Cytochrome C Binds to Apaf-1
Cytochrome C:Apaf-1 binds Procaspase-9
Cleavage of Procaspase-9 to Caspase-9
Cleavage of Procaspase-3 by the apoptosome
Cleavage of Procaspase-7 by the apoptosome
Cytochrome c-mediated apoptotic response
Formation of apoptosome
Activation of caspases through apoptosome-mediated cleavage