#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9NQS1	uniprotkb:O14727	intact:EBI-7370203|intact:MINT-143075|ensembl:ENSP00000306822	intact:EBI-446492|uniprotkb:B2RMX8|uniprotkb:O43297|uniprotkb:Q7Z438|uniprotkb:Q9BXZ6|uniprotkb:Q9UBZ5|uniprotkb:Q9UGN8|uniprotkb:Q9UGN9|uniprotkb:Q9UGP0|uniprotkb:Q9UJ58|uniprotkb:Q9UJ59|uniprotkb:Q9UJ60|uniprotkb:Q9UJ61|uniprotkb:Q9UJ62|uniprotkb:Q9UJ63|uniprotkb:Q9UJ64|uniprotkb:Q9UJ65|uniprotkb:Q9UJ66|uniprotkb:Q9UJ67|uniprotkb:Q9UNC9|ensembl:ENSP00000448165	psi-mi:aven_human(display_long)|uniprotkb:AVEN(gene name)|psi-mi:AVEN(display_short)	psi-mi:apaf_human(display_long)|uniprotkb:APAF1(gene name)|psi-mi:APAF1(display_short)|uniprotkb:KIAA0413(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Chau et al. (2000)	pubmed:10949025|mint:MINT-5212921	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7370219|mint:MINT-17186	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065104.1|ensembl:ENSG00000169857(gene)|ensembl:ENST00000306730(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|interpro:IPR026187|reactome:R-HSA-111458|reactome:R-HSA-9627069|mint:MINT-429852(identity)	refseq:NP_001151.1|refseq:NP_037361.1|refseq:NP_863651.1|refseq:NP_863658.1|refseq:NP_863659.1|dip:DIP-27624N|interpro:IPR042197|go:"GO:0007568"(aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0008635"(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0030154"(cell differentiation)|mint:O14727|rcsb pdb:1C15|go:"GO:0031072"(heat shock protein binding)|rcsb pdb:1CWW|rcsb pdb:1CY5|rcsb pdb:1Z6T|go:"GO:0032991"(protein-containing complex)|go:"GO:0034774"(secretory granule lumen)|rcsb pdb:2P1H|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|rcsb pdb:2YGS|rcsb pdb:3J2T|go:"GO:0043065"(positive regulation of apoptotic process)|rcsb pdb:3JBT|rcsb pdb:3YGS|go:"GO:0043293"(apoptosome)|rcsb pdb:4RHW|rcsb pdb:5JUY|rcsb pdb:5WVC|go:"GO:0043531"(ADP binding)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:5WVE|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0072432"(response to G1 DNA damage checkpoint signaling)|reactome:R-HSA-111458|reactome:R-HSA-111459|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|reactome:R-HSA-111463|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001680(WD40 repeat)|interpro:IPR002182(NB-ARC)|reactome:R-HSA-111464|interpro:IPR011029(DEATH-like)|interpro:IPR015943(WD40/YVTN repeat-like)|reactome:R-HSA-6798695|interpro:IPR017251(Apoptotic protease-activating factor 1)|interpro:IPR019775|reactome:R-HSA-6803207|interpro:IPR020472|reactome:R-HSA-8953750|interpro:IPR027417|reactome:R-HSA-9627069|interpro:IPR036322|interpro:IPR036388|interpro:IPR037963|interpro:IPR041452|ensembl:ENSG00000120868(gene)|ensembl:ENST00000551964(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001822"(kidney development)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|mint:MINT-429849(identity)	-	comment:mint|function:Protects against apoptosis mediated by Apaf-1|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/08/31	2014/10/16	rogid:BWW3ojRrcqMDdORrb5pxfj7RAwU9606	rogid:/jz44wizyUPTNZLQtgjh7YLt/mE9606	intact-crc:34743657AF411DF2|rigid:dKHuwgV3N/92/2QR9AHDiR563V0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NQS1	uniprotkb:O14727	intact:EBI-7370203|intact:MINT-143075|ensembl:ENSP00000306822	intact:EBI-446492|uniprotkb:B2RMX8|uniprotkb:O43297|uniprotkb:Q7Z438|uniprotkb:Q9BXZ6|uniprotkb:Q9UBZ5|uniprotkb:Q9UGN8|uniprotkb:Q9UGN9|uniprotkb:Q9UGP0|uniprotkb:Q9UJ58|uniprotkb:Q9UJ59|uniprotkb:Q9UJ60|uniprotkb:Q9UJ61|uniprotkb:Q9UJ62|uniprotkb:Q9UJ63|uniprotkb:Q9UJ64|uniprotkb:Q9UJ65|uniprotkb:Q9UJ66|uniprotkb:Q9UJ67|uniprotkb:Q9UNC9|ensembl:ENSP00000448165	psi-mi:aven_human(display_long)|uniprotkb:AVEN(gene name)|psi-mi:AVEN(display_short)	psi-mi:apaf_human(display_long)|uniprotkb:APAF1(gene name)|psi-mi:APAF1(display_short)|uniprotkb:KIAA0413(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Chau et al. (2000)	pubmed:10949025|mint:MINT-5212921	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7370229|mint:MINT-17187	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065104.1|ensembl:ENSG00000169857(gene)|ensembl:ENST00000306730(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|interpro:IPR026187|reactome:R-HSA-111458|reactome:R-HSA-9627069|mint:MINT-429860(identity)	refseq:NP_001151.1|refseq:NP_037361.1|refseq:NP_863651.1|refseq:NP_863658.1|refseq:NP_863659.1|dip:DIP-27624N|interpro:IPR042197|go:"GO:0007568"(aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0008635"(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0030154"(cell differentiation)|mint:O14727|rcsb pdb:1C15|go:"GO:0031072"(heat shock protein binding)|rcsb pdb:1CWW|rcsb pdb:1CY5|rcsb pdb:1Z6T|go:"GO:0032991"(protein-containing complex)|go:"GO:0034774"(secretory granule lumen)|rcsb pdb:2P1H|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|rcsb pdb:2YGS|rcsb pdb:3J2T|go:"GO:0043065"(positive regulation of apoptotic process)|rcsb pdb:3JBT|rcsb pdb:3YGS|go:"GO:0043293"(apoptosome)|rcsb pdb:4RHW|rcsb pdb:5JUY|rcsb pdb:5WVC|go:"GO:0043531"(ADP binding)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:5WVE|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0072432"(response to G1 DNA damage checkpoint signaling)|reactome:R-HSA-111458|reactome:R-HSA-111459|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|reactome:R-HSA-111463|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001680(WD40 repeat)|interpro:IPR002182(NB-ARC)|reactome:R-HSA-111464|interpro:IPR011029(DEATH-like)|interpro:IPR015943(WD40/YVTN repeat-like)|reactome:R-HSA-6798695|interpro:IPR017251(Apoptotic protease-activating factor 1)|interpro:IPR019775|reactome:R-HSA-6803207|interpro:IPR020472|reactome:R-HSA-8953750|interpro:IPR027417|reactome:R-HSA-9627069|interpro:IPR036322|interpro:IPR036388|interpro:IPR037963|interpro:IPR041452|ensembl:ENSG00000120868(gene)|ensembl:ENST00000551964(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001822"(kidney development)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|mint:MINT-429857(identity)	-	comment:mint|function:Protects against apoptosis mediated by Apaf-1|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/08/31	2014/10/16	rogid:BWW3ojRrcqMDdORrb5pxfj7RAwU9606	rogid:/jz44wizyUPTNZLQtgjh7YLt/mE9606	intact-crc:2AA9FA3231C974BF|rigid:dKHuwgV3N/92/2QR9AHDiR563V0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)