#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O88811	uniprotkb:Q80U87	intact:EBI-2119154|uniprotkb:Q8C8Y4|uniprotkb:A2AU00|ensembl:ENSMUSP00000099820	intact:EBI-1765959|uniprotkb:Q80YP2|uniprotkb:Q8R0D3|uniprotkb:Q9EQU1|uniprotkb:Q9WVP5|uniprotkb:A2AI53|ensembl:ENSMUSP00000028841	psi-mi:stam2_mouse(display_long)|uniprotkb:Stam2(gene name)|psi-mi:Stam2(display_short)|uniprotkb:Hbp(gene name synonym)|uniprotkb:Hrs-binding protein(gene name synonym)	psi-mi:ubp8_mouse(display_long)|uniprotkb:Usp8(gene name)|psi-mi:Usp8(display_short)|uniprotkb:Kiaa0055(gene name synonym)|uniprotkb:Ubpy(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 8(gene name synonym)|uniprotkb:Deubiquitinating enzyme 8(gene name synonym)|uniprotkb:Ubiquitin isopeptidase Y(gene name synonym)|uniprotkb:Ubiquitin thioesterase 8(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Kato et al. (2000)	pubmed:10982817|mint:MINT-5212988	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7389592|mint:MINT-14003	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062641.1|ensembl:ENSMUSG00000055371(gene)|ensembl:ENSMUST00000102759(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR035675|interpro:IPR036028|rcsb pdb:1UJ0|reactome:R-MMU-182971|reactome:R-MMU-5689880|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-9013420|reactome:R-MMU-917729|mint:MINT-430780(identity)	refseq:NP_062703.2|ensembl:ENSMUST00000028841(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007032"(endosome organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030496"(midbody)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043197"(dendritic spine)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR015063(Region of unknown function DUF1873)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|mint:Q80U87|rcsb pdb:1UJ0|reactome:R-MMU-1358803|reactome:R-MMU-4641263|reactome:R-MMU-5689880|reactome:R-MMU-6807004|ensembl:ENSMUSG00000027363(gene)|mint:MINT-430774(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:domino|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/02/14	2014/10/16	rogid:ruTJW3K1aXdRx2pccUmFMxPy6+E10090	rogid:PhHue+cov/Z/PGJqR8RtRQF6qco10090	intact-crc:F144D3F4E6641CBE|rigid:F78EpBuPYvNy59sBlHnFwQYHXnk	false	binding-associated region:205-260(MINT-430781)	binding-associated region:405-414(MINT-430775)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O88811	uniprotkb:O95630	intact:EBI-2119154|uniprotkb:Q8C8Y4|uniprotkb:A2AU00|ensembl:ENSMUSP00000099820	intact:EBI-396676|uniprotkb:Q3MJE7|uniprotkb:D6W5H7|uniprotkb:B5M0B6|ensembl:ENSP00000344742|ensembl:ENSP00000377633|ensembl:ENSP00000377636|ensembl:ENSP00000386548|ensembl:ENSP00000506833|ensembl:ENSP00000506845|ensembl:ENSP00000506865|ensembl:ENSP00000506958|ensembl:ENSP00000507014|ensembl:ENSP00000507054|ensembl:ENSP00000507081|ensembl:ENSP00000507092|ensembl:ENSP00000507639|ensembl:ENSP00000507658|ensembl:ENSP00000507864	psi-mi:stam2_mouse(display_long)|uniprotkb:Stam2(gene name)|psi-mi:Stam2(display_short)|uniprotkb:Hbp(gene name synonym)|uniprotkb:Hrs-binding protein(gene name synonym)	psi-mi:stabp_human(display_long)|uniprotkb:AMSH(gene name synonym)|uniprotkb:STAMBP(gene name)|psi-mi:STAMBP(display_short)|uniprotkb:Associated molecule with the SH3 domain of STAM(gene name synonym)|uniprotkb:Endosome-associated ubiquitin isopeptidase(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Kato et al. (2000)	pubmed:10982817|mint:MINT-5212988	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7389632|mint:MINT-18773	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062641.1|ensembl:ENSMUSG00000055371(gene)|ensembl:ENSMUST00000102759(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR035675|interpro:IPR036028|rcsb