AGM1
label: PGM3
label: UniProt:O95394 PGM3

GCNT3
label: UniProt:O95395 GCNT3

MCD4
label: PIGN
label: UniProt:O95427 PIGN

FUR
label: FURIN
label: PACE
label: PCSK3
label: UniProt:P09958 FURIN

SIAT1
label: ST6GAL1
label: UniProt:P15907 ST6GAL1

GGNT1
label: GLCT1
label: GLYT1
label: MGAT
label: MGAT1
label: UniProt:P26572 MGAT1

MPI
label: PMI1
label: UniProt:P34949 MPI

GC
label: GGCX
label: UniProt:P38435 GGCX

GGNT3
label: MGAT3
label: UniProt:Q09327 MGAT3

GGNT5
label: MGAT5
label: UniProt:Q09328 MGAT5

MGAT2
label: UniProt:Q10469 MGAT2

CGS23
label: NANTA3
label: SIAT4C
label: ST3GAL4
label: STZ
label: UniProt:Q11206 ST3GAL4

GCS1
label: MOGS
label: UniProt:Q13724 MOGS

ALG11
label: GT8
label: UniProt:Q2TAA5 ALG11

MANEA
label: UniProt:Q5SRI9 MANEA

PGAP1
label: UNQ3024/PRO9822
label: UniProt:Q75T13 PGAP1

PIGW
label: UniProt:Q7Z7B1 PIGW

DOLPP1
label: LSFR2
label: UniProt:Q86YN1 DOLPP1

FGE
label: PSEC0152
label: SUMF1
label: UNQ3037/PRO9852
label: UniProt:Q8NBK3 SUMF1

PIGB
label: UniProt:Q92521 PIGB

ALG3
label: NOT
label: NOT56L
label: UniProt:Q92685 ALG3

RFT1
label: UniProt:Q96AA3 RFT1

MSTP134
label: MSTP576
label: UNQ308/PRO351
label: UniProt:Q9BQB6 VKORC1
label: VKOR
label: VKORC1

ALG1
label: HMAT1
label: HMT1
label: PSEC0061
label: UNQ861/PRO1870
label: UniProt:Q9BT22 ALG1

ALG12
label: PP14673
label: UniProt:Q9BV10 ALG12

ALG8
label: HUSSY-02
label: UniProt:Q9BVK2 ALG8

FUT8
label: UniProt:Q9BYC5 FUT8

DPAGT1
label: DPAGT2
label: UniProt:Q9H3H5 DPAGT1

ALG2
label: UNQ666/PRO1298
label: UniProt:Q9H553 ALG2

ALG9
label: DIBD1
label: UniProt:Q9H6U8 ALG9

UniProt:Q9H9G5 cDNA FLJ12769 fis, clone NT2RP2001581
label: cDNA FLJ12769 fis, clone NT2RP2001581

PREB
label: SEC12
label: UniProt:Q9HCU5 PREB

PIGV
label: UniProt:Q9NUD9 PIGV

SIAT7B
label: SIATL1
label: ST6GALNAC2
label: STHM
label: UniProt:Q9UJ37 ST6GALNAC2

MAN1B1
label: UNQ747/PRO1477
label: UniProt:Q9UKM7 MAN1B1

DOLK
label: KIAA1094
label: TMEM15
label: UNQ2422/PRO4980
label: UniProt:Q9UPQ8 DOLK

PIGL
label: UniProt:Q9Y2B2 PIGL

ALG6
label: My046
label: UniProt:Q9Y672 ALG6

ALG5
label: HSPC149
label: UniProt:Q9Y673 ALG5

Sar1p Activation And Membrane Binding
type: Restriction
  on property: enabled by
  some values from: PREB
type: Restriction
  on property: enabled by
  some values from: PREB
type: Restriction
  on property: enabled by
  some values from: PREB
type: Restriction
  on property: enabled by
  some values from: PREB
type: Restriction
  on property: enabled by
  some values from: PREB
type: Restriction
  on property: enabled by
  some values from: PREB
type: Restriction
  on property: enabled by
  some values from: PREB
type: Restriction
  on property: enabled by
  some values from: PREB
type: Restriction
  on property: enabled by
  some values from: PREB
type: Restriction
  on property: enabled by
  some values from: PREB
type: Restriction
  on property: enabled by
  some values from: PREB
type: Restriction
  on property: enabled by
  some values from: PREB
type: Restriction
  on property: enabled by
  some values from: PREB
type: Restriction
  on property: enabled by
  some values from: PREB
type: Restriction
  on property: enabled by
  some values from: PREB
type: Restriction
  on property: enabled by
  some values from: PREB
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0005085
BFO_0000050: COPII (Coat Protein 2) Mediated Vesicle Transport

Coat Assembly
type: GO_0003674
BFO_0000050: COPII (Coat Protein 2) Mediated Vesicle Transport
directly activates: Loss of Sar1b GTPase
directly activates: Cargo, Sec31p:Sec13p, and v-SNARE recruitment
directly activates: BiochemicalReaction770
directly activates: Catalysis1446

Loss of Sar1b GTPase
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0003924
BFO_0000050: COPII (Coat Protein 2) Mediated Vesicle Transport
directly activates: Sar1p Activation And Membrane Binding
directly activates: Catalysis1445

Cargo, Sec31p:Sec13p, and v-SNARE recruitment
type: GO_0003674
BFO_0000050: COPII (Coat Protein 2) Mediated Vesicle Transport
directly activates: Vesicle Budding

Vesicle Budding
type: GO_0003674
BFO_0000050: COPII (Coat Protein 2) Mediated Vesicle Transport
directly activates: Vesicle Uncoating
directly activates: Catalysis1447

Vesicle Uncoating
type: Restriction
  on property: BFO_0000066
  some values from: GO_0012507
type: Restriction
  on property: BFO_0000066
  some values from: GO_0012507
type: Restriction
  on property: BFO_0000066
  some values from: GO_0012507
type: Restriction
  on property: BFO_0000066
  some values from: GO_0012507
type: Restriction
  on property: BFO_0000066
  some values from: GO_0012507
type: Restriction
  on property: BFO_0000066
  some values from: GO_0012507
type: Restriction
  on property: BFO_0000066
  some values from: GO_0012507
type: Restriction
  on property: BFO_0000066
  some values from: GO_0012507
type: Restriction
  on property: BFO_0000066
  some values from: GO_0012507
type: Restriction
  on property: BFO_0000066
  some values from: GO_0012507
type: Restriction
  on property: BFO_0000066
  some values from: GO_0012507
type: Restriction
  on property: BFO_0000066
  some values from: GO_0012507
type: Restriction
  on property: BFO_0000066
  some values from: GO_0012507
type: Restriction
  on property: BFO_0000066
  some values from: GO_0012507
type: Restriction
  on property: BFO_0000066
  some values from: GO_0012507
type: Restriction
  on property: BFO_0000066
  some values from: GO_0012507
type: GO_0003924
BFO_0000050: COPII (Coat Protein 2) Mediated Vesicle Transport

vitamin K epoxