'Protein_Id'	'sf_name'	'definition'	'organism'	'gene_id'	'gene_symbol'	'Molecular function'	'Biological process'	'Cellular component'	'Protein class'	'Public_node_id'
'AN246'	'SUBFAMILY NOT NAMED'	''	''	''	''	'GO:0003677=DNA binding;GO:0016853=isomerase activity;GO:0016462=pyrophosphatase activity;GO:0003824=catalytic activity;GO:0005488=binding;GO:0003916=DNA topoisomerase activity;GO:0003676=nucleic acid binding;GO:0016787=hydrolase activity'	'GO:0008152=metabolic process;GO:0007059=chromosome segregation;GO:0006260=DNA replication;GO:0006139=nucleobase-containing compound metabolic process;GO:0006259=DNA metabolic process;GO:0006807=nitrogen compound metabolic process;GO:0009058=biosynthetic process;GO:0044238=primary metabolic process;GO:0009987=cellular process;GO:0009056=catabolic process;GO:0006796=phosphate-containing compound metabolic process'	'GO:0032991=macromolecular complex;GO:0043234=protein complex;GO:0044464=cell part;GO:0005622=intracellular'	'PC00095=enzyme modulator;PC00017=DNA topoisomerase;PC00171=nucleic acid binding;PC00135=isomerase;PC00009=DNA binding protein'	'PTN001607000'
'STRR6|EnsemblGenome=spr0756|UniProtKB=Q8DQB5'	''	'DNA topoisomerase 4 subunit B'	'Streptococcus pneumoniae'	'EnsemblGenome:spr0756'	'parE'	''	''	''	''	'PTN001607001'
'STAA8|EnsemblGenome=SAOUHSC_01351|UniProtKB=Q2FYS5'	''	'DNA topoisomerase 4 subunit B'	'Staphylococcus aureus'	'EnsemblGenome:SAOUHSC_01351'	'parE'	''	''	''	''	'PTN001607004'
'BACCR|EnsemblGenome=BC_3597|UniProtKB=Q81AH1'	''	'DNA topoisomerase 4 subunit B'	'Bacillus cereus'	'EnsemblGenome:BC_3597'	'parE'	''	''	''	''	'PTN001607006'
'LISMO|Gene=CAC99364|UniProtKB=Q8Y7J1'	''	'DNA topoisomerase 4 subunit B'	'Listeria monocytogenes'	'Gene:CAC99364'	'parE'	''	''	''	''	'PTN001607003'
'BACSU|EnsemblGenome=BSU18090|UniProtKB=Q59192'	''	'DNA topoisomerase 4 subunit B'	'Bacillus subtilis'	'EnsemblGenome:BSU18090'	'parE'	''	''	''	''	'PTN000019015'
'AN157'	'DNA TOPOISOMERASE 2, MITOCHONDRIAL'	''	''	''	''	'GO:0003677=DNA binding;GO:0016853=isomerase activity;GO:0016462=pyrophosphatase activity;GO:0003824=catalytic activity;GO:0005488=binding;GO:0003916=DNA topoisomerase activity;GO:0003676=nucleic acid binding;GO:0016787=hydrolase activity'	'GO:0000003=reproduction;GO:0016043=cellular component organization;GO:0007059=chromosome segregation;GO:0006260=DNA replication;GO:0006259=DNA metabolic process;GO:0006807=nitrogen compound metabolic process;GO:0009058=biosynthetic process;GO:0044238=primary metabolic process;GO:0006796=phosphate-containing compound metabolic process;GO:0008152=metabolic process;GO:0050789=regulation of biological process;GO:0006139=nucleobase-containing compound metabolic process;GO:0006996=organelle organization;GO:0007126=meiosis;GO:0051726=regulation of cell cycle;GO:0009056=catabolic process;GO:0009987=cellular process;GO:0006310=DNA recombination;GO:0007049=cell cycle;GO:0065007=biological regulation'	'GO:0043226=organelle;GO:0032991=macromolecular complex;GO:0005634=nucleus;GO:0043234=protein complex;GO:0044464=cell part;GO:0005622=intracellular'	'PC00095=enzyme modulator;PC00017=DNA topoisomerase;PC00171=nucleic acid binding;PC00135=isomerase;PC00009=DNA binding protein'	'PTN000808013'
'DICPU|Gene=DICPUDRAFT_28071|UniProtKB=F0ZB94'	''	'DNA topoisomerase 2'	'Dictyostelium purpureum'	'Gene:DICPUDRAFT_28071'	'DICPUDRAFT_28071'	''	''	''	''	'PTN000808014'
'DICDI|dictyBase=DDB_G0279737|UniProtKB=P90520'	''	'DNA topoisomerase 2, mitochondrial'	'Dictyostelium discoideum'	'dictyBase:DDB_G0279737'	'top2mt'	''	''	''	''	'PTN000018980'
'AN0'	'DNA GYRASE SUBUNIT B'	''	''	''	''	'GO:0003677=DNA binding;GO:0016853=isomerase activity;GO:0016462=pyrophosphatase activity;GO:0003824=catalytic activity;GO:0005488=binding;GO:0003916=DNA topoisomerase activity;GO:0003676=nucleic acid binding;GO:0016787=hydrolase activity'	'GO:0008152=metabolic process;GO:0007059=chromosome segregation;GO:0006260=DNA replication;GO:0006139=nucleobase-containing compound metabolic process;GO:0006259=DNA metabolic process;GO:0006807=nitrogen compound metabolic process;GO:0009058=biosynthetic process;GO:0044238=primary metabolic process;GO:0009987=cellular process;GO:0009056=catabolic process;GO:0006796=phosphate-containing compound metabolic process'	'GO:0032991=macromolecular complex;GO:0043234=protein complex;GO:0044464=cell part;GO:0005622=intracellular'	'PC00095=enzyme modulator;PC00017=DNA topoisomerase;PC00171=nucleic acid binding;PC00135=isomerase;PC00009=DNA binding protein'	'PTN000018885'
'RHOBA|EnsemblGenome=RB9109|UniProtKB=Q7UM28'	''	'DNA gyrase subunit B'	'Rhodopirellula baltica'	'EnsemblGenome:RB9109'	'gyrB'	''	''	''	''	'PTN000808061'
'ECOLI|EcoGene=EG10424|UniProtKB=P0AES6'	''	'DNA gyrase subunit B'	'Escherichia coli'	'EcoGene:EG10424'	'gyrB'	''	''	''	''	'PTN000808066'
'SYNY3|EnsemblGenome=BAA17720|UniProtKB=P77966'	''	'DNA gyrase subunit B'	'Synechocystis'	'EnsemblGenome:BAA17720'	'gyrB'	''	''	''	''	'PTN002228860'
'STRCO|EnsemblGenome=CAB92994|UniProtKB=P35886'	''	'DNA gyrase subunit B'	'Streptomyces coelicolor'	'EnsemblGenome:CAB92994'	'gyrB'	''	''	''	''	'PTN002228854'
'GEOSL|EnsemblGenome=GSU0003|UniProtKB=Q74H89'	''	'DNA gyrase subunit B'	'Geobacter sulfurreducens'	'EnsemblGenome:GSU0003'	'gyrB'	''	''	''	''	'PTN000019031'
'NEMVE|EnsemblGenome=NEMVEDRAFT_v1g225783|UniProtKB=A8DVR1'	''	'Predicted protein'	'Nematostella vectensis'	'EnsemblGenome:NEMVEDRAFT_v1g225783'	'v1g225783'	''	''	''	''	'PTN000808041'
'CHLTR|EnsemblGenome=CT_190|UniProtKB=O84193'	''	'DNA gyrase subunit B'	'Chlamydia trachomatis'	'EnsemblGenome:CT_190'	'gyrB'	''	''	''	''	'PTN000019028'
'VIBCH|EnsemblGenome=VC_0015|UniProtKB=Q9KVX3'	''	'DNA gyrase subunit B'	'Vibrio cholerae'	'EnsemblGenome:VC_0015'	'gyrB'	''	''	''	''	'PTN001607034'
