FYN
label: UniProt:P06241 FYN

Grb2 binds CD28
type: GO_0003674
BFO_0000050: CD28 dependent Vav1 pathway
directly activates: Translocation of Vav1 to CD28

Translocation of Vav1 to CD28
type: GO_0003674
BFO_0000050: CD28 dependent Vav1 pathway
directly activates: Activation of Vav1
directly activates: Catalysis254

Activation of Vav1
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: enabled by
  some values from: FYN
type: GO_0004713
BFO_0000050: CD28 dependent Vav1 pathway
directly activates: Activation of Rac1 by pVav1
directly activates: Activation of Cdc42 by pVav1
directly activates: Catalysis255
directly activates: Catalysis256

Activation of Rac1 by pVav1
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0005085
BFO_0000050: CD28 dependent Vav1 pathway
directly activates: Activation of PAK by Rac1 and Cdc42

Activation of Cdc42 by pVav1
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0005085
BFO_0000050: CD28 dependent Vav1 pathway
directly activates: Activation of PAK by Rac1 and Cdc42

Activation of PAK by Rac1 and Cdc42
type: GO_0003674
BFO_0000050: CD28 dependent Vav1 pathway

CD28 dependent Vav1 pathway
type: GO_0008150