'Protein_Id'	'sf_name'	'definition'	'organism'	'gene_id'	'gene_symbol'	'Molecular function'	'Biological process'	'Cellular component'	'Protein class'	'Public_node_id'
'AN0'	'SUBFAMILY NOT NAMED'	''	''	''	''	'GO:0008168=methyltransferase activity;GO:0016740=transferase activity;GO:0003824=catalytic activity'	'GO:0009058=biosynthetic process;GO:0008152=metabolic process;GO:0006464=cellular protein modification process;GO:0019538=protein metabolic process;GO:0044238=primary metabolic process;GO:0009987=cellular process'	''	''	'PTN000853882'
'SULSO|EnsemblGenome=SSO2296|UniProtKB=Q97WD1'	''	'Cobalamin biosynthesis precorrin-6B methylase, putative (CbiE)'	'Sulfolobus solfataricus'	'EnsemblGenome:SSO2296'	'cbiE'	''	''	''	''	'PTN000094343'
'METJA|EnsemblGenome=MJ_1522|UniProtKB=Q58917'	''	'Probable cobalt-precorrin-7 C(5)-methyltransferase'	'Methanocaldococcus jannaschii'	'EnsemblGenome:MJ_1522'	'cbiE'	''	''	''	''	'PTN002248192'
'SALTY|EnsemblGenome=STM2031|UniProtKB=P0A2H1'	''	'Cobalt-precorrin-7 C(5)-methyltransferase'	'Salmonella typhimurium'	'EnsemblGenome:STM2031'	'cbiE'	''	''	''	''	'PTN002248194'
'LISMO|Gene=CAC99273|UniProtKB=Q8Y7S6'	''	'CbiE protein'	'Listeria monocytogenes'	'Gene:CAC99273'	'cbiE'	''	''	''	''	'PTN001843793'
'PYRAE|EnsemblGenome=PAE0340|UniProtKB=Q8ZZB5'	''	'Cobalamin biosynthesis precorrin-6Y methylase (CbiE)'	'Pyrobaculum aerophilum'	'EnsemblGenome:PAE0340'	'PAE0340'	''	''	''	''	'PTN000853935'
'FUSNN|EnsemblGenome=FN0966|UniProtKB=Q8REW9'	''	'Precorrin-6Y C5,15-methyltransferase (Decarboxylating)'	'Fusobacterium nucleatum'	'EnsemblGenome:FN0966'	'FN0966'	''	''	''	''	'PTN001464909'
'HALSA|EnsemblGenome=VNG_1568G|UniProtKB=Q9HPM0'	''	'Precorrin-3 methylase'	'Halobacterium salinarum'	'EnsemblGenome:VNG_1568G'	'cbiJ'	''	''	''	''	'PTN001329534'
'AN2'	'DIPHTHINE METHYL ESTER SYNTHASE'	''	''	''	''	'GO:0008168=methyltransferase activity;GO:0016740=transferase activity;GO:0003824=catalytic activity'	'GO:0009058=biosynthetic process;GO:0008152=metabolic process;GO:0006464=cellular protein modification process;GO:0019538=protein metabolic process;GO:0044238=primary metabolic process;GO:0009987=cellular process'	''	'PC00155=methyltransferase;PC00220=transferase'	'PTN000094270'
'DICPU|Gene=DICPUDRAFT_37635|UniProtKB=F0ZT50'	''	'Putative uncharacterized protein'	'Dictyostelium purpureum'	'Gene:DICPUDRAFT_37635'	'DICPUDRAFT_37635'	''	''	''	''	'PTN000853915'
'TETTS|EnsemblGenome=TTHERM_00833850|UniProtKB=Q23A33'	''	'Diphthine synthase'	'Tetrahymena thermophila'	'EnsemblGenome:TTHERM_00833850'	'TTHERM_00833850'	''	''	''	''	'PTN000094330'
'PUCGT|EnsemblGenome=PGTG_12290|UniProtKB=E3KPU9'	''	'Diphthine synthase'	'Puccinia graminis'	'EnsemblGenome:PGTG_12290'	'PGTG_12290'	''	''	''	''	'PTN000853912'
