Notch 3-ligand complex is cleaved to produce NEXT3
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0008237
BFO_0000050: Signaling by NOTCH3
directly activates: NEXT3 is cleaved to produce NICD3
directly activates: Catalysis1438

NEXT3 is cleaved to produce NICD3
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0004190
BFO_0000050: Signaling by NOTCH3
directly activates: NICD3 traffics to the nucleus

NICD3 traffics to the nucleus
type: GO_0003674
BFO_0000050: Signaling by NOTCH3

Notch 3 heterodimer binds with a Notch ligand in the extracellular space
type: GO_0003674
BFO_0000050: Signaling by NOTCH3
directly activates: Notch 3-ligand complex is cleaved to produce NEXT3
directly activates: Catalysis559

Signaling by NOTCH3
type: GO_0008150