#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P11433	uniprotkb:P18852	intact:EBI-4220|uniprotkb:D6VPH5|ensemblfungi:YAL041W	intact:EBI-7397|uniprotkb:D6VWQ5|ensemblfungi:YJR086W	psi-mi:cdc24_yeast(display_long)|uniprotkb:CLS4(gene name synonym)|uniprotkb:YAL041W(locus name)|uniprotkb:CDC24(gene name)|psi-mi:CDC24(display_short)|uniprotkb:Calcium regulatory protein(gene name synonym)	psi-mi:gbg_yeast(display_long)|uniprotkb:J1866(orf name)|uniprotkb:YJR086W(locus name)|uniprotkb:STE18(gene name)|psi-mi:STE18(display_short)	psi-mi:"MI:0018"(two hybrid)	Nern et al. (1999)	pubmed:10087263|mint:MINT-5211252|imex:IM-27298	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6964064|mint:MINT-17237|imex:IM-27298-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009359.1|sgd:S000000039|dip:DIP-2228N|mint:P11433|ensemblfungi:YAL041W(gene)|ensemblfungi:YAL041W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000935"(division septum)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043577"(chemotropism)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010481(CDC24 calponin)|interpro:IPR033511|interpro:IPR035899|interpro:IPR036872|rcsb pdb:1PQS|rcsb pdb:1Q1O|rcsb pdb:1TZ1|rcsb pdb:2KFJ|rcsb pdb:2KFK	refseq:NP_012619.1|sgd:S000003846|dip:DIP-314N|ensemblfungi:YJR086W(gene)|ensemblfungi:YJR086W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0071944"(cell periphery)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|interpro:IPR015898(G-protein, gamma-like subunit)|interpro:IPR036284|interpro:IPR041848|rcsb pdb:1SCG	-	crc64:856BCAF4EB0A67D1	-	figure legend:Fig. 1|comment:Haploid strain|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2001/02/12	2015/07/23	rogid:Q9eflcLn4oOOeRZ4tTjHrPguDUc559292	rogid:qAQ9+amYOEzrDzpb0RzbjvEDqTI559292	intact-crc:759B5B118F17F7A2|rigid:ZcH2z9ZgfEmL3pG/uJYLi67uz4w	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P11433	uniprotkb:P21268	intact:EBI-4220|uniprotkb:D6VPH5|ensemblfungi:YAL041W	intact:EBI-6780|uniprotkb:D6VW30|ensemblfungi:YJL157C	psi-mi:cdc24_yeast(display_long)|uniprotkb:CLS4(gene name synonym)|uniprotkb:YAL041W(locus name)|uniprotkb:CDC24(gene name)|psi-mi:CDC24(display_short)|uniprotkb:Calcium regulatory protein(gene name synonym)	psi-mi:far1_yeast(display_long)|uniprotkb:FAR1(gene name)|psi-mi:FAR1(display_short)|uniprotkb:YJL157C(locus name)|uniprotkb:J0565(orf name)|uniprotkb:Factor arrest protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Nern et al. (1999)	pubmed:10087263|mint:MINT-5211252|imex:IM-27298	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6964064|mint:MINT-17237|imex:IM-27298-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009359.1|sgd:S000000039|dip:DIP-2228N|mint:P11433|ensemblfungi:YAL041W(gene)|ensemblfungi:YAL041W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000935"(division septum)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043577"(chemotropism)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010481(CDC24 calponin)|interpro:IPR033511|interpro:IPR035899|interpro:IPR036872|rcsb pdb:1PQS|rcsb pdb:1Q1O|rcsb pdb:1TZ1|rcsb pdb:2KFJ|rcsb pdb:2KFK	refseq:NP_012378.1|sgd:S000003693|dip:DIP-2229N|ensemblfungi:YJL157C(gene)|ensemblfungi:YJL157C_mRNA(transcript)|go:"GO:0000751"(mitotic cell cycle G1 arrest in response to pheromone)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0043332"(mating