PDI is a chaperone for collagen peptides
type: GO_0003674
BFO_0000050: Collagen biosynthesis and modifying enzymes

Collagen prolyl 4-hydroxylase converts proline to 4-hydroxyproline
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: GO_0004656
BFO_0000050: Collagen biosynthesis and modifying enzymes

Collagen prolyl 3-hydroxylase converts proline to 3-hydroxyproline
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: GO_0019797
BFO_0000050: Collagen biosynthesis and modifying enzymes

Procollagen lysyl hydrolases convert lysine to 5-hydroxylysine
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0008475
BFO_0000050: Collagen biosynthesis and modifying enzymes
directly activates: Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2.
directly activates: Galactosylation of collagen propeptide hydroxylysines by PLOD3
directly activates: Catalysis931
directly activates: Catalysis932

Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2.
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: GO_0050211
BFO_0000050: Collagen biosynthesis and modifying enzymes
directly activates: Glucosylation of collagen propeptide hydroxylysines
directly activates: Catalysis933

Galactosylation of collagen propeptide hydroxylysines by PLOD3
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0050211
BFO_0000050: Collagen biosynthesis and modifying enzymes
directly activates: Glucosylation of collagen propeptide hydroxylysines
directly activates: Catalysis933

Glucosylation of collagen propeptide hydroxylysines
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0033823
BFO_0000050: Collagen biosynthesis and modifying enzymes

Association of procollagen chains
type: GO_0003674
BFO_0000050: Collagen biosynthesis and modifying enzymes

Procollagen triple helix formation
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: GO_0003755
BFO_0000050: Collagen biosynthesis and modifying enzymes

Dimerization of procollagen type VI
type: GO_0003674
BFO_0000050: Collagen biosynthesis and modifying enzymes
directly activates: Tetramerization of procollagen VI

Tetramerization of procollagen VI
type: GO_0003674
BFO_0000050: Collagen biosynthesis and modifying enzymes

Secretion of collagens
type: GO_0003674
BFO_0000050: Collagen biosynthesis and modifying enzymes

Secretion of transmembrane collagens
type: GO_0003674
BFO_0000050: Collagen biosynthesis and modifying enzymes

Removal of fibrillar collagen N-propeptides
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005576
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005576
type: GO_0004222
BFO_0000050: Collagen biosynthesis and modifying enzymes
directly activates: Removal of fibrillar collagen C-propeptides
directly activates: Catalysis936
directly activates: Control151

Removal of fibrillar collagen C-propeptides
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005576
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005576
type: GO_0004222
BFO_0000050: Collagen biosynthesis and modifying enzymes

Formation of collagen fibrils
type: GO_0003674
BFO_0000050: Assembly of collagen fibrils and other multimeric structures
directly activates: Formation of collagen fibres

Formation of collagen networks
type: GO_0003674
BFO_0000050: Assembly of collagen fibrils and other multimeric structures

Collagen type VII dimerization
type: GO_0003674
BFO_0000050: Anchoring fibril formation
directly activates: Cleavage of collagen VII NC2 region by BMP1
directly activates: Catalysis937

Cleavage of collagen VII NC2 region by BMP1
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005576
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005576
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005576
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005576
type: GO_0004252
BFO_0000050: Anchoring fibril formation
directly activates: Formation of anchoring fibrils

Formation of anchoring fibrils
type: GO_0003674
BFO_0000050: Anchoring fibril formation
directly activates: Collagen type VII binds laminin-322 and collagen IV

Collagen type VII binds laminin-322 and collagen IV
type: GO_0003674
BFO_0000050: Anchoring fibril formation

Prolysyl oxidase activation
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005576
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005576
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005576
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005576
type: GO_0004222
BFO_0000050: Crosslinking of collagen fibrils
directly activates: Formation of allysine by LOX
directly activates: Formation of hydroxyallysine by LOX
directly activates: Catalysis939
directly activates: Catalysis940

Formation of allysine by LOX
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005576
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005576
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005576
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005576
type: GO_0004720
BFO_0000050: Crosslinking of collagen fibrils
directly activates: Formation of dehydro-lysinonorleucine cross-links
directly activates: Formation of dehydro-hydroxylysino-norleucine cross-links
directly activates: Crosslinking of collagen fibrils

Formation of hydroxyallysine by LOX
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005576
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005576
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005576
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005576
type: GO_0004720
BFO_0000050: Crosslinking of collagen fibrils
directly activates: Formation of lysino-5-ketonorleucine cross-links
directly activates: Formation of hydroxylysino-5-ketonorleucine cross-links

Formation of dehydro-lysinonorleucine cross-links
type: GO_0003674
BFO_0000050: Crosslinking of collagen fibrils

Formation of dehydro-hydroxylysino-norleucine cross-links
type: GO_0003674
BFO_0000050: Crosslinking of collagen fibrils
directly activates: Formation of histidino-hydroxylysinonorleucine cross-links

Formation of lysino-5-ketonorleucine cross-links
type: GO_0003674
BFO_0000050: Crosslinking of collagen fibrils
directly activates: Formation of lysyl-pyridinoline cross-links
directly activates: Formation of lysyl-pyrrole cross-links

Formation of hydroxylysino-5-ketonorleucine cross-links
type: GO_0003674
BFO_0000050: Crosslinking of collagen fibrils
directly activates: Formation of hydroxylysyl-pyridinoline cross-links
directly activates: Formation of hydroxylysyl-pyrrole cross-links

Formation of lysyl-pyridinoline cross-links
type: GO_0003674
BFO_0000050: Crosslinking of collagen fibrils

Formation of hydroxylysyl-pyridinoline cross-links
type: GO_0003674
BFO_0000050: Crosslinking of collagen fibrils

Formation of lysyl-pyrrole cross-links
type: GO_0003674
BFO_0000050: Crosslinking of collagen fibrils

Formation of hydroxylysyl-pyrrole cross-links
type: GO_0003674
BFO_0000050: Crosslinking of collagen fibrils

Formation of histidino-hydroxylysinonorleucine cross-links
type: GO_0003674
BFO_0000050: Crosslinking of collagen fibrils

Formation of collagen fibres
type: GO_0003674
BFO_0000050: Assembly of collagen fibrils and other multimeric structures

Collagen XI cross-links with collagen II
type: GO_0003674
BFO_0000050: Assembly of collagen fibrils and other multimeric structures

Collagen IX is cross-linked to the surface of collagen type II fibrils
type: GO_0003674
BFO_0000050: Assembly of collagen fibrils and other multimeric structures

Type XII and XIV collagens associate with type I and type II fibrils.
type: GO_0003674
BFO_0000050: Assembly of collagen fibrils and other multimeric structures

Type X collagen associates with collagen type II fibrils
type: GO_0003674
BFO_0000050: Assembly of collagen fibrils and other multimeric structures

Hemidesmosome formation
type: GO_0003674
BFO_0000050: Assembly of collagen fibrils and other multimeric structures

Release of endostatin-like peptides
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005576
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005576
type: GO_0004175
BFO_0000050: Assembly of collagen fibrils and other multimeric structures

Collagen formation
type: GO_0008150

Collagen biosynthesis and modifying enzymes
type: GO_0008150
BFO_0000050: Collagen formation

Assembly of collagen fibrils and other multimeric structures
type: GO_0008150
BFO_0000050: Collagen formation

Anchoring fibril formation
type: GO_0008150
BFO_0000050: Assembly of collagen fibrils and other multimeric structures

Crosslinking of collagen fibrils
type: GO_0008150
BFO_0000050: Assembly of collagen fibrils and other multimeric structures