Cytochrome C Binds to Apaf-1
type: GO_0003674
BFO_0000050: Formation of apoptosome

Cytochrome C:Apaf-1 binds Procaspase-9
type: GO_0003674
BFO_0000050: Formation of apoptosome
directly activates: Cleavage of Procaspase-9 to Caspase-9
directly activates: Catalysis3113

Cleavage of Procaspase-9 to Caspase-9
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004197
BFO_0000050: Formation of apoptosome

Cleavage of Procaspase-3 by the apoptosome
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004197
BFO_0000050: Activation of caspases through apoptosome-mediated cleavage
directly activates: BiochemicalReaction6037
directly activates: BiochemicalReaction6038
directly activates: BiochemicalReaction6039
directly activates: BiochemicalReaction6040
directly activates: BiochemicalReaction6041
directly activates: BiochemicalReaction6044
directly activates: BiochemicalReaction6046
directly activates: BiochemicalReaction6047
directly activates: BiochemicalReaction6048
directly activates: BiochemicalReaction6049
directly activates: BiochemicalReaction6050
directly activates: BiochemicalReaction6051
directly activates: BiochemicalReaction6059
directly activates: BiochemicalReaction6060
directly activates: BiochemicalReaction6066
directly activates: BiochemicalReaction6068
directly activates: BiochemicalReaction6069
directly activates: BiochemicalReaction6084
directly activates: Catalysis3116
directly activates: Catalysis3117
directly activates: Catalysis3118
directly activates: Catalysis3119
directly activates: Catalysis3120
directly activates: Catalysis3123
directly activates: Catalysis3125
directly activates: Catalysis3126
directly activates: Catalysis3127
directly activates: Catalysis3128
directly activates: Catalysis3129
directly activates: Catalysis3130
directly activates: Catalysis3138
directly activates: Catalysis3139
directly activates: Catalysis3145
directly activates: Catalysis3147
directly activates: Catalysis3148
directly activates: Catalysis3155

Cleavage of Procaspase-7 by the apoptosome
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004197
BFO_0000050: Activation of caspases through apoptosome-mediated cleavage
directly activates: BiochemicalReaction6039
directly activates: BiochemicalReaction6041
directly activates: BiochemicalReaction6061
directly activates: BiochemicalReaction6071
directly activates: Catalysis3118
directly activates: Catalysis3120
directly activates: Catalysis3140
directly activates: Catalysis3150

Cytochrome c-mediated apoptotic response
type: GO_0008150

Formation of apoptosome
type: GO_0008150
BFO_0000050: Cytochrome c-mediated apoptotic response

Activation of caspases through apoptosome-mediated cleavage
type: GO_0008150
BFO_0000050: Cytochrome c-mediated apoptotic response