'THEMA|EnsemblGenome=TM_0833|UniProtKB=P77993'	''	'DNA gyrase subunit B'	'Thermotoga maritima'	'EnsemblGenome:TM_0833'	'gyrB'	''	''	''	''	'PTN000019020'
'CHLAA|EnsemblGenome=Caur_3009|UniProtKB=A9WGP2'	''	'DNA gyrase subunit B'	'Chloroflexus aurantiacus'	'EnsemblGenome:Caur_3009'	'gyrB'	''	''	''	''	'PTN000019022'
'METAC|EnsemblGenome=MA_1584|UniProtKB=Q8TQG0'	''	'DNA gyrase subunit B'	'Methanosarcina acetivorans'	'EnsemblGenome:MA_1584'	'gyrB'	''	''	''	''	'PTN000019008'
'GLOVI|Gene=BAC90447|UniProtKB=Q7NHM9'	''	'DNA gyrase subunit B'	'Gloeobacter violaceus'	'Gene:BAC90447'	'gyrB'	''	''	''	''	'PTN000019023'
'DEIRA|EnsemblGenome=DR_0906|UniProtKB=Q9RVW5'	''	'DNA gyrase, subunit B'	'Deinococcus radiodurans'	'EnsemblGenome:DR_0906'	'DR_0906'	''	''	''	''	'PTN000019021'
'COXBU|EnsemblGenome=CBU_0004|UniProtKB=Q83FD5'	''	'DNA gyrase subunit B'	'Coxiella burnetii'	'EnsemblGenome:CBU_0004'	'gyrB'	''	''	''	''	'PTN001607035'
'SALTY|EnsemblGenome=STM3835|UniProtKB=P0A2I3'	''	'DNA gyrase subunit B'	'Salmonella typhimurium'	'EnsemblGenome:STM3835'	'gyrB'	''	''	''	''	'PTN001607040'
'MYCTU|EnsemblGenome=Rv0005|UniProtKB=P9WG45'	''	'DNA gyrase subunit B'	'Mycobacterium tuberculosis'	'EnsemblGenome:Rv0005'	'gyrB'	''	''	''	''	'PTN002228855'
'XANCP|EnsemblGenome=XCC0004|UniProtKB=Q8PEH2'	''	'DNA gyrase subunit B'	'Xanthomonas campestris'	'EnsemblGenome:XCC0004'	'gyrB'	''	''	''	''	'PTN001607037'
'LISMO|Gene=CAC98221|UniProtKB=Q8YAV7'	''	'DNA gyrase subunit B'	'Listeria monocytogenes'	'Gene:CAC98221'	'gyrB'	''	''	''	''	'PTN001607030'
'BACTN|EnsemblGenome=BT_3429|UniProtKB=Q8A277'	''	'DNA gyrase subunit B'	'Bacteroides thetaiotaomicron'	'EnsemblGenome:BT_3429'	'gyrB'	''	''	''	''	'PTN000019027'
'STRCO|Gene=CAA18520|UniProtKB=O69998'	''	'Putative DNA gyrase subunit B'	'Streptomyces coelicolor'	'Gene:CAA18520'	'SCO5822'	''	''	''	''	'PTN000019018'
'LEPIN|EnsemblGenome=LA_4194|UniProtKB=Q8EYL9'	''	'DNA gyrase subunit B'	'Leptospira interrogans'	'EnsemblGenome:LA_4194'	'LA_4194'	''	''	''	''	'PTN000019025'
'PSEAE|EnsemblGenome=PA0004|UniProtKB=Q9I7C2'	''	'DNA gyrase subunit B'	'Pseudomonas aeruginosa'	'EnsemblGenome:PA0004'	'gyrB'	''	''	''	''	'PTN002228864'
'HAEIN|EnsemblGenome=HI_0567|UniProtKB=P43701'	''	'DNA gyrase subunit B'	'Haemophilus influenzae'	'EnsemblGenome:HI_0567'	'gyrB'	''	''	''	''	'PTN001607038'
'STRR6|EnsemblGenome=spr0715|UniProtKB=P0A4M0'	''	'DNA gyrase subunit B'	'Streptococcus pneumoniae'	'EnsemblGenome:spr0715'	'gyrB'	''	''	''	''	'PTN001607028'
'CHLRE|EnsemblGenome=CHLREDRAFT_114600|UniProtKB=A8IIG8'	''	'DNA gyrase subunit B-like protein (Fragment)'	'Chlamydomonas reinhardtii'	'EnsemblGenome:CHLREDRAFT_114600'	'TOP3'	''	''	''	''	'PTN000019001'
'CLOBH|EnsemblGenome=CLC_2646|UniProtKB=A5I5K6'	''	'DNA gyrase subunit B'	'Clostridium botulinum'	'EnsemblGenome:CLC_2646'	'gyrB'	''	''	''	''	'PTN001607025'
'BACCR|EnsemblGenome=BC_0005|UniProtKB=Q81JD1'	''	'DNA gyrase subunit B'	'Bacillus cereus'	'EnsemblGenome:BC_0005'	'gyrB'	''	''	''	''	'PTN001607033'
'PLAF7|EnsemblGenome=PFL1915w|UniProtKB=Q8I528'	''	'Dna gyrase subunit b, putative'	'Plasmodium falciparum'	'EnsemblGenome:PFL1915w'	'PFL1915w'	''	''	''	''	'PTN000808044'
'BACSU|EnsemblGenome=BSU00060|UniProtKB=P05652'	''	'DNA gyrase subunit B'	'Bacillus subtilis'	'EnsemblGenome:BSU00060'	'gyrB'	''	''	''	''	'PTN000019016'
'SHEON|EnsemblGenome=SO_0011|UniProtKB=Q8EKS9'	''	'DNA gyrase subunit B'	'Shewanella oneidensis'	'EnsemblGenome:SO_0011'	'gyrB'	''	''	''	''	'PTN001607036'
'AQUAE|EnsemblGenome=aq_1026|UniProtKB=O67137'	''	'DNA gyrase subunit B'	'Aquifex aeolicus'	'EnsemblGenome:aq_1026'	'gyrB'	''	''	''	''	'PTN000019029'
'FUSNN|EnsemblGenome=FN2126|UniProtKB=Q8RHB1'	''	'DNA gyrase subunit B'	'Fusobacterium nucleatum'	'EnsemblGenome:FN2126'	'gyrB'	''	''	''	''	'PTN000808064'
'TRIAD|EnsemblGenome=TriadG63040|UniProtKB=B3SFQ4'	''	'Putative uncharacterized protein (Fragment)'	'Trichoplax adhaerens'	'EnsemblGenome:TriadG63040'	'TRIADDRAFT_63040'	''	''	''	''	'PTN002228849'
'DICTD|EnsemblGenome=Dtur_1547|UniProtKB=B8E2H7'	''	'DNA gyrase subunit B'	'Dictyoglomus turgidum'	'EnsemblGenome:Dtur_1547'	'gyrB'	''	''	''	''	'PTN000808063'
'THEYD|EnsemblGenome=THEYE_A0017|UniProtKB=B5YGU1'	''	'DNA gyrase subunit B'	'Thermodesulfovibrio yellowstonii'	'EnsemblGenome:THEYE_A0017'	'gyrB'	''	''	''	''	'PTN000808062'
'HALSA|EnsemblGenome=VNG_0887G|UniProtKB=Q9HR30'	''	'DNA gyrase subunit B'	'Halobacterium salinarum'	'EnsemblGenome:VNG_0887G'	'gyrB'	''	''	''	''	'PTN000808052'
'THAPS|Gene=Thaps39924|UniProtKB=B8BY03'	''	'DNA topoisomerase'	'Thalassiosira pseudonana'	'Gene:Thaps39924'	'TopoII_1'	''	''	''	''	'PTN000808045'
'STRPU|EnsemblGenome=SPU_027881|UniProtKB=W4ZI67'	''	'Uncharacterized protein'	'Strongylocentrotus purpuratus'	'EnsemblGenome:SPU_027881'	'Sp-Top2b_1'	''	''	''	''	'PTN002228848'
'IXOSC|EnsemblGenome=ISCW024091|UniProtKB=B7P6J4'	''	'DNA topoisomerase 2 (Fragment)'	'Ixodes scapularis'	'EnsemblGenome:ISCW024091'	'IscW_ISCW024091'	''	''	''	''	'PTN000808068'
'BRAJA|Gene=BAC46088|UniProtKB=Q89W70'	''	'DNA gyrase subunit B'	'Bradyrhizobium japonicum'	'Gene:BAC46088'	'gyrB'	''	''	''	''	'PTN000019034'
'LEPIN|EnsemblGenome=LA_0005|UniProtKB=Q8FA30'	''	'DNA gyrase subunit B'	'Leptospira interrogans'	'EnsemblGenome:LA_0005'	'gyrB'	''	''	''	''	'PTN000019026'
'STAA8|EnsemblGenome=SAOUHSC_00005|UniProtKB=Q2G274'	''	'DNA gyrase subunit B'	'Staphylococcus aureus'	'EnsemblGenome:SAOUHSC_00005'	'gyrB'	''	''	''	''	'PTN001607031'