pdb:1UJ0|reactome:R-MMU-182971|reactome:R-MMU-5689880|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-9013420|reactome:R-MMU-917729|mint:MINT-430826(identity)	refseq:NP_006454.1|refseq:NP_964010.1|refseq:NP_998787.1|refseq:XP_005264145.1|refseq:XP_011530785.1|refseq:XP_016858664.1|go:"GO:0016020"(membrane)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR015063(Region of unknown function DUF1873)|interpro:IPR037518|interpro:IPR044098|mint:O95630|rcsb pdb:2XZE|rcsb pdb:3RZU|rcsb pdb:3RZV|rcsb pdb:5IXF|reactome:R-HSA-5689901|ensembl:ENSG00000124356(gene)|ensembl:ENST00000339566(transcript)|ensembl:ENST00000394070(transcript)|ensembl:ENST00000394073(transcript)|ensembl:ENST00000409707(transcript)|ensembl:ENST00000682351(transcript)|ensembl:ENST00000682379(transcript)|ensembl:ENST00000682558(transcript)|ensembl:ENST00000682847(transcript)|ensembl:ENST00000683036(transcript)|ensembl:ENST00000683317(transcript)|ensembl:ENST00000683518(transcript)|ensembl:ENST00000683818(transcript)|ensembl:ENST00000684095(transcript)|ensembl:ENST00000684312(transcript)|ensembl:ENST00000684585(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|dip:DIP-33062N|mint:MINT-430820(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:domino|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/02/14	2014/10/16	rogid:ruTJW3K1aXdRx2pccUmFMxPy6+E10090	rogid:JUvszgPz9rog/OEpmABJ295BaLw9606	intact-crc:4AED5CE86018E4C3|rigid:DAhNesTUIxJljlu31yVDYd18NXo	false	binding-associated region:205-260(MINT-430827)	binding-associated region:231-239(MINT-430821)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O88811	uniprotkb:Q80U87	intact:EBI-2119154|uniprotkb:Q8C8Y4|uniprotkb:A2AU00|ensembl:ENSMUSP00000099820	intact:EBI-1765959|uniprotkb:Q80YP2|uniprotkb:Q8R0D3|uniprotkb:Q9EQU1|uniprotkb:Q9WVP5|uniprotkb:A2AI53|ensembl:ENSMUSP00000028841	psi-mi:stam2_mouse(display_long)|uniprotkb:Stam2(gene name)|psi-mi:Stam2(display_short)|uniprotkb:Hbp(gene name synonym)|uniprotkb:Hrs-binding protein(gene name synonym)	psi-mi:ubp8_mouse(display_long)|uniprotkb:Usp8(gene name)|psi-mi:Usp8(display_short)|uniprotkb:Kiaa0055(gene name synonym)|uniprotkb:Ubpy(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 8(gene name synonym)|uniprotkb:Deubiquitinating enzyme 8(gene name synonym)|uniprotkb:Ubiquitin isopeptidase Y(gene name synonym)|uniprotkb:Ubiquitin thioesterase 8(gene name synonym)	psi-mi:"MI:0049"(filter binding)	Kato et al. (2000)	pubmed:10982817|mint:MINT-5212988	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7389695|mint:MINT-14004	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062641.1|ensembl:ENSMUSG00000055371(gene)|ensembl:ENSMUST00000102759(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR035675|interpro:IPR036028|rcsb pdb:1UJ0|reactome:R-MMU-182971|reactome:R-MMU-5689880|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-9013420|reactome:R-MMU-917729|mint:MINT-430796(identity)	refseq:NP_062703.2|ensembl:ENSMUST00000028841(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007032"(endosome organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030496"(midbody)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043197"(dendritic spine)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR015063(Region of unknown function DUF1873)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|mint:Q80U87|rcsb pdb:1UJ0|reactome:R-MMU-1358803|reactome:R-MMU-4641263|reactome:R-MMU-5689880|reactome:R-MMU-6807004|ensembl:ENSMUSG00000027363(gene)|mint:MINT-430790(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:domino|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2001/02/14	2014/10/16	rogid:ruTJW3K1aXdRx2pccUmFMxPy6+E10090	