#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q60700	uniprotkb:Q60700	intact:EBI-7248355|uniprotkb:P70286|uniprotkb:Q8C4N7|intact:MINT-126821|uniprotkb:Q8CDL6|uniprotkb:Q3TLL7|uniprotkb:Q8CBX3|ensembl:ENSMUSP00000023812|ensembl:ENSMUSP00000127629|ensembl:ENSMUSP00000133209	intact:EBI-7248355|uniprotkb:P70286|uniprotkb:Q8C4N7|intact:MINT-126821|uniprotkb:Q8CDL6|uniprotkb:Q3TLL7|uniprotkb:Q8CBX3|ensembl:ENSMUSP00000023812|ensembl:ENSMUSP00000127629|ensembl:ENSMUSP00000133209	psi-mi:m3k12_mouse(display_long)|uniprotkb:Map3k12(gene name)|psi-mi:Map3k12(display_short)|uniprotkb:Zpk(gene name synonym)|uniprotkb:Mixed lineage kinase(gene name synonym)|uniprotkb:Leucine-zipper protein kinase(gene name synonym)|uniprotkb:Dual leucine zipper bearing kinase(gene name synonym)|uniprotkb:MAPK-upstream kinase(gene name synonym)	psi-mi:m3k12_mouse(display_long)|uniprotkb:Map3k12(gene name)|psi-mi:Map3k12(display_short)|uniprotkb:Zpk(gene name synonym)|uniprotkb:Mixed lineage kinase(gene name synonym)|uniprotkb:Leucine-zipper protein kinase(gene name synonym)|uniprotkb:Dual leucine zipper bearing kinase(gene name synonym)|uniprotkb:MAPK-upstream kinase(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Wang et al. (2000)	pubmed:10748113|mint:MINT-5212407	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7248351|mint:MINT-14427	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033608.3|refseq:NP_001157115.1|ensembl:ENSMUSG00000023050(gene)|ensembl:ENSMUST00000023812(transcript)|ensembl:ENSMUST00000169377(transcript)|ensembl:ENSMUST00000171565(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004706"(JUN kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:2000672"(negative regulation of motor neuron apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017419(Mitogen-activated protein kinase kinase kinase, 12/13)|interpro:IPR027257|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:XP_017172113.1|refseq:XP_017172114.1|mint:MINT-414756(identity)	refseq:NP_033608.3|refseq:NP_001157115.1|ensembl:ENSMUSG00000023050(gene)|ensembl:ENSMUST00000023812(transcript)|ensembl:ENSMUST00000169377(transcript)|ensembl:ENSMUST00000171565(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004706"(JUN kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:2000672"(negative regulation of motor neuron apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017419(Mitogen-activated protein kinase kinase kinase, 12/13)|interpro:IPR027257|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:XP_017172113.1|refseq:XP_017172114.1|mint:MINT-414751(identity)	-	comment:mint|function:May be an activator of the JNK/SAPK pathway. Phosphorylates beta-casein, histone 1 and myelin basic protein in vitro|comment:"Stoichiometry: 1.0"	comment:mint|function:May be an activator of the JNK/SAPK pathway. Phosphorylates beta-casein, histone 1 and myelin basic protein in vitro|comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/06/05	2014/10/16	rogid:fI+BJJCkAZxivJNAIAKTrbdIz/410090	rogid:fI+BJJCkAZxivJNAIAKTrbdIz/410090	intact-crc:C5D9B73DC5885F3D|rigid:7gnzJdTEdaB8uuMH8Fi8O9g38Xc	false	binding-associated region:405-520(MINT-414757)	binding-associated region:405-520(MINT-414752)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q60700	uniprotkb:Q9WVI9	intact:EBI-7248355|uniprotkb:P70286|uniprotkb:Q8C4N7|intact:MINT-126821|uniprotkb:Q8CDL6|uniprotkb:Q3TLL7|uniprotkb:Q8CBX3|ensembl:ENSMUSP00000023812|ensembl:ENSMUSP00000127629|ensembl:ENSMUSP00000133209	intact:EBI-74515|ensembl:ENSMUSP00000050773|uniprotkb:O35145|uniprotkb:Q925J8|uniprotkb:Q9R1H9|uniprotkb:Q9R1Z1|uniprotkb:Q9WVI7|uniprotkb:Q9WVI8	psi-mi:m3k12_mouse(display_long)|uniprotkb:Map3k12(gene name)|psi-mi:Map3k12(display_short)|uniprotkb:Zpk(gene name synonym)|uniprotkb:Mixed lineage kinase(gene name synonym)|uniprotkb:Leucine-zipper protein kinase(gene name synonym)|uniprotkb:Dual leucine zipper bearing kinase(gene name synonym)|uniprotkb:MAPK-upstream kinase(gene name synonym)	psi-mi:jip1_mouse(display_long)|uniprotkb:Mapk8ip1(gene name)|psi-mi:Mapk8ip1(display_short)|uniprotkb:Ib1(gene name synonym)|uniprotkb:Jip1(gene name synonym)|uniprotkb:Mapk8ip(gene name synonym)|uniprotkb:Prkm8ip(gene name synonym)|uniprotkb:Islet-brain-1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 1(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 1(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Wang et al. (2000)	pubmed:10748113|mint:MINT-5212407	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7248484|mint:MINT-16919	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033608.3|refseq:NP_001157115.1|ensembl:ENSMUSG00000023050(gene)|ensembl:ENSMUST00000023812(transcript)|ensembl:ENSMUST00000169377(transcript)|ensembl:ENSMUST00000171565(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004706"(JUN kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:2000672"(negative regulation of motor neuron apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017419(Mitogen-activated protein kinase kinase kinase, 12/13)|interpro:IPR027257|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:XP_017172113.1|refseq:XP_017172114.1|mint:MINT-414763(identity)	go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007165"(signal transduction)|go:"GO:0007258"(JUN phosphorylation)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0044302"(dentate gyrus mossy fiber)|go:"GO:0045202"(synapse)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:2000564"(regulation of CD8-positive, alpha-beta T cell proliferation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035638|interpro:IPR036028|rcsb pdb:1UKH|rcsb pdb:1UKI|rcsb pdb:3O17|rcsb pdb:3O2M|rcsb pdb:3V3V|rcsb pdb:6F5E|go:"GO:0005078"(MAP-kinase scaffold activity)|ensembl:ENSMUST00000050312(transcript)|ensembl:ENSMUSG00000027223(gene)|refseq:NP_035292.2|mint:MINT-414769(identity)	-	comment:mint|function:May be an activator of the JNK/SAPK pathway. Phosphorylates beta-casein, histone 1 and myelin basic protein in vitro|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/06/05	2014/10/16	rogid:fI+BJJCkAZxivJNAIAKTrbdIz/410090	rogid:r8Xy/vpp0kYLCZ7vw1sE666dk/g10090	intact-crc:67EBD2EF8DE2C3C4|rigid:L501eyXG4tLyULDXi1yppL+8C+U	false	binding-associated region:1-418(MINT-414764)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)