GILT
IFI30
IP30
UniProt:P13284 IFI30
LGMN
PRSC1
UniProt:Q99538 LGMN
Formation of MHC II alpha beta heterodimer
Interaction of invariant chain trimer and MHC II alpha beta dimer
Formation of nonameric complex
Formation of COPII vesicle
Fusion of COPII vesicle with Golgi complex
Translocation of MHC II:Ii complex to TGN
Transport of MHC II:Ii complex along Golgi to TGN
TGN-lysosomal vesicle coat assembly
Translocation of TGN-lysosome vesicle to lysosome
TGN-lysosome vesicle uncoating and release of nonameric complex to lysosome
Transport of MHC II:Ii complex to plasma membrane
Insertion of MHC II:Ii complex in to the plasma membrane
Recruitment of clathrin coated vesicle by Ii
Internalization of MHC II:Ii clathrin coated vesicle
Uncoating of clathrin-coated vesicles and fusion with endosomes
Trafficking of nonameric complex in the endocytic pathway
Initial proteolyis of Ii by aspartic proteases to lip22
Cleavage of lip22 to lip10
Generation of CLIP from lip10
Disassociation of CLIP from MHC II
MHC class II antigen internalization
Reduction of disulphide bonds in MHC II antigens
MHC class II antigen processing
Loading of antigenic peptides
Transport of antigen loaded MHC II molecules to surface
MHC class II antigen presentation