#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P34709	uniprotkb:P34708	intact:EBI-367223|uniprotkb:Q8STA8|uniprotkb:Q8STE2|uniprotkb:Q8T5X5|uniprotkb:Q8T5X6|uniprotkb:Q8T5X7|uniprotkb:Q8T5X8|uniprotkb:Q8T5X9|uniprotkb:Q8T5Y0|uniprotkb:Q8T5Y1|uniprotkb:Q8T5Y2|uniprotkb:Q8T5Y3|uniprotkb:Q8T5Y4|uniprotkb:Q8T5Y5|uniprotkb:Q9N5Y5|ensemblmetazoa:C15F1.3a.1	intact:EBI-367204|uniprotkb:Q95Q22|uniprotkb:Q9U2C0|ensemblmetazoa:Y47D3A.6a.1	psi-mi:tra2_caeel(display_long)|uniprotkb:tra-2(gene name)|psi-mi:tra-2(display_short)|uniprotkb:C15F1.3(orf name)|uniprotkb:Ce-Tra-2(gene name synonym)	psi-mi:tra1_caeel(display_long)|uniprotkb:tra-1(gene name)|psi-mi:tra-1(display_short)|uniprotkb:her-2(gene name synonym)|uniprotkb:Y47D3A.6(orf name)|uniprotkb:Hermaphrodization of XO animals protein 2(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Lum et al. (2000)	pubmed:11124807|mint:MINT-5213336	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-640637	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001021954.1|refseq:NP_495426.1|wormbase:C15F1.3a|wormbase:C15F1.3b|interpro:IPR032848|ensemblmetazoa:C15F1.3a.1(transcript)|ensemblmetazoa:WBGene00006605(gene)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007530"(sex determination)|go:"GO:0007548"(sex differentiation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018992"(germ-line sex determination)|go:"GO:0030154"(cell differentiation)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040021"(hermaphrodite germ-line sex determination)|go:"GO:0042001"(hermaphrodite somatic sex determination)|go:"GO:0044214"(spanning component of plasma membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)	wormbase:Y47D3A.6a|wormbase:Y47D3A.6b|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|ensemblmetazoa:WBGene00006604(gene)|ensemblmetazoa:Y47D3A.6a.1(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008406"(gonad development)|go:"GO:0019099"(female germ-line sex determination)|go:"GO:0030154"(cell differentiation)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0019101"(female somatic sex determination)|interpro:IPR036236	-	-	-	-	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	-	2001/01/24	2014/10/16	rogid:AfAwcrMV8QNzg5YkaaGyPHuWPow6239	rogid:68IEYezaTV2jJDkpyyxTmNIzA6w6239	intact-crc:E8EDFB0BD60240C6|rigid:6MsetpOUcz0fgF2I+34owklLwEY	false	35s radiolabel:?-?|binding-associated region:1272-1475	myc tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P34708	uniprotkb:P34709	intact:EBI-367204|uniprotkb:Q95Q22|uniprotkb:Q9U2C0|ensemblmetazoa:Y47D3A.6a.1	intact:EBI-367223|uniprotkb:Q8STA8|uniprotkb:Q8STE2|uniprotkb:Q8T5X5|uniprotkb:Q8T5X6|uniprotkb:Q8T5X7|uniprotkb:Q8T5X8|uniprotkb:Q8T5X9|uniprotkb:Q8T5Y0|uniprotkb:Q8T5Y1|uniprotkb:Q8T5Y2|uniprotkb:Q8T5Y3|uniprotkb:Q8T5Y4|uniprotkb:Q8T5Y5|uniprotkb:Q9N5Y5|ensemblmetazoa:C15F1.3a.1	psi-mi:tra1_caeel(display_long)|uniprotkb:tra-1(gene name)|psi-mi:tra-1(display_short)|uniprotkb:her-2(gene name synonym)|uniprotkb:Y47D3A.6(orf name)|uniprotkb:Hermaphrodization of XO animals protein 2(gene name synonym)	psi-mi:tra2_caeel(display_long)|uniprotkb:tra-2(gene name)|psi-mi:tra-2(display_short)|uniprotkb:C15F1.3(orf name)|uniprotkb:Ce-Tra-2(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Lum et al. (2000)	pubmed:11124807|mint:MINT-5213336	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-640680	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	wormbase:Y47D3A.6a|wormbase:Y47D3A.6b|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|ensemblmetazoa:WBGene00006604(gene)|ensemblmetazoa:Y47D3A.6a.1(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008406"(gonad development)|go:"GO:0019099"(female germ-line sex determination)|go:"GO:0030154"(cell differentiation)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0019101"(female somatic sex determination)|interpro:IPR036236	