projection tip)|go:"GO:0043577"(chemotropism)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|interpro:IPR001841(Zinc finger, RING-type)|mint:MINT-364804(identity)	-	crc64:856BCAF4EB0A67D1	crc64:834EBB2D7BB9641D|comment:"Stoichiometry: 1.0"	figure legend:Fig. 1|comment:Haploid strain|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2001/02/12	2015/07/23	rogid:Q9eflcLn4oOOeRZ4tTjHrPguDUc559292	rogid:rTJ2ff6oVexivzYXN/1ig1IZkkg559292	intact-crc:759B5B118F17F7A2|rigid:ZcH2z9ZgfEmL3pG/uJYLi67uz4w	false	-	tag:?-?(MINT-364805)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11433	uniprotkb:P18851	intact:EBI-4220|uniprotkb:D6VPH5|ensemblfungi:YAL041W	intact:EBI-7390|uniprotkb:D6W2R8|ensemblfungi:YOR212W	psi-mi:cdc24_yeast(display_long)|uniprotkb:CLS4(gene name synonym)|uniprotkb:YAL041W(locus name)|uniprotkb:CDC24(gene name)|psi-mi:CDC24(display_short)|uniprotkb:Calcium regulatory protein(gene name synonym)	psi-mi:gbb_yeast(display_long)|uniprotkb:YOR50-2(orf name)|uniprotkb:YOR212W(locus name)|uniprotkb:STE4(gene name)|psi-mi:STE4(display_short)	psi-mi:"MI:0018"(two hybrid)	Nern et al. (1999)	pubmed:10087263|mint:MINT-5211252|imex:IM-27298	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6964064|mint:MINT-17237|imex:IM-27298-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009359.1|sgd:S000000039|dip:DIP-2228N|mint:P11433|ensemblfungi:YAL041W(gene)|ensemblfungi:YAL041W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000935"(division septum)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043577"(chemotropism)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010481(CDC24 calponin)|interpro:IPR033511|interpro:IPR035899|interpro:IPR036872|rcsb pdb:1PQS|rcsb pdb:1Q1O|rcsb pdb:1TZ1|rcsb pdb:2KFJ|rcsb pdb:2KFK	sgd:S000005738|refseq:NP_014855.3|mint:P18851|dip:DIP-954N|ensemblfungi:YOR212W(gene)|ensemblfungi:YOR212W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005937"(mating projection)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0043577"(chemotropism)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|go:"GO:1903260"(protein localization to mating projection tip)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:1SCG|reactome:R-SCE-6814122|mint:MINT-364810(identity)	-	crc64:856BCAF4EB0A67D1	crc64:4B0E26040AAA83E5|comment:"Stoichiometry: 1.0"	figure legend:Fig. 1|comment:Haploid strain|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2001/02/12	2015/07/23	rogid:Q9eflcLn4oOOeRZ4tTjHrPguDUc559292	rogid:nDgadSWQPcmSvQlIEjpNHPl3Hjc559292	intact-crc:759B5B118F17F7A2|rigid:ZcH2z9ZgfEmL3pG/uJYLi67uz4w	false	-	tag:?-?(MINT-364811)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P18851	uniprotkb:P18852	intact:EBI-7390|uniprotkb:D6W2R8|ensemblfungi:YOR212W	intact:EBI-7397|uniprotkb:D6VWQ5|ensemblfungi:YJR086W	psi-mi:gbb_yeast(display_long)|uniprotkb:YOR50-2(orf name)|uniprotkb:YOR212W(locus name)|uniprotkb:STE4(gene name)|psi-mi:STE4(display_short)	psi-mi:gbg_yeast(display_long)|uniprotkb:J1866(orf name)|uniprotkb:YJR086W(locus name)|uniprotkb:STE18(gene name)|psi-mi:STE18(display_short)	psi-mi:"MI:0018"(two hybrid)	Nern et al. (1999)	pubmed:10087263|mint:MINT-5211252|imex:IM-27298	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-10919898|imex:IM-27298-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005738|refseq:NP_014855.3|mint:P18851|dip:DIP-954N|ensemblfungi:YOR212W(gene)|ensemblfungi:YOR212W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005937"(mating projection)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0043577"(chemotropism)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|go:"GO:1903260"(protein localization to mating projection tip)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:1SCG|reactome:R-SCE-6814122|mint:MINT-364810(identity)	refseq:NP_012619.1|sgd:S000003846|dip:DIP-314N|ensemblfungi:YJR086W(gene)|ensemblfungi:YJR086W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0071944"(cell periphery)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|interpro:IPR015898(G-protein, gamma-like subunit)|interpro:IPR036284|interpro:IPR041848|rcsb pdb:1SCG	-	crc64:4B0E26040AAA83E5|comment:"Stoichiometry: 1.0"	-	figure legend:Fig. 1|comment:Haploid strain|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2001/02/12	2015/07/23	rogid:nDgadSWQPcmSvQlIEjpNHPl3Hjc559292	rogid:qAQ9+amYOEzrDzpb0RzbjvEDqTI559292	rigid:/UxWk8B0EWGJSCx+gmePGJgBNXw	false	tag:?-?(MINT-364811)	tag:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P11433	uniprotkb:P21268	intact:EBI-4220|uniprotkb:D6VPH5|ensemblfungi:YAL041W	intact:EBI-6780|uniprotkb:D6VW30|ensemblfungi:YJL157C	psi-mi:cdc24_yeast(display_long)|uniprotkb:CLS4(gene name synonym)|uniprotkb:YAL041W(locus name)|uniprotkb:CDC24(gene name)|psi-mi:CDC24(display_short)|uniprotkb:Calcium regulatory protein(gene name synonym)	psi-mi:far1_yeast(display_long)|uniprotkb:FAR1(gene name)|psi-mi:FAR1(display_short)|uniprotkb:YJL157C(locus name)|uniprotkb:J0565(orf name)|uniprotkb:Factor arrest protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Nern et al. (1999)	pubmed:10087263|mint:MINT-5211252|imex:IM-27298	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-10919910|imex:IM-27298-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009359.1|sgd:S000000039|dip:DIP-2228N|mint:P11433|ensemblfungi:YAL041W(gene)|ensemblfungi:YAL041W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000935"(division septum)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043577"(chemotropism)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010481(CDC24 calponin)|interpro:IPR033511|interpro:IPR035899|interpro:IPR036872|rcsb pdb:1PQS|rcsb pdb:1Q1O|rcsb pdb:1TZ1|rcsb pdb:2KFJ|rcsb pdb:2KFK	refseq:NP_012378.1|sgd:S000003693|dip:DIP-2229N|ensemblfungi:YJL157C(gene)|ensemblfungi:YJL157C_mRNA(transcript)|go:"GO:0000751"(mitotic cell cycle G1 arrest in response to pheromone)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0043332"(mating projection tip)|go:"GO:0043577"(chemotropism)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|interpro:IPR001841(Zinc finger, RING-type)|mint:MINT-364804(identity)	-	crc64:856BCAF4EB0A67D1	crc64:834EBB2D7BB9641D|comment:"Stoichiometry: 1.0"	figure legend:Fig. 1, Table II|comment:Haploid and diploid strains|comment:Deletion of FAR1 resulted in a loss of the Cdc24p–Ste4 interaction which was not restored upon overexpression of Ste18|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2001/02/12	2015/07/23	rogid:Q9eflcLn4oOOeRZ4tTjHrPguDUc559292	rogid:rTJ2ff6oVexivzYXN/1ig1IZkkg559292	rigid:3VopJFaSfiLiPsdy3Hv0Z5OxQf8	false	tag:?-?	