Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4
The SMAD2/3:SMAD4 complex transfers to the nucleus
Phospho R-SMAD(SMAD2/3):CO-SMAD(SMAD4):FOXH1 Binds Activin Response Element
Cleavage of NODAL Proprotein
The NODAL Receptor Binds NODAL Ligands
Type II Activin Receptor (ActRII/ACVR2) Phosphorylates Type I Activin Receptor (ActRIB/ACVR1B) in Response to NODAL
Type II Activin Receptor (ActRIIB/ACVR2B) Phosphorylates Type I Activin Receptor (ActRIC/ACVR1C) in Response to NODAL
Phosphorylation of R-SMAD2/3 by NODAL Receptor
Phospho R-SMAD(SMAD2/3):CO-SMAD(SMAD4):FOXO3 Binds FoxO3a-binding Elements
CERBERUS Binds NODAL
LEFTY Binds NODAL
LEFTY Binds the EGF-CFC Coreceptor in the NODAL Receptor
Signaling by NODAL
Regulation of Signaling by NODAL