#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9UMZ2	uniprotkb:Q9UJY4	intact:EBI-7240490|uniprotkb:Q6ZT17|uniprotkb:B7ZKZ3|uniprotkb:Q17RI2|uniprotkb:Q5BKU5|intact:MINT-126209|uniprotkb:B7ZKZ2|intact:EBI-28973092|ensembl:ENSP00000480288|ensembl:ENSP00000483453|uniprotkb:A8MWU4	intact:EBI-447646|uniprotkb:O14564|uniprotkb:Q9NYN2|uniprotkb:Q9UPS2|uniprotkb:D3DWF0|ensembl:ENSP00000311962	psi-mi:synrg_human(display_long)|uniprotkb:SYNG(gene name synonym)|uniprotkb:Gamma-synergin(gene name synonym)|uniprotkb:AP1GBP1(gene name synonym)|uniprotkb:AP1 subunit gamma-binding protein 1(gene name synonym)|uniprotkb:SYNRG(gene name)|psi-mi:SYNRG(display_short)	psi-mi:gga2_human(display_long)|uniprotkb:Golgi-localized, gamma ear-containing, ARF-binding protein 2(gene name synonym)|uniprotkb:Gamma-adaptin-related protein 2(gene name synonym)|uniprotkb:VHS domain and ear domain of gamma-adaptin(gene name synonym)|uniprotkb:GGA2(gene name)|psi-mi:GGA2(display_short)|uniprotkb:KIAA1080(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hirst et al. (2000)	pubmed:10747088|mint:MINT-5212386	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7240526|mint:MINT-16928	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000610513|ensembl:ENSP00000478707|ensembl:ENSP00000483453|ensembl:ENST00000613407|ensembl:ENSP00000483152|ensembl:ENST00000614941|ensembl:ENSP00000481151|ensembl:ENST00000616179|ensembl:ENSP00000482962|ensembl:ENST00000618176|ensembl:ENSP00000482597|ensembl:ENSP00000480288|ensembl:ENST00000619541|ensembl:ENSP00000477885|ensembl:ENST00000621136|ensembl:ENSP00000484529|ensembl:ENST00000622045|ensembl:ENSP00000483063|ensembl:ENST00000632841|ensembl:ENSP00000487672|ensembl:ENST00000633429|ensembl:ENSP00000488473|refseq:NP_001157016.1|refseq:NP_542117.3|refseq:NP_001157019.1|refseq:NP_009178.3|refseq:NP_001157017.1|ensembl:ENSG00000274047(gene)|ensembl:ENSG00000275066(gene)|ensembl:ENST00000612223(transcript)|ensembl:ENST00000618402(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0030121"(AP-1 adaptor complex)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR011992(EF-Hand type)|interpro:IPR039656|rcsb pdb:2MX7|refseq:XP_016879582.1|refseq:NP_001157018.1|refseq:NP_942583.1|mint:MINT-414390(identity)	refseq:NP_055859.1|dip:DIP-31601N|ensembl:ENSG00000103365(gene)|ensembl:ENST00000309859(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR038425|interpro:IPR041198|mint:Q9UJY4|rcsb pdb:1MHQ|reactome:R-HSA-8854214|reactome:R-HSA-977225|mint:MINT-414393(identity)	-	comment:mint|function:"May play a role in endocytosis and/or membrane trafficking at the trans-Golgi network (TGN). May act by linking the adapter protein complex AP-1 to other proteins"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2001/10/02	2014/10/16	rogid:nsmKdl2koDl/Xk/bUBXCOFxrml49606	rogid:VD3+z3TdZr7Ius0oloo8bnMhwjQ9606	intact-crc:FE6183CE1FDF7278|rigid:VZ2D0fI/VbLbANccH044QqXSf7o	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15276	uniprotkb:Q9UJY4	intact:EBI-447043|uniprotkb:O95369|uniprotkb:Q8IVX3|uniprotkb:B2RAG7|ensembl:ENSP00000445408	intact:EBI-447646|uniprotkb:O14564|uniprotkb:Q9NYN2|uniprotkb:Q9UPS2|uniprotkb:D3DWF0|ensembl:ENSP00000311962	psi-mi:rabe1_human(display_long)|uniprotkb:Rabaptin-5(gene name synonym)|uniprotkb:Rabaptin-5alpha(gene name synonym)|uniprotkb:Rabaptin-4(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-17(gene name synonym)|uniprotkb:RABEP1(gene name)|psi-mi:RABEP1(display_short)|uniprotkb:RABPT5(gene name synonym)|uniprotkb:RABPT5A(gene name synonym)|uniprotkb:RAB5EP(gene name synonym)	psi-mi:gga2_human(display_long)|uniprotkb:Golgi-localized, gamma ear-containing, ARF-binding protein 2(gene name synonym)|uniprotkb:Gamma-adaptin-related protein 2(gene name synonym)|uniprotkb:VHS domain and ear domain of gamma-adaptin(gene name synonym)|uniprotkb:GGA2(gene name)|psi-mi:GGA2(display_short)|uniprotkb:KIAA1080(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hirst et al. (2000)	pubmed:10747088|mint:MINT-5212386	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7240562|mint:MINT-14026	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278510.1|refseq:NP_001077054.1|refseq:NP_004694.2|dip:DIP-29350N|go:"GO:0008083"(growth factor activity)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055037"(recycling endosome)|go:"GO:0061025"(membrane fusion)|go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR003914(Rabaptin)|interpro:IPR015390(Rabaptin, GTPase-Rab5 