necessary binding region:757-830	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11433	uniprotkb:P18851	intact:EBI-4220|uniprotkb:D6VPH5|ensemblfungi:YAL041W	intact:EBI-7390|uniprotkb:D6W2R8|ensemblfungi:YOR212W	psi-mi:cdc24_yeast(display_long)|uniprotkb:CLS4(gene name synonym)|uniprotkb:YAL041W(locus name)|uniprotkb:CDC24(gene name)|psi-mi:CDC24(display_short)|uniprotkb:Calcium regulatory protein(gene name synonym)	psi-mi:gbb_yeast(display_long)|uniprotkb:YOR50-2(orf name)|uniprotkb:YOR212W(locus name)|uniprotkb:STE4(gene name)|psi-mi:STE4(display_short)	psi-mi:"MI:0018"(two hybrid)	Nern et al. (1999)	pubmed:10087263|mint:MINT-5211252|imex:IM-27298	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-10919910|imex:IM-27298-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009359.1|sgd:S000000039|dip:DIP-2228N|mint:P11433|ensemblfungi:YAL041W(gene)|ensemblfungi:YAL041W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000935"(division septum)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043577"(chemotropism)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010481(CDC24 calponin)|interpro:IPR033511|interpro:IPR035899|interpro:IPR036872|rcsb pdb:1PQS|rcsb pdb:1Q1O|rcsb pdb:1TZ1|rcsb pdb:2KFJ|rcsb pdb:2KFK	sgd:S000005738|refseq:NP_014855.3|mint:P18851|dip:DIP-954N|ensemblfungi:YOR212W(gene)|ensemblfungi:YOR212W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005937"(mating projection)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0043577"(chemotropism)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|go:"GO:1903260"(protein localization to mating projection tip)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:1SCG|reactome:R-SCE-6814122|mint:MINT-364810(identity)	-	crc64:856BCAF4EB0A67D1	crc64:4B0E26040AAA83E5|comment:"Stoichiometry: 1.0"	figure legend:Fig. 1, Table II|comment:Haploid and diploid strains|comment:Deletion of FAR1 resulted in a loss of the Cdc24p–Ste4 interaction which was not restored upon overexpression of Ste18|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2001/02/12	2015/07/23	rogid:Q9eflcLn4oOOeRZ4tTjHrPguDUc559292	rogid:nDgadSWQPcmSvQlIEjpNHPl3Hjc559292	rigid:3VopJFaSfiLiPsdy3Hv0Z5OxQf8	false	tag:?-?	tag:?-?(MINT-364811)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11433	uniprotkb:P21268	intact:EBI-4220|uniprotkb:D6VPH5|ensemblfungi:YAL041W	intact:EBI-6780|uniprotkb:D6VW30|ensemblfungi:YJL157C	psi-mi:cdc24_yeast(display_long)|uniprotkb:CLS4(gene name synonym)|uniprotkb:YAL041W(locus name)|uniprotkb:CDC24(gene name)|psi-mi:CDC24(display_short)|uniprotkb:Calcium regulatory protein(gene name synonym)	psi-mi:far1_yeast(display_long)|uniprotkb:FAR1(gene name)|psi-mi:FAR1(display_short)|uniprotkb:YJL157C(locus name)|uniprotkb:J0565(orf name)|uniprotkb:Factor arrest protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Nern et al. (1999)	pubmed:10087263|mint:MINT-5211252|imex:IM-27298	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-10950633|imex:IM-27298-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009359.1|sgd:S000000039|dip:DIP-2228N|mint:P11433|ensemblfungi:YAL041W(gene)|ensemblfungi:YAL041W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000935"(division septum)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043577"(chemotropism)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010481(CDC24 calponin)|interpro:IPR033511|interpro:IPR035899|interpro:IPR036872|rcsb pdb:1PQS|rcsb pdb:1Q1O|rcsb pdb:1TZ1|rcsb pdb:2KFJ|rcsb pdb:2KFK	