CYP1A2
UniProt:P05177 CYP1A2
COMT
UniProt:P21964 COMT
NNMT
UniProt:P40261 NNMT
TPMT
UniProt:P51580 TPMT
MTR transfers CH3 group from MeCbl to HCYS
Methionine is reformed
SAM is sythesized from methionine's reaction with ATP
S-adenoylhomocysteine is hydrolyzed
S-atom dealkylation of 6-methylmercaptopurine
6-mercaptopurine can be S-methylated
2-mercaptoethanol can be S-methylated
Pyridine can be N-methylated
3,4-dihydroxybenzoate can be O-methylated
Methylation