'HORSE|Ensembl=ENSECAG00000011656|UniProtKB=F7AIU7'	''	'Uncharacterized protein'	'Equus caballus'	'Ensembl:ENSECAG00000011656'	'DPH5'	''	''	''	''	'PTN001329524'
'EMENI|EnsemblGenome=CADANIAG00001948|UniProtKB=Q5BFG0'	''	'Diphthine methyl ester synthase'	'Emericella nidulans'	'EnsemblGenome:CADANIAG00001948'	'dph5'	''	''	''	''	'PTN000094322'
'NEMVE|EnsemblGenome=NEMVEDRAFT_v1g93189|UniProtKB=A7RTU2'	''	'Predicted protein'	'Nematostella vectensis'	'EnsemblGenome:NEMVEDRAFT_v1g93189'	'v1g93189'	''	''	''	''	'PTN000853895'
'GIAIC|EnsemblGenome=GL50803_28666|UniProtKB=A8BBU1'	''	'Diphthine synthase'	'Giardia intestinalis'	'EnsemblGenome:GL50803_28666'	'GL50803_28666'	''	''	''	''	'PTN000853924'
'BOVIN|Ensembl=ENSBTAG00000019029|UniProtKB=Q5E982'	''	'Diphthine methyl ester synthase'	'Bos taurus'	'Ensembl:ENSBTAG00000019029'	'DPH5'	''	''	''	''	'PTN000094293'
'CANFA|Ensembl=ENSCAFG00000019995|UniProtKB=E2RQL8'	''	'Uncharacterized protein'	'Canis familiaris'	'Ensembl:ENSCAFG00000019995'	'DPH5'	''	''	''	''	'PTN000094294'
'ENTHI|EnsemblGenome=EHI_127240|UniProtKB=C4LWZ7'	''	'Diphthine synthase, putative'	'Entamoeba histolytica'	'EnsemblGenome:EHI_127240'	'EHI_127240'	''	''	''	''	'PTN000094326'
'CANAL|Gene=CaO19.6682|UniProtKB=Q59NX3'	''	'Potential diphthamide methyltransferase'	'Candida albicans'	'Gene:CaO19.6682'	'DPH52'	''	''	''	''	'PTN001329530'
'ANOCA|Ensembl=ENSACAG00000003102|UniProtKB=G1KBI4'	''	'Uncharacterized protein'	'Anolis carolinensis'	'Ensembl:ENSACAG00000003102'	'DPH5'	''	''	''	''	'PTN001329527'
'PYRAE|EnsemblGenome=PAE1139|UniProtKB=Q8ZXR9'	''	'Diphthine synthase'	'Pyrobaculum aerophilum'	'EnsemblGenome:PAE1139'	'dphB'	''	''	''	''	'PTN000853928'
'PHYIT|EnsemblGenome=PITG_11907|UniProtKB=D0NHI2'	''	'Diphthine synthase'	'Phytophthora infestans'	'EnsemblGenome:PITG_11907'	'PITG_11907'	''	''	''	''	'PTN000853920'
'THAPS|Gene=Thaps20788|UniProtKB=B8BQN6'	''	'Methyltransferase'	'Thalassiosira pseudonana'	'Gene:Thaps20788'	'THAPSDRAFT_20788'	''	''	''	''	'PTN000853919'
'PHYPA|Gene=PHYPADRAFT_198807|UniProtKB=A9TVZ2'	''	'Predicted protein'	'Physcomitrella patens'	'Gene:PHYPADRAFT_198807'	'PHYPADRAFT_198807'	''	''	''	''	'PTN000853926'
'LEIMA|EnsemblGenome=LmjF.31.1610|UniProtKB=Q4Q6A1'	''	'Diphthine synthase-like protein'	'Leishmania major'	'EnsemblGenome:LmjF.31.1610'	'LMJF_31_1610'	''	''	''	''	'PTN000094331'
'TRYB2|Gene=Tb927.4.4650|UniProtKB=Q583F0'	''	'Diphthine synthase, putative'	'Trypanosoma brucei'	'Gene:Tb927.4.4650'	'Tb927.4.4650'	''	''	''	''	'PTN002248189'
'SCHPO|PomBase=SPCC576.14|UniProtKB=O74898'	''	'Diphthine methyl ester synthase'	'Schizosaccharomyces pombe'	'PomBase:SPCC576.14'	'dph5'	''	''	''	''	'PTN000094324'
'ORYSJ|EnsemblGenome=OS03G0355800|UniProtKB=Q10L98'	''	'Diphthine synthase, putative, expressed'	'Oryza sativa'	'EnsemblGenome:OS03G0355800'	'Os03g0355800'	''	''	''	''	'PTN000094335'