refseq:NP_012378.1|sgd:S000003693|dip:DIP-2229N|ensemblfungi:YJL157C(gene)|ensemblfungi:YJL157C_mRNA(transcript)|go:"GO:0000751"(mitotic cell cycle G1 arrest in response to pheromone)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0043332"(mating projection tip)|go:"GO:0043577"(chemotropism)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|interpro:IPR001841(Zinc finger, RING-type)|mint:MINT-364804(identity)	-	crc64:856BCAF4EB0A67D1	crc64:834EBB2D7BB9641D|comment:"Stoichiometry: 1.0"	figure legend:Table III|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2001/02/12	2015/07/30	rogid:Q9eflcLn4oOOeRZ4tTjHrPguDUc559292	rogid:rTJ2ff6oVexivzYXN/1ig1IZkkg559292	rigid:pqSflQF9C1QFTb+bmVYUUPAUEb4	false	tag:?-?	tag:?-?(MINT-364805)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P21268	uniprotkb:P18851	intact:EBI-6780|uniprotkb:D6VW30|ensemblfungi:YJL157C	intact:EBI-7390|uniprotkb:D6W2R8|ensemblfungi:YOR212W	psi-mi:far1_yeast(display_long)|uniprotkb:FAR1(gene name)|psi-mi:FAR1(display_short)|uniprotkb:YJL157C(locus name)|uniprotkb:J0565(orf name)|uniprotkb:Factor arrest protein(gene name synonym)	psi-mi:gbb_yeast(display_long)|uniprotkb:YOR50-2(orf name)|uniprotkb:YOR212W(locus name)|uniprotkb:STE4(gene name)|psi-mi:STE4(display_short)	psi-mi:"MI:0018"(two hybrid)	Nern et al. (1999)	pubmed:10087263|mint:MINT-5211252|imex:IM-27298	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-10950662|imex:IM-27298-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012378.1|sgd:S000003693|dip:DIP-2229N|ensemblfungi:YJL157C(gene)|ensemblfungi:YJL157C_mRNA(transcript)|go:"GO:0000751"(mitotic cell cycle G1 arrest in response to pheromone)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0043332"(mating projection tip)|go:"GO:0043577"(chemotropism)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|interpro:IPR001841(Zinc finger, RING-type)|mint:MINT-364804(identity)	sgd:S000005738|refseq:NP_014855.3|mint:P18851|dip:DIP-954N|ensemblfungi:YOR212W(gene)|ensemblfungi:YOR212W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005937"(mating projection)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0043577"(chemotropism)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|go:"GO:1903260"(protein localization to mating projection tip)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:1SCG|reactome:R-SCE-6814122|mint:MINT-364810(identity)	-	crc64:834EBB2D7BB9641D|comment:"Stoichiometry: 1.0"	crc64:4B0E26040AAA83E5|comment:"Stoichiometry: 1.0"	figure legend:Table III|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2001/02/12	2015/07/30	rogid:rTJ2ff6oVexivzYXN/1ig1IZkkg559292	rogid:nDgadSWQPcmSvQlIEjpNHPl3Hjc559292	rigid:GuswAqpmJpR8y0irjE6/g6gOjyM	false	tag:?-?(MINT-364805)	tag:?-?(MINT-364811)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11433	uniprotkb:P21268	intact:EBI-4220|uniprotkb:D6VPH5|ensemblfungi:YAL041W	intact:EBI-6780|uniprotkb:D6VW30|ensemblfungi:YJL157C	psi-mi:cdc24_yeast(display_long)|uniprotkb:CLS4(gene name synonym)|uniprotkb:YAL041W(locus name)|uniprotkb:CDC24(gene name)|psi-mi:CDC24(display_short)|uniprotkb:Calcium regulatory protein(gene name synonym)	psi-mi:far1_yeast(display_long)|uniprotkb:FAR1(gene name)|psi-mi:FAR1(display_short)|uniprotkb:YJL157C(locus name)|uniprotkb:J0565(orf name)|uniprotkb:Factor arrest protein(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Nern