NICD1 displaces co-repressor complex from RBPJ (CSL)
NICD1 in complex with RBPJ (CSL) recruits MAML
HES1 binds TLE
MAML in complex with NICD1 recruits CDK8
NICD1 is phosphorylated by CDK8
Phosphorylated NICD1 binds FBXW7
Ubiquitination of NICD1 by FBWX7
NICD1 binds HIF1A
NOTCH1 Intracellular Domain Regulates Transcription
NOTCH1 stimulates HES1 transcription
NOTCH1 stimulates MYC transcription
NOTCH1 stimulates HES5 transcription
NOTCH1 stimulates HEY transcription