'AN43'	'DNA TOPOISOMERASE 2-BETA'	''	''	''	''	'GO:0003677=DNA binding;GO:0016853=isomerase activity;GO:0016462=pyrophosphatase activity;GO:0003824=catalytic activity;GO:0005488=binding;GO:0003916=DNA topoisomerase activity;GO:0003676=nucleic acid binding;GO:0016787=hydrolase activity'	'GO:0000003=reproduction;GO:0016043=cellular component organization;GO:0007059=chromosome segregation;GO:0006260=DNA replication;GO:0006259=DNA metabolic process;GO:0006807=nitrogen compound metabolic process;GO:0009058=biosynthetic process;GO:0044238=primary metabolic process;GO:0006796=phosphate-containing compound metabolic process;GO:0008152=metabolic process;GO:0050789=regulation of biological process;GO:0006139=nucleobase-containing compound metabolic process;GO:0006996=organelle organization;GO:0007126=meiosis;GO:0051726=regulation of cell cycle;GO:0009056=catabolic process;GO:0009987=cellular process;GO:0006310=DNA recombination;GO:0007049=cell cycle;GO:0065007=biological regulation'	'GO:0043226=organelle;GO:0032991=macromolecular complex;GO:0005634=nucleus;GO:0043234=protein complex;GO:0044464=cell part;GO:0005622=intracellular'	'PC00095=enzyme modulator;PC00017=DNA topoisomerase;PC00171=nucleic acid binding;PC00135=isomerase;PC00009=DNA binding protein'	'PTN000018895'
'PANTR|Ensembl=ENSPTRG00000014699|UniProtKB=H2QM73'	''	'DNA topoisomerase 2'	'Pan troglodytes'	'Ensembl:ENSPTRG00000014699'	'TOP2B'	''	''	''	''	'PTN000018930'
'MONDO|Ensembl=ENSMODG00000014954|UniProtKB=F7D0D3'	''	'DNA topoisomerase 2'	'Monodelphis domestica'	'Ensembl:ENSMODG00000014954'	'TOP2B'	''	''	''	''	'PTN000018940'
'MACMU|Ensembl=ENSMMUG00000007371|UniProtKB=F7E5A9'	''	'DNA topoisomerase 2'	'Macaca mulatta'	'Ensembl:ENSMMUG00000007371'	'TOP2B'	''	''	''	''	'PTN000018931'
'MOUSE|MGI=MGI=98791|UniProtKB=Q64511'	''	'DNA topoisomerase 2-beta'	'Mus musculus'	'MGI:MGI=98791'	'Top2b'	''	''	''	''	'PTN000018933'
'HORSE|Ensembl=ENSECAG00000005608|UniProtKB=F7CL38'	''	'DNA topoisomerase 2 (Fragment)'	'Equus caballus'	'Ensembl:ENSECAG00000005608'	'TOP2B'	''	''	''	''	'PTN001300567'
'CANFA|Ensembl=ENSCAFG00000005702|UniProtKB=F1PRA7'	''	'DNA topoisomerase 2 (Fragment)'	'Canis familiaris'	'Ensembl:ENSCAFG00000005702'	'TOP2B'	''	''	''	''	'PTN000018939'
'DANRE|ZFIN=ZDB-GENE-041008-136|UniProtKB=Q1LUT2'	''	'DNA topoisomerase 2'	'Danio rerio'	'ZFIN:ZDB-GENE-041008-136'	'top2b'	''	''	''	''	'PTN000018946'
'BOVIN|Ensembl=ENSBTAG00000004593|UniProtKB=F1MU48'	''	'DNA topoisomerase 2 (Fragment)'	'Bos taurus'	'Ensembl:ENSBTAG00000004593'	'TOP2B'	''	''	''	''	'PTN000018938'
'ORNAN|Ensembl=ENSOANG00000012235|UniProtKB=F7FGH6'	''	'DNA topoisomerase 2'	'Ornithorhynchus anatinus'	'Ensembl:ENSOANG00000012235'	'TOP2B'	''	''	''	''	'PTN000018941'
'XENTR|Gene=Xenbase=XB-GENE-970178|UniProtKB=F6ZPV6'	''	'DNA topoisomerase 2'	'Xenopus tropicalis'	'Gene:Xenbase=XB-GENE-970178'	'top2a'	''	''	''	''	'PTN000018916'
'CHICK|Gene=TOP2B|UniProtKB=O42131'	''	'DNA topoisomerase 2-beta'	'Gallus gallus'	'Gene:TOP2B'	'TOP2B'	''	''	''	''	'PTN000018942'
'PIG|Ensembl=ENSSSCG00000011213|UniProtKB=F1RS45'	''	'DNA topoisomerase 2'	'Sus scrofa'	'Ensembl:ENSSSCG00000011213'	'TOP2B'	''	''	''	''	'PTN001300566'
'TAKRU|Ensembl=ENSTRUG00000007059|UniProtKB=H2SY53'	''	'DNA topoisomerase 2'	'Takifugu rubripes'	'Ensembl:ENSTRUG00000007059'	'LOC101075827'	''	''	''	''	'PTN000018945'
'ANOCA|Ensembl=ENSACAG00000008939|UniProtKB=H9GEY4'	''	'DNA topoisomerase 2'	'Anolis carolinensis'	'Ensembl:ENSACAG00000008939'	'TOP2B'	''	''	''	''	'PTN001300569'
'XENTR|Gene=Xenbase=XB-GENE-940716|UniProtKB=F7BGW3'	''	'DNA topoisomerase 2'	'Xenopus tropicalis'	'Gene:Xenbase=XB-GENE-940716'	'top2b'	''	''	''	''	'PTN000018943'
'HUMAN|HGNC=11990|UniProtKB=Q02880'	''	'DNA topoisomerase 2-beta'	'Homo sapiens'	'HGNC:11990'	'TOP2B'	''	''	''	''	'PTN000018929'
'FELCA|Ensembl=ENSFCAG00000031328|UniProtKB=M3X192'	''	'DNA topoisomerase 2'	'Felis catus'	'Ensembl:ENSFCAG00000031328'	'TOP2B'	''	''	''	''	'PTN001606950'
'AN316'	'DNA TOPOISOMERASE 4 SUBUNIT B'	''	''	''	''	'GO:0003677=DNA binding;GO:0016853=isomerase activity;GO:0016462=pyrophosphatase activity;GO:0003824=catalytic activity;GO:0005488=binding;GO:0003916=DNA topoisomerase activity;GO:0003676=nucleic acid binding;GO:0016787=hydrolase activity'	'GO:0008152=metabolic process;GO:0007059=chromosome segregation;GO:0006260=DNA replication;GO:0006139=nucleobase-containing compound metabolic process;GO:0006259=DNA metabolic process;GO:0006807=nitrogen compound metabolic process;GO:0009058=biosynthetic process;GO:0044238=primary metabolic process;GO:0009987=cellular process;GO:0009056=catabolic process;GO:0006796=phosphate-containing compound metabolic process'	'GO:0032991=macromolecular complex;GO:0043234=protein complex;GO:0044464=cell part;GO:0005622=intracellular'	'PC00095=enzyme modulator;PC00017=DNA topoisomerase;PC00171=nucleic acid binding;PC00135=isomerase;PC00009=DNA binding protein'	'PTN000019036'
'SALTY|EnsemblGenome=STM3181|UniProtKB=P0A2I5'	''	'DNA topoisomerase 4 subunit B'	'Salmonella typhimurium'	'EnsemblGenome:STM3181'	'parE'	''	''	''	''	'PTN001606996'
'YERPE|EnsemblGenome=YP_2983|UniProtKB=Q7CGH6'	''	'DNA topoisomerase 4 subunit B'	'Yersinia pestis'	'EnsemblGenome:YP_2983'	'parE'	''	''	''	''	'PTN001606998'
'VIBCH|EnsemblGenome=VC_2431|UniProtKB=Q9KPD9'	''	'DNA topoisomerase 4 subunit B'	'Vibrio cholerae'	'EnsemblGenome:VC_2431'	'parE'	''	''	''	''	'PTN001606990'
'SHEON|EnsemblGenome=SO_3899|UniProtKB=Q8EAK3'	''	'DNA topoisomerase 4 subunit B'	'Shewanella oneidensis'	'EnsemblGenome:SO_3899'	'parE'	''	''	''	''	'PTN001606992'
'PSEAE|EnsemblGenome=PA4967|UniProtKB=Q9HUJ8'	''	'DNA topoisomerase 4 subunit B'	'Pseudomonas aeruginosa'	'EnsemblGenome:PA4967'	'parE'	''	''	''	''	'PTN002228862'
'YERPE|EnsemblGenome=DJ56_2229|UniProtKB=Q7CGH6'	''	'DNA topoisomerase 4 subunit B'	'Yersinia pestis'	'EnsemblGenome:DJ56_2229'	'parE'	''	''	''	''	'PTN002228863'
'COXBU|EnsemblGenome=CBU_0064|UniProtKB=Q83F84'	''	'DNA topoisomerase 4 subunit B'	'Coxiella burnetii'	'EnsemblGenome:CBU_0064'	'parE'	''	''	''	''	'PTN001606991'
'HAEIN|EnsemblGenome=HI_1528|UniProtKB=P43703'	''	'DNA topoisomerase 4 subunit B'	'Haemophilus influenzae'	'EnsemblGenome:HI_1528'	'parE'	''	''	''	''	'PTN001606994'
