PDI is a chaperone for collagen peptides
Collagen prolyl 4-hydroxylase converts proline to 4-hydroxyproline
Collagen prolyl 3-hydroxylase converts proline to 3-hydroxyproline
Procollagen lysyl hydrolases convert lysine to 5-hydroxylysine
Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2.
Galactosylation of collagen propeptide hydroxylysines by PLOD3
Glucosylation of collagen propeptide hydroxylysines
Association of procollagen chains
Procollagen triple helix formation
Dimerization of procollagen type VI
Tetramerization of procollagen VI
Secretion of collagens
Secretion of transmembrane collagens
Removal of fibrillar collagen N-propeptides
Removal of fibrillar collagen C-propeptides
Formation of collagen fibrils
Formation of collagen networks
Collagen type VII dimerization
Cleavage of collagen VII NC2 region by BMP1
Formation of anchoring fibrils
Collagen type VII binds laminin-322 and collagen IV
Prolysyl oxidase activation
Formation of allysine by LOX
Formation of hydroxyallysine by LOX
Formation of dehydro-lysinonorleucine cross-links
Formation of dehydro-hydroxylysino-norleucine cross-links
Formation of lysino-5-ketonorleucine cross-links
Formation of hydroxylysino-5-ketonorleucine cross-links
Formation of lysyl-pyridinoline cross-links
Formation of hydroxylysyl-pyridinoline cross-links
Formation of lysyl-pyrrole cross-links
Formation of hydroxylysyl-pyrrole cross-links
Formation of histidino-hydroxylysinonorleucine cross-links
Formation of collagen fibres
Collagen XI cross-links with collagen II
Collagen IX is cross-linked to the surface of collagen type II fibrils
Type XII and XIV collagens associate with type I and type II fibrils.
Type X collagen associates with collagen type II fibrils
Hemidesmosome formation
Release of endostatin-like peptides
Collagen formation
Collagen biosynthesis and modifying enzymes
Assembly of collagen fibrils and other multimeric structures
Anchoring fibril formation
Crosslinking of collagen fibrils