsb pdb:2C5Y|rcsb pdb:2C68|rcsb pdb:2C69|rcsb pdb:2C6I|rcsb pdb:2C6K|rcsb pdb:2C6L|rcsb pdb:2C6M|rcsb pdb:2C6O|rcsb pdb:2C6T|rcsb pdb:2CCH|rcsb pdb:2CCI|rcsb pdb:3BHT|rcsb pdb:2CJM|rcsb pdb:2CLX|rcsb pdb:2DS1|rcsb pdb:2DUV|rcsb pdb:2EXM|rcsb pdb:2FVD|rcsb pdb:2G9X|rcsb pdb:2HIC|rcsb pdb:2I40|rcsb pdb:2IW6|rcsb pdb:2IW8|rcsb pdb:2IW9|rcsb pdb:2J9M|rcsb pdb:2JGZ|rcsb pdb:2R3F|rcsb pdb:2R3G|rcsb pdb:2R3H|rcsb pdb:2R3I|rcsb pdb:2R3J|rcsb pdb:2R3K|rcsb pdb:2R3L|rcsb pdb:2R3M|rcsb pdb:2R3N|rcsb pdb:2R3O|rcsb pdb:2R3P|rcsb pdb:2R3Q|rcsb pdb:2R3R|rcsb pdb:2R64|rcsb pdb:2UUE|rcsb pdb:2UZB|rcsb pdb:2UZD|rcsb pdb:2UZE|rcsb pdb:2UZL|rcsb pdb:2UZN|rcsb pdb:2UZO|rcsb pdb:2V0D|rcsb pdb:2V22|rcsb pdb:2VTA|rcsb pdb:2VTH|rcsb pdb:2VTI|rcsb pdb:2VTJ|rcsb pdb:2VTL|rcsb pdb:2VTM|rcsb pdb:2VTN|rcsb pdb:2VTO|rcsb pdb:2VTP|rcsb pdb:2VTQ|rcsb pdb:2VTR|rcsb pdb:2VTS|rcsb pdb:2VTT|rcsb pdb:2VU3|rcsb pdb:2VV9|rcsb pdb:2W05|rcsb pdb:2W06|rcsb pdb:2W17|rcsb pdb:2W1H|rcsb pdb:2WEV|rcsb pdb:2WFY|rcsb pdb:2WHB|rcsb pdb:2WIH|rcsb pdb:2WIP|rcsb pdb:2WMA|rcsb pdb:2WMB|rcsb pdb:2WPA|rcsb pdb:2WXV|rcsb pdb:2X1N|rcsb pdb:2XMY|rcsb pdb:2XNB|rcsb pdb:3BHU|rcsb pdb:3BHV|rcsb pdb:3DDP|rcsb pdb:3DDQ|rcsb pdb:3DOG|rcsb pdb:3EID|rcsb pdb:3EJ1|rcsb pdb:3EOC|rcsb pdb:3EZR|rcsb pdb:3EZV|rcsb pdb:3F5X|rcsb pdb:3FZ1|rcsb pdb:3IG7|rcsb pdb:3IGG|rcsb pdb:3LE6|rcsb pdb:3LFN|rcsb pdb:3LFQ|rcsb pdb:3LFS|rcsb pdb:3MY5|rcsb pdb:3NS9|rcsb pdb:3PJ8|rcsb pdb:3PXF|rcsb pdb:3PXQ|rcsb pdb:3PXR|rcsb pdb:3PXY|rcsb pdb:3PXZ|rcsb pdb:3PY0|rcsb pdb:3PY1|rcsb pdb:3QHR|rcsb pdb:3QHW|rcsb pdb:3QL8|rcsb pdb:3QQF|rcsb pdb:3QQG|rcsb pdb:3QQH|rcsb pdb:3QQJ|rcsb pdb:3QQK|rcsb pdb:3QQL|rcsb pdb:3QRT|rcsb pdb:3QRU|rcsb pdb:3QTQ|rcsb pdb:3QTR|rcsb pdb:3QTS|rcsb pdb:3QTU|rcsb pdb:3QTW|rcsb pdb:3QTX|rcsb pdb:3QTZ|rcsb pdb:3QU0|rcsb pdb:3QWJ|rcsb pdb:3QWK|rcsb pdb:3QX2|rcsb pdb:3QX4|rcsb pdb:3QXO|rcsb pdb:3QXP|rcsb pdb:3QZF|rcsb pdb:3QZG|rcsb pdb:3QZH|rcsb pdb:3QZI|rcsb pdb:3R1Q|rcsb pdb:3R1S|rcsb pdb:3R1Y|rcsb pdb:3R28|refseq:NP_001277159.1|rcsb pdb:3RK5|rcsb pdb:3RK7|rcsb pdb:3RK9|rcsb pdb:3RKB|rcsb pdb:3RM6|rcsb pdb:3RM7|rcsb pdb:3RMF|rcsb pdb:3RNI|rcsb pdb:3ROY|rcsb pdb:3RPO|rcsb pdb:3RPR|rcsb pdb:3RPV|rcsb pdb:3RPY|rcsb pdb:3RZB|rcsb pdb:3S00|rcsb pdb:3S0O|rcsb pdb:3S1H|rcsb pdb:3S2P|rcsb pdb:3SQQ|rcsb pdb:3SW4|rcsb pdb:3SW7|rcsb pdb:3TI1|rcsb pdb:3TIY|rcsb pdb:3TIZ|rcsb pdb:3TNW|rcsb pdb:3ULI|rcsb pdb:3UNJ|rcsb pdb:3UNK|rcsb pdb:3WBL|rcsb pdb:4ACM|rcsb pdb:4BCK|rcsb pdb:4BCM|rcsb pdb:4BCN|rcsb pdb:4BCO|rcsb pdb:4BCP|rcsb pdb:4BCQ|rcsb pdb:4BGH|rcsb pdb:4BZD|rcsb pdb:4CFM|rcsb pdb:4CFN|rcsb pdb:4CFU|rcsb pdb:4CFV|rcsb pdb:4CFW|rcsb pdb:4CFX|rcsb pdb:4D1X|rcsb pdb:4D1Z|rcsb pdb:4EK3|rcsb