#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q6P5Z2 uniprotkb:Q13393 intact:EBI-1384335|uniprotkb:Q9UM03|ensembl:ENSP00000291906 intact:EBI-2827556|ensembl:ENSP00000342793 psi-mi:pkn3_human(display_long)|uniprotkb:PKNBETA(gene name synonym)|uniprotkb:Protein kinase PKN-beta(gene name synonym)|uniprotkb:Protein-kinase C-related kinase 3(gene name synonym)|uniprotkb:PKN3(gene name)|psi-mi:PKN3(display_short) psi-mi:pld1_human(display_long)|uniprotkb:PLD1(gene name)|psi-mi:PLD1(display_short)|uniprotkb:Choline phosphatase 1(gene name synonym)|uniprotkb:Phosphatidylcholine-hydrolyzing phospholipase D1(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Oishi et al. (2001) pubmed:11259428|mint:MINT-5213735 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7796971|mint:MINT-15998 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037487.2|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR035892|interpro:IPR036274|interpro:IPR037313|reactome:R-HSA-5625740|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000160447(gene)|ensembl:ENST00000291906(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0010631"(epithelial cell migration)|mint:MINT-470214(identity) refseq:XP_011511199.1|refseq:NP_002653.1|ensembl:ENSG00000075651(gene)|ensembl:ENST00000351298(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004630"(phospholipase D activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048870"(cell motility)|go:"GO:0070290"(N-acylphosphatidylethanolamine-specific phospholipase D activity)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098981"(cholinergic synapse)|interpro:IPR001683(Phox-like)|interpro:IPR001736(Phospholipase D/Transphosphatidylase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015679(Phospholipase D)|interpro:IPR016555(Phospholipase D, eukaryota)|interpro:IPR025202|interpro:IPR036871|mint:Q13393|rcsb pdb:6U8Z|reactome:R-HSA-1483148|reactome:R-HSA-1483166|reactome:R-HSA-2029485|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|refseq:XP_005247590.1|refseq:XP_005247591.1|dip:DIP-40821N|mint:MINT-470217(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:homomint|comment:mint taxid:-4(in vivo)|taxid:-4(in vivo) - 2001/03/30 2014/10/16 rogid:VkdWW9BW24I/9AWyh6wP5u1MRCA9606 rogid:4TlTbVJTGGyEAcq/Gby1STgUH4Q9606 intact-crc:F7B74F540E0A0A1D|rigid:9zUlTK6RfwQj71BHuNXMuAK10Tg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6P5Z2 uniprotkb:Q13393 intact:EBI-1384335|uniprotkb:Q9UM03|ensembl:ENSP00000291906 intact:EBI-2827556|ensembl:ENSP00000342793 psi-mi:pkn3_human(display_long)|uniprotkb:PKNBETA(gene name synonym)|uniprotkb:Protein kinase PKN-beta(gene name synonym)|uniprotkb:Protein-kinase C-related kinase 3(gene name synonym)|uniprotkb:PKN3(gene name)|psi-mi:PKN3(display_short) psi-mi:pld1_human(display_long)|uniprotkb:PLD1(gene name)|psi-mi:PLD1(display_short)|uniprotkb:Choline phosphatase 1(gene name synonym)|uniprotkb:Phosphatidylcholine-hydrolyzing phospholipase D1(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Oishi et al. (2001) pubmed:11259428|mint:MINT-5213735 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7796981|mint:MINT-15997 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037487.2|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR035892|interpro:IPR036274|interpro:IPR037313|reactome:R-HSA-5625740|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000160447(gene)|ensembl:ENST00000291906(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0010631"(epithelial cell migration)|mint:MINT-470232(identity) refseq:XP_011511199.1|refseq:NP_002653.1|ensembl:ENSG00000075651(gene)|ensembl:ENST00000351298(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004630"(phospholipase D activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048870"(cell motility)|go:"GO:0070290"(N-acylphosphatidylethanolamine-specific phospholipase D activity)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098981"(cholinergic synapse)|interpro:IPR001683(Phox-like)|interpro:IPR001736(Phospholipase D/Transphosphatidylase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015679(Phospholipase D)|interpro:IPR016555(Phospholipase D, eukaryota)|interpro:IPR025202|interpro:IPR036871|mint:Q13393|rcsb pdb:6U8Z|reactome:R-HSA-1483148|reactome:R-HSA-1483166|reactome:R-HSA-2029485|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|refseq:XP_005247590.1|refseq:XP_005247591.1|dip:DIP-40821N|mint:MINT-470235(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:homomint|comment:mint taxid:-4(in vivo)|taxid:-4(in vivo) - 2001/03/30 2014/10/16 rogid:VkdWW9BW24I/9AWyh6wP5u1MRCA9606 rogid:4TlTbVJTGGyEAcq/Gby1STgUH4Q9606 intact-crc:0BD73C1A8033EC4D|rigid:9zUlTK6RfwQj71BHuNXMuAK10Tg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6P5Z2 uniprotkb:Q13393 intact:EBI-1384335|uniprotkb:Q9UM03|ensembl:ENSP00000291906 intact:EBI-2827556|ensembl:ENSP00000342793 psi-mi:pkn3_human(display_long)|uniprotkb:PKNBETA(gene name synonym)|uniprotkb:Protein kinase PKN-beta(gene name synonym)|uniprotkb:Protein-kinase C-related kinase 3(gene name synonym)|uniprotkb:PKN3(gene name)|psi-mi:PKN3(display_short) psi-mi:pld1_human(display_long)|uniprotkb:PLD1(gene name)|psi-mi:PLD1(display_short)|uniprotkb:Choline phosphatase 1(gene name synonym)|uniprotkb:Phosphatidylcholine-hydrolyzing phospholipase D1(gene name synonym) psi-mi:"MI:0096"(pull down) Oishi et al. (2001) pubmed:11259428|mint:MINT-5213735 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7796999|mint:MINT-15999 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037487.2|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR035892|interpro:IPR036274|interpro:IPR037313|reactome:R-HSA-5625740|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000160447(gene)|ensembl:ENST00000291906(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0010631"(epithelial cell migration)|mint:MINT-470224(identity) refseq:XP_011511199.1|refseq:NP_002653.1|ensembl:ENSG00000075651(gene)|ensembl:ENST00000351298(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004630"(phospholipase D activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048870"(cell motility)|go:"GO:0070290"(N-acylphosphatidylethanolamine-specific phospholipase D activity)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098981"(cholinergic synapse)|interpro:IPR001683(Phox-like)|interpro:IPR001736(Phospholipase D/Transphosphatidylase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015679(Phospholipase D)|interpro:IPR016555(Phospholipase D, eukaryota)|interpro:IPR025202|interpro:IPR036871|mint:Q13393|rcsb pdb:6U8Z|reactome:R-HSA-1483148|reactome:R-HSA-1483166|reactome:R-HSA-2029485|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|refseq:XP_005247590.1|refseq:XP_005247591.1|dip:DIP-40821N|mint:MINT-470227(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2001/03/30 2014/10/16 rogid:VkdWW9BW24I/9AWyh6wP5u1MRCA9606 rogid:4TlTbVJTGGyEAcq/Gby1STgUH4Q9606 intact-crc:41D7B0316D457D3B|rigid:9zUlTK6RfwQj71BHuNXMuAK10Tg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)