#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P17106 uniprotkb:P35201 intact:EBI-4096|uniprotkb:Q6Q5N1|uniprotkb:P17623|uniprotkb:D6VWN1|ensemblfungi:YJR060W intact:EBI-10908|ensemblfungi:YKL089W|uniprotkb:D6VXJ9 psi-mi:cbf1_yeast(display_long)|uniprotkb:CEP1(gene name synonym)|uniprotkb:CP1(gene name synonym)|uniprotkb:CPF1(gene name synonym)|uniprotkb:J1730(orf name)|uniprotkb:YJR060W(locus name)|uniprotkb:CBF1(gene name)|psi-mi:CBF1(display_short)|uniprotkb:Centromere-binding factor 1(gene name synonym)|uniprotkb:Centromere promoter factor 1(gene name synonym) psi-mi:cenpc_yeast(display_long)|uniprotkb:MIF2(gene name)|psi-mi:MIF2(display_short)|uniprotkb:CENP-C homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein MIF2(gene name synonym)|uniprotkb:Mitotic fidelity of chromosome transmission protein 2(gene name synonym)|uniprotkb:YKL089W(locus name) psi-mi:"MI:0096"(pull down) Hemmerich et al. (2000) pubmed:11070082|mint:MINT-5213167 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7436210|mint:MINT-16430 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012594.1|sgd:S000003821|dip:DIP-2239N|mint:P17106|ensemblfungi:YJR060W(gene)|ensemblfungi:YJR060W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0089713"(Cbf1-Met4-Met28 complex)|go:"GO:0098781"(ncRNA transcription)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:MINT-433595(identity) ensemblfungi:YKL089W(gene)|ensemblfungi:YKL089W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR025974|interpro:IPR028386|interpro:IPR028929|rcsb pdb:2VPV|rcsb pdb:6QLD|go:"GO:0000779"(condensed chromosome, centromeric region)|refseq:NP_012834.1|sgd:S000001572|dip:DIP-7297N|mint:MINT-433598(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2001/06/23 2014/10/16 rogid:SjrIzQ9f1rrxeycid/060/5MRY8559292 rogid:lDQV5PvH8wpTMYTGj9iH0W1S7ok559292 intact-crc:518DCD74847F3FEC|rigid:yWnw/oU9emb26KLsIjQ8lNERvlo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40969 uniprotkb:P17106 intact:EBI-4077|uniprotkb:D6VZZ0|ensemblfungi:YMR168C intact:EBI-4096|uniprotkb:Q6Q5N1|uniprotkb:P17623|uniprotkb:D6VWN1|ensemblfungi:YJR060W psi-mi:cbf3b_yeast(display_long)|uniprotkb:CEP3(gene name)|psi-mi:CEP3(display_short)|uniprotkb:CBF3(gene name synonym)|uniprotkb:YMR168C(locus name)|uniprotkb:YM8520.17C(orf name)|uniprotkb:CBF3B(gene name synonym)|uniprotkb:CSL1(gene name synonym) psi-mi:cbf1_yeast(display_long)|uniprotkb:CEP1(gene name synonym)|uniprotkb:CP1(gene name synonym)|uniprotkb:CPF1(gene name synonym)|uniprotkb:J1730(orf name)|uniprotkb:YJR060W(locus name)|uniprotkb:CBF1(gene name)|psi-mi:CBF1(display_short)|uniprotkb:Centromere-binding factor 1(gene name synonym)|uniprotkb:Centromere promoter factor 1(gene name synonym) psi-mi:"MI:0096"(pull down) Hemmerich et al. (2000) pubmed:11070082|mint:MINT-5213167 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7436183|mint:MINT-17037 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013891.1|sgd:S000004778|dip:DIP-5956N|ensemblfungi:YMR168C(gene)|ensemblfungi:YMR168C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000921"(septin ring assembly)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0031518"(CBF3 complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR031760|interpro:IPR036864|rcsb pdb:2QUQ|rcsb pdb:2VEQ|rcsb pdb:6F07|rcsb pdb:6FE8|rcsb pdb:6GSA|rcsb pdb:6GYS|rcsb pdb:7K79|rcsb pdb:7K7G|mint:MINT-433558(identity) refseq:NP_012594.1|sgd:S000003821|dip:DIP-2239N|mint:P17106|ensemblfungi:YJR060W(gene)|ensemblfungi:YJR060W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0089713"(Cbf1-Met4-Met28 complex)|go:"GO:0098781"(ncRNA transcription)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:MINT-433555(identity) - crc64:2E24A0508080A09B|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2001/06/23 2014/10/16 rogid:fX2WF64mv3m8KsmULd7CJVp9cOo559292 rogid:SjrIzQ9f1rrxeycid/060/5MRY8559292 intact-crc:AE0CE605F97FB5E2|rigid:jfXcqJSo2dw1CywcPqqSGmxRnD0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17106 uniprotkb:P32504 intact:EBI-4096|uniprotkb:Q6Q5N1|uniprotkb:P17623|uniprotkb:D6VWN1|ensemblfungi:YJR060W intact:EBI-4069|uniprotkb:E9P954|uniprotkb:D6VUS0|ensemblfungi:YGR140W