#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P63209	uniprotkb:Q9Y297	intact:EBI-7114014|intact:MINT-108497|uniprotkb:Q8TAY2|uniprotkb:P34991	intact:EBI-307461|uniprotkb:Q9Y213|uniprotkb:B5MD49|uniprotkb:Q5W142|ensembl:ENSP00000359206|uniprotkb:Q5W141	psi-mi:skp1_cavpo(display_long)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:p19A(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:S-phase kinase-associated protein 1A(gene name synonym)	psi-mi:fbw1a_human(display_long)|uniprotkb:BTRC(gene name)|psi-mi:BTRC(display_short)|uniprotkb:BTRCP(gene name synonym)|uniprotkb:FBW1A(gene name synonym)|uniprotkb:FBXW1A(gene name synonym)|uniprotkb:F-box and WD repeats protein beta-TrCP(gene name synonym)|uniprotkb:E3RSIkappaB(gene name synonym)|uniprotkb:pIkappaBalpha-E3 receptor subunit(gene name synonym)|uniprotkb:Epididymis tissue protein Li 2a(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Cenciarelli et al. (1999)	pubmed:10531035|mint:MINT-5211921	taxid:10141(cavpo)|taxid:10141("Cavia porcellus (Guinea pig)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7114045|mint:MINT-13921	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR011333(BTB/POZ fold)|refseq:NP_001166486.1|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR001232(SKP1 component)|interpro:IPR036296|mint:MINT-375934(identity)	refseq:NP_003930.1|refseq:NP_378663.1|ensembl:ENSG00000166167(gene)|ensembl:ENST00000370187(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031648"(protein destabilization)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|interpro:IPR021977|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR036047|interpro:IPR036322|mint:Q9Y297|rcsb pdb:1P22|rcsb pdb:2P64|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|go:"GO:0046983"(protein dimerization activity)|rcsb pdb:6TTU|reactome:R-HSA-1169091|reactome:R-HSA-1170546|go:"GO:0048511"(rhythmic process)|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-195253|reactome:R-HSA-202424|go:"GO:0051726"(regulation of cell cycle)|reactome:R-HSA-2565942|reactome:R-HSA-2871837|reactome:R-HSA-3769402|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-983168|dip:DIP-31607N|mint:MINT-375937(identity)	-	comment:mint|function:"Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/02/03	2014/10/16	rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud010141	rogid:9/bXDY6YvJWvP6iMSgOPT9CNGAE9606	intact-crc:3CEE63AFC2FC5B61|rigid:/rBREMKTWEv9S/IwbGuknvv8WDM	false	-	binding-associated region:32-179(MINT-375938)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P63209	uniprotkb:Q9UKT5	intact:EBI-7114014|intact:MINT-108497|uniprotkb:Q8TAY2|uniprotkb:P34991	intact:EBI-960409|ensembl:ENSP00000281623|uniprotkb:Q68CU8|uniprotkb:Q86VT8|uniprotkb:Q9UK98	psi-mi:skp1_cavpo(display_long)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:p19A(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:S-phase kinase-associated protein 1A(gene name synonym)	psi-mi:fbx4_human(display_long)|uniprotkb:FBXO4(gene name)|psi-mi:FBXO4(display_short)|uniprotkb:FBX4(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Cenciarelli et al. (1999)	pubmed:10531035|mint:MINT-5211921	taxid:10141(cavpo)|taxid:10141("Cavia porcellus (Guinea pig)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7114140|mint:MINT-16854	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR011333(BTB/POZ fold)|refseq:NP_001166486.1|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR001232(SKP1 component)|interpro:IPR036296|mint:MINT-375985(identity)	ensembl:ENSG00000151876(gene)|ensembl:ENST00000281623(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007568"(aging)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035726"(common myeloid progenitor cell proliferation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR027417|interpro:IPR036047|go:"GO:0019005"(SCF ubiquitin ligase complex)|rcsb pdb:3L2O|rcsb pdb:3L82|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|interpro:IPR039588|refseq:NP_036308.1|refseq:NP_277019.1|mint:MINT-375988(identity)	-	comment:mint|function:"Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/02/03	2014/10/16	rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud010141	rogid:tCM4jv7DF/Wujdm2j3i95oknxaE9606	