#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P20942 uniprotkb:P63102 intact:EBI-7817483|ensembl:ENSRNOP00000003405|uniprotkb:Q63420|intact:MINT-197623 intact:EBI-354758|uniprotkb:P35215|uniprotkb:P70197|uniprotkb:P97286|uniprotkb:Q52KK1|uniprotkb:Q6IRF4|ensembl:ENSRNOP00000030885 psi-mi:phos_rat(display_long)|uniprotkb:Pdc(gene name)|psi-mi:Pdc(display_short)|uniprotkb:Rpr1(gene name synonym)|uniprotkb:33 kDa phototransducing protein(gene name synonym)|uniprotkb:Rod photoreceptor 1(gene name synonym)|uniprotkb:Protein MEKA(gene name synonym) psi-mi:1433z_rat(display_long)|uniprotkb:Ywhaz(gene name)|psi-mi:Ywhaz(display_short)|uniprotkb:Msfs1(gene name synonym)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Mitochondrial import stimulation factor S1 subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Thulin et al. (2001) pubmed:11331285|mint:MINT-5213980 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7834641|mint:MINT-15791 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000002517(gene)|ensembl:ENSRNOT00000003405(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0050896"(response to stimulus)|interpro:IPR001200(Phosducin)|interpro:IPR023196|interpro:IPR024253|interpro:IPR036249|rcsb pdb:1B9X|rcsb pdb:1B9Y|rcsb pdb:2TRC|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|refseq:NP_037004.1|rgd:3277|dip:DIP-41816N|mint:MINT-576764(identity) rgd:3980|refseq:NP_037143.2|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031252"(cell leading edge)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035148"(tube formation)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P63102|reactome:R-RNO-111447|reactome:R-RNO-3769402|reactome:R-RNO-392517|reactome:R-RNO-430116|reactome:R-RNO-450604|reactome:R-RNO-512988|reactome:R-RNO-5625740|reactome:R-RNO-5628897|reactome:R-RNO-75035|reactome:R-RNO-9013700|reactome:R-RNO-9614399|refseq:XP_006241591.1|ensembl:ENSRNOG00000008195(gene)|ensembl:ENSRNOT00000035628(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002553"(histamine secretion by mast cell)|go:"GO:0003016"(respiratory system process)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|dip:DIP-36916N|mint:MINT-576781(identity) - comment:mint|function:May participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:14-3-3 binds phosphorylated Pd and and sequester Dp from G protein subunits beta and gamma.|comment:mint|partial coverage:partial coverage|curation depth:rapid curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2001/09/24 2014/10/16 rogid:QO5d+BZRM1IUD0HJyVWu4gqcaM410116 rogid:v2N95HO8sYRWEg2gFtWiYajP1Sc10116 intact-crc:59BF42AEC149F30C|rigid:V0mfWndvofq/3RaS/eaFRyHcwA0 false O-phospho-L-serine:106-106(MINT-576777)|O-phospho-L-serine:73-73(MINT-576775)|O-phospho-L-serine:36-36(MINT-576771)|O-phospho-L-serine:6-6(MINT-576769)|binding-associated region:51-75(MINT-576765)|O-phospho-L-serine:54-54(MINT-576773) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62261 uniprotkb:P20942 intact:EBI-7817644|ensembl:ENSBTAP00000007442|uniprotkb:P29360|uniprotkb:Q63631|uniprotkb:Q3ZC40|intact:UNK-6045163|uniprotkb:P42655 intact:EBI-7817483|ensembl:ENSRNOP00000003405|uniprotkb:Q63420|intact:MINT-197623 psi-mi:1433e_bovin(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short) psi-mi:phos_rat(display_long)|uniprotkb:Pdc(gene name)|psi-mi:Pdc(display_short)|uniprotkb:Rpr1(gene name synonym)|uniprotkb:33 kDa phototransducing protein(gene name synonym)|uniprotkb:Rod photoreceptor 1(gene name synonym)|uniprotkb:Protein MEKA(gene name synonym) psi-mi:"MI:0096"(pull down) Thulin et al. (2001) pubmed:11331285|mint:MINT-5213980 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7834687|mint:MINT-8005601 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000005664(gene)|ensembl:ENSBTAT00000007442(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042470"(melanosome)|go:"GO:0046827"(positive regulation of protein export from nucleus)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|refseq:NP_776916.1|mint:MINT-8005602(identity)|uniprotkb:P62261(original identifier) ensembl:ENSRNOG00000002517(gene)|ensembl:ENSRNOT00000003405(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0050896"(response to stimulus)|interpro:IPR001200(Phosducin)|interpro:IPR023196|interpro:IPR024253|interpro:IPR036249|rcsb pdb:1B9X|rcsb pdb:1B9Y|rcsb pdb:2TRC|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|refseq:NP_037004.1|rgd:3277|dip:DIP-41816N|mint:MINT-8005605(identity)|uniprotkb:P20942(original identifier) - function:Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner|comment:mint comment:mint|function:May participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage|curation depth:rapid curation taxid:-3(unknown)|taxid:-3(Unknown) - 2001/09/24 2014/10/16 rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9913 rogid:QO5d+BZRM1IUD0HJyVWu4gqcaM410116 intact-crc:CCFF431DE10E125C|rigid:GmK35ccSlzBVxPNNUl6JgSGKOwk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62261 uniprotkb:P20942 intact:EBI-7817644|ensembl:ENSBTAP00000007442|uniprotkb:P29360|uniprotkb:Q63631|uniprotkb:Q3ZC40|intact:UNK-6045163|uniprotkb:P42655 intact:EBI-7817483|ensembl:ENSRNOP00000003405|uniprotkb:Q63420|intact:MINT-197623 psi-mi:1433e_bovin(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short) psi-mi:phos_rat(display_long)|uniprotkb:Pdc(gene name)|psi-mi:Pdc(display_short)|uniprotkb:Rpr1(gene name synonym)|uniprotkb:33 kDa phototransducing protein(gene name synonym)|uniprotkb:Rod photoreceptor 1(gene name synonym)|uniprotkb:Protein MEKA(gene name synonym) psi-mi:"MI:0096"(pull down) Thulin et al. (2001) pubmed:11331285|mint:MINT-5213980 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7834700|mint:MINT-8005608 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000005664(gene)|ensembl:ENSBTAT00000007442(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042470"(melanosome)|go:"GO:0046827"(positive regulation of protein export from nucleus)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|refseq:NP_776916.1|mint:MINT-8005609(identity)|uniprotkb:P62261(original identifier) ensembl:ENSRNOG00000002517(gene)|ensembl:ENSRNOT00000003405(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0050896"(response to stimulus)|interpro:IPR001200(Phosducin)|interpro:IPR023196|interpro:IPR024253|interpro:IPR036249|rcsb pdb:1B9X|rcsb pdb:1B9Y|rcsb pdb:2TRC|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|refseq:NP_037004.1|rgd:3277|dip:DIP-41816N|mint:MINT-8005612(identity)|uniprotkb:P20942(original identifier) - function:Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner|comment:mint comment:mint|function:May participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage|curation depth:rapid curation taxid:-3(unknown)|taxid:-3(Unknown) - 2001/09/24 2014/10/16 rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9913 rogid:QO5d+BZRM1IUD0HJyVWu4gqcaM410116 intact-crc:69350D085886A690|rigid:GmK35ccSlzBVxPNNUl6JgSGKOwk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)