Proteolytic processing of Slit
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0008233
BFO_0000050: Regulation of Commissural axon pathfinding by Slit and Robo

Robo3 antagonizes Robo1/Robo2 to allow floor plate crossing
type: GO_0003674
BFO_0000050: Regulation of Commissural axon pathfinding by Slit and Robo

Glypican-1 binds Slit2
type: GO_0003674
BFO_0000050: Signaling by Robo receptor
directly activates: Robo1 binds Slit2

Robo1 binds Slit2
type: GO_0003674
BFO_0000050: Signaling by Robo receptor
directly activates: Ena/VASP binds Robo1:Slit2 complex
directly activates: SrGAP binds Robo1:Slit2
directly activates: KIAA1688/Vilse binds Robo1:Slit2
directly activates: Nck binds Robo1:Slit2

Ena/VASP binds Robo1:Slit2 complex
type: GO_0003674
BFO_0000050: Signaling by Robo receptor
directly activates: Recruitment of Profilin by Ena/Vasp proteins

Recruitment of Profilin by Ena/Vasp proteins
type: GO_0003674
BFO_0000050: Signaling by Robo receptor

SrGAP binds Robo1:Slit2
type: GO_0003674
BFO_0000050: Inactivation of Cdc42 and Rac
directly activates: Inactivation of Rac1
directly activates: Catalysis3196

Inactivation of Cdc42
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0005096
BFO_0000050: Inactivation of Cdc42 and Rac

KIAA1688/Vilse binds Robo1:Slit2
type: GO_0003674
BFO_0000050: Inactivation of Cdc42 and Rac
directly activates: Inactivation of Cdc42
directly activates: Catalysis3195

Inactivation of Rac1
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0005096
BFO_0000050: Inactivation of Cdc42 and Rac

Nck binds Robo1:Slit2
type: GO_0003674
BFO_0000050: Activation of Rac
directly activates: Recruitment of PAK to Nck

Recruitment of PAK to Nck
type: GO_0003674
BFO_0000050: Activation of Rac
directly activates: Recruitment of Sos to plasma membrane

Recruitment of Sos to plasma membrane
type: GO_0003674
BFO_0000050: Activation of Rac
directly activates: Activation of Rac by Sos
directly activates: Catalysis3197

Activation of Rac by Sos
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0005088
BFO_0000050: Activation of Rac

Interaction of Abl with Robo1:Slit2
type: GO_0003674
BFO_0000050: Role of Abl in Robo-Slit signaling
directly activates: Phosphorylation of Rob1 by Abl kinase
directly activates: Activation of CLASP
directly activates: Recruitment of CAP to Abl
directly activates: Catalysis3198

Phosphorylation of Rob1 by Abl kinase
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0004713
BFO_0000050: Role of Abl in Robo-Slit signaling

Activation of CLASP
type: GO_0003674
BFO_0000050: Role of Abl in Robo-Slit signaling

Recruitment of CAP to Abl
type: GO_0003674
BFO_0000050: Role of Abl in Robo-Slit signaling

Signaling by Robo receptor
type: GO_0008150

Regulation of Commissural axon pathfinding by Slit and Robo
type: GO_0008150
BFO_0000050: Signaling by Robo receptor

Inactivation of Cdc42 and Rac
type: GO_0008150
BFO_0000050: Signaling by Robo receptor

Activation of Rac
type: GO_0008150
BFO_0000050: Signaling by Robo receptor

Role of Abl in Robo-Slit signaling
type: GO_0008150
BFO_0000050: Signaling by Robo receptor