intact-crc:832F82DAC7336C8C|rigid:Z76qyKhdZSRIl2GnvGE1B2z4Obo	false	-	binding-associated region:55-98(MINT-375989)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P63209	uniprotkb:Q9UKT7	intact:EBI-7114014|intact:MINT-108497|uniprotkb:Q8TAY2|uniprotkb:P34991	intact:EBI-2557269|uniprotkb:Q9P122|uniprotkb:B2RB04|ensembl:ENSP00000347834	psi-mi:skp1_cavpo(display_long)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:p19A(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:S-phase kinase-associated protein 1A(gene name synonym)	psi-mi:fbxl3_human(display_long)|uniprotkb:FBL3A(gene name synonym)|uniprotkb:FBXL3A(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 3A(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 3A(gene name synonym)|uniprotkb:FBXL3(gene name)|psi-mi:FBXL3(display_short)	psi-mi:"MI:0019"(coimmunoprecipitation)	Cenciarelli et al. (1999)	pubmed:10531035|mint:MINT-5211921	taxid:10141(cavpo)|taxid:10141("Cavia porcellus (Guinea pig)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7114083|mint:MINT-16971	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR011333(BTB/POZ fold)|refseq:NP_001166486.1|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR001232(SKP1 component)|interpro:IPR036296|mint:MINT-375974(identity)	ensembl:ENSG00000005812(gene)|ensembl:ENST00000355619(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031648"(protein destabilization)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|reactome:R-HSA-390471|reactome:R-HSA-400253|reactome:R-HSA-8951664|reactome:R-HSA-983168|rcsb pdb:4I6J|refseq:NP_036290.1|refseq:XP_005266393.1|dip:DIP-40770N|mint:MINT-375977(identity)	-	comment:mint|function:"Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/02/03	2014/10/16	rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud010141	rogid:mD6wOlgnRmPCJbcVdLQnmcn+gkM9606	intact-crc:E0C37B8D7FA9F018|rigid:CqlZTRlulJlOlqFl3YqZNi63dY4	false	-	binding-associated region:40-76(MINT-375978)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P63209	uniprotkb:Q9UKT8	intact:EBI-7114014|intact:MINT-108497|uniprotkb:Q8TAY2|uniprotkb:P34991	intact:EBI-914727|uniprotkb:Q4VXH2|uniprotkb:Q7Z4V6|uniprotkb:Q8WV51|uniprotkb:Q9HA09|uniprotkb:Q9UKA3|uniprotkb:B3KRL8|ensembl:ENSP00000476369|ensembl:ENSP00000507010|ensembl:ENSP00000508157	psi-mi:skp1_cavpo(display_long)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:p19A(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:S-phase kinase-associated protein 1A(gene name synonym)	psi-mi:fbxw2_human(display_long)|uniprotkb:FBXW2(gene name)|psi-mi:FBXW2(display_short)|uniprotkb:FBW2(gene name synonym)|uniprotkb:FWD2(gene name synonym)|uniprotkb:F-box and WD-40 domain-containing protein 2(gene name synonym)|uniprotkb:Protein MD6(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Cenciarelli et al. (1999)	pubmed:10531035|mint:MINT-5211921	taxid:10141(cavpo)|taxid:10141("Cavia porcellus (Guinea pig)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7114170|mint:MINT-15782	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR011333(BTB/POZ fold)|refseq:NP_001166486.1|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR001232(SKP1 component)|interpro:IPR036296|mint:MINT-376030(identity)	refseq:NP_036296.2|refseq:XP_005251967.1|refseq:XP_016870104.1|dip:DIP-37972N|ensembl:ENSG00000119402(gene)|ensembl:ENST00000608872(transcript)|ensembl:ENST00000684001(transcript)|ensembl:ENST00000684047(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006508"(proteolysis)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036047|interpro:IPR036322|interpro:IPR042627|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|mint:MINT-376033(identity)	-	comment:mint|function:"Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/02/03	2014/10/16	rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud010141	rogid:SLs3xu8ssSvd7zsJ6gnpF/Is8ZE9606	intact-crc:6B34A8E207DE5A95|rigid:H+XKKUwhOYVop3nsxBSHQ4Kjix4	false	-	binding-associated region:60-101(MINT-376034)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P63209	uniprotkb:Q9Y3I1	intact:EBI-7114014|intact:MINT-108497|uniprotkb:Q8TAY2|uniprotkb:P34991	