#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O15061 uniprotkb:Q9Y4J8 intact:EBI-7843148|intact:EBI-28977600|ensembl:ENSP00000336775|intact:MINT-198289|uniprotkb:Q2TBJ4|uniprotkb:Q5NJJ9|uniprotkb:Q8TE62|uniprotkb:A7E2Y2|uniprotkb:Q8TE61 intact:EBI-949471|ensembl:ENSP00000382064|uniprotkb:O15332|uniprotkb:O15333|uniprotkb:O75697|uniprotkb:Q13197|uniprotkb:Q13198|uniprotkb:Q13199|uniprotkb:Q13498|uniprotkb:Q13499|uniprotkb:Q13500|uniprotkb:A8MUY4|uniprotkb:A8K541|uniprotkb:M0QYX6|uniprotkb:A8MSZ0|uniprotkb:Q9BS59|uniprotkb:B4DIU8|uniprotkb:B4DIR0|uniprotkb:B4DGS6|uniprotkb:M0R397|uniprotkb:Q59GK7 psi-mi:synem_human(display_long)|uniprotkb:KIAA0353(gene name synonym)|uniprotkb:DMN(gene name synonym)|uniprotkb:SYN(gene name synonym)|uniprotkb:Desmuslin(gene name synonym)|uniprotkb:SYNM(gene name)|psi-mi:SYNM(display_short) psi-mi:dtna_human(display_long)|uniprotkb:Alpha-dystrobrevin(gene name synonym)|uniprotkb:Dystrophin-related protein 3(gene name synonym)|uniprotkb:DTNA(gene name)|psi-mi:DTNA(display_short)|uniprotkb:DRP3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Mizuno et al. (2001) pubmed:11353857|mint:MINT-5214016 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7843144|mint:MINT-18684 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000336775|ensembl:ENSG00000182253(gene)|ensembl:ENST00000336292(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005912"(adherens junction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017166"(vinculin binding)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0031443"(fast-twitch skeletal muscle fiber contraction)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0060053"(neurofilament cytoskeleton)|interpro:IPR018039|interpro:IPR030634|interpro:IPR039008|rcsb pdb:6EWO|refseq:NP_056101.5|refseq:NP_663780.2|mint:MINT-577458(identity) ensembl:ENSG00000134769(gene)|ensembl:ENST00000399113(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045202"(synapse)|go:"GO:0099536"(synaptic signaling)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR017432(Distrobrevin)|interpro:IPR043145|mint:Q9Y4J8|rcsb pdb:2E5R|interpro:IPR000433(Zinc finger, ZZ-type)|refseq:NP_001185873.1|refseq:NP_001381.2|refseq:NP_001382.2|refseq:NP_001383.2|refseq:NP_116757.2|refseq:NP_116760.2|refseq:NP_116761.2|refseq:NP_116762.2|refseq:NP_116763.1|refseq:XP_011524155.1|refseq:NP_001121647.1|refseq:NP_001185867.1|refseq:NP_001185868.1|refseq:NP_001185871.1|refseq:NP_001185869.1|refseq:NP_001185874.1|refseq:NP_001185870.1|refseq:XP_016881066.1|refseq:XP_016881073.1|refseq:XP_016881076.1|refseq:XP_016881077.1|refseq:XP_016881078.1|refseq:XP_016881079.1|refseq:XP_016881080.1|refseq:XP_016881089.1|refseq:XP_016881090.1|refseq:XP_016881091.1|mint:MINT-577466(identity) - comment:mint|function:"Desmuslin is a type-VI intermediate filament which may function as a mechanical support to the muscle fibers by making a linkage between the extracellular matrix via the dystrophin-associated protein complex (DAPC) and the Z-disk"|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:homomint|comment:mint taxid:-4(in vivo)|taxid:-4(in vivo) - 2001/08/30 2014/10/16 rogid:rzVhqnzGeDs2F13p1f2TSKoradM9606 rogid:9HaDKLthoXmwdYDzbEer3CRN3O09606 intact-crc:8A6512C7AA92FB3E|rigid:aKLJsX6MVJOZXyYFMfc6Y8TLEeU false tag:?-?(MINT-577461)|binding-associated region:1-337(MINT-577459) tag:?-?