pdb:4EK4|rcsb pdb:4EK5|rcsb pdb:4EK6|rcsb pdb:4EK8|rcsb pdb:4EOI|rcsb pdb:4EOJ|rcsb pdb:4EOK|rcsb pdb:4EOL|rcsb pdb:4EOM|rcsb pdb:4EON|rcsb pdb:4EOO|rcsb pdb:4EOP|rcsb pdb:4EOQ|rcsb pdb:4EOR|rcsb pdb:4EOS|rcsb pdb:4ERW|rcsb pdb:4EZ3|rcsb pdb:4EZ7|rcsb pdb:4FKG|rcsb pdb:4FKI|rcsb pdb:4FKJ|rcsb pdb:4FKL|rcsb pdb:4FKO|rcsb pdb:4FKP|rcsb pdb:4FKQ|rcsb pdb:4FKR|rcsb pdb:4FKS|rcsb pdb:4FKT|rcsb pdb:4FKU|rcsb pdb:4FKV|rcsb pdb:4FKW|rcsb pdb:4FX3|rcsb pdb:4GCJ|rcsb pdb:4I3Z|rcsb pdb:4II5|rcsb pdb:4KD1|rcsb pdb:4LYN|rcsb pdb:5IEV|rcsb pdb:5IEX|rcsb pdb:5IEY|rcsb pdb:5IF1|rcsb pdb:5JQ5|rcsb pdb:5JQ8|rcsb pdb:5K4J|rcsb pdb:5L2W|rcsb pdb:5LMK|rcsb pdb:5MHQ|rcsb pdb:5NEV|rcsb pdb:5OO0|rcsb pdb:5OO1|rcsb pdb:5OO3|rcsb pdb:5OSJ|rcsb pdb:5OSM|rcsb pdb:5UQ1|rcsb pdb:5UQ2|rcsb pdb:5UQ3|rcsb pdb:6ATH|rcsb pdb:6GUB|rcsb pdb:6GUC|rcsb pdb:6GUE|rcsb pdb:6GUF|rcsb pdb:6GUH|rcsb pdb:6GUK|rcsb pdb:6GVA|rcsb pdb:6INL|rcsb pdb:6JGM|rcsb pdb:4NJ3|rcsb pdb:4RJ3|rcsb pdb:5A14|rcsb pdb:5AND|rcsb pdb:5ANE|rcsb pdb:5ANG|rcsb pdb:5ANI|rcsb pdb:5ANJ|rcsb pdb:5ANK|rcsb pdb:5ANO|rcsb pdb:5CYI|rcsb pdb:5D1J|rcsb pdb:5FP5|rcsb pdb:5FP6|rcsb pdb:6OQI|rcsb pdb:6P3W|rcsb pdb:6Q3B|rcsb pdb:6Q3C|rcsb pdb:6Q3F|rcsb pdb:6Q48|rcsb pdb:6Q49|rcsb pdb:6Q4A|rcsb pdb:6Q4B|rcsb pdb:6Q4C|rcsb pdb:6Q4D|rcsb pdb:6Q4E|rcsb pdb:6Q4F|rcsb pdb:6Q4G|rcsb pdb:6Q4H|rcsb pdb:6Q4I|rcsb pdb:6Q4J|rcsb pdb:6Q4K|rcsb pdb:6RIJ|rcsb pdb:6SG4|rcsb pdb:6YL1|rcsb pdb:6YL6|rcsb pdb:6YLK|rcsb pdb:7ACK|rcsb pdb:7B5L|rcsb pdb:7B5R|rcsb pdb:7E34|rcsb pdb:7KJS|rcsb pdb:7NVQ|reactome:R-HSA-1538133|reactome:R-HSA-171319|reactome:R-HSA-176187|reactome:R-HSA-176408|reactome:R-HSA-187577|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5693607|reactome:R-HSA-6804116|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-68911|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69017|reactome:R-HSA-69200|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-8849470|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9661069|reactome:R-HSA-983231|dip:DIP-161N|mint:MINT-1512175(identity)	refseq:NP_001124323.1|refseq:NP_005183.2|ensembl:ENSG00000100526(gene)|ensembl:ENST00000335183(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR008425(Cyclin-dependent kinase inhibitor 3)|interpro:IPR020422|interpro:IPR022778|interpro:IPR029021|rcsb pdb:1FPZ|rcsb pdb:1FQ1|dip:DIP-245N|mint:MINT-1512172(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/08/21	2014/10/16	rogid:ysjMzOZyhhtpss+M7hJCqtLahFQ9606	rogid:PBWyUrbzOD3xk7crMEel4O7WG5A9606	intact-crc:AF18CE668CBF8457|rigid:T1YSyPRm7WV9fWncEN79qrMN+2c	false	O4'-phospho-L-tyrosine:160-160(MINT-1512176)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)