'BRAFL|Gene=BRAFLDRAFT_126365|UniProtKB=C3YA13'	''	'Putative uncharacterized protein'	'Branchiostoma floridae'	'Gene:BRAFLDRAFT_126365'	'BRAFLDRAFT_126365'	''	''	''	''	'PTN000853886'
'ASHGO|EnsemblGenome=AGOS_AFR123W|UniProtKB=Q754E7'	''	'Diphthine methyl ester synthase'	'Ashbya gossypii'	'EnsemblGenome:AGOS_AFR123W'	'DPH5'	''	''	''	''	'PTN000094320'
'CRYNJ|EnsemblGenome=CNF03650|UniProtKB=Q5KEZ6'	''	'Diphthine synthase, putative'	'Cryptococcus neoformans'	'EnsemblGenome:CNF03650'	'CNF03650'	''	''	''	''	'PTN000853910'
'HUMAN|HGNC=24270|UniProtKB=Q9H2P9'	''	'Diphthine methyl ester synthase'	'Homo sapiens'	'HGNC:24270'	'DPH5'	''	''	''	''	'PTN000094286'
'METJA|EnsemblGenome=MJ_1274|UniProtKB=Q58670'	''	'Diphthine synthase'	'Methanocaldococcus jannaschii'	'EnsemblGenome:MJ_1274'	'dphB'	''	''	''	''	'PTN000853930'
'CHLRE|EnsemblGenome=CHLREDRAFT_122908|UniProtKB=A8JG68'	''	'Predicted protein (Fragment)'	'Chlamydomonas reinhardtii'	'EnsemblGenome:CHLREDRAFT_122908'	'CHLREDRAFT_122908'	''	''	''	''	'PTN000094333'
'DAPPU|EnsemblGenome=DAPPUDRAFT_331033|UniProtKB=E9HLA8'	''	'Putative uncharacterized protein'	'Daphnia pulex'	'EnsemblGenome:DAPPUDRAFT_331033'	'DAPPUDRAFT_331033'	''	''	''	''	'PTN002248186'
'CIOIN|Ensembl=ENSCING00000009185|UniProtKB=F6YM02'	''	'Uncharacterized protein'	'Ciona intestinalis'	'Ensembl:ENSCING00000009185'	'LOC100181968'	''	''	''	''	'PTN001329528'
'FELCA|Ensembl=ENSFCAG00000022542|UniProtKB=M3WW82'	''	'Uncharacterized protein'	'Felis catus'	'Ensembl:ENSFCAG00000022542'	'DPH5'	''	''	''	''	'PTN001654323'
'USTMA|Gene=UMAG_04406|UniProtKB=A0A0D1C034'	''	'Chromosome 14, whole genome shotgun sequence'	'Ustilago maydis'	'Gene:UMAG_04406'	'UMAG_04406'	''	''	''	''	'PTN002248188'
'CANAL|Gene=CGD=CAL0004115|UniProtKB=Q59NX9'	''	'Diphthine methyl ester synthase'	'Candida albicans'	'Gene:CGD=CAL0004115'	'DPH5'	''	''	''	''	'PTN000853902'
'MONDO|Ensembl=ENSMODG00000003370|UniProtKB=F6ZPK7'	''	'Uncharacterized protein'	'Monodelphis domestica'	'Ensembl:ENSMODG00000003370'	'DPH5'	''	''	''	''	'PTN001329525'
'SORBI|EnsemblGenome=Sb01g035105|UniProtKB=C5WZQ6'	''	'Putative uncharacterized protein Sb01g035105 (Fragment)'	'Sorghum bicolor'	'EnsemblGenome:Sb01g035105'	'Sb01g035105'	''	''	''	''	'PTN001654328'
'SOYBN|EnsemblGenome=GLYMA20G01730|UniProtKB=K7N0Q6'	''	'Uncharacterized protein'	'Glycine max'	'EnsemblGenome:GLYMA20G01730'	''	''	''	''	''	'PTN001654335'
'PANTR|Ensembl=ENSPTRG00000001012|UniProtKB=H2PZI0'	''	'DPH5 homolog'	'Pan troglodytes'	'Ensembl:ENSPTRG00000001012'	'DPH5'	''	''	''	''	'PTN000094287'
'MACMU|Ensembl=ENSMMUG00000003730|UniProtKB=F6S1H6'	''	'Diphthine synthase isoform a'	'Macaca mulatta'	'Ensembl:ENSMMUG00000003730'	'DPH5'	''	''	''	''	'PTN000094288'