'XANCP|EnsemblGenome=XCC1695|UniProtKB=Q8P9Z8'	''	'DNA topoisomerase 4 subunit B'	'Xanthomonas campestris'	'EnsemblGenome:XCC1695'	'parE'	''	''	''	''	'PTN001606993'
'YERPE|EnsemblGenome=y3511|UniProtKB=Q7CGH6'	''	'DNA topoisomerase 4 subunit B'	'Yersinia pestis'	'EnsemblGenome:y3511'	'parE'	''	''	''	''	'PTN001606999'
'ECOLI|EcoGene=EG10687|UniProtKB=P20083'	''	'DNA topoisomerase 4 subunit B'	'Escherichia coli'	'EcoGene:EG10687'	'parE'	''	''	''	''	'PTN000019038'
'AN271'	'DNA GYRASE B3-RELATED'	''	''	''	''	'GO:0003677=DNA binding;GO:0016853=isomerase activity;GO:0016462=pyrophosphatase activity;GO:0003824=catalytic activity;GO:0005488=binding;GO:0003916=DNA topoisomerase activity;GO:0003676=nucleic acid binding;GO:0016787=hydrolase activity'	'GO:0008152=metabolic process;GO:0007059=chromosome segregation;GO:0006260=DNA replication;GO:0006139=nucleobase-containing compound metabolic process;GO:0006259=DNA metabolic process;GO:0006807=nitrogen compound metabolic process;GO:0009058=biosynthetic process;GO:0044238=primary metabolic process;GO:0009987=cellular process;GO:0009056=catabolic process;GO:0006796=phosphate-containing compound metabolic process'	'GO:0032991=macromolecular complex;GO:0043234=protein complex;GO:0044464=cell part;GO:0005622=intracellular'	'PC00095=enzyme modulator;PC00017=DNA topoisomerase;PC00171=nucleic acid binding;PC00135=isomerase;PC00009=DNA binding protein'	'PTN000808046'
'BRADI|EnsemblGenome=BRADI2G10040|UniProtKB=I1HEB4'	''	'Uncharacterized protein'	'Brachypodium distachyon'	'EnsemblGenome:BRADI2G10040'	'BRADI2G10040'	''	''	''	''	'PTN001607011'
'VITVI|EnsemblGenome=VIT_08s0007g05120|UniProtKB=D7TIQ6'	''	'Putative uncharacterized protein'	'Vitis vinifera'	'EnsemblGenome:VIT_08s0007g05120'	'VIT_08s0007g05120'	''	''	''	''	'PTN001607016'
'ARATH|TAIR=AT3G10270|UniProtKB=Q9SS38'	''	'DNA gyrase subunit B, chloroplastic'	'Arabidopsis thaliana'	'TAIR:AT3G10270'	'GYRBC'	''	''	''	''	'PTN000808047'
'SOLLC|EnsemblGenome=Solyc12g021230.1|UniProtKB=K4DDP2'	''	'Uncharacterized protein'	'Solanum lycopersicum'	'EnsemblGenome:Solyc12g021230.1'	'Solyc12g021230.1'	''	''	''	''	'PTN001607014'
'PHYPA|Gene=PHYPADRAFT_224019|UniProtKB=A9TNV0'	''	'Predicted protein'	'Physcomitrella patens'	'Gene:PHYPADRAFT_224019'	'PHYPADRAFT_224019'	''	''	''	''	'PTN000808050'
'SORBI|EnsemblGenome=Sb10g016352|UniProtKB=C5Z2H5'	''	'Putative uncharacterized protein Sb10g016352 (Fragment)'	'Sorghum bicolor'	'EnsemblGenome:Sb10g016352'	'Sb10g016352'	''	''	''	''	'PTN001606982'
'SOYBN|EnsemblGenome=GLYMA19G31030|UniProtKB=I1N8R8'	''	'Uncharacterized protein'	'Glycine max'	'EnsemblGenome:GLYMA19G31030'	''	''	''	''	''	'PTN001607020'
'POPTR|EnsemblGenome=POPTR_0016s03560|UniProtKB=B9IHQ8'	''	'DNA topoisomerase 2 family protein'	'Populus trichocarpa'	'EnsemblGenome:POPTR_0016s03560'	'POPTR_0016s03560g'	''	''	''	''	'PTN002228859'
'SORBI|EnsemblGenome=Sb10g016452|UniProtKB=C5Z2Y7'	''	'Putative uncharacterized protein Sb10g016452 (Fragment)'	'Sorghum bicolor'	'EnsemblGenome:Sb10g016452'	'Sb10g016452'	''	''	''	''	'PTN001606983'
'SORBI|EnsemblGenome=Sb03g010630|UniProtKB=C5XGL0'	''	'Putative uncharacterized protein Sb03g010630'	'Sorghum bicolor'	'EnsemblGenome:Sb03g010630'	'Sb03g010630'	''	''	''	''	'PTN001607012'
'ARATH|TAIR=AT5G04110|UniProtKB=Q8VY11'	''	'DNA gyrase B3'	'Arabidopsis thaliana'	'TAIR:AT5G04110'	'GYRB3'	''	''	''	''	'PTN000019005'
'ORYSJ|EnsemblGenome=OS01G0268300|UniProtKB=Q5NBJ3'	''	'DNA gyrase subunit B, chloroplastic/mitochondrial'	'Oryza sativa'	'EnsemblGenome:OS01G0268300'	'GYRB'	''	''	''	''	'PTN000019003'
'SOYBN|EnsemblGenome=GLYMA03G28290|UniProtKB=I1JN48'	''	'Uncharacterized protein'	'Glycine max'	'EnsemblGenome:GLYMA03G28290'	''	''	''	''	''	'PTN001607019'
'ARATH|TAIR=AT5G04130|UniProtKB=Q94BZ7'	''	'DNA gyrase subunit B, mitochondrial'	'Arabidopsis thaliana'	'TAIR:AT5G04130'	'GYRBM'	''	''	''	''	'PTN000019006'
'PHYPA|Gene=PHYPADRAFT_156248|UniProtKB=A9U4H8'	''	'Predicted protein'	'Physcomitrella patens'	'Gene:PHYPADRAFT_156248'	'PHYPADRAFT_156248'	''	''	''	''	'PTN000808049'
'POPTR|EnsemblGenome=POPTR_0006s03770|UniProtKB=B9H929'	''	'Uncharacterized protein'	'Populus trichocarpa'	'EnsemblGenome:POPTR_0006s03770'	'POPTR_0006s03770g'	''	''	''	''	'PTN002228858'
'AN3'	'DNA TOPOISOMERASE 2'	''	''	''	''	'GO:0003677=DNA binding;GO:0016853=isomerase activity;GO:0016462=pyrophosphatase activity;GO:0003824=catalytic activity;GO:0005488=binding;GO:0003916=DNA topoisomerase activity;GO:0003676=nucleic acid binding;GO:0016787=hydrolase activity'	'GO:0000003=reproduction;GO:0016043=cellular component organization;GO:0007059=chromosome segregation;GO:0006260=DNA replication;GO:0006259=DNA metabolic process;GO:0006807=nitrogen compound metabolic process;GO:0009058=biosynthetic process;GO:0044238=primary metabolic process;GO:0006796=phosphate-containing compound metabolic process;GO:0008152=metabolic process;GO:0050789=regulation of biological process;GO:0006139=nucleobase-containing compound metabolic process;GO:0006996=organelle organization;GO:0007126=meiosis;GO:0051726=regulation of cell cycle;GO:0009056=catabolic process;GO:0009987=cellular process;GO:0006310=DNA recombination;GO:0007049=cell cycle;GO:0065007=biological regulation'	'GO:0043226=organelle;GO:0032991=macromolecular complex;GO:0005634=nucleus;GO:0043234=protein complex;GO:0044464=cell part;GO:0005622=intracellular'	'PC00095=enzyme modulator;PC00017=DNA topoisomerase;PC00171=nucleic acid binding;PC00135=isomerase;PC00009=DNA binding protein'	'PTN000018888'
'STRPU|EnsemblGenome=SPU_004587|UniProtKB=W4XMF6'	''	'DNA topoisomerase 2'	'Strongylocentrotus purpuratus'	'EnsemblGenome:SPU_004587'	'Sp-Top2b'	''	''	''	''	'PTN000807964'