refseq:NP_001021954.1|refseq:NP_495426.1|wormbase:C15F1.3a|wormbase:C15F1.3b|interpro:IPR032848|ensemblmetazoa:C15F1.3a.1(transcript)|ensemblmetazoa:WBGene00006605(gene)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007530"(sex determination)|go:"GO:0007548"(sex differentiation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018992"(germ-line sex determination)|go:"GO:0030154"(cell differentiation)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040021"(hermaphrodite germ-line sex determination)|go:"GO:0042001"(hermaphrodite somatic sex determination)|go:"GO:0044214"(spanning component of plasma membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)	-	-	-	comment:Point mutations in the MX region of tra2 severely disrupt the tra2-tra1 interaction.	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	-	2001/01/24	2014/10/16	rogid:68IEYezaTV2jJDkpyyxTmNIzA6w6239	rogid:AfAwcrMV8QNzg5YkaaGyPHuWPow6239	intact-crc:0774FE4EF0D72BF3|rigid:6MsetpOUcz0fgF2I+34owklLwEY	false	myc tag:?-?	35s radiolabel:?-?|mutation decreasing interaction:1393-1393,1401-1401,1394-1394	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P34708	uniprotkb:P34709	intact:EBI-367204|uniprotkb:Q95Q22|uniprotkb:Q9U2C0|ensemblmetazoa:Y47D3A.6a.1	intact:EBI-367223|uniprotkb:Q8STA8|uniprotkb:Q8STE2|uniprotkb:Q8T5X5|uniprotkb:Q8T5X6|uniprotkb:Q8T5X7|uniprotkb:Q8T5X8|uniprotkb:Q8T5X9|uniprotkb:Q8T5Y0|uniprotkb:Q8T5Y1|uniprotkb:Q8T5Y2|uniprotkb:Q8T5Y3|uniprotkb:Q8T5Y4|uniprotkb:Q8T5Y5|uniprotkb:Q9N5Y5|ensemblmetazoa:C15F1.3a.1	psi-mi:tra1_caeel(display_long)|uniprotkb:tra-1(gene name)|psi-mi:tra-1(display_short)|uniprotkb:her-2(gene name synonym)|uniprotkb:Y47D3A.6(orf name)|uniprotkb:Hermaphrodization of XO animals protein 2(gene name synonym)	psi-mi:tra2_caeel(display_long)|uniprotkb:tra-2(gene name)|psi-mi:tra-2(display_short)|uniprotkb:C15F1.3(orf name)|uniprotkb:Ce-Tra-2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Lum et al. (2000)	pubmed:11124807|mint:MINT-5213336	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-640652	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	wormbase:Y47D3A.6a|wormbase:Y47D3A.6b|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|ensemblmetazoa:WBGene00006604(gene)|ensemblmetazoa:Y47D3A.6a.1(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008406"(gonad development)|go:"GO:0019099"(female germ-line sex determination)|go:"GO:0030154"(cell differentiation)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0019101"(female somatic sex determination)|interpro:IPR036236	refseq:NP_001021954.1|refseq:NP_495426.1|wormbase:C15F1.3a|wormbase:C15F1.3b|interpro:IPR032848|ensemblmetazoa:C15F1.3a.1(transcript)|ensemblmetazoa:WBGene00006605(gene)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007530"(sex determination)|go:"GO:0007548"(sex differentiation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018992"(germ-line sex determination)|go:"GO:0030154"(cell differentiation)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040021"(hermaphrodite germ-line sex determination)|go:"GO:0042001"(hermaphrodite somatic sex determination)|go:"GO:0044214"(spanning component of plasma membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)	-	-	-	comment:"Confirms binding between the c-terminus of tra2 (AA 1272-1475) with the c-terminus of tra1 (AA 663-843)."	