G alpha (s) activates adenylate cyclase
type: GO_0003674
BFO_0000050: G alpha (s) signalling events
directly activates: BiochemicalReaction1771
directly activates: Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate
directly activates: Catalysis1878
directly activates: Catalysis747
directly activates: Control340
directly activates: Control341
directly activates: Control342

Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs
type: GO_0003674
BFO_0000050: G alpha (s) signalling events
directly activates: Liganded Gs-activating GPCR acts as a GEF for Gs
directly activates: Catalysis1877

Liganded Gs-activating GPCR acts as a GEF for Gs
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0005085
BFO_0000050: G alpha (s) signalling events
directly activates: The Ligand:GPCR:Gs complex dissociates
directly activates: BiochemicalReaction4384
directly activates: BiochemicalReaction4386

The Ligand:GPCR:Gs complex dissociates
type: GO_0003674
BFO_0000050: G alpha (s) signalling events
directly activates: G alpha (s) activates adenylate cyclase
directly activates: G alpha (s) auto-inactivates by hydrolysing GTP to GDP
directly activates: Catalysis1880

Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0004016
BFO_0000050: G alpha (s) signalling events
directly activates: cAMP degradation by Phosphodiesterases
directly activates: Catalysis1879

cAMP degradation by Phosphodiesterases
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004115
BFO_0000050: G alpha (s) signalling events

G alpha (s) auto-inactivates by hydrolysing GTP to GDP
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0003924
BFO_0000050: G alpha (s) signalling events
directly activates: Inactive G alpha (s) reassociates with G beta:gamma

Inactive G alpha (s) reassociates with G beta:gamma
type: GO_0003674
BFO_0000050: G alpha (s) signalling events

G alpha (s) signalling events
type: GO_0008150