'DAPPU|EnsemblGenome=DAPPUDRAFT_670|UniProtKB=E9G706'	''	'Putative uncharacterized protein (Fragment)'	'Daphnia pulex'	'EnsemblGenome:DAPPUDRAFT_670'	'DAPPUDRAFT_670'	''	''	''	''	'PTN002228813'
'DAPPU|EnsemblGenome=DAPPUDRAFT_315940|UniProtKB=E9GC36'	''	'Putative uncharacterized protein'	'Daphnia pulex'	'EnsemblGenome:DAPPUDRAFT_315940'	'DAPPUDRAFT_315940'	''	''	''	''	'PTN002228814'
'CAEEL|WormBase=WBGene00019884|UniProtKB=P34534'	''	'Putative DNA topoisomerase 2, mitochondrial'	'Caenorhabditis elegans'	'WormBase:WBGene00019884'	'R05D3.12'	''	''	''	''	'PTN000018957'
'SCLS1|EnsemblGenome=SS1G_01930|UniProtKB=A7E9F0'	''	'DNA topoisomerase 2'	'Sclerotinia sclerotiorum'	'EnsemblGenome:SS1G_01930'	'SS1G_01930'	''	''	''	''	'PTN000808006'
'NEMVE|EnsemblGenome=NEMVEDRAFT_v1g94148|UniProtKB=A7RUU3'	''	'Predicted protein (Fragment)'	'Nematostella vectensis'	'EnsemblGenome:NEMVEDRAFT_v1g94148'	'v1g94148'	''	''	''	''	'PTN002228828'
'SORBI|EnsemblGenome=Sb10g016438|UniProtKB=C5Z2Y6'	''	'Putative uncharacterized protein Sb10g016438 (Fragment)'	'Sorghum bicolor'	'EnsemblGenome:Sb10g016438'	'Sb10g016438'	''	''	''	''	'PTN001606968'
'DAPPU|EnsemblGenome=DAPPUDRAFT_332921|UniProtKB=E9HRB9'	''	'DNA topoisomerase 2'	'Daphnia pulex'	'EnsemblGenome:DAPPUDRAFT_332921'	'DAPPUDRAFT_332921'	''	''	''	''	'PTN002228819'
'PHANO|EnsemblGenome=SNOG_06355|UniProtKB=Q0UPF9'	''	'DNA topoisomerase 2'	'Phaeosphaeria nodorum'	'EnsemblGenome:SNOG_06355'	'SNOG_06355'	''	''	''	''	'PTN000808007'
'PRIPA|Gene=PPA14440|UniProtKB=H3EX84'	''	'Uncharacterized protein'	'Pristionchus pacificus'	'Gene:PPA14440'	'WBGene00103994'	''	''	''	''	'PTN001300599'
'DAPPU|EnsemblGenome=DAPPUDRAFT_333905|UniProtKB=E9HU61'	''	'DNA topoisomerase 2 (Fragment)'	'Daphnia pulex'	'EnsemblGenome:DAPPUDRAFT_333905'	'DAPPUDRAFT_333905'	''	''	''	''	'PTN002228820'
'TRIVA|Gene=TVAG_038880|UniProtKB=A2E5K0'	''	'DNA topoisomerase 2'	'Trichomonas vaginalis'	'Gene:TVAG_038880'	'TVAG_038880'	''	''	''	''	'PTN000808033'
'THAPS|Gene=Thaps36522|UniProtKB=B8C9P0'	''	'DNA topoisomerase 2 (Fragment)'	'Thalassiosira pseudonana'	'Gene:Thaps36522'	'TOP2'	''	''	''	''	'PTN000808019'
'PLAF7|EnsemblGenome=PF14_0316|UniProtKB=Q8ILC8'	''	'DNA topoisomerase 2'	'Plasmodium falciparum'	'EnsemblGenome:PF14_0316'	'PF14_0316'	''	''	''	''	'PTN000808016'
'USTMA|Gene=UMAG_03501|UniProtKB=A0A0D1DXS4'	''	'DNA topoisomerase 2'	'Ustilago maydis'	'Gene:UMAG_03501'	'UMAG_03501'	''	''	''	''	'PTN002228830'
'DAPPU|EnsemblGenome=DAPPUDRAFT_315718|UniProtKB=E9GAL2'	''	'Putative uncharacterized protein'	'Daphnia pulex'	'EnsemblGenome:DAPPUDRAFT_315718'	'DAPPUDRAFT_315718'	''	''	''	''	'PTN002228815'
'PRIPA|Gene=PPA14442|UniProtKB=H3EX86'	''	'Uncharacterized protein'	'Pristionchus pacificus'	'Gene:PPA14442'	'WBGene00103996'	''	''	''	''	'PTN002228810'
'CAEBR|Gene=CBG18156|UniProtKB=A8XT54'	''	'DNA topoisomerase 2'	'Caenorhabditis briggsae'	'Gene:CBG18156'	'CBG18156'	''	''	''	''	'PTN001300580'
'YARLI|EnsemblGenome=YALI0_D23969g|UniProtKB=Q6C7Z9'	''	'DNA topoisomerase 2'	'Yarrowia lipolytica'	'EnsemblGenome:YALI0_D23969g'	'YALI0_D23969g'	''	''	''	''	'PTN000808003'
'DAPPU|EnsemblGenome=DAPPUDRAFT_329527|UniProtKB=E9HGV5'	''	'DNA topoisomerase 2'	'Daphnia pulex'	'EnsemblGenome:DAPPUDRAFT_329527'	'DAPPUDRAFT_329527'	''	''	''	''	'PTN002228827'
'POPTR|EnsemblGenome=POPTR_0001s27120|UniProtKB=B9GFC4'	''	'DNA topoisomerase 2'	'Populus trichocarpa'	'EnsemblGenome:POPTR_0001s27120'	'POPTR_0001s27120g'	''	''	''	''	'PTN002228843'
'DAPPU|EnsemblGenome=DAPPUDRAFT_315938|UniProtKB=E9GC34'	''	'Putative uncharacterized protein'	'Daphnia pulex'	'EnsemblGenome:DAPPUDRAFT_315938'	'DAPPUDRAFT_315938'	''	''	''	''	'PTN002228821'
'PRIPA|Gene=PPA14439|UniProtKB=H3EX83'	''	'Histone-lysine N-methyltransferase'	'Pristionchus pacificus'	'Gene:PPA14439'	'WBGene00103993'	''	''	''	''	'PTN002228811'
'ORYSJ|Gene=P0459B01.29|UniProtKB=Q6Z8D9'	''	'DNA topoisomerase 2'	'Oryza sativa'	'Gene:P0459B01.29'	'P0459B01.29'	''	''	''	''	'PTN001300595'
'ARATH|TAIR=AT3G23890|UniProtKB=P30182'	''	'DNA topoisomerase 2'	'Arabidopsis thaliana'	'TAIR:AT3G23890'	'TOP2'	''	''	''	''	'PTN000018997'
'TETTS|EnsemblGenome=TTHERM_00456750|UniProtKB=I7MA91'	''	'DNA topoisomerase 2'	'Tetrahymena thermophila'	'EnsemblGenome:TTHERM_00456750'	'TTHERM_00456750'	''	''	''	''	'PTN002228837'
'GIAIC|EnsemblGenome=GL50803_16975|UniProtKB=E2RU90'	''	'DNA topoisomerase 2'	'Giardia intestinalis'	'EnsemblGenome:GL50803_16975'	'GL50803_16975'	''	''	''	''	'PTN000808032'
'STRPU|EnsemblGenome=SPU_006364|UniProtKB=W4XSG7'	''	'Uncharacterized protein'	'Strongylocentrotus purpuratus'	'EnsemblGenome:SPU_006364'	''	''	''	''	''	'PTN002228803'
'DAPPU|Gene=DAPPUDRAFT_47063|UniProtKB=E9G746'	''	'DNA topoisomerase 2 (Fragment)'	'Daphnia pulex'	'Gene:DAPPUDRAFT_47063'	'DAPPUDRAFT_47063'	''	''	''	''	'PTN001606957'
'SCHPO|PomBase=SPBC1A4.03c|UniProtKB=P08096'	''	'DNA topoisomerase 2'	'Schizosaccharomyces pombe'	'PomBase:SPBC1A4.03c'	'top2'	''	''	''	''	'PTN000018976'
'BRAFL|Gene=BRAFLDRAFT_67020|UniProtKB=C3YYJ6'	''	'Putative uncharacterized protein'	'Branchiostoma floridae'	'Gene:BRAFLDRAFT_67020'	'BRAFLDRAFT_67020'	''	''	''	''	'PTN002228801'
'TETTS|EnsemblGenome=TTHERM_01335310|UniProtKB=Q23CP4'	''	'DNA topoisomerase'	'Tetrahymena thermophila'	'EnsemblGenome:TTHERM_01335310'	'TTHERM_01335310'	''	''	''	''	'PTN000018985'
'STRPU|EnsemblGenome=SPU_018730|UniProtKB=W4YSE3'	''	'Uncharacterized protein'	'Strongylocentrotus purpuratus'	'EnsemblGenome:SPU_018730'	'Sp-Top2a'	''	''	''	''	'PTN002228804'
'SORBI|EnsemblGenome=Sb04g030880|UniProtKB=C5Y0E7'	''	'DNA topoisomerase 2'	'Sorghum bicolor'	'EnsemblGenome:Sb04g030880'	'Sb04g030880'	''	''	''	''	'PTN001606969'
'DAPPU|EnsemblGenome=DAPPUDRAFT_317439|UniProtKB=E9GFZ8'	''	'Putative uncharacterized protein'	'Daphnia pulex'	'EnsemblGenome:DAPPUDRAFT_317439'	'DAPPUDRAFT_317439'	''	''	''	''	'PTN002228822'
