Gene Ontology Definition Changes

0 annotations

GO:0007249 : I-kappaB kinase/NF-kappaB cascade

OLD: A series of reactions initiated by the activation of the transcription factor NF-kappaB. NF-kappaB is sequestered by the inhibitor I-kappaB, and is released when I-kappaB is phosphorylated by activated I-kappaB kinase.
NEW: The process in which a signal is passed on to downstream components within the cell through the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB. The cascade begins with activation of IKK and ends with the regulation of transcription of target genes by NF-kappaB. In a resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.

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GO:0007252 : I-kappaB phosphorylation

OLD: The process of introducing a phosphate group into an I-kappaB protein.
NEW: The process of introducing a phosphate group into an inhibitor of kappa B (I-kappaB) protein. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing bound NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.

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GO:0007263 : nitric oxide mediated signal transduction

OLD: A series of molecular signals mediated by the detection of nitric oxide (NO).
NEW: A series of molecular signals mediated by nitric oxide (NO).

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GO:0008385 : IkappaB kinase complex

OLD: A protein serine/threonine kinase that phosphorylates IkappaB, thereby targeting this for proteasomal degradation and allowing the nuclear translocation of kB. Composed of alpha, beta and gamma subunits, the latter not having kinase activity but presumed to play a regulatory role.
NEW: A trimeric protein complex that phosphorylates inhibitory-kappaB (I-kappaB) proteins. The complex is composed of two kinase subunits (alpha and beta) and a regulatory gamma subunit (also called NEMO). In a resting state, NF-kappaB dimers are bound to inhibitory IKB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.

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GO:0010162 : seed dormancy process

(was seed dormancy)

OLD: The process in which a dormant state is induced, maintained and broken in a seed. Dormancy is characterized by a suspension of physiological activity that can be reactivated.
NEW: A dormancy process in which dormancy (sometimes called a dormant state) is induced, maintained or broken in a seed. Seed dormancy is a suspension of most physiological activity and growth in a seed, including the embryo contained therein, that can be reactivated. It often requires special conditions for reactivation, such as specific temperature, scarification, or leaching of inhibitors.

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GO:0022611 : dormancy process

OLD: The process in which a dormant state is induced, maintained or broken. Dormancy is characterized by a suspension of physiological activity.
NEW: A developmental process in which dormancy (sometimes called a dormant state) is induced, maintained or broken. Dormancy is a suspension of most physiological activity and growth that can be reactivated.

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GO:0033217 : regulation of transcription from RNA polymerase II promoter in response to iron ion starvation

OLD: Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is deprived of iron ions.
NEW: Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions.

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GO:0033256 : I-kappaB/NF-kappaB complex

OLD: A protein complex containing an I-kappaB protein and one or more copies of an NF-kappaB protein; mediates regulation of NF-kappaB activity by I-kappaB.
NEW: A protein complex containing an inhibitory-kappaB (I-kappaB/IKB) protein and one or more copies of an NF-kappaB protein. In the resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm.

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GO:0042599 : lamellar body

OLD: A membrane-bounded organelle, specialized for the storage and secretion various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome.
NEW: A membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome.

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GO:0070335 : aspartate binding

OLD: Interacting selectively and non-covalently with glutamate, the anion of 2-aminobutanedioic acid.
NEW: Interacting selectively and non-covalently with aspartate, the alpha-amino-acid anion of 2-aminobutanedioic acid that has formula C4H5NO4.

0 annotations

GO:0071847 : TNFSF11-mediated signaling pathway

OLD: A series of molecular signals generated as a consequence of TNFSF11 binding to a cell surface receptor.
NEW: A series of molecular signals generated as a consequence of tumor necrosis factor ligand superfamily member 11 (TNFSF11) binding to a cell surface receptor.

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GO:0090375 : negative regulation of transcription from RNA polymerase II promoter in response to iron ion starvation

OLD: Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is deprived of iron ions.
NEW: Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions.

0 annotations

GO:2000033 : regulation of seed dormancy process

(was regulation of seed dormancy)

OLD: Any process that modulates the frequency, rate or extent of seed dormancy.
NEW: Any process that modulates the frequency, rate or extent of seed dormancy process.