*reference: PMID:21283692 *table: tableS1 *description: Top 30 up and top 30 down regulated genes in AD total brain. *original_results: Protein localization is the most enriched cluster across all three regions, while vesicle mediated transport and phosphate metabolic processes are within the top five clusters and proteolysis and regulation of GTPase activity are within the top seven for all three tissue samples. The only brain-specific cluster present in the top ten across all three samples is neuronal development. This level of functional overlap between the samples is to be expected given that they all originate from the same tissue *original_tool: DAVID *reference_set: 9606 *expected_enriched_term: *item_id_type: symbol ### IGHA1 RP11-552E20.3 PCYT1A SLC7A9 RAD54L OAS1 MTIF2 STAB1 CD22 AC018730.1 RBM6 ANKRD18A XAF1 PLOD3 LY6H IFI35 IFI44L P4HA2 TPR MMP17 MRPS5 EIF6 BST2 KIAA1522 RASAL1 CUL9 MED13L LASS4 ZMAT5 NOL8 PTCH1 ODZ1 REV3L TBC1D16 UBE4A WDFY3 MYO9A PPM1H PIP5K3 SCN2A2 MGAT5 ARFGEF2 INPP5A EBF1 NBEA CNOT1 WDR7 MON2 CADPS TNC ITGB8 MED13L KIAA0802 ABLIM1 DAO TFRC GRM1 GRM4 RELN ANK1 RELN "Differential gene expression for total brain was calculated using the ratio of AD versus normal FPKM values for every gene identified as expressed by Cufflinks. The genes were ranked on this ratio (fold change), and those with the 30 highest and 30 lowest fold change values are shown here."