'POPTR|EnsemblGenome=POPTR_0002s02530|UniProtKB=B9GQW4'	''	'Uncharacterized protein'	'Populus trichocarpa'	'EnsemblGenome:POPTR_0002s02530'	'POPTR_0002s02530g'	''	''	''	''	'PTN002248190'
'XENTR|Gene=Xenbase=XB-GENE-965468|UniProtKB=Q6DEZ3'	''	'DPH5 homolog'	'Xenopus tropicalis'	'Gene:Xenbase=XB-GENE-965468'	'dph5'	''	''	''	''	'PTN000094298'
'ORNAN|Ensembl=ENSOANG00000004360|UniProtKB=F6Q8D4'	''	'Uncharacterized protein'	'Ornithorhynchus anatinus'	'Ensembl:ENSOANG00000004360'	'DPH5'	''	''	''	''	'PTN000094296'
'DICDI|dictyBase=DDB_G0276115|UniProtKB=Q75JG8'	''	'Diphthine methyl ester synthase'	'Dictyostelium discoideum'	'dictyBase:DDB_G0276115'	'dph5'	''	''	''	''	'PTN000094327'
'MONBE|Gene=33663|UniProtKB=A9V6F4'	''	'Predicted protein'	'Monosiga brevicollis'	'Gene:33663'	'33663'	''	''	''	''	'PTN000853896'
'YARLI|EnsemblGenome=YALI0_F17138g|UniProtKB=Q6C1E0'	''	'Diphthine methyl ester synthase'	'Yarrowia lipolytica'	'EnsemblGenome:YALI0_F17138g'	'DPH5'	''	''	''	''	'PTN000853904'
'CHICK|Ensembl=ENSGALG00000005229|UniProtKB=F1P418'	''	'Uncharacterized protein'	'Gallus gallus'	'Ensembl:ENSGALG00000005229'	'DPH5'	''	''	''	''	'PTN000094297'
'SULSO|EnsemblGenome=SSO0953|UniProtKB=Q97TX8'	''	'Diphthine synthase'	'Sulfolobus solfataricus'	'EnsemblGenome:SSO0953'	'dphB'	''	''	''	''	'PTN000094344'
'BRADI|EnsemblGenome=BRADI1G62230|UniProtKB=I1H5E2'	''	'Uncharacterized protein'	'Brachypodium distachyon'	'EnsemblGenome:BRADI1G62230'	'BRADI1G62230'	''	''	''	''	'PTN001654326'
'STRPU|EnsemblGenome=SPU_027420|UniProtKB=W4ZGW1'	''	'Uncharacterized protein'	'Strongylocentrotus purpuratus'	'EnsemblGenome:SPU_027420'	'Sp-Dph5'	''	''	''	''	'PTN000853887'
'TAKRU|Ensembl=ENSTRUG00000009702|UniProtKB=H2TI80'	''	'Uncharacterized protein'	'Takifugu rubripes'	'Ensembl:ENSTRUG00000009702'	'LOC101065858'	''	''	''	''	'PTN000094300'
'PRIPA|Gene=PPA22735|UniProtKB=H3FKD0'	''	'Uncharacterized protein'	'Pristionchus pacificus'	'Gene:PPA22735'	'WBGene00112289'	''	''	''	''	'PTN000853889'
'PHANO|EnsemblGenome=SNOG_03141|UniProtKB=Q0UYM3'	''	'Putative uncharacterized protein'	'Phaeosphaeria nodorum'	'EnsemblGenome:SNOG_03141'	'SNOG_03141'	''	''	''	''	'PTN000853908'
'SOLLC|EnsemblGenome=Solyc04g081310.2|UniProtKB=K4BVL0'	''	'Uncharacterized protein'	'Solanum lycopersicum'	'EnsemblGenome:Solyc04g081310.2'	'Solyc04g081310.2'	''	''	''	''	'PTN001654331'
'BATDJ|Gene=BATDEDRAFT_30589|UniProtKB=F4P9U2'	''	'Putative uncharacterized protein'	'Batrachochytrium dendrobatidis'	'Gene:BATDEDRAFT_30589'	'BATDEDRAFT_30589'	''	''	''	''	'PTN000853913'
'HALSA|EnsemblGenome=VNG_1118G|UniProtKB=Q9HQK6'	''	'Diphthine synthase'	'Halobacterium salinarum'	'EnsemblGenome:VNG_1118G'	'dphB'	''	''	''	''	'PTN000853931'
'MOUSE|MGI=MGI=1916990|UniProtKB=Q9CWQ0'	''	'Diphthine methyl ester synthase'	'Mus musculus'	'MGI:MGI=1916990'	'Dph5'	''	''	''	''	'PTN000094290'