intact:EBI-1161222|uniprotkb:Q5TGC4|uniprotkb:Q96HM6|uniprotkb:Q9UF21|uniprotkb:Q9UKT2|uniprotkb:B4DNB3|ensembl:ENSP00000266087|uniprotkb:B4DWX5|uniprotkb:Q5TI86	psi-mi:skp1_cavpo(display_long)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:p19A(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:S-phase kinase-associated protein 1A(gene name synonym)	psi-mi:fbx7_human(display_long)|uniprotkb:FBXO7(gene name)|psi-mi:FBXO7(display_short)|uniprotkb:FBX7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Cenciarelli et al. (1999)	pubmed:10531035|mint:MINT-5211921	taxid:10141(cavpo)|taxid:10141("Cavia porcellus (Guinea pig)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7114208|mint:MINT-17107	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR011333(BTB/POZ fold)|refseq:NP_001166486.1|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR001232(SKP1 component)|interpro:IPR036296|mint:MINT-375947(identity)	refseq:NP_001028196.1|refseq:NP_036311.3|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045620"(negative regulation of lymphocyte differentiation)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0097409"(glial cytoplasmic inclusion)|go:"GO:0097414"(classical Lewy body)|go:"GO:0097462"(Lewy neurite)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1990037"(Lewy body core)|go:"GO:1990038"(Lewy body corona)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR021625|interpro:IPR029071|interpro:IPR036047|mint:Q9Y3I1|rcsb pdb:4L9C|rcsb pdb:4L9H|reactome:R-HSA-8951664|reactome:R-HSA-983168|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|ensembl:ENSG00000100225(gene)|ensembl:ENST00000266087(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|refseq:NP_001244919.1|dip:DIP-36125N|mint:MINT-375950(identity)	-	comment:mint|function:"Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2001/02/03	2014/10/16	rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud010141	rogid:i2Mqtw28fJTLURYC+gwr6bcjBoY9606	intact-crc:9FD0C4E41AACFA70|rigid:YcrxB55TU3FCDLL6dyfMg5P5Rx8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P63209	uniprotkb:Q9UKT8	intact:EBI-7114014|intact:MINT-108497|uniprotkb:Q8TAY2|uniprotkb:P34991	intact:EBI-914727|uniprotkb:Q4VXH2|uniprotkb:Q7Z4V6|uniprotkb:Q8WV51|uniprotkb:Q9HA09|uniprotkb:Q9UKA3|uniprotkb:B3KRL8|ensembl:ENSP00000476369|ensembl:ENSP00000507010|ensembl:ENSP00000508157	psi-mi:skp1_cavpo(display_long)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:p19A(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:S-phase kinase-associated protein 1A(gene name synonym)	psi-mi:fbxw2_human(display_long)|uniprotkb:FBXW2(gene name)|psi-mi:FBXW2(display_short)|uniprotkb:FBW2(gene name synonym)|uniprotkb:FWD2(gene name synonym)|uniprotkb:F-box and WD-40 domain-containing protein 2(gene name synonym)|uniprotkb:Protein MD6(gene name synonym)	psi-mi:"MI:0011"(beta lactamase complementation)	Cenciarelli et al. (1999)	pubmed:10531035|mint:MINT-5211921	taxid:10141(cavpo)|taxid:10141("Cavia porcellus (Guinea pig)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7114312|mint:MINT-15781	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR011333(BTB/POZ fold)|refseq:NP_001166486.1|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR001232(SKP1 component)|interpro:IPR036296|mint:MINT-375996(identity)	refseq:NP_036296.2|refseq:XP_005251967.1|refseq:XP_016870104.1|dip:DIP-37972N|ensembl:ENSG00000119402(gene)|ensembl:ENST00000608872(transcript)|ensembl:ENST00000684001(transcript)|ensembl:ENST00000684047(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006508"(proteolysis)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036047|interpro:IPR036322|interpro:IPR042627|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|mint:MINT-376002(identity)	-	comment:mint|function:"Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/02/03	2014/10/16	rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud010141	rogid:SLs3xu8ssSvd7zsJ6gnpF/Is8ZE9606	intact-crc:C37498B90814128B|rigid:H+XKKUwhOYVop3nsxBSHQ4Kjix4	false	tag:?-?(MINT-375997)	binding-associated region:60-101(MINT-376003)|tag:?-?