CHAT
UniProt:P28329 CHAT
PEMPT
PEMT
PNMT
UniProt:Q9UBM1 PEMT
CTL1-5 can mediate the uptake of choline
Cho transports from the extracellular space to the cytosol
Cho is acetylated to AcCho by CHAT
Synthesis of o-acetylcholine
AcCho is hydrolyzed to Cho and acetate by ACHE
Acetylcholine clearance from synaptic cleft
PA is dephosphorylated to DAG by LPIN
PE is methylated to PC by PEMT
Cho is phosphorylated to PCho by CHK dimer
PCho is dephosphorylated to Cho by PHOSPHO1
PCho and CTP are condensed to CDP-Cho by PCYT1 dimer
CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane
CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane
Synthesis of PC