binding)|interpro:IPR018514|interpro:IPR029880|rcsb pdb:1P4U|rcsb pdb:1TU3|rcsb pdb:1X79|rcsb pdb:4N3Y|rcsb pdb:4N3Z|rcsb pdb:4Q9U|reactome:R-HSA-8854214|ensembl:ENSG00000029725(gene)|ensembl:ENST00000537505(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006915"(apoptotic process)|mint:MINT-414409(identity)	refseq:NP_055859.1|dip:DIP-31601N|ensembl:ENSG00000103365(gene)|ensembl:ENST00000309859(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR038425|interpro:IPR041198|mint:Q9UJY4|rcsb pdb:1MHQ|reactome:R-HSA-8854214|reactome:R-HSA-977225|mint:MINT-414406(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2001/10/02	2014/10/16	rogid:FDHgN8w6jbAPC3iQfeLY6sdLkrs9606	rogid:VD3+z3TdZr7Ius0oloo8bnMhwjQ9606	intact-crc:859ADA7C28109334|rigid:0rIkWRxHZXXOQQyQWIUz58BCd5o	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UMZ2	uniprotkb:Q9UJY5	intact:EBI-7240490|uniprotkb:Q6ZT17|uniprotkb:B7ZKZ3|uniprotkb:Q17RI2|uniprotkb:Q5BKU5|intact:MINT-126209|uniprotkb:B7ZKZ2|intact:EBI-28973092|ensembl:ENSP00000480288|ensembl:ENSP00000483453|uniprotkb:A8MWU4	intact:EBI-447141|uniprotkb:Q5TG07|uniprotkb:Q9BW94|uniprotkb:Q9UG00|uniprotkb:Q9UGW0|uniprotkb:Q9UGW1|uniprotkb:A8K3D3|uniprotkb:Q5R3N1|uniprotkb:Q6IC75|uniprotkb:B0QYR7|uniprotkb:Q86YA9|uniprotkb:Q8NCS6|ensembl:ENSP00000341344	psi-mi:synrg_human(display_long)|uniprotkb:SYNG(gene name synonym)|uniprotkb:Gamma-synergin(gene name synonym)|uniprotkb:AP1GBP1(gene name synonym)|uniprotkb:AP1 subunit gamma-binding protein 1(gene name synonym)|uniprotkb:SYNRG(gene name)|psi-mi:SYNRG(display_short)	psi-mi:gga1_human(display_long)|uniprotkb:Golgi-localized, gamma ear-containing, ARF-binding protein 1(gene name synonym)|uniprotkb:Gamma-adaptin-related protein 1(gene name synonym)|uniprotkb:GGA1(gene name)|psi-mi:GGA1(display_short)	psi-mi:"MI:0096"(pull down)	Hirst et al. (2000)	pubmed:10747088|mint:MINT-5212386	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7240552|mint:MINT-14654	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000610513|ensembl:ENSP00000478707|ensembl:ENSP00000483453|ensembl:ENST00000613407|ensembl:ENSP00000483152|ensembl:ENST00000614941|ensembl:ENSP00000481151|ensembl:ENST00000616179|ensembl:ENSP00000482962|ensembl:ENST00000618176|ensembl:ENSP00000482597|ensembl:ENSP00000480288|ensembl:ENST00000619541|ensembl:ENSP00000477885|ensembl:ENST00000621136|ensembl:ENSP00000484529|ensembl:ENST00000622045|ensembl:ENSP00000483063|ensembl:ENST00000632841|ensembl:ENSP00000487672|ensembl:ENST00000633429|ensembl:ENSP00000488473|refseq:NP_001157016.1|refseq:NP_542117.3|refseq:NP_001157019.1|refseq:NP_009178.3|refseq:NP_001157017.1|ensembl:ENSG00000274047(gene)|ensembl:ENSG00000275066(gene)|ensembl:ENST00000612223(transcript)|ensembl:ENST00000618402(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0030121"(AP-1 adaptor complex)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR011992(EF-Hand type)|interpro:IPR039656|rcsb pdb:2MX7|refseq:XP_016879582.1|refseq:NP_001157018.1|refseq:NP_942583.1|mint:MINT-414401(identity)	refseq:NP_001001560.1|refseq:NP_001166158.1|refseq:NP_001166159.1|refseq:NP_037497.1|refseq:XP_005261574.1|refseq:XP_011528424.1|refseq:XP_005261577.1|refseq:XP_006724292.1|refseq:XP_016884249.1|refseq:XP_016884250.1|refseq:XP_016884251.1|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:1901998"(toxin transport)|go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR038425|interpro:IPR041198|mint:Q9UJY5|rcsb pdb:1J2J|rcsb pdb:1JWF|rcsb pdb:1JWG|rcsb pdb:1NA8|rcsb pdb:1NAF|rcsb pdb:1NWM|rcsb pdb:1O3X|rcsb pdb:1OM9|rcsb pdb:1OXZ|rcsb pdb:1PY1|rcsb pdb:1UJJ|rcsb pdb:1UJK|rcsb pdb:1X79|rcsb pdb:2DWX|rcsb pdb:2DWY|rcsb pdb:3G2S|rcsb pdb:3G2T|rcsb pdb:3G2U|rcsb pdb:3G2V|rcsb pdb:3G2W|reactome:R-HSA-8854214|reactome:R-HSA-977225|ensembl:ENSG00000100083(gene)|ensembl:ENST00000343632(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008104"(protein localization)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|mint:MINT-414398(identity)	-	comment:mint|function:"May play a role in endocytosis and/or membrane trafficking at the trans-Golgi network (TGN). May act by linking the adapter protein complex AP-1 to other proteins"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2001/10/02	2014/10/16	rogid:nsmKdl2koDl/Xk/bUBXCOFxrml49606	rogid:3n7Nia4JzMiDja0I7mUcyihFFBc9606	intact-crc:F2BBD987C33BE3CE|rigid:4ngPqO8UWKyj+qWaN94zOANi7wk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)