(MINT-376006)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63209	uniprotkb:Q9Y297	intact:EBI-7114014|intact:MINT-108497|uniprotkb:Q8TAY2|uniprotkb:P34991	intact:EBI-307461|uniprotkb:Q9Y213|uniprotkb:B5MD49|uniprotkb:Q5W142|ensembl:ENSP00000359206|uniprotkb:Q5W141	psi-mi:skp1_cavpo(display_long)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:p19A(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:S-phase kinase-associated protein 1A(gene name synonym)	psi-mi:fbw1a_human(display_long)|uniprotkb:BTRC(gene name)|psi-mi:BTRC(display_short)|uniprotkb:BTRCP(gene name synonym)|uniprotkb:FBW1A(gene name synonym)|uniprotkb:FBXW1A(gene name synonym)|uniprotkb:F-box and WD repeats protein beta-TrCP(gene name synonym)|uniprotkb:E3RSIkappaB(gene name synonym)|uniprotkb:pIkappaBalpha-E3 receptor subunit(gene name synonym)|uniprotkb:Epididymis tissue protein Li 2a(gene name synonym)	psi-mi:"MI:0011"(beta lactamase complementation)	Cenciarelli et al. (1999)	pubmed:10531035|mint:MINT-5211921	taxid:10141(cavpo)|taxid:10141("Cavia porcellus (Guinea pig)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7114255|mint:MINT-13920	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR011333(BTB/POZ fold)|refseq:NP_001166486.1|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR001232(SKP1 component)|interpro:IPR036296|mint:MINT-375957(identity)	refseq:NP_003930.1|refseq:NP_378663.1|ensembl:ENSG00000166167(gene)|ensembl:ENST00000370187(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031648"(protein destabilization)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|interpro:IPR021977|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR036047|interpro:IPR036322|mint:Q9Y297|rcsb pdb:1P22|rcsb pdb:2P64|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|go:"GO:0046983"(protein dimerization activity)|rcsb pdb:6TTU|reactome:R-HSA-1169091|reactome:R-HSA-1170546|go:"GO:0048511"(rhythmic process)|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-195253|reactome:R-HSA-202424|go:"GO:0051726"(regulation of cell cycle)|reactome:R-HSA-2565942|reactome:R-HSA-2871837|reactome:R-HSA-3769402|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-983168|dip:DIP-31607N|mint:MINT-375963(identity)	-	comment:mint|function:"Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/02/03	2014/10/16	rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud010141	rogid:9/bXDY6YvJWvP6iMSgOPT9CNGAE9606	intact-crc:B298599A59C5A45E|rigid:/rBREMKTWEv9S/IwbGuknvv8WDM	false	tag:?-?(MINT-375958)	tag:?-?(MINT-375967)|binding-associated region:32-179(MINT-375964)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63209	uniprotkb:Q9UKT5	intact:EBI-7114014|intact:MINT-108497|uniprotkb:Q8TAY2|uniprotkb:P34991	intact:EBI-960409|ensembl:ENSP00000281623|uniprotkb:Q68CU8|uniprotkb:Q86VT8|uniprotkb:Q9UK98	psi-mi:skp1_cavpo(display_long)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:p19A(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:S-phase kinase-associated protein 1A(gene name synonym)	psi-mi:fbx4_human(display_long)|uniprotkb:FBXO4(gene name)|psi-mi:FBXO4(display_short)|uniprotkb:FBX4(gene name synonym)	psi-mi:"MI:0011"(beta lactamase complementation)	Cenciarelli et al. (1999)	pubmed:10531035|mint:MINT-5211921	taxid:10141(cavpo)|taxid:10141("Cavia porcellus (Guinea pig)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7114414|mint:MINT-16853	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR011333(BTB/POZ fold)|refseq:NP_001166486.1|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR001232(SKP1 component)|interpro:IPR036296|mint:MINT-376041(identity)	ensembl:ENSG00000151876(gene)|ensembl:ENST00000281623(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007568"(aging)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035726"(common myeloid progenitor cell proliferation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR027417|interpro:IPR036047|go:"GO:0019005"(SCF ubiquitin ligase complex)|rcsb pdb:3L2O|rcsb pdb:3L82|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|interpro:IPR039588|refseq:NP_036308.1|refseq:NP_277019.1|mint:MINT-376047(identity)	-	comment:mint|function:"Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/02/03	2014/10/16	rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud010141	rogid:tCM4jv7DF/Wujdm2j3i95oknxaE9606	intact-crc:39D7C923AE27C428|rigid:Z76qyKhdZSRIl2GnvGE1B2z4Obo	false	tag:?-?(MINT-376042)	binding-associated region:55-98(MINT-376048)|tag:?