SRC
label: SRC1
label: UniProt:P12931-1 SRC

PRKCQ
label: PRKCT
label: UniProt:Q04759 PRKCQ

DCC interaction with Netrin-1
type: GO_0003674
BFO_0000050: DCC mediated attractive signaling
directly activates: Netrin-1 induced DCC clustering

Netrin-1 induced DCC clustering
type: GO_0003674
BFO_0000050: DCC mediated attractive signaling
directly activates: FADK1 interaction with DCC

FADK1 interaction with DCC
type: GO_0003674
BFO_0000050: DCC mediated attractive signaling
directly activates: Phosphorylation of FADK1
directly activates: Catalysis3187

Phosphorylation of FADK1
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0004713
BFO_0000050: DCC mediated attractive signaling
directly activates: Recruitment of Src and Fyn to DCC:FADK1

Recruitment of Src and Fyn to DCC:FADK1
type: GO_0003674
BFO_0000050: DCC mediated attractive signaling
directly activates: Phosphorylation of DCC by Fyn
directly activates: Catalysis3188

Phosphorylation of DCC by Fyn
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0004713
BFO_0000050: DCC mediated attractive signaling
directly activates: DCC interacting NCK-1

DCC interacting NCK-1
type: GO_0003674
BFO_0000050: DCC mediated attractive signaling
directly activates: RhoGTPase GEF's recruited to DCC

RhoGTPase GEF's recruited to DCC
type: GO_0003674
BFO_0000050: DCC mediated attractive signaling
directly activates: Activation of Cdc42
directly activates: Activation of Rac1
directly activates: Catalysis3189
directly activates: Catalysis3190

Activation of Cdc42
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0005089
BFO_0000050: DCC mediated attractive signaling
directly activates: Recruitment and activation of N-WASP by Cdc42
directly activates: BiochemicalReaction691

Activation of Rac1
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0005089
BFO_0000050: DCC mediated attractive signaling
directly activates: Recruitment of ABLIM to the plasma membrane
directly activates: BiochemicalReaction691

Recruitment and activation of N-WASP by Cdc42
type: GO_0003674
BFO_0000050: DCC mediated attractive signaling

Recruitment of ABLIM to the plasma membrane
type: GO_0003674
BFO_0000050: DCC mediated attractive signaling

UNC-5 binds Netrin-1
type: GO_0003674
BFO_0000050: Netrin mediated repulsion signals
directly activates: DCC heterodimerizes with UNC-5:Netrin-1

DCC heterodimerizes with UNC-5:Netrin-1
type: GO_0003674
BFO_0000050: Netrin mediated repulsion signals

Phosphorylation of Unc5C
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: enabled by
  some values from: SRC
type: Restriction
  on property: enabled by
  some values from: SRC
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004713
BFO_0000050: Netrin mediated repulsion signals
directly activates: Shp2 binds pUnc5C

Shp2 binds pUnc5C
type: GO_0003674
BFO_0000050: Netrin mediated repulsion signals

DCC interaction with ROBO-1
type: GO_0003674
BFO_0000050: Netrin-1 signaling

DCC interaction with SIAH1
type: GO_0003674
BFO_0000050: Netrin-1 signaling

DCC interaction with SIAH2
type: GO_0003674
BFO_0000050: Netrin-1 signaling

Translocation of Ezrin to plasma membrane
type: GO_0003674
BFO_0000050: Netrin-1 signaling
directly activates: Phosphorylation and activation of Ezrin
directly activates: Catalysis3192

Phosphorylation and activation of Ezrin
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: enabled by
  some values from: PRKCQ
type: GO_0004672
BFO_0000050: Netrin-1 signaling
directly activates: DCC interaction with Ezrin

DCC interaction with Ezrin
type: GO_0003674
BFO_0000050: Netrin-1 signaling

Netrin-4 binds DCC/UNC5A
type: GO_0003674
BFO_0000050: Netrin-1 signaling

Neogenin binds Netrin-1
type: GO_0003674
BFO_0000050: Netrin-1 signaling

Neogenin binds repulsive guidance molecules (RGDs)
type: GO_0003674
BFO_0000050: Netrin-1 signaling

Myosin-X binds DCC/Neogenin
type: GO_0003674
BFO_0000050: Netrin-1 signaling

PIKE-L interaction with UNC5B
type: GO_0003674
BFO_0000050: Netrin-1 signaling

PITPalpha binds DCC
type: GO_0003674
BFO_0000050: Role of second messengers in netrin-1 signaling

Phosphorylation of PLCgamma by Netrin-1
type: GO_0003674
BFO_0000050: Role of second messengers in netrin-1 signaling

PIP2 hydrolysis
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0004435
BFO_0000050: Role of second messengers in netrin-1 signaling

Activation of TRPC channels by Netrin-1
type: GO_0003674
BFO_0000050: Role of second messengers in netrin-1 signaling

Netrin-1 signaling
type: GO_0008150

DCC mediated attractive signaling
type: GO_0008150
BFO_0000050: Netrin-1 signaling

Netrin mediated repulsion signals
type: GO_0008150
BFO_0000050: Netrin-1 signaling

Role of second messengers in netrin-1 signaling
type: GO_0008150
BFO_0000050: Netrin-1 signaling