psi-mi:cbf1_yeast(display_long)|uniprotkb:CEP1(gene name synonym)|uniprotkb:CP1(gene name synonym)|uniprotkb:CPF1(gene name synonym)|uniprotkb:J1730(orf name)|uniprotkb:YJR060W(locus name)|uniprotkb:CBF1(gene name)|psi-mi:CBF1(display_short)|uniprotkb:Centromere-binding factor 1(gene name synonym)|uniprotkb:Centromere promoter factor 1(gene name synonym) psi-mi:cbf3a_yeast(display_long)|uniprotkb:CEP2(gene name synonym)|uniprotkb:CTF14(gene name synonym)|uniprotkb:YGR140W(locus name)|uniprotkb:CBF2(gene name)|psi-mi:CBF2(display_short)|uniprotkb:CBF3A(gene name synonym)|uniprotkb:NDC10(gene name synonym)|uniprotkb:Chromosome transmission fidelity protein 14(gene name synonym)|uniprotkb:Kinetochore protein CTF14(gene name synonym)|uniprotkb:Centromere-binding factor 2(gene name synonym) psi-mi:"MI:0096"(pull down) Hemmerich et al. (2000) pubmed:11070082|mint:MINT-5213167 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7436192|mint:MINT-14094 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012594.1|sgd:S000003821|dip:DIP-2239N|mint:P17106|ensemblfungi:YJR060W(gene)|ensemblfungi:YJR060W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0089713"(Cbf1-Met4-Met28 complex)|go:"GO:0098781"(ncRNA transcription)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:MINT-433563(identity) sgd:S000003372|refseq:NP_011656.3|dip:DIP-5955N|mint:P32504|ensemblfungi:YGR140W(gene)|ensemblfungi:YGR140W_mRNA(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000921"(septin ring assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005819"(spindle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0031518"(CBF3 complex)|go:"GO:0051233"(spindle midzone)|interpro:IPR010998(Integrase, Lamba-type, N-terminal)|interpro:IPR022210|interpro:IPR031872|interpro:IPR038279|rcsb pdb:4ACO|rcsb pdb:6GSA|rcsb pdb:6GYP|rcsb pdb:6GYS|rcsb pdb:6GYU|mint:MINT-433566(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2001/06/23 2014/10/16 rogid:SjrIzQ9f1rrxeycid/060/5MRY8559292 rogid:QRPR20lvwdPWMKrzv5alh7uKljk559292 intact-crc:F347A79A25EDCF50|rigid:ZYiZQJry17YlsuLLzO/xFcgqL2k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35203 uniprotkb:P17106 intact:EBI-4085|uniprotkb:D6VZR7|ensemblfungi:YMR094W intact:EBI-4096|uniprotkb:Q6Q5N1|uniprotkb:P17623|uniprotkb:D6VWN1|ensemblfungi:YJR060W psi-mi:cbf3c_yeast(display_long)|uniprotkb:CTF13(gene name)|psi-mi:CTF13(display_short)|uniprotkb:CBF3C(gene name synonym)|uniprotkb:YMR094W(locus name)|uniprotkb:YM9582.19(orf name)|uniprotkb:YM6543.01(orf name)|uniprotkb:Chromosome transmission fidelity protein 13(gene name synonym)|uniprotkb:Kinetochore protein CTF13(gene name synonym) psi-mi:cbf1_yeast(display_long)|uniprotkb:CEP1(gene name synonym)|uniprotkb:CP1(gene name synonym)|uniprotkb:CPF1(gene name synonym)|uniprotkb:J1730(orf name)|uniprotkb:YJR060W(locus name)|uniprotkb:CBF1(gene name)|psi-mi:CBF1(display_short)|uniprotkb:Centromere-binding factor 1(gene name synonym)|uniprotkb:Centromere promoter factor 1(gene name synonym) psi-mi:"MI:0096"(pull down) Hemmerich et al. (2000) pubmed:11070082|mint:MINT-5213167 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7436201|mint:MINT-16196 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013812.1|sgd:S000004700|dip:DIP-1277N|ensemblfungi:YMR094W(gene)|ensemblfungi:YMR094W_mRNA(transcript)|go:"GO:0000921"(septin ring assembly)|go:"GO:0005634"(nucleus)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0031518"(CBF3 complex)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR032675|rcsb pdb:6FE8|rcsb pdb:6GSA|rcsb pdb:6GYP|rcsb pdb:6GYS|rcsb pdb:6GYU|rcsb pdb:7K79|mint:MINT-433574(identity) refseq:NP_012594.1|sgd:S000003821|dip:DIP-2239N|mint:P17106|ensemblfungi:YJR060W(gene)|ensemblfungi:YJR060W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0089713"(Cbf1-Met4-Met28 complex)|go:"GO:0098781"(ncRNA transcription)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:MINT-433571(identity) - crc64:77B1C012FD74E56F|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2001/06/23 2014/10/16 rogid:7aPRGLmtozW0jfSaqAThUR8/4XQ559292 rogid:SjrIzQ9f1rrxeycid/060/5MRY8559292 intact-crc:613C682CB4A65F90|rigid:2r95lrw/anfX2ALmDcwMrI8XbWE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)