(MINT-577467) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O15061 uniprotkb:Q9Y4J8 intact:EBI-7843148|intact:EBI-28977600|ensembl:ENSP00000336775|intact:MINT-198289|uniprotkb:Q2TBJ4|uniprotkb:Q5NJJ9|uniprotkb:Q8TE62|uniprotkb:A7E2Y2|uniprotkb:Q8TE61 intact:EBI-949471|ensembl:ENSP00000382064|uniprotkb:O15332|uniprotkb:O15333|uniprotkb:O75697|uniprotkb:Q13197|uniprotkb:Q13198|uniprotkb:Q13199|uniprotkb:Q13498|uniprotkb:Q13499|uniprotkb:Q13500|uniprotkb:A8MUY4|uniprotkb:A8K541|uniprotkb:M0QYX6|uniprotkb:A8MSZ0|uniprotkb:Q9BS59|uniprotkb:B4DIU8|uniprotkb:B4DIR0|uniprotkb:B4DGS6|uniprotkb:M0R397|uniprotkb:Q59GK7 psi-mi:synem_human(display_long)|uniprotkb:KIAA0353(gene name synonym)|uniprotkb:DMN(gene name synonym)|uniprotkb:SYN(gene name synonym)|uniprotkb:Desmuslin(gene name synonym)|uniprotkb:SYNM(gene name)|psi-mi:SYNM(display_short) psi-mi:dtna_human(display_long)|uniprotkb:Alpha-dystrobrevin(gene name synonym)|uniprotkb:Dystrophin-related protein 3(gene name synonym)|uniprotkb:DTNA(gene name)|psi-mi:DTNA(display_short)|uniprotkb:DRP3(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Mizuno et al. (2001) pubmed:11353857|mint:MINT-5214016 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7843225|mint:MINT-18685 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000336775|ensembl:ENSG00000182253(gene)|ensembl:ENST00000336292(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005912"(adherens junction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017166"(vinculin binding)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0031443"(fast-twitch skeletal muscle fiber contraction)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0060053"(neurofilament cytoskeleton)|interpro:IPR018039|interpro:IPR030634|interpro:IPR039008|rcsb pdb:6EWO|refseq:NP_056101.5|refseq:NP_663780.2|mint:MINT-577477(identity) ensembl:ENSG00000134769(gene)|ensembl:ENST00000399113(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045202"(synapse)|go:"GO:0099536"(synaptic signaling)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR017432(Distrobrevin)|interpro:IPR043145|mint:Q9Y4J8|rcsb pdb:2E5R|interpro:IPR000433(Zinc finger, ZZ-type)|refseq:NP_001185873.1|refseq:NP_001381.2|refseq:NP_001382.2|refseq:NP_001383.2|refseq:NP_116757.2|refseq:NP_116760.2|refseq:NP_116761.2|refseq:NP_116762.2|refseq:NP_116763.1|refseq:XP_011524155.1|refseq:NP_001121647.1|refseq:NP_001185867.1|refseq:NP_001185868.1|refseq:NP_001185871.1|refseq:NP_001185869.1|refseq:NP_001185874.1|refseq:NP_001185870.1|refseq:XP_016881066.1|refseq:XP_016881073.1|refseq:XP_016881076.1|refseq:XP_016881077.1|refseq:XP_016881078.1|refseq:XP_016881079.1|refseq:XP_016881080.1|refseq:XP_016881089.1|refseq:XP_016881090.1|refseq:XP_016881091.1|mint:MINT-577482(identity) - comment:mint|function:"Desmuslin is a type-VI intermediate filament which may function as a mechanical support to the muscle fibers by making a linkage between the extracellular matrix via the dystrophin-associated protein complex (DAPC) and the Z-disk"|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:homomint|comment:mint taxid:-4(in vivo)|taxid:-4(in vivo) - 2001/08/30 2014/10/16 rogid:rzVhqnzGeDs2F13p1f2TSKoradM9606 rogid:9HaDKLthoXmwdYDzbEer3CRN3O09606 intact-crc:97D8AAB6D0EF44C9|rigid:aKLJsX6MVJOZXyYFMfc6Y8TLEeU false binding-associated region:1-337(MINT-577478) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)