rogid:PhHue+cov/Z/PGJqR8RtRQF6qco10090	intact-crc:30CA19CDE5EE2875|rigid:F78EpBuPYvNy59sBlHnFwQYHXnk	false	binding-associated region:205-260(MINT-430797)	binding-associated region:405-414(MINT-430791)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P70297	uniprotkb:O95630	intact:EBI-7389748|intact:MINT-96905|ensembl:ENSMUSP00000100025	intact:EBI-396676|uniprotkb:Q3MJE7|uniprotkb:D6W5H7|uniprotkb:B5M0B6|ensembl:ENSP00000344742|ensembl:ENSP00000377633|ensembl:ENSP00000377636|ensembl:ENSP00000386548|ensembl:ENSP00000506833|ensembl:ENSP00000506845|ensembl:ENSP00000506865|ensembl:ENSP00000506958|ensembl:ENSP00000507014|ensembl:ENSP00000507054|ensembl:ENSP00000507081|ensembl:ENSP00000507092|ensembl:ENSP00000507639|ensembl:ENSP00000507658|ensembl:ENSP00000507864	psi-mi:stam1_mouse(display_long)|uniprotkb:Stam(gene name)|psi-mi:Stam(display_short)|uniprotkb:Stam1(gene name synonym)	psi-mi:stabp_human(display_long)|uniprotkb:AMSH(gene name synonym)|uniprotkb:STAMBP(gene name)|psi-mi:STAMBP(display_short)|uniprotkb:Associated molecule with the SH3 domain of STAM(gene name synonym)|uniprotkb:Endosome-associated ubiquitin isopeptidase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kato et al. (2000)	pubmed:10982817|mint:MINT-5212988	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7389743|mint:MINT-17734	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035614.1|ensembl:ENSMUSG00000026718(gene)|ensembl:ENSMUST00000102960(transcript)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR035657|interpro:IPR036028|mint:P70297|reactome:R-MMU-182971|reactome:R-MMU-5689901|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-9013420|reactome:R-MMU-917729|mint:MINT-430841(identity)	refseq:NP_006454.1|refseq:NP_964010.1|refseq:NP_998787.1|refseq:XP_005264145.1|refseq:XP_011530785.1|refseq:XP_016858664.1|go:"GO:0016020"(membrane)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR015063(Region of unknown function DUF1873)|interpro:IPR037518|interpro:IPR044098|mint:O95630|rcsb pdb:2XZE|rcsb pdb:3RZU|rcsb pdb:3RZV|rcsb pdb:5IXF|reactome:R-HSA-5689901|ensembl:ENSG00000124356(gene)|ensembl:ENST00000339566(transcript)|ensembl:ENST00000394070(transcript)|ensembl:ENST00000394073(transcript)|ensembl:ENST00000409707(transcript)|ensembl:ENST00000682351(transcript)|ensembl:ENST00000682379(transcript)|ensembl:ENST00000682558(transcript)|ensembl:ENST00000682847(transcript)|ensembl:ENST00000683036(transcript)|ensembl:ENST00000683317(transcript)|ensembl:ENST00000683518(transcript)|ensembl:ENST00000683818(transcript)|ensembl:ENST00000684095(transcript)|ensembl:ENST00000684312(transcript)|ensembl:ENST00000684585(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|dip:DIP-33062N|mint:MINT-430835(identity)	-	comment:mint|function:Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and c-myc induction. May also play a role in endocytic trafficking as well as in T-cell development|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:domino|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2001/02/14	2014/10/16	rogid:PPoDLENlcg2H6/QBtyxf5au2Vow10090	rogid:JUvszgPz9rog/OEpmABJ295BaLw9606	intact-crc:24571E39977DC809|rigid:9r5M7I4hxX/UJ1LZwoFtl0Ui/0k	false	binding-associated region:213-268(MINT-430842)	binding-associated region:231-239(MINT-430836)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q80U87	uniprotkb:Q60631	intact:EBI-1765959|uniprotkb:Q80YP2|uniprotkb:Q8R0D3|uniprotkb:Q9EQU1|uniprotkb:Q9WVP5|uniprotkb:A2AI53|ensembl:ENSMUSP00000028841	intact:EBI-1688|uniprotkb:Q61240|ensembl:ENSMUSP00000021090|ensembl:ENSMUSP00000102106	psi-mi:ubp8_mouse(display_long)|uniprotkb:Usp8(gene name)|psi-mi:Usp8(display_short)|uniprotkb:Kiaa0055(gene name