phenylalanine + tetrahydrobiopterin + O2 => tyrosine + 4a-hydroxytetrahydrobiopterin + H2O
phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine
4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O
q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+
tyrosine + alpha-ketoglutarate <=> p-hydroxyphenylpyruvate + glutamate
p-hydroxyphenylpyruvate + glutamate <=> tyrosine + alpha-ketoglutarate
p-hydroxyphenylpyruvate + O2 => homogentisate + CO2
homogentisate + O2 => maleylacetoacetate
maleylacetoacetate => fumarylacetoacetate
fumarylacetoacetate => fumarate + acetoacetate
Phenylalanine and tyrosine catabolism