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2001/01/24	2014/10/16	rogid:68IEYezaTV2jJDkpyyxTmNIzA6w6239	rogid:AfAwcrMV8QNzg5YkaaGyPHuWPow6239	intact-crc:D14DEE106F7A7C68|rigid:6MsetpOUcz0fgF2I+34owklLwEY	false	binding-associated region:663-843	binding-associated region:1272-1475	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P34708	uniprotkb:P34709	intact:EBI-367204|uniprotkb:Q95Q22|uniprotkb:Q9U2C0|ensemblmetazoa:Y47D3A.6a.1	intact:EBI-367223|uniprotkb:Q8STA8|uniprotkb:Q8STE2|uniprotkb:Q8T5X5|uniprotkb:Q8T5X6|uniprotkb:Q8T5X7|uniprotkb:Q8T5X8|uniprotkb:Q8T5X9|uniprotkb:Q8T5Y0|uniprotkb:Q8T5Y1|uniprotkb:Q8T5Y2|uniprotkb:Q8T5Y3|uniprotkb:Q8T5Y4|uniprotkb:Q8T5Y5|uniprotkb:Q9N5Y5|ensemblmetazoa:C15F1.3a.1	psi-mi:tra1_caeel(display_long)|uniprotkb:tra-1(gene name)|psi-mi:tra-1(display_short)|uniprotkb:her-2(gene name synonym)|uniprotkb:Y47D3A.6(orf name)|uniprotkb:Hermaphrodization of XO animals protein 2(gene name synonym)	psi-mi:tra2_caeel(display_long)|uniprotkb:tra-2(gene name)|psi-mi:tra-2(display_short)|uniprotkb:C15F1.3(orf name)|uniprotkb:Ce-Tra-2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Lum et al. (2000)	pubmed:11124807|mint:MINT-5213336	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-640700	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	wormbase:Y47D3A.6a|wormbase:Y47D3A.6b|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|ensemblmetazoa:WBGene00006604(gene)|ensemblmetazoa:Y47D3A.6a.1(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008406"(gonad development)|go:"GO:0019099"(female germ-line sex determination)|go:"GO:0030154"(cell differentiation)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0019101"(female somatic sex determination)|interpro:IPR036236	refseq:NP_001021954.1|refseq:NP_495426.1|wormbase:C15F1.3a|wormbase:C15F1.3b|interpro:IPR032848|ensemblmetazoa:C15F1.3a.1(transcript)|ensemblmetazoa:WBGene00006605(gene)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007530"(sex determination)|go:"GO:0007548"(sex differentiation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018992"(germ-line sex determination)|go:"GO:0030154"(cell differentiation)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040021"(hermaphrodite germ-line sex determination)|go:"GO:0042001"(hermaphrodite somatic sex determination)|go:"GO:0044214"(spanning component of plasma membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)	-	-	-	comment:The mutation leu723phe within tra1 prevents its' binding to tra2 whereas the thre749ile mutation did not affect the tra1-tra2 interaction.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2001/01/24	2014/10/16	rogid:68IEYezaTV2jJDkpyyxTmNIzA6w6239	rogid:AfAwcrMV8QNzg5YkaaGyPHuWPow6239	intact-crc:C2BB80C965065771|rigid:6MsetpOUcz0fgF2I+34owklLwEY	false	binding-associated region:663-1011|mutation decreasing interaction:723-723	binding-associated region:1272-1475	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P34709	uniprotkb:P34691	intact:EBI-367223|uniprotkb:Q8STA8|uniprotkb:Q8STE2|uniprotkb:Q8T5X5|uniprotkb:Q8T5X6|uniprotkb:Q8T5X7|uniprotkb:Q8T5X8|uniprotkb:Q8T5X9|uniprotkb:Q8T5Y0|uniprotkb:Q8T5Y1|uniprotkb:Q8T5Y2|uniprotkb:Q8T5Y3|uniprotkb:Q8T5Y4|uniprotkb:Q8T5Y5|uniprotkb:Q9N5Y5|ensemblmetazoa:C15F1.3a.1	intact:EBI-445465|ensemblmetazoa:C01F6.4a.1	psi-mi:tra2_caeel(display_long)|uniprotkb:tra-2(gene name)|psi-mi:tra-2(display_short)|uniprotkb:C15F1.3(orf name)|uniprotkb:Ce-Tra-2(gene name synonym)	psi-mi:fem3_caeel(display_long)|uniprotkb:Feminization of XX and XO animals protein 3(gene name synonym)|uniprotkb:Ce-FEM-3(gene name synonym)|uniprotkb:C01F6.4(orf name)|uniprotkb:fem-3(gene name)|psi-mi:fem-3(display_short)	psi-mi:"MI:0018"(two hybrid)	Lum et al. (2000)	pubmed:11124807|mint:MINT-5213336	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-641478	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001021954.1|refseq:NP_495426.1|wormbase:C15F1.3a|wormbase:C15F1.3b|interpro:IPR032848|ensemblmetazoa:C15F1.3a.1(transcript)|ensemblmetazoa:WBGene00006605(gene)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007530"(sex determination)|go:"GO:0007548"(sex differentiation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018992"(germ-line sex determination)|go:"GO:0030154"(cell differentiation)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040021"(hermaphrodite germ-line sex