'DICDI|dictyBase=DDB_G0270418|UniProtKB=Q55BP5'	''	'Probable DNA topoisomerase 2'	'Dictyostelium discoideum'	'dictyBase:DDB_G0270418'	'top2'	''	''	''	''	'PTN000018981'
'TETTS|EnsemblGenome=TTHERM_00192100|UniProtKB=I7MJQ8'	''	'DNA topoisomerase II'	'Tetrahymena thermophila'	'EnsemblGenome:TTHERM_00192100'	'TTHERM_00192100'	''	''	''	''	'PTN002228835'
'ORYSJ|EnsemblGenome=OS02G0699700|UniProtKB=Q0DYE1'	''	'DNA topoisomerase 2 (Fragment)'	'Oryza sativa'	'EnsemblGenome:OS02G0699700'	'Os02g0699700'	''	''	''	''	'PTN000018996'
'SOYBN|EnsemblGenome=GLYMA15G43170|UniProtKB=I1MJQ7'	''	'DNA topoisomerase 2'	'Glycine max'	'EnsemblGenome:GLYMA15G43170'	''	''	''	''	''	'PTN001606977'
'IXOSC|EnsemblGenome=ISCW016225|UniProtKB=B7P0P1'	''	'DNA topoisomerase 2'	'Ixodes scapularis'	'EnsemblGenome:ISCW016225'	'IscW_ISCW016225'	''	''	''	''	'PTN000807996'
'DAPPU|EnsemblGenome=DAPPUDRAFT_323396|UniProtKB=E9GYS0'	''	'DNA topoisomerase 2'	'Daphnia pulex'	'EnsemblGenome:DAPPUDRAFT_323396'	'DAPPUDRAFT_323396'	''	''	''	''	'PTN002228816'
'NEUCR|Gene=NCU06338|UniProtKB=V5IMJ3'	''	'DNA topoisomerase 2'	'Neurospora crassa'	'Gene:NCU06338'	'NCU06338'	''	''	''	''	'PTN000018975'
'CRYNJ|EnsemblGenome=CNA03600|UniProtKB=Q5KP97'	''	'DNA topoisomerase 2'	'Cryptococcus neoformans'	'EnsemblGenome:CNA03600'	'CNA03600'	''	''	''	''	'PTN000808009'
'BATDJ|Gene=BATDEDRAFT_18312|UniProtKB=F4NTP0'	''	'DNA topoisomerase 2 (Fragment)'	'Batrachochytrium dendrobatidis'	'Gene:BATDEDRAFT_18312'	'BATDEDRAFT_18312'	''	''	''	''	'PTN000808012'
'CANAL|Gene=CGD=CAL0005199|UniProtKB=Q5A1E7'	''	'DNA topoisomerase 2'	'Candida albicans'	'Gene:CGD=CAL0005199'	'TOP2'	''	''	''	''	'PTN001300584'
'EMENI|EnsemblGenome=CADANIAG00003686|UniProtKB=Q5B224'	''	'DNA topoisomerase 2'	'Emericella nidulans'	'EnsemblGenome:CADANIAG00003686'	'AN5406.2'	''	''	''	''	'PTN001300586'
'ASHGO|EnsemblGenome=AGOS_AER410W|UniProtKB=Q755V8'	''	'DNA topoisomerase 2'	'Ashbya gossypii'	'EnsemblGenome:AGOS_AER410W'	'AGOS_AER410W'	''	''	''	''	'PTN000018972'
'CIOIN|Ensembl=ENSCING00000008347|UniProtKB=F7AKG2'	''	'DNA topoisomerase 2'	'Ciona intestinalis'	'Ensembl:ENSCING00000008347'	'ci-htf-1'	''	''	''	''	'PTN001300578'
'YEAST|SGD=S000005032|UniProtKB=P06786'	''	'DNA topoisomerase 2'	'Saccharomyces cerevisiae'	'SGD:S000005032'	'TOP2'	''	''	''	''	'PTN000018971'
'PUCGT|EnsemblGenome=PGTG_00741|UniProtKB=E3JRR8'	''	'DNA topoisomerase 2'	'Puccinia graminis'	'EnsemblGenome:PGTG_00741'	'PGTG_00741'	''	''	''	''	'PTN000807948'
'SORBI|EnsemblGenome=Sb10g016510|UniProtKB=C5Z2Z1'	''	'Putative uncharacterized protein Sb10g016510'	'Sorghum bicolor'	'EnsemblGenome:Sb10g016510'	'Sb10g016510'	''	''	''	''	'PTN001606967'
'THAPS|Gene=Thaps36420|UniProtKB=B8C9L4'	''	'DNA topoisomerase 2'	'Thalassiosira pseudonana'	'Gene:Thaps36420'	'THAPSDRAFT_36420'	''	''	''	''	'PTN000808021'
'PHYIT|EnsemblGenome=PITG_07874|UniProtKB=D0NA12'	''	'DNA topoisomerase 2'	'Phytophthora infestans'	'EnsemblGenome:PITG_07874'	'PITG_07874'	''	''	''	''	'PTN000808025'
'SOYBN|EnsemblGenome=GLYMA18G24230|UniProtKB=K7MSA1'	''	'Uncharacterized protein (Fragment)'	'Glycine max'	'EnsemblGenome:GLYMA18G24230'	''	''	''	''	''	'PTN002228840'
'STRPU|EnsemblGenome=SPU_027880|UniProtKB=W4ZI66'	''	'Uncharacterized protein'	'Strongylocentrotus purpuratus'	'EnsemblGenome:SPU_027880'	''	''	''	''	''	'PTN002228806'
'CHLRE|EnsemblGenome=CHLREDRAFT_38019|UniProtKB=A8JD08'	''	'DNA topoisomerase 2 (Fragment)'	'Chlamydomonas reinhardtii'	'EnsemblGenome:CHLREDRAFT_38019'	'TOP2'	''	''	''	''	'PTN000018994'
'DICPU|Gene=DICPUDRAFT_4475|UniProtKB=F0ZNB2'	''	'DNA topoisomerase 2 (Fragment)'	'Dictyostelium purpureum'	'Gene:DICPUDRAFT_4475'	'DICPUDRAFT_4475'	''	''	''	''	'PTN001300588'
'SCHMA|EnsemblGenome=Smp_065840|UniProtKB=G4VPA9'	''	'DNA topoisomerase 2'	'Schistosoma mansoni'	'EnsemblGenome:Smp_065840'	'Smp_065840'	''	''	''	''	'PTN000807997'
'TETTS|EnsemblGenome=TTHERM_00825440|UniProtKB=I7M5X3'	''	'DNA topoisomerase 2'	'Tetrahymena thermophila'	'EnsemblGenome:TTHERM_00825440'	'TTHERM_00825440'	''	''	''	''	'PTN002228836'
'BRADI|EnsemblGenome=BRADI3G52470|UniProtKB=I1ICW6'	''	'DNA topoisomerase 2'	'Brachypodium distachyon'	'EnsemblGenome:BRADI3G52470'	'BRADI3G52470'	''	''	''	''	'PTN001606964'
'SOLLC|EnsemblGenome=Solyc01g087500.2|UniProtKB=K4AYE0'	''	'DNA topoisomerase 2'	'Solanum lycopersicum'	'EnsemblGenome:Solyc01g087500.2'	'Solyc01g087500.2'	''	''	''	''	'PTN001606971'
'DAPPU|EnsemblGenome=DAPPUDRAFT_30330|UniProtKB=E9G724'	''	'Putative uncharacterized protein (Fragment)'	'Daphnia pulex'	'EnsemblGenome:DAPPUDRAFT_30330'	'DAPPUDRAFT_30330'	''	''	''	''	'PTN002228823'
'POPTR|EnsemblGenome=POPTR_0009s06380|UniProtKB=B9HNR6'	''	'DNA topoisomerase 2'	'Populus trichocarpa'	'EnsemblGenome:POPTR_0009s06380'	'POPTR_0009s06380g'	''	''	''	''	'PTN002228842'
'DAPPU|EnsemblGenome=DAPPUDRAFT_333898|UniProtKB=E9HU54'	''	'DNA topoisomerase 2'	'Daphnia pulex'	'EnsemblGenome:DAPPUDRAFT_333898'	'DAPPUDRAFT_333898'	''	''	''	''	'PTN002228817'
'PUCGT|EnsemblGenome=PGTG_22746|UniProtKB=H6QVG6'	''	'DNA topoisomerase 2'	'Puccinia graminis'	'EnsemblGenome:PGTG_22746'	'PGTG_22746'	''	''	''	''	'PTN002228832'
'TRYB2|Gene=Tb11.01.3390|UniProtKB=Q383C4'	''	'DNA topoisomerase 2'	'Trypanosoma brucei'	'Gene:Tb11.01.3390'	'Tb11.01.3390'	''	''	''	''	'PTN002228838'
'DAPPU|EnsemblGenome=DAPPUDRAFT_104556|UniProtKB=E9GMM0'	''	'Putative uncharacterized protein'	'Daphnia pulex'	'EnsemblGenome:DAPPUDRAFT_104556'	'DAPPUDRAFT_104556'	''	''	''	''	'PTN002228824'
'PHYIT|EnsemblGenome=PITG_01300|UniProtKB=D0MV61'	''	'DNA topoisomerase 2'	'Phytophthora infestans'	'EnsemblGenome:PITG_01300'	'PITG_01300'	''	''	''	''	'PTN000808023'
'PHYIT|EnsemblGenome=PITG_07823|UniProtKB=D0N9W9'	''	'DNA topoisomerase 2'	'Phytophthora infestans'	'EnsemblGenome:PITG_07823'	'PITG_07823'	''	''	''	''	'PTN000808024'