synonym)|uniprotkb:Ubpy(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 8(gene name synonym)|uniprotkb:Deubiquitinating enzyme 8(gene name synonym)|uniprotkb:Ubiquitin isopeptidase Y(gene name synonym)|uniprotkb:Ubiquitin thioesterase 8(gene name synonym)	psi-mi:grb2_mouse(display_long)|uniprotkb:Grb2(gene name)|psi-mi:Grb2(display_short)|uniprotkb:Adapter protein GRB2(gene name synonym)|uniprotkb:SH2/SH3 adapter GRB2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kato et al. (2000)	pubmed:10982817|mint:MINT-5212988	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7389803|mint:MINT-18606	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062703.2|ensembl:ENSMUST00000028841(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007032"(endosome organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030496"(midbody)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043197"(dendritic spine)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR015063(Region of unknown function DUF1873)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|mint:Q80U87|rcsb pdb:1UJ0|reactome:R-MMU-1358803|reactome:R-MMU-4641263|reactome:R-MMU-5689880|reactome:R-MMU-6807004|ensembl:ENSMUSG00000027363(gene)|mint:MINT-430806(identity)	refseq:NP_032189.1|refseq:NP_001300865.1|refseq:NP_001300866.1|dip:DIP-259N|ensembl:ENSMUSG00000059923(gene)|ensembl:ENSMUST00000021090(transcript)|ensembl:ENSMUST00000106497(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007568"(aging)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031623"(receptor internalization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0070436"(Grb2-EGFR complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035641|interpro:IPR035643|interpro:IPR036028|interpro:IPR036860|mint:Q60631|rcsb pdb:1GBQ|rcsb pdb:1GBR|rcsb pdb:2GBQ|rcsb pdb:3GBQ|rcsb pdb:4GBQ|reactome:R-MMU-109704|reactome:R-MMU-112412|reactome:R-MMU-1250347|reactome:R-MMU-1257604|reactome:R-MMU-1295596|reactome:R-MMU-1433557|reactome:R-MMU-1433559|reactome:R-MMU-167044|reactome:R-MMU-179812|reactome:R-MMU-180292|reactome:R-MMU-180336|reactome:R-MMU-182971|reactome:R-MMU-186763|reactome:R-MMU-1963640|reactome:R-MMU-1963642|reactome:R-MMU-2029482|reactome:R-MMU-210993|reactome:R-MMU-2179392|reactome:R-MMU-2424491|reactome:R-MMU-2428933|reactome:R-MMU-2730905|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-354194|reactome:R-MMU-375165|reactome:R-MMU-388841|reactome:R-MMU-389359|reactome:R-MMU-391160|reactome:R-MMU-5654688|reactome:R-MMU-5654689|reactome:R-MMU-5654693|reactome:R-MMU-5654695|reactome:R-MMU-5654699|reactome:R-MMU-5654700|reactome:R-MMU-5654704|reactome:R-MMU-5654706|reactome:R-MMU-5654710|reactome:R-MMU-5654712|reactome:R-MMU-5654719|reactome:R-MMU-5654720|reactome:R-MMU-5654726|reactome:R-MMU-5654727|reactome:R-MMU-5654732|reactome:R-MMU-5654733|reactome:R-MMU-5663213|reactome:R-MMU-5673001|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-74749|reactome:R-MMU-74751|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8853659|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8865999|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8983432|reactome:R-MMU-9027284|reactome:R-MMU-9028731|reactome:R-MMU-912526|reactome:R-MMU-912631|reactome:R-MMU-9607240|reactome:R-MMU-9674555|reactome:R-MMU-983695|mint:MINT-430812(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:domino|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2001/02/14	2014/10/16	rogid:PhHue+cov/Z/PGJqR8RtRQF6qco10090	rogid:0Zuj4toqaPeuo3snXLa7fckMXU410090	intact-crc:F2605BDA462A5258|rigid:pVlifps6I18kHUlSiFhem+FzR7k	false	binding-associated region:405-413(MINT-430807)	binding-associated region:?-?(MINT-430813)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)