phenylalanine + tetrahydrobiopterin + O2 => tyrosine + 4a-hydroxytetrahydrobiopterin + H2O
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004505
BFO_0000050: Phenylalanine and tyrosine catabolism
directly activates: 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O
directly activates: tyrosine + alpha-ketoglutarate <=> p-hydroxyphenylpyruvate + glutamate
directly activates: Catalysis2870
directly activates: Catalysis2872

phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0047312
BFO_0000050: Phenylalanine and tyrosine catabolism

4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0008124
BFO_0000050: Phenylalanine and tyrosine catabolism
directly activates: q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+
directly activates: Catalysis2871

q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004155
BFO_0000050: Phenylalanine and tyrosine catabolism
directly activates: phenylalanine + tetrahydrobiopterin + O2 => tyrosine + 4a-hydroxytetrahydrobiopterin + H2O
directly activates: Catalysis1288
directly activates: Control221

tyrosine + alpha-ketoglutarate <=> p-hydroxyphenylpyruvate + glutamate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004838
BFO_0000050: Phenylalanine and tyrosine catabolism
directly activates: p-hydroxyphenylpyruvate + O2 => homogentisate + CO2
directly activates: Catalysis2874

p-hydroxyphenylpyruvate + glutamate <=> tyrosine + alpha-ketoglutarate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004838
BFO_0000050: Phenylalanine and tyrosine catabolism

p-hydroxyphenylpyruvate + O2 => homogentisate + CO2
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0003868
BFO_0000050: Phenylalanine and tyrosine catabolism
directly activates: homogentisate + O2 => maleylacetoacetate
directly activates: Catalysis2875

homogentisate + O2 => maleylacetoacetate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004411
BFO_0000050: Phenylalanine and tyrosine catabolism
directly activates: maleylacetoacetate => fumarylacetoacetate
directly activates: Catalysis2876

maleylacetoacetate => fumarylacetoacetate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0016034
BFO_0000050: Phenylalanine and tyrosine catabolism
directly activates: fumarylacetoacetate => fumarate + acetoacetate
directly activates: Catalysis2877

fumarylacetoacetate => fumarate + acetoacetate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004334
BFO_0000050: Phenylalanine and tyrosine catabolism

Phenylalanine and tyrosine catabolism
type: GO_0008150