MBTPS2
S2P
UniProt:O43462 MBTPS2
KIAA0091
MBTPS1
S1P
SKI1
UniProt:Q14703 MBTPS1
Dissociation of ATF6-alpha:BiP Complex
Translocation of ATF6-alpha to the Golgi
Cleavage of ATF6-alpha by S1P
Cleavage of ATF6-alpha by S2P
Translocation of ATF6-alpha to the Nucleus
Dissociation of IRE1:BiP heterodimer
Dimerization of IRE1
Autophosphorylation of IRE1 dimer
ADP Binding by Phosphorylated IRE1 Homodimer
Cleavage of Xbp1 mRNA by IRE1alpha and Splicing of Cleaved Xbp1 mRNA
Translation and translocation of XBP1(S) to the Nucleus
Dissociation of PERK:BiP Heterodimer
Dimerization of PERK
Phosphorylation of eIF2-alpha by PERK
Unfolded Protein Response
Activation of Chaperones by ATF6-alpha
Activation of Chaperone Genes by ATF6-alpha
Activation of Chaperones by IRE1alpha
Activation of Chaperone Genes by XBP1(S)
PERK regulated gene expression
Activation of Genes by ATF4
Translation and translocation of ATF4
Expression of ATF3
Expression of Asparagine Synthetase
Expression of CCL2
Expression of HERPUD
Expression of IGFBP1
Expression of IL-8
Expression of BIP (78 kDa Glucose-regulated protein, GRP78, HSPA5)
Expression of CHOP (DDIT3, GADD153)
Expression of Calreticulin
Expression of HSP90B1 (Endoplasmin)
Expression of Xbp1(S)
Expression of ACADVL
Expression of ADD1 (Adducin alpha)
Expression of ATP6VOD1
Expression of C19orf10
Expression of CTDSP2
Expression of CXXC1
Expression of Cullin-7
Expression of DCTN1
Expression of DDX11
Expression of DNAJB11
Expression of DNAJB9
Expression of EDEM
Expression of EXTL3
Expression of FKBP14
Expression of ARFGAP1 (GAP)
Expression of GFPT1
Expression of GOSR2
Expression of GSK3A
Expression of HDGF
Expression of HYOU1
Expression of KDELR3
Expression of KLHDC3
Expression of LMNA
Expression of PDIA5
Expression of PDIA6 (Protein disulfide-isomerase A6)
Expression of PLA2G4B
Expression of PPP2R5B
Expression of SERP1 (RAMP4)
Expression of SHC1
Expression of SRPR (SRP Receptor subunit alpha)
Expression of SRPRB (SRP Receptor subunit beta)
Expression of SSR1 (Trap alpha)
Expression of SULT1A3
Expression of SYVN1 (HRD1)
Expression of Sec12
Expression of Sec31A
Expression of TATDN2
Expression of TPP1
Expression of TSPYL2
Expression of Talin-1
Expression of WFS1
Expression of WIPI1
Expression of YIF1A
Expression of ZBTB17
Expression of DNAJC3 (p58IPK)