NICD1 displaces co-repressor complex from RBPJ (CSL)
type: GO_0003674
BFO_0000050: NOTCH1 Intracellular Domain Regulates Transcription
directly activates: NICD1 in complex with RBPJ (CSL) recruits MAML

NICD1 in complex with RBPJ (CSL) recruits MAML
type: GO_0003674
BFO_0000050: NOTCH1 Intracellular Domain Regulates Transcription
directly activates: MAML in complex with NICD1 recruits CDK8
directly activates: NOTCH1 stimulates HES1 transcription
directly activates: NOTCH1 stimulates MYC transcription
directly activates: NOTCH1 stimulates HES5 transcription
directly activates: NOTCH1 stimulates HEY transcription
directly activates: TemplateReactionRegulation51
directly activates: TemplateReactionRegulation52
directly activates: TemplateReactionRegulation53
directly activates: TemplateReactionRegulation54

HES1 binds TLE
type: GO_0003674
BFO_0000050: NOTCH1 Intracellular Domain Regulates Transcription

MAML in complex with NICD1 recruits CDK8
type: GO_0003674
BFO_0000050: NOTCH1 Intracellular Domain Regulates Transcription
directly activates: NICD1 is phosphorylated by CDK8
directly activates: Catalysis1426

NICD1 is phosphorylated by CDK8
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005654
type: GO_0004693
BFO_0000050: NOTCH1 Intracellular Domain Regulates Transcription
directly activates: Phosphorylated NICD1 binds FBXW7

Phosphorylated NICD1 binds FBXW7
type: GO_0003674
BFO_0000050: NOTCH1 Intracellular Domain Regulates Transcription
directly activates: Ubiquitination of NICD1 by FBWX7
directly activates: Catalysis1427

Ubiquitination of NICD1 by FBWX7
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005654
type: GO_0004842
BFO_0000050: NOTCH1 Intracellular Domain Regulates Transcription

NICD1 binds HIF1A
type: GO_0003674
BFO_0000050: NOTCH1 Intracellular Domain Regulates Transcription

NOTCH1 Intracellular Domain Regulates Transcription
type: GO_0008150

NOTCH1 stimulates HES1 transcription
type: GO_0003674
BFO_0000050: NOTCH1 Intracellular Domain Regulates Transcription
directly activates: HES1 binds TLE

NOTCH1 stimulates MYC transcription
type: GO_0003674
BFO_0000050: NOTCH1 Intracellular Domain Regulates Transcription
directly activates: TemplateReaction33
directly activates: TemplateReactionRegulation49

NOTCH1 stimulates HES5 transcription
type: GO_0003674
BFO_0000050: NOTCH1 Intracellular Domain Regulates Transcription

NOTCH1 stimulates HEY transcription
type: GO_0003674
BFO_0000050: NOTCH1 Intracellular Domain Regulates Transcription