-?(MINT-376051)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63209	uniprotkb:Q9Y3I1	intact:EBI-7114014|intact:MINT-108497|uniprotkb:Q8TAY2|uniprotkb:P34991	intact:EBI-1161222|uniprotkb:Q5TGC4|uniprotkb:Q96HM6|uniprotkb:Q9UF21|uniprotkb:Q9UKT2|uniprotkb:B4DNB3|ensembl:ENSP00000266087|uniprotkb:B4DWX5|uniprotkb:Q5TI86	psi-mi:skp1_cavpo(display_long)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:p19A(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:S-phase kinase-associated protein 1A(gene name synonym)	psi-mi:fbx7_human(display_long)|uniprotkb:FBXO7(gene name)|psi-mi:FBXO7(display_short)|uniprotkb:FBX7(gene name synonym)	psi-mi:"MI:0011"(beta lactamase complementation)	Cenciarelli et al. (1999)	pubmed:10531035|mint:MINT-5211921	taxid:10141(cavpo)|taxid:10141("Cavia porcellus (Guinea pig)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7114434|mint:MINT-17106	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR011333(BTB/POZ fold)|refseq:NP_001166486.1|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR001232(SKP1 component)|interpro:IPR036296|mint:MINT-376058(identity)	refseq:NP_001028196.1|refseq:NP_036311.3|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045620"(negative regulation of lymphocyte differentiation)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0097409"(glial cytoplasmic inclusion)|go:"GO:0097414"(classical Lewy body)|go:"GO:0097462"(Lewy neurite)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1990037"(Lewy body core)|go:"GO:1990038"(Lewy body corona)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR021625|interpro:IPR029071|interpro:IPR036047|mint:Q9Y3I1|rcsb pdb:4L9C|rcsb pdb:4L9H|reactome:R-HSA-8951664|reactome:R-HSA-983168|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|ensembl:ENSG00000100225(gene)|ensembl:ENST00000266087(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|refseq:NP_001244919.1|dip:DIP-36125N|mint:MINT-376064(identity)	-	comment:mint|function:"Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/02/03	2014/10/16	rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud010141	rogid:i2Mqtw28fJTLURYC+gwr6bcjBoY9606	intact-crc:60B78FBF65FCD630|rigid:YcrxB55TU3FCDLL6dyfMg5P5Rx8	false	tag:?-?(MINT-376059)	tag:?-?(MINT-376065)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63209	uniprotkb:Q9UKT7	intact:EBI-7114014|intact:MINT-108497|uniprotkb:Q8TAY2|uniprotkb:P34991	intact:EBI-2557269|uniprotkb:Q9P122|uniprotkb:B2RB04|ensembl:ENSP00000347834	psi-mi:skp1_cavpo(display_long)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:p19A(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:S-phase kinase-associated protein 1A(gene name synonym)	psi-mi:fbxl3_human(display_long)|uniprotkb:FBL3A(gene name synonym)|uniprotkb:FBXL3A(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 3A(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 3A(gene name synonym)|uniprotkb:FBXL3(gene name)|psi-mi:FBXL3(display_short)	psi-mi:"MI:0011"(beta lactamase complementation)	Cenciarelli et al. (1999)	pubmed:10531035|mint:MINT-5211921	taxid:10141(cavpo)|taxid:10141("Cavia porcellus (Guinea pig)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7114348|mint:MINT-16970	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR011333(BTB/POZ fold)|refseq:NP_001166486.1|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR001232(SKP1 component)|interpro:IPR036296|mint:MINT-376013(identity)	ensembl:ENSG00000005812(gene)|ensembl:ENST00000355619(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031648"(protein destabilization)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|reactome:R-HSA-390471|reactome:R-HSA-400253|reactome:R-HSA-8951664|reactome:R-HSA-983168|rcsb pdb:4I6J|refseq:NP_036290.1|refseq:XP_005266393.1|dip:DIP-40770N|mint:MINT-376019(identity)	-	comment:mint|function:"Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/02/03	2014/10/16	rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud010141	rogid:mD6wOlgnRmPCJbcVdLQnmcn+gkM9606	intact-crc:7A90383FFEF23E3C|rigid:CqlZTRlulJlOlqFl3YqZNi63dY4	false	tag:?-?(MINT-376014)	binding-associated region:40-76(MINT-376020)|tag:?-?(MINT-376023)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)