et al. (1999)	pubmed:10087263|mint:MINT-5211252|imex:IM-27298	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-10950695|imex:IM-27298-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009359.1|sgd:S000000039|dip:DIP-2228N|mint:P11433|ensemblfungi:YAL041W(gene)|ensemblfungi:YAL041W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000935"(division septum)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043577"(chemotropism)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010481(CDC24 calponin)|interpro:IPR033511|interpro:IPR035899|interpro:IPR036872|rcsb pdb:1PQS|rcsb pdb:1Q1O|rcsb pdb:1TZ1|rcsb pdb:2KFJ|rcsb pdb:2KFK	refseq:NP_012378.1|sgd:S000003693|dip:DIP-2229N|ensemblfungi:YJL157C(gene)|ensemblfungi:YJL157C_mRNA(transcript)|go:"GO:0000751"(mitotic cell cycle G1 arrest in response to pheromone)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0043332"(mating projection tip)|go:"GO:0043577"(chemotropism)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|interpro:IPR001841(Zinc finger, RING-type)|mint:MINT-364804(identity)	-	crc64:856BCAF4EB0A67D1	crc64:834EBB2D7BB9641D|comment:"Stoichiometry: 1.0"	figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2001/02/12	2015/07/30	rogid:Q9eflcLn4oOOeRZ4tTjHrPguDUc559292	rogid:rTJ2ff6oVexivzYXN/1ig1IZkkg559292	rigid:pqSflQF9C1QFTb+bmVYUUPAUEb4	false	myc tag:n-n	protein a tag:?-?(MINT-364805)|necessary binding region:757-830	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P11433	uniprotkb:P21268	intact:EBI-4220|uniprotkb:D6VPH5|ensemblfungi:YAL041W	intact:EBI-6780|uniprotkb:D6VW30|ensemblfungi:YJL157C	psi-mi:cdc24_yeast(display_long)|uniprotkb:CLS4(gene name synonym)|uniprotkb:YAL041W(locus name)|uniprotkb:CDC24(gene name)|psi-mi:CDC24(display_short)|uniprotkb:Calcium regulatory protein(gene name synonym)	psi-mi:far1_yeast(display_long)|uniprotkb:FAR1(gene name)|psi-mi:FAR1(display_short)|uniprotkb:YJL157C(locus name)|uniprotkb:J0565(orf name)|uniprotkb:Factor arrest protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Nern et al. (1999)	pubmed:10087263|mint:MINT-5211252|imex:IM-27298	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-10950747|imex:IM-27298-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009359.1|sgd:S000000039|dip:DIP-2228N|mint:P11433|ensemblfungi:YAL041W(gene)|ensemblfungi:YAL041W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000935"(division septum)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043577"(chemotropism)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010481(CDC24 calponin)|interpro:IPR033511|interpro:IPR035899|interpro:IPR036872|rcsb pdb:1PQS|rcsb pdb:1Q1O|rcsb pdb:1TZ1|rcsb pdb:2KFJ|rcsb pdb:2KFK	refseq:NP_012378.1|sgd:S000003693|dip:DIP-2229N|ensemblfungi:YJL157C(gene)|ensemblfungi:YJL157C_mRNA(transcript)|go:"GO:0000751"(mitotic cell cycle G1 arrest in response to pheromone)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0043332"(mating projection tip)|go:"GO:0043577"(chemotropism)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|interpro:IPR001841(Zinc finger, RING-type)|mint:MINT-364804(identity)	-	crc64:856BCAF4EB0A67D1	crc64:834EBB2D7BB9641D|comment:"Stoichiometry: 1.0"	figure legend:Fig. 3, 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2001/02/12	2015/07/30	rogid:Q9eflcLn4oOOeRZ4tTjHrPguDUc559292	rogid:rTJ2ff6oVexivzYXN/1ig1IZkkg559292	rigid:pqSflQF9C1QFTb+bmVYUUPAUEb4	false	glutathione s tranferase tag:n-n|sufficient binding region:1-472	maltose binding protein tag:?