Recruitment of TEC kinases to p-SLP-76
type: GO_0003674
BFO_0000050: FCERI mediated Ca+2 mobilization
directly activates: Phosphorylation of TEC kinases by p-SYK
directly activates: Catalysis472

Phosphorylation of TEC kinases by p-SYK
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0004713
BFO_0000050: FCERI mediated Ca+2 mobilization
directly activates: Autophosphorylation of BTK/ITK
directly activates: Catalysis473

Autophosphorylation of BTK/ITK
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0004713
BFO_0000050: FCERI mediated Ca+2 mobilization
directly activates: Phosphorylation of PLC-gamma
directly activates: Catalysis474

Phosphorylation of PLC-gamma
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0004713
BFO_0000050: FCERI mediated Ca+2 mobilization

Hydrolysis of PIP2 by PLCG
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0004435
BFO_0000050: FCERI mediated Ca+2 mobilization
directly activates: BiochemicalReaction1327
directly activates: BiochemicalReaction1328

Activation of Calcineurin
type: GO_0003674
BFO_0000050: FCERI mediated Ca+2 mobilization
directly activates: Calcineurin binds and dephosphorylates NFAT
directly activates: Catalysis476

Calcineurin binds and dephosphorylates NFAT
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0033192
BFO_0000050: FCERI mediated Ca+2 mobilization
directly activates: Translocation of CaN:CaM:NFAT to nucleus

Translocation of CaN:CaM:NFAT to nucleus
type: GO_0003674
BFO_0000050: FCERI mediated Ca+2 mobilization

Calcium binds calmodulin
type: GO_0003674
BFO_0000050: FCERI mediated Ca+2 mobilization
directly activates: BiochemicalReaction1287
directly activates: BiochemicalReaction1292
directly activates: BiochemicalReaction1296
directly activates: BiochemicalReaction1298
directly activates: Activation of Calcineurin
directly activates: BiochemicalReaction243
directly activates: BiochemicalReaction4415
directly activates: BiochemicalReaction5368
directly activates: Catalysis453
directly activates: Control94
directly activates: Control95
directly activates: Modulation7
directly activates: Modulation8
directly activates: Pathway336

IP3 binds to the IP3 receptor, opening the endoplasmic reticulum Ca2+ channel
type: GO_0003674
BFO_0000050: FCERI mediated Ca+2 mobilization
directly activates: Release of calcium from intracellular stores by IP3 receptor activation
directly activates: Catalysis272
directly activates: Control50

Release of calcium from intracellular stores by IP3 receptor activation
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0005261
BFO_0000050: FCERI mediated Ca+2 mobilization
directly activates: Calcium binds calmodulin
directly activates: BiochemicalReaction5350
directly activates: BiochemicalReaction717
directly activates: BiochemicalReaction722
directly activates: Catalysis2575
directly activates: Catalysis273
directly activates: Control428
directly activates: Control429
directly activates: Control430
directly activates: Control431
directly activates: Pathway1104

FCERI mediated Ca+2 mobilization
type: GO_0008150