determination)|go:"GO:0042001"(hermaphrodite somatic sex determination)|go:"GO:0044214"(spanning component of plasma membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)	ensemblmetazoa:C01F6.4a.1(transcript)|ensemblmetazoa:WBGene00001413(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007548"(sex differentiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030238"(male sex determination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043406"(positive regulation of MAP kinase activity)|interpro:IPR030804|refseq:NP_001255365.1|wormbase:C01F6.4a|go:"GO:0060282"(positive regulation of oocyte development)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1904146"(positive regulation of meiotic cell cycle process involved in oocyte maturation)|go:"GO:1905936"(regulation of germ cell proliferation)	-	-	-	comment:"Confirms interaction between the smallest fragment of tra2 (AA 1133-1272) and fem3."	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2001/01/24	2014/10/16	rogid:AfAwcrMV8QNzg5YkaaGyPHuWPow6239	rogid:3WeE4VQ4oQC4FjKX7mUkJ/kWfGo6239	intact-crc:FDB49F750DEFA8C0|rigid:Qlw8a14/78jUGPiqsQd3XGc4ju0	false	binding-associated region:1133-1272	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P34709	uniprotkb:P34708	intact:EBI-367223|uniprotkb:Q8STA8|uniprotkb:Q8STE2|uniprotkb:Q8T5X5|uniprotkb:Q8T5X6|uniprotkb:Q8T5X7|uniprotkb:Q8T5X8|uniprotkb:Q8T5X9|uniprotkb:Q8T5Y0|uniprotkb:Q8T5Y1|uniprotkb:Q8T5Y2|uniprotkb:Q8T5Y3|uniprotkb:Q8T5Y4|uniprotkb:Q8T5Y5|uniprotkb:Q9N5Y5|ensemblmetazoa:C15F1.3a.1	intact:EBI-367204|uniprotkb:Q95Q22|uniprotkb:Q9U2C0|ensemblmetazoa:Y47D3A.6a.1	psi-mi:tra2_caeel(display_long)|uniprotkb:tra-2(gene name)|psi-mi:tra-2(display_short)|uniprotkb:C15F1.3(orf name)|uniprotkb:Ce-Tra-2(gene name synonym)	psi-mi:tra1_caeel(display_long)|uniprotkb:tra-1(gene name)|psi-mi:tra-1(display_short)|uniprotkb:her-2(gene name synonym)|uniprotkb:Y47D3A.6(orf name)|uniprotkb:Hermaphrodization of XO animals protein 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Lum et al. (2000)	pubmed:11124807|mint:MINT-5213336	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-641498	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001021954.1|refseq:NP_495426.1|wormbase:C15F1.3a|wormbase:C15F1.3b|interpro:IPR032848|ensemblmetazoa:C15F1.3a.1(transcript)|ensemblmetazoa:WBGene00006605(gene)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007530"(sex determination)|go:"GO:0007548"(sex differentiation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018992"(germ-line sex determination)|go:"GO:0030154"(cell differentiation)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040021"(hermaphrodite germ-line sex determination)|go:"GO:0042001"(hermaphrodite somatic sex determination)|go:"GO:0044214"(spanning component of plasma membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)	wormbase:Y47D3A.6a|wormbase:Y47D3A.6b|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|ensemblmetazoa:WBGene00006604(gene)|ensemblmetazoa:Y47D3A.6a.1(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008406"(gonad development)|go:"GO:0019099"(female germ-line sex determination)|go:"GO:0030154"(cell differentiation)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0019101"(female somatic sex determination)|interpro:IPR036236	-	-	-	comment:The point mutations within the tra-2 mx region inhibited its' interaction with tra-1 but did not interfere with its ability to interact with fem-3.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2001/01/24	2014/10/16	rogid:AfAwcrMV8QNzg5YkaaGyPHuWPow6239	rogid:68IEYezaTV2jJDkpyyxTmNIzA6w6239	intact-crc:681AD66C97BB70A1|rigid:6MsetpOUcz0fgF2I+34owklLwEY	false	binding-associated region:1133-1475|mutation decreasing interaction:1392-1392,1400-1400,1393-1393	binding-associated region:663-1011	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)