'VITVI|EnsemblGenome=VIT_18s0001g14080|UniProtKB=E0CQ41'	''	'Putative uncharacterized protein'	'Vitis vinifera'	'EnsemblGenome:VIT_18s0001g14080'	'VIT_18s0001g14080'	''	''	''	''	'PTN001654333'
'CAEEL|WormBase=WBGene00007194|UniProtKB=Q17514'	''	'B0491.7'	'Caenorhabditis elegans'	'WormBase:WBGene00007194'	'B0491.7'	''	''	''	''	'PTN000094311'
'IXOSC|EnsemblGenome=ISCW015932|UniProtKB=B7P2M4'	''	'Diphthine synthase, putative'	'Ixodes scapularis'	'EnsemblGenome:ISCW015932'	'IscW_ISCW015932'	''	''	''	''	'PTN000853893'
'ANOGA|EnsemblGenome=AGAP004412|UniProtKB=Q7QA67'	''	'AGAP004412-PA'	'Anopheles gambiae'	'EnsemblGenome:AGAP004412'	'AgaP_AGAP004412'	''	''	''	''	'PTN000094315'
'SCHMA|EnsemblGenome=Smp_025570|UniProtKB=G4VPC1'	''	'Putative diphthine synthase'	'Schistosoma mansoni'	'EnsemblGenome:Smp_025570'	'Smp_025570.1'	''	''	''	''	'PTN000853894'
'METAC|EnsemblGenome=MA_1370|UniProtKB=Q8TR14'	''	'Diphthine synthase'	'Methanosarcina acetivorans'	'EnsemblGenome:MA_1370'	'dphB'	''	''	''	''	'PTN000094345'
'PIG|Ensembl=ENSSSCG00000006859|UniProtKB=F1S569'	''	'Uncharacterized protein'	'Sus scrofa'	'Ensembl:ENSSSCG00000006859'	'DPH5'	''	''	''	''	'PTN001329523'
'RAT|RGD=1307867|UniProtKB=Q569A7'	''	'DPH5 homolog (S. cerevisiae)'	'Rattus norvegicus'	'RGD:1307867'	'Dph5'	''	''	''	''	'PTN000094291'
'NEUCR|EnsemblGenome=EFNCRG00000007141|UniProtKB=Q7S949'	''	'Diphthine methyl ester synthase'	'Neurospora crassa'	'EnsemblGenome:EFNCRG00000007141'	'dph-5'	''	''	''	''	'PTN000094323'
'DANRE|ZFIN=ZDB-GENE-041114-85|UniProtKB=F1QHI1'	''	'Uncharacterized protein'	'Danio rerio'	'ZFIN:ZDB-GENE-041114-85'	'dph5'	''	''	''	''	'PTN000094302'
'ARATH|TAIR=AT4G31790|UniProtKB=O81769'	''	'Probable diphthine methyl ester synthase'	'Arabidopsis thaliana'	'TAIR:AT4G31790'	'At4g31790'	''	''	''	''	'PTN001329532'
'SORBI|EnsemblGenome=Sb01g035110|UniProtKB=C5WZQ7'	''	'Putative uncharacterized protein Sb01g035110'	'Sorghum bicolor'	'EnsemblGenome:Sb01g035110'	'Sb01g035110'	''	''	''	''	'PTN001654329'
'YEAST|SGD=S000004162|UniProtKB=P32469'	''	'Diphthine methyl ester synthase'	'Saccharomyces cerevisiae'	'SGD:S000004162'	'DPH5'	''	''	''	''	'PTN000094319'
'SCLS1|Gene=SS1G_09828|UniProtKB=A7EWW9'	''	'Putative uncharacterized protein'	'Sclerotinia sclerotiorum'	'Gene:SS1G_09828'	'SS1G_09828'	''	''	''	''	'PTN000853907'
'PYRKO|EnsemblGenome=TK0106|UniProtKB=Q5JFE7'	''	'Diphthine synthase'	'Pyrococcus kodakaraensis'	'EnsemblGenome:TK0106'	'dphB'	''	''	''	''	'PTN000853932'
'CAEBR|Gene=CBG02918|UniProtKB=A8WT81'	''	'Protein CBG02918'	'Caenorhabditis briggsae'	'Gene:CBG02918'	'CBG02918'	''	''	''	''	'PTN000094312'
'PLAF7|EnsemblGenome=PF10_0087|UniProtKB=Q8IJV5'	''	'Diphthine synthase'	'Plasmodium falciparum'	'EnsemblGenome:PF10_0087'	'PF10_0087'	''	''	''	''	'PTN000853917'