Binding of REV1 to lesioned DNA template
Misinsertion of bases opposite to the lesion by HREV1
Elongation by REV1 protein
Binding of Pol eta to lesioned DNA template
Insertion of correct bases opposite to the lesion by Pol eta
Elongation by Pol eta
Binding of Pol zeta to lesioned DNA template
Formation of Pol zeta complex
Elongation by Pol zeta complex
DNA Damage Bypass
Translesion synthesis by DNA polymerases bypassing lesion on DNA template
Translesion synthesis by HREV1
Translesion synthesis by Pol eta
Translesion synthesis by Pol zeta