TEX4
label: TIM22
label: TIMM22
label: UniProt:Q9Y584 TIMM22

TOMM40 Complex Transports Proteins Across the Outer Mitochondrial Membrane
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005741
type: GO_0008320
BFO_0000050: Mitochondrial Protein Import
directly activates: MIA40:ERV1 (CHCHD4:GFER) Catalyzes Formation of Disulfide Bonds
directly activates: TIMM8:TIMM13 Chaperones Hydrophobic Proteins
directly activates: TIMM9:TIMM10 Binds Hydrophobic Proteins
directly activates: SAM50 Complex Inserts Proteins into Mitochondrial Outer Membrane
directly activates: TIMM22 Inserts Proteins into Inner Membrane
directly activates: Precursor Proteins Enter TIMM23 SORT
directly activates: Precursor Proteins Enter TIMM23 PAM
directly activates: Catalysis1566
directly activates: Catalysis1567
directly activates: Catalysis1568

MIA40:ERV1 (CHCHD4:GFER) Catalyzes Formation of Disulfide Bonds
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005758
type: GO_0015035
BFO_0000050: Mitochondrial Protein Import

TIMM8:TIMM13 Chaperones Hydrophobic Proteins
type: GO_0003674
BFO_0000050: Mitochondrial Protein Import
directly activates: SAM50 Complex Inserts Proteins into Mitochondrial Outer Membrane
directly activates: TIMM22 Inserts Proteins into Inner Membrane
directly activates: Catalysis1567
directly activates: Catalysis1568

TIMM9:TIMM10 Binds Hydrophobic Proteins
type: GO_0003674
BFO_0000050: Mitochondrial Protein Import
directly activates: TIMM9:TIMM10 Delivers Proteins to TIMM22

TIMM9:TIMM10 Delivers Proteins to TIMM22
type: GO_0003674
BFO_0000050: Mitochondrial Protein Import
directly activates: TIMM22 Inserts Proteins into Inner Membrane
directly activates: Catalysis1568

SAM50 Complex Inserts Proteins into Mitochondrial Outer Membrane
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005741
type: GO_0032977
BFO_0000050: Mitochondrial Protein Import

TIMM22 Inserts Proteins into Inner Membrane
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005743
type: Restriction
  on property: enabled by
  some values from: TEX4
type: GO_0032977
BFO_0000050: Mitochondrial Protein Import

Precursor Proteins Enter TIMM23 SORT
type: GO_0003674
BFO_0000050: Mitochondrial Protein Import
directly activates: MPP Cleaves Presequence of Inner Membrane Precursors
directly activates: Catalysis1569

MPP Cleaves Presequence of Inner Membrane Precursors
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005759
type: GO_0004222
BFO_0000050: Mitochondrial Protein Import
directly activates: TIMM23 SORT Inserts Proteins into Inner Membrane
directly activates: Catalysis1570

TIMM23 SORT Inserts Proteins into Inner Membrane
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005743
type: GO_0032977
BFO_0000050: Mitochondrial Protein Import

Precursor Proteins Enter TIMM23 PAM
type: GO_0003674
BFO_0000050: Mitochondrial Protein Import
directly activates: MPP Cleaves Presequence of Matrix Precursors
directly activates: Catalysis1571

MPP Cleaves Presequence of Matrix Precursors
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005759
type: GO_0004222
BFO_0000050: Mitochondrial Protein Import
directly activates: TIMM23 PAM Imports Proteins to Mitochondrial Matrix
directly activates: Catalysis1572

TIMM23 PAM Imports Proteins to Mitochondrial Matrix
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005743
type: GO_0008320
BFO_0000050: Mitochondrial Protein Import

Mitochondrial Protein Import
type: GO_0008150