#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P26696	uniprotkb:P10665	intact:EBI-6957733|uniprotkb:Q5D061|intact:MINT-86973	intact:EBI-6957709|uniprotkb:Q6DE78|intact:MINT-86963	psi-mi:mk01_xenla(display_long)|uniprotkb:mapk1(gene name)|psi-mi:mapk1(display_short)|uniprotkb:mpk1(gene name synonym)|uniprotkb:Myelin xP42 protein kinase(gene name synonym)|uniprotkb:Myelin basic protein kinase(gene name synonym)|uniprotkb:M phase MAP kinase(gene name synonym)	psi-mi:ks6aa_xenla(display_long)|uniprotkb:rps6ka(gene name)|psi-mi:rps6ka(display_short)|uniprotkb:Ribosomal protein S6 kinase II alpha(gene name synonym)|uniprotkb:MAP kinase-activated protein kinase 1(gene name synonym)|uniprotkb:p90-RSK(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Gavin et al. (1999)	pubmed:10074458|mint:MINT-5211221	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6957764|mint:MINT-15784	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_001083548.1|interpro:IPR011009(Protein kinase-like)|mint:MINT-364408(identity)	go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR016239(Ribosomal protein S6 kinase II)|interpro:IPR017892|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR011009(Protein kinase-like)|refseq:NP_001085310.1|interpro:IPR041906|mint:MINT-364400(identity)	-	comment:mint|function:"Phosphorylates microtubule-associated protein 2 (MAP2). Myelin basic protein (MBP), and Elk-1; may promote entry in the cell cycle. Activated by M phase promoting factor (MPF)"|comment:"Stoichiometry: 1.0"	function:Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of transcription|comment:mint|comment:"Stoichiometry: 1.0"	comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/03/30	2014/10/16	rogid:pVsO+47tJOR2yAYrvuLVW4sJoDg8355	rogid:kmeawN9mJF+B514TVG+cmspnXCk8355	intact-crc:C3CEAA86E88E62E7|rigid:nkkpqxKRjgOHDlOFZ96NAONhfU0	false	tag:?-?(MINT-364409)	binding-associated region:709-733(MINT-364401)|tag:?-?(MINT-364403)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P10665	uniprotkb:P26696	intact:EBI-6957709|uniprotkb:Q6DE78|intact:MINT-86963	intact:EBI-6957733|uniprotkb:Q5D061|intact:MINT-86973	psi-mi:ks6aa_xenla(display_long)|uniprotkb:rps6ka(gene name)|psi-mi:rps6ka(display_short)|uniprotkb:Ribosomal protein S6 kinase II alpha(gene name synonym)|uniprotkb:MAP kinase-activated protein kinase 1(gene name synonym)|uniprotkb:p90-RSK(gene name synonym)	psi-mi:mk01_xenla(display_long)|uniprotkb:mapk1(gene name)|psi-mi:mapk1(display_short)|uniprotkb:mpk1(gene name synonym)|uniprotkb:Myelin xP42 protein kinase(gene name synonym)|uniprotkb:Myelin basic protein kinase(gene name synonym)|uniprotkb:M phase MAP kinase(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Gavin et al. (1999)	pubmed:10074458|mint:MINT-5211221	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6957807|mint:MINT-15785	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR016239(Ribosomal protein S6 kinase II)|interpro:IPR017892|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR011009(Protein kinase-like)|refseq:NP_001085310.1|interpro:IPR041906|mint:MINT-364418(identity)	go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_001083548.1|interpro:IPR011009(Protein kinase-like)|mint:MINT-364423(identity)	-	function:Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of transcription|comment:mint|comment:"Stoichiometry: 1.0"	comment:mint|function:"Phosphorylates microtubule-associated protein 2 (MAP2). Myelin basic protein (MBP), and Elk-1; may promote entry in the cell cycle. Activated by M phase promoting factor (MPF)"|comment:"Stoichiometry: 1.0"	comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2001/03/30	2014/10/16	rogid:kmeawN9mJF+B514TVG+cmspnXCk8355	rogid:pVsO+47tJOR2yAYrvuLVW4sJoDg8355	intact-crc:16156FB8236260C3|rigid:nkkpqxKRjgOHDlOFZ96NAONhfU0	false	binding-associated region:709-733(MINT-364419)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)