'DAPPU|EnsemblGenome=DAPPUDRAFT_102310|UniProtKB=E9GG16'	''	'Putative uncharacterized protein'	'Daphnia pulex'	'EnsemblGenome:DAPPUDRAFT_102310'	'DAPPUDRAFT_102310'	''	''	''	''	'PTN002228818'
'PHYPA|Gene=PHYPADRAFT_134247|UniProtKB=A9SRT5'	''	'DNA topoisomerase 2 (Fragment)'	'Physcomitrella patens'	'Gene:PHYPADRAFT_134247'	'PHYPADRAFT_134247'	''	''	''	''	'PTN000808038'
'LEIMA|EnsemblGenome=LmjF.28.2280|UniProtKB=Q4Q836'	''	'DNA topoisomerase 2'	'Leishmania major'	'EnsemblGenome:LmjF.28.2280'	'LMJF_28_2280'	''	''	''	''	'PTN000018992'
'ENTHI|EnsemblGenome=EHI_120640|UniProtKB=Q6RCM0'	''	'DNA topoisomerase 2'	'Entamoeba histolytica'	'EnsemblGenome:EHI_120640'	'EHI_120640'	''	''	''	''	'PTN000018978'
'DAPPU|EnsemblGenome=DAPPUDRAFT_317722|UniProtKB=E9GGS6'	''	'Putative uncharacterized protein'	'Daphnia pulex'	'EnsemblGenome:DAPPUDRAFT_317722'	'DAPPUDRAFT_317722'	''	''	''	''	'PTN002228825'
'PRIPA|Gene=PPA24131|UniProtKB=H3FPB5'	''	'Uncharacterized protein'	'Pristionchus pacificus'	'Gene:PPA24131'	'WBGene00113685'	''	''	''	''	'PTN002228809'
'SORBI|EnsemblGenome=Sb01g048550|UniProtKB=C5WZY6'	''	'Putative uncharacterized protein Sb01g048550'	'Sorghum bicolor'	'EnsemblGenome:Sb01g048550'	'Sb01g048550'	''	''	''	''	'PTN002228839'
'VITVI|EnsemblGenome=VIT_13s0064g00560|UniProtKB=F6HBC4'	''	'DNA topoisomerase 2'	'Vitis vinifera'	'EnsemblGenome:VIT_13s0064g00560'	'VIT_13s0064g00560'	''	''	''	''	'PTN001606973'
'DAPPU|EnsemblGenome=DAPPUDRAFT_240289|UniProtKB=E9GC35'	''	'Putative uncharacterized protein'	'Daphnia pulex'	'EnsemblGenome:DAPPUDRAFT_240289'	'DAPPUDRAFT_240289'	''	''	''	''	'PTN002228826'
'STRPU|EnsemblGenome=SPU_013355|UniProtKB=W4YC78'	''	'Uncharacterized protein'	'Strongylocentrotus purpuratus'	'EnsemblGenome:SPU_013355'	''	''	''	''	''	'PTN002228805'
'DROME|FlyBase=FBgn0003732|UniProtKB=P15348'	''	'DNA topoisomerase 2'	'Drosophila melanogaster'	'FlyBase:FBgn0003732'	'Top2'	''	''	''	''	'PTN000018966'
'PHYPA|Gene=PHYPADRAFT_120620|UniProtKB=A9RWX5'	''	'DNA topoisomerase 2 (Fragment)'	'Physcomitrella patens'	'Gene:PHYPADRAFT_120620'	'PHYPADRAFT_120620'	''	''	''	''	'PTN000808037'
'TETTS|EnsemblGenome=TTHERM_00052080|UniProtKB=Q23CY2'	''	'DNA topoisomerase II'	'Tetrahymena thermophila'	'EnsemblGenome:TTHERM_00052080'	'TTHERM_00052080'	''	''	''	''	'PTN000018986'
'ORYSJ|EnsemblGenome=OS01G0234200|UniProtKB=Q9LGX8'	''	'DNA topoisomerase 2'	'Oryza sativa'	'EnsemblGenome:OS01G0234200'	'P0702F03.20'	''	''	''	''	'PTN001606963'
'SOYBN|EnsemblGenome=GLYMA10G11610|UniProtKB=I1L9S4'	''	'DNA topoisomerase 2'	'Glycine max'	'EnsemblGenome:GLYMA10G11610'	''	''	''	''	''	'PTN001606976'
'PUCGT|EnsemblGenome=PGTG_22747|UniProtKB=H6QVG7'	''	'DNA topoisomerase II'	'Puccinia graminis'	'EnsemblGenome:PGTG_22747'	'PGTG_22747'	''	''	''	''	'PTN002228833'
'TRIAD|EnsemblGenome=TriadG23201|UniProtKB=B3RRE6'	''	'DNA topoisomerase 2 (Fragment)'	'Trichoplax adhaerens'	'EnsemblGenome:TriadG23201'	'TRIADDRAFT_23201'	''	''	''	''	'PTN000807999'
'ANOGA|Gene=AgaP_AGAP008917|UniProtKB=Q7PWM2'	''	'DNA topoisomerase 2 (Fragment)'	'Anopheles gambiae'	'Gene:AgaP_AGAP008917'	'AgaP_AGAP008917'	''	''	''	''	'PTN001606956'
'AN219'	'SUBFAMILY NOT NAMED'	''	''	''	''	'GO:0003677=DNA binding;GO:0016853=isomerase activity;GO:0016462=pyrophosphatase activity;GO:0003824=catalytic activity;GO:0005488=binding;GO:0003916=DNA topoisomerase activity;GO:0003676=nucleic acid binding;GO:0016787=hydrolase activity'	'GO:0008152=metabolic process;GO:0007059=chromosome segregation;GO:0006260=DNA replication;GO:0006139=nucleobase-containing compound metabolic process;GO:0006259=DNA metabolic process;GO:0006807=nitrogen compound metabolic process;GO:0009058=biosynthetic process;GO:0044238=primary metabolic process;GO:0009987=cellular process;GO:0009056=catabolic process;GO:0006796=phosphate-containing compound metabolic process'	'GO:0032991=macromolecular complex;GO:0043234=protein complex;GO:0044464=cell part;GO:0005622=intracellular'	'PC00095=enzyme modulator;PC00017=DNA topoisomerase;PC00171=nucleic acid binding;PC00135=isomerase;PC00009=DNA binding protein'	'PTN002228844'
'TRYB2|Gene=Tb09.160.4090|UniProtKB=Q38EZ6'	''	'DNA topoisomerase 2'	'Trypanosoma brucei'	'Gene:Tb09.160.4090'	'Tb09.160.4090'	''	''	''	''	'PTN002228845'
'THAPS|Gene=Thaps263644|UniProtKB=B8C981'	''	'DNA topoisomerase 2 (Fragment)'	'Thalassiosira pseudonana'	'Gene:Thaps263644'	'TopoII_2'	''	''	''	''	'PTN000808020'
'LEIMA|EnsemblGenome=LmjF.15.1290|UniProtKB=Q4QF53'	''	'DNA topoisomerase 2'	'Leishmania major'	'EnsemblGenome:LmjF.15.1290'	'TOP2'	''	''	''	''	'PTN000018991'
'AN12'	'DNA TOPOISOMERASE 2-ALPHA'	''	''	''	''	'GO:0003677=DNA binding;GO:0016853=isomerase activity;GO:0016462=pyrophosphatase activity;GO:0003824=catalytic activity;GO:0005488=binding;GO:0003916=DNA topoisomerase activity;GO:0003676=nucleic acid binding;GO:0016787=hydrolase activity'	'GO:0000003=reproduction;GO:0016043=cellular component organization;GO:0007059=chromosome segregation;GO:0006260=DNA replication;GO:0006259=DNA metabolic process;GO:0006807=nitrogen compound metabolic process;GO:0009058=biosynthetic process;GO:0044238=primary metabolic process;GO:0006796=phosphate-containing compound metabolic process;GO:0008152=metabolic process;GO:0050789=regulation of biological process;GO:0006139=nucleobase-containing compound metabolic process;GO:0006996=organelle organization;GO:0007126=meiosis;GO:0051726=regulation of cell cycle;GO:0009056=catabolic process;GO:0009987=cellular process;GO:0006310=DNA recombination;GO:0007049=cell cycle;GO:0065007=biological regulation'	'GO:0043226=organelle;GO:0032991=macromolecular complex;GO:0005634=nucleus;GO:0043234=protein complex;GO:0044464=cell part;GO:0005622=intracellular'	'PC00095=enzyme modulator;PC00017=DNA topoisomerase;PC00171=nucleic acid binding;PC00135=isomerase;PC00009=DNA binding protein'	'PTN002228797'
