DICER
DICER1
HERNA
KIAA0928
UniProt:Q9UPY3 DICER1
Microprocessor complex cleaves pri-miRNA to pre-miRNA
Exportin-5 recognizes 3' overhang of pre-miRNA
Exportin complex translocates pre-miRNA to cytosol
Dicer cleaves pre-miRNA to yield duplex miRNA
Duplex miRNA is loaded into Argonaute
Removal of miRNA passenger strand
Dicer cleaves double-stranded RNA to yield double-stranded siRNA
Duplex siRNA is loaded into Argonaute
Cleavage-based removal of the siRNA passenger strand by AGO2
Removal of siRNA passenger strand
Cleavage of Target RNAs by Endonucleolytic RISC
Binding of Inexactly Matching Target RNAs by RISC.
Binding of Exactly Matching Target RNAs by Nonendonucleolytic RISC
Regulatory RNA pathways
MicroRNA (miRNA) Biogenesis
Small Interfering RNA (siRNA) Biogenesis
Post-transcriptional Silencing By Small RNAs
Pol II mediated transcription of microRNA genes