-?(MINT-364805)|necessary binding region:757-830	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P21268	uniprotkb:P18851	intact:EBI-6780|uniprotkb:D6VW30|ensemblfungi:YJL157C	intact:EBI-7390|uniprotkb:D6W2R8|ensemblfungi:YOR212W	psi-mi:far1_yeast(display_long)|uniprotkb:FAR1(gene name)|psi-mi:FAR1(display_short)|uniprotkb:YJL157C(locus name)|uniprotkb:J0565(orf name)|uniprotkb:Factor arrest protein(gene name synonym)	psi-mi:gbb_yeast(display_long)|uniprotkb:YOR50-2(orf name)|uniprotkb:YOR212W(locus name)|uniprotkb:STE4(gene name)|psi-mi:STE4(display_short)	psi-mi:"MI:0096"(pull down)	Nern et al. (1999)	pubmed:10087263|mint:MINT-5211252|imex:IM-27298	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-10950802|imex:IM-27298-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012378.1|sgd:S000003693|dip:DIP-2229N|ensemblfungi:YJL157C(gene)|ensemblfungi:YJL157C_mRNA(transcript)|go:"GO:0000751"(mitotic cell cycle G1 arrest in response to pheromone)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0043332"(mating projection tip)|go:"GO:0043577"(chemotropism)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|interpro:IPR001841(Zinc finger, RING-type)|mint:MINT-364804(identity)	sgd:S000005738|refseq:NP_014855.3|mint:P18851|dip:DIP-954N|ensemblfungi:YOR212W(gene)|ensemblfungi:YOR212W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005937"(mating projection)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0043577"(chemotropism)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|go:"GO:1903260"(protein localization to mating projection tip)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:1SCG|reactome:R-SCE-6814122|mint:MINT-364810(identity)	-	crc64:834EBB2D7BB9641D|comment:"Stoichiometry: 1.0"	crc64:4B0E26040AAA83E5|comment:"Stoichiometry: 1.0"	figure legend:Fig.4C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2001/02/12	2015/07/30	rogid:rTJ2ff6oVexivzYXN/1ig1IZkkg559292	rogid:nDgadSWQPcmSvQlIEjpNHPl3Hjc559292	rigid:GuswAqpmJpR8y0irjE6/g6gOjyM	false	sufficient binding region:133-297|maltose binding protein tag:?-?(MINT-364805)	ha tag:n-n(MINT-364811)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P11433	uniprotkb:P18851	intact:EBI-4220|uniprotkb:D6VPH5|ensemblfungi:YAL041W	intact:EBI-7390|uniprotkb:D6W2R8|ensemblfungi:YOR212W	psi-mi:cdc24_yeast(display_long)|uniprotkb:CLS4(gene name synonym)|uniprotkb:YAL041W(locus name)|uniprotkb:CDC24(gene name)|psi-mi:CDC24(display_short)|uniprotkb:Calcium regulatory protein(gene name synonym)	psi-mi:gbb_yeast(display_long)|uniprotkb:YOR50-2(orf name)|uniprotkb:YOR212W(locus name)|uniprotkb:STE4(gene name)|psi-mi:STE4(display_short)	psi-mi:"MI:0096"(pull down)	Nern et al. (1999)	pubmed:10087263|mint:MINT-5211252|imex:IM-27298	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-10950846|imex:IM-27298-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009359.1|sgd:S000000039|dip:DIP-2228N|mint:P11433|ensemblfungi:YAL041W(gene)|ensemblfungi:YAL041W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000935"(division septum)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043577"(chemotropism)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010481(CDC24 