'ANOCA|Ensembl=ENSACAG00000001904|UniProtKB=G1KAM2'	''	'DNA topoisomerase 2'	'Anolis carolinensis'	'Ensembl:ENSACAG00000001904'	'TOP2A'	''	''	''	''	'PTN001300576'
'CHICK|Gene=TOP2A|UniProtKB=O42130'	''	'DNA topoisomerase 2-alpha'	'Gallus gallus'	'Gene:TOP2A'	'TOP2A'	''	''	''	''	'PTN000018915'
'PANTR|Ensembl=ENSPTRG00000009122|UniProtKB=H2QCW5'	''	'DNA topoisomerase 2 (Fragment)'	'Pan troglodytes'	'Ensembl:ENSPTRG00000009122'	'TOP2A'	''	''	''	''	'PTN000018905'
'ORNAN|Ensembl=ENSOANG00000003053|UniProtKB=F7A8M1'	''	'DNA topoisomerase 2'	'Ornithorhynchus anatinus'	'Ensembl:ENSOANG00000003053'	'TOP2A'	''	''	''	''	'PTN000018914'
'DANRE|ZFIN=ZDB-GENE-030131-2453|UniProtKB=A8E7K3'	''	'Uncharacterized protein (Fragment)'	'Danio rerio'	'ZFIN:ZDB-GENE-030131-2453'	'top2a'	''	''	''	''	'PTN002228799'
'MOUSE|MGI=MGI=98790|UniProtKB=Q01320'	''	'DNA topoisomerase 2-alpha'	'Mus musculus'	'MGI:MGI=98790'	'Top2a'	''	''	''	''	'PTN000018908'
'RAT|RGD=62048|UniProtKB=P41516'	''	'DNA topoisomerase 2-alpha'	'Rattus norvegicus'	'RGD:62048'	'Top2a'	''	''	''	''	'PTN000018909'
'PIG|Ensembl=ENSSSCG00000017473|UniProtKB=O46374'	''	'DNA topoisomerase 2-alpha'	'Sus scrofa'	'Ensembl:ENSSSCG00000017473'	'TOP2A'	''	''	''	''	'PTN001300573'
'HUMAN|HGNC=11989|UniProtKB=P11388'	''	'DNA topoisomerase 2-alpha'	'Homo sapiens'	'HGNC:11989'	'TOP2A'	''	''	''	''	'PTN000018904'
'CANFA|Ensembl=ENSCAFG00000016090|UniProtKB=J9PAY8'	''	'DNA topoisomerase 2'	'Canis familiaris'	'Ensembl:ENSCAFG00000016090'	'TOP2A'	''	''	''	''	'PTN000018912'
'HORSE|Ensembl=ENSECAG00000013053|UniProtKB=F6ZLS2'	''	'DNA topoisomerase 2'	'Equus caballus'	'Ensembl:ENSECAG00000013053'	'TOP2A'	''	''	''	''	'PTN001300574'
'TAKRU|Ensembl=ENSTRUG00000016398|UniProtKB=H2UY95'	''	'DNA topoisomerase 2 (Fragment)'	'Takifugu rubripes'	'Ensembl:ENSTRUG00000016398'	'LOC101075432'	''	''	''	''	'PTN000018918'
'MONDO|Ensembl=ENSMODG00000013152|UniProtKB=F7ABY1'	''	'DNA topoisomerase 2'	'Monodelphis domestica'	'Ensembl:ENSMODG00000013152'	'TOP2A'	''	''	''	''	'PTN000018913'
'MACMU|Ensembl=ENSMMUG00000008941|UniProtKB=F7EVK2'	''	'DNA topoisomerase 2 (Fragment)'	'Macaca mulatta'	'Ensembl:ENSMMUG00000008941'	'TOP2A'	''	''	''	''	'PTN000018906'
'FELCA|Ensembl=ENSFCAG00000009642|UniProtKB=M3WBT9'	''	'DNA topoisomerase 2'	'Felis catus'	'Ensembl:ENSFCAG00000009642'	'TOP2A'	''	''	''	''	'PTN001606948'
'BOVIN|Ensembl=ENSBTAG00000019262|UniProtKB=F1MDU7'	''	'DNA topoisomerase 2'	'Bos taurus'	'Ensembl:ENSBTAG00000019262'	'TOP2A'	''	''	''	''	'PTN000758614'
'AN90'	'CIN-4-RELATED'	''	''	''	''	'GO:0003677=DNA binding;GO:0016853=isomerase activity;GO:0016462=pyrophosphatase activity;GO:0003824=catalytic activity;GO:0005488=binding;GO:0003916=DNA topoisomerase activity;GO:0003676=nucleic acid binding;GO:0016787=hydrolase activity'	'GO:0000003=reproduction;GO:0016043=cellular component organization;GO:0007059=chromosome segregation;GO:0006260=DNA replication;GO:0006259=DNA metabolic process;GO:0006807=nitrogen compound metabolic process;GO:0009058=biosynthetic process;GO:0044238=primary metabolic process;GO:0006796=phosphate-containing compound metabolic process;GO:0008152=metabolic process;GO:0050789=regulation of biological process;GO:0006139=nucleobase-containing compound metabolic process;GO:0006996=organelle organization;GO:0007126=meiosis;GO:0051726=regulation of cell cycle;GO:0009056=catabolic process;GO:0009987=cellular process;GO:0006310=DNA recombination;GO:0007049=cell cycle;GO:0065007=biological regulation'	'GO:0043226=organelle;GO:0032991=macromolecular complex;GO:0005634=nucleus;GO:0043234=protein complex;GO:0044464=cell part;GO:0005622=intracellular'	'PC00095=enzyme modulator;PC00017=DNA topoisomerase;PC00171=nucleic acid binding;PC00135=isomerase;PC00009=DNA binding protein'	'PTN000018959'
'CAEEL|WormBase=WBGene00022854|UniProtKB=G5ECQ8'	''	'CIN-4'	'Caenorhabditis elegans'	'WormBase:WBGene00022854'	'cin-4'	''	''	''	''	'PTN000018962'
'CAEBR|Gene=CBG02746|UniProtKB=A8WTL4'	''	'DNA topoisomerase 2'	'Caenorhabditis briggsae'	'Gene:CBG02746'	'CBG02746'	''	''	''	''	'PTN000018964'
'CAEEL|WormBase=WBGene00010785|UniProtKB=Q23670'	''	'Probable DNA topoisomerase 2'	'Caenorhabditis elegans'	'WormBase:WBGene00010785'	'K12D12.1'	''	''	''	''	'PTN000018963'
'CAEEL|WormBase=WBGene00021604|UniProtKB=Q9N4W3'	''	'Y46H3C.4'	'Caenorhabditis elegans'	'WormBase:WBGene00021604'	'CELE_Y46H3C.4'	''	''	''	''	'PTN000018961'
'AN239'	'SUBFAMILY NOT NAMED'	''	''	''	''	'GO:0003677=DNA binding;GO:0016853=isomerase activity;GO:0016462=pyrophosphatase activity;GO:0003824=catalytic activity;GO:0005488=binding;GO:0003916=DNA topoisomerase activity;GO:0003676=nucleic acid binding;GO:0016787=hydrolase activity'	'GO:0008152=metabolic process;GO:0007059=chromosome segregation;GO:0006260=DNA replication;GO:0006139=nucleobase-containing compound metabolic process;GO:0006259=DNA metabolic process;GO:0006807=nitrogen compound metabolic process;GO:0009058=biosynthetic process;GO:0044238=primary metabolic process;GO:0009987=cellular process;GO:0009056=catabolic process;GO:0006796=phosphate-containing compound metabolic process'	'GO:0032991=macromolecular complex;GO:0043234=protein complex;GO:0044464=cell part;GO:0005622=intracellular'	'PC00095=enzyme modulator;PC00017=DNA topoisomerase;PC00171=nucleic acid binding;PC00135=isomerase;PC00009=DNA binding protein'	'PTN000019010'
'CHLTR|EnsemblGenome=CT_661|UniProtKB=O84668'	''	'DNA Gyrase Subunit B'	'Chlamydia trachomatis'	'EnsemblGenome:CT_661'	'gyrB_2'	''	''	''	''	'PTN000019012'
'BACTN|EnsemblGenome=BT_3033|UniProtKB=Q8A3C1'	''	'DNA topoisomerase IV subunit B'	'Bacteroides thetaiotaomicron'	'EnsemblGenome:BT_3033'	'BT_3033'	''	''	''	''	'PTN000019011'