#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P32383	uniprotkb:P40969	intact:EBI-13485|uniprotkb:D6W3A2|ensemblfungi:YPL268W	intact:EBI-4077|uniprotkb:D6VZZ0|ensemblfungi:YMR168C	psi-mi:plc1_yeast(display_long)|uniprotkb:PLC1(gene name)|psi-mi:PLC1(display_short)|uniprotkb:Phosphoinositide phospholipase C(gene name synonym)|uniprotkb:Phospholipase C-1(gene name synonym)|uniprotkb:YPL268W(locus name)	psi-mi:cbf3b_yeast(display_long)|uniprotkb:CEP3(gene name)|psi-mi:CEP3(display_short)|uniprotkb:CBF3(gene name synonym)|uniprotkb:YMR168C(locus name)|uniprotkb:YM8520.17C(orf name)|uniprotkb:CBF3B(gene name synonym)|uniprotkb:CSL1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Lin et al. (2000)	pubmed:10779349|mint:MINT-5212515|doi:10.1128/MCB.20.10.3597-3607.2000	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7268722|mint:MINT-17358	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015055.1|sgd:S000006189|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR017946|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|ensemblfungi:YPL268W(gene)|ensemblfungi:YPL268W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0009395"(phospholipid catabolic process)|go:"GO:0032958"(inositol phosphate biosynthetic process)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|reactome:R-SCE-112043|reactome:R-SCE-1855204|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-434316|interpro:IPR015359(Phospholipase C, phosphoinositol-specific, EF-hand-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR037755|mint:P32383|interpro:IPR035892|mint:MINT-416766(identity)	refseq:NP_013891.1|sgd:S000004778|dip:DIP-5956N|ensemblfungi:YMR168C(gene)|ensemblfungi:YMR168C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000921"(septin ring assembly)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0031518"(CBF3 complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR031760|interpro:IPR036864|rcsb pdb:2QUQ|rcsb pdb:2VEQ|rcsb pdb:6F07|rcsb pdb:6FE8|rcsb pdb:6GSA|rcsb pdb:6GYS|rcsb pdb:7K79|rcsb pdb:7K7G|mint:MINT-416760(identity)	-	comment:"Stoichiometry: 1.0"	crc64:2E24A0508080A09B|comment:"Stoichiometry: 1.0"	comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/06/23	2014/10/16	rogid:E3fBblnaa1w/+ezJKNhAKN1dabg559292	rogid:fX2WF64mv3m8KsmULd7CJVp9cOo559292	intact-crc:5C9FE5E109B5B2AD|rigid:5Kk92npXC/qwkykvWLxA4L/E7Lk	false	tag:?-?(MINT-416767)	tag:?-?(MINT-416761)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32504	uniprotkb:P32383	intact:EBI-4069|uniprotkb:E9P954|uniprotkb:D6VUS0|ensemblfungi:YGR140W	intact:EBI-13485|uniprotkb:D6W3A2|ensemblfungi:YPL268W	psi-mi:cbf3a_yeast(display_long)|uniprotkb:CEP2(gene name synonym)|uniprotkb:CTF14(gene name synonym)|uniprotkb:YGR140W(locus name)|uniprotkb:CBF2(gene name)|psi-mi:CBF2(display_short)|uniprotkb:CBF3A(gene name synonym)|uniprotkb:NDC10(gene name synonym)|uniprotkb:Chromosome transmission fidelity protein 14(gene name synonym)|uniprotkb:Kinetochore protein CTF14(gene name synonym)|uniprotkb:Centromere-binding factor 2(gene name synonym)	psi-mi:plc1_yeast(display_long)|uniprotkb:PLC1(gene name)|psi-mi:PLC1(display_short)|uniprotkb:Phosphoinositide phospholipase C(gene name synonym)|uniprotkb:Phospholipase C-1(gene name synonym)|uniprotkb:YPL268W(locus name)	psi-mi:"MI:0018"(two hybrid)	Lin et al. (2000)	pubmed:10779349|mint:MINT-5212515|doi:10.1128/MCB.20.10.3597-3607.2000	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7268737|mint:MINT-14425	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003372|refseq:NP_011656.3|dip:DIP-5955N|mint:P32504|ensemblfungi:YGR140W(gene)|ensemblfungi:YGR140W_mRNA(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000921"(septin ring assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005819"(spindle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0031518"(CBF3 