Glucose 6-phosphate is isomerized to form fructose-6-phosphate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004347
BFO_0000050: Glycolysis
directly activates: D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP
directly activates: D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP
directly activates: BiochemicalReaction4602
directly activates: BiochemicalReaction4604
directly activates: Catalysis1956
directly activates: Catalysis1957
directly activates: Catalysis2015
directly activates: Catalysis2017
directly activates: Control357
directly activates: Control358
directly activates: Control359
directly activates: Control360
directly activates: Control361
directly activates: Control362
label: alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate

Dephosphorylation of phosphoPFKFB1 by PP2A complex
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0008195
BFO_0000050: Glycolysis
directly activates: D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP
directly activates: Catalysis1956
directly activates: Control357

D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0003873
BFO_0000050: Glycolysis
label: Fructose 6-phosphate and ATP react to form fructose 2,6-bisphosphate and ADP

D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0003872
BFO_0000050: Glycolysis
directly activates: D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate
directly activates: Catalysis1958

D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004332
BFO_0000050: Glycolysis
directly activates: dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate
directly activates: Catalysis1959

dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004807
BFO_0000050: Glycolysis
directly activates: D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+
directly activates: BiochemicalReaction4600
directly activates: BiochemicalReaction4604
directly activates: Catalysis1960
directly activates: Catalysis2013
directly activates: Catalysis2017

D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004365
BFO_0000050: Glycolysis
directly activates: 1,3-Bisphosphoglycerate and ADP react to form 3-phosphoglycerate and ATP
directly activates: BiochemicalReaction4587
directly activates: Catalysis1961
directly activates: Catalysis2000
label: Glyceraldehyde 3 phosphate, NAD+, and orthophosphate react to form 1,3 bisphosphoglycerate and NADH + H+

1,3-Bisphosphoglycerate and ADP react to form 3-phosphoglycerate and ATP
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004618
BFO_0000050: Glycolysis
directly activates: 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate
directly activates: Catalysis1962
label: 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ADP

3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004619
BFO_0000050: Glycolysis
directly activates: 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O
directly activates: Catalysis1963

2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004634
BFO_0000050: Glycolysis
directly activates: phosphoenolpyruvate + ADP => pyruvate + ATP
directly activates: Catalysis1964
directly activates: Control363
directly activates: Control364
directly activates: Control365
directly activates: Control366

phosphoenolpyruvate + ADP => pyruvate + ATP
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004743
BFO_0000050: Glycolysis
directly activates: BiochemicalReaction5399
directly activates: BiochemicalReaction5403
directly activates: Catalysis2595
directly activates: Catalysis2599

Glycolysis
type: GO_0008150