calponin)|interpro:IPR033511|interpro:IPR035899|interpro:IPR036872|rcsb pdb:1PQS|rcsb pdb:1Q1O|rcsb pdb:1TZ1|rcsb pdb:2KFJ|rcsb pdb:2KFK	sgd:S000005738|refseq:NP_014855.3|mint:P18851|dip:DIP-954N|ensemblfungi:YOR212W(gene)|ensemblfungi:YOR212W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005937"(mating projection)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0043577"(chemotropism)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|go:"GO:1903260"(protein localization to mating projection tip)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:1SCG|reactome:R-SCE-6814122	-	crc64:856BCAF4EB0A67D1	crc64:4B0E26040AAA83E5	figure legend:Fig. 5|comment:GSTCdc24– MBPFar1 was isolated by sequential purification using amylose and glutathione resin. Purified HASte4p was then incubated either with this complex or GSTCdc24 alone|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2001/02/12	2015/07/30	rogid:Q9eflcLn4oOOeRZ4tTjHrPguDUc559292	rogid:nDgadSWQPcmSvQlIEjpNHPl3Hjc559292	rigid:3VopJFaSfiLiPsdy3Hv0Z5OxQf8	false	glutathione s tranferase tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P11433	uniprotkb:P21268	intact:EBI-4220|uniprotkb:D6VPH5|ensemblfungi:YAL041W	intact:EBI-6780|uniprotkb:D6VW30|ensemblfungi:YJL157C	psi-mi:cdc24_yeast(display_long)|uniprotkb:CLS4(gene name synonym)|uniprotkb:YAL041W(locus name)|uniprotkb:CDC24(gene name)|psi-mi:CDC24(display_short)|uniprotkb:Calcium regulatory protein(gene name synonym)	psi-mi:far1_yeast(display_long)|uniprotkb:FAR1(gene name)|psi-mi:FAR1(display_short)|uniprotkb:YJL157C(locus name)|uniprotkb:J0565(orf name)|uniprotkb:Factor arrest protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Nern et al. (1999)	pubmed:10087263|mint:MINT-5211252|imex:IM-27298	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-10950846|imex:IM-27298-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009359.1|sgd:S000000039|dip:DIP-2228N|mint:P11433|ensemblfungi:YAL041W(gene)|ensemblfungi:YAL041W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0000935"(division septum)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043577"(chemotropism)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010481(CDC24 calponin)|interpro:IPR033511|interpro:IPR035899|interpro:IPR036872|rcsb pdb:1PQS|rcsb pdb:1Q1O|rcsb pdb:1TZ1|rcsb pdb:2KFJ|rcsb pdb:2KFK	refseq:NP_012378.1|sgd:S000003693|dip:DIP-2229N|ensemblfungi:YJL157C(gene)|ensemblfungi:YJL157C_mRNA(transcript)|go:"GO:0000751"(mitotic cell cycle G1 arrest in response to pheromone)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0043332"(mating projection tip)|go:"GO:0043577"(chemotropism)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|interpro:IPR001841(Zinc finger, RING-type)|mint:MINT-364804(identity)	-	crc64:856BCAF4EB0A67D1	crc64:834EBB2D7BB9641D|comment:"Stoichiometry: 1.0"	figure legend:Fig. 5|comment:GSTCdc24– MBPFar1 was isolated by sequential purification using amylose and glutathione resin. Purified HASte4p was then incubated either with this complex or GSTCdc24 alone|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2001/02/12	2015/07/30	rogid:Q9eflcLn4oOOeRZ4tTjHrPguDUc559292	rogid:rTJ2ff6oVexivzYXN/1ig1IZkkg559292	rigid:3VopJFaSfiLiPsdy3Hv0Z5OxQf8	false	glutathione s tranferase tag:n-n	maltose binding protein tag:?-?(MINT-364805)|necessary binding region:757-830	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)