complex)|go:"GO:0051233"(spindle midzone)|interpro:IPR010998(Integrase, Lamba-type, N-terminal)|interpro:IPR022210|interpro:IPR031872|interpro:IPR038279|rcsb pdb:4ACO|rcsb pdb:6GSA|rcsb pdb:6GYP|rcsb pdb:6GYS|rcsb pdb:6GYU|mint:MINT-416810(identity)	refseq:NP_015055.1|sgd:S000006189|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR017946|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|ensemblfungi:YPL268W(gene)|ensemblfungi:YPL268W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0009395"(phospholipid catabolic process)|go:"GO:0032958"(inositol phosphate biosynthetic process)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|reactome:R-SCE-112043|reactome:R-SCE-1855204|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-434316|interpro:IPR015359(Phospholipase C, phosphoinositol-specific, EF-hand-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR037755|mint:P32383|interpro:IPR035892|mint:MINT-416804(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/06/23	2014/10/16	rogid:QRPR20lvwdPWMKrzv5alh7uKljk559292	rogid:E3fBblnaa1w/+ezJKNhAKN1dabg559292	intact-crc:40C5E3503357CBEE|rigid:4/67jBnD8RJIMKkdlEtwyQ2s5dE	false	tag:?-?(MINT-416811)	tag:?-?(MINT-416805)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32504	uniprotkb:P32383	intact:EBI-4069|uniprotkb:E9P954|uniprotkb:D6VUS0|ensemblfungi:YGR140W	intact:EBI-13485|uniprotkb:D6W3A2|ensemblfungi:YPL268W	psi-mi:cbf3a_yeast(display_long)|uniprotkb:CEP2(gene name synonym)|uniprotkb:CTF14(gene name synonym)|uniprotkb:YGR140W(locus name)|uniprotkb:CBF2(gene name)|psi-mi:CBF2(display_short)|uniprotkb:CBF3A(gene name synonym)|uniprotkb:NDC10(gene name synonym)|uniprotkb:Chromosome transmission fidelity protein 14(gene name synonym)|uniprotkb:Kinetochore protein CTF14(gene name synonym)|uniprotkb:Centromere-binding factor 2(gene name synonym)	psi-mi:plc1_yeast(display_long)|uniprotkb:PLC1(gene name)|psi-mi:PLC1(display_short)|uniprotkb:Phosphoinositide phospholipase C(gene name synonym)|uniprotkb:Phospholipase C-1(gene name synonym)|uniprotkb:YPL268W(locus name)	psi-mi:"MI:0096"(pull down)	Lin et al. (2000)	pubmed:10779349|mint:MINT-5212515|doi:10.1128/MCB.20.10.3597-3607.2000	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7268759|mint:MINT-14426	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003372|refseq:NP_011656.3|dip:DIP-5955N|mint:P32504|ensemblfungi:YGR140W(gene)|ensemblfungi:YGR140W_mRNA(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000921"(septin ring assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005819"(spindle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0031518"(CBF3 complex)|go:"GO:0051233"(spindle midzone)|interpro:IPR010998(Integrase, Lamba-type, N-terminal)|interpro:IPR022210|interpro:IPR031872|interpro:IPR038279|rcsb pdb:4ACO|rcsb pdb:6GSA|rcsb pdb:6GYP|rcsb pdb:6GYS|rcsb pdb:6GYU|mint:MINT-416799(identity)	refseq:NP_015055.1|sgd:S000006189|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR017946|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|ensemblfungi:YPL268W(gene)|ensemblfungi:YPL268W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0009395"(phospholipid catabolic process)|go:"GO:0032958"(inositol phosphate biosynthetic process)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|reactome:R-SCE-112043|reactome:R-SCE-1855204|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-434316|interpro:IPR015359(Phospholipase C, phosphoinositol-specific, EF-hand-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR037755|mint:P32383|interpro:IPR035892|mint:MINT-416796(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2001/06/23	2014/10/16	rogid:QRPR20lvwdPWMKrzv5alh7uKljk559292	rogid:E3fBblnaa1w/+ezJKNhAKN1dabg559292	intact-crc:FF2D0B583A002F09|rigid:4/67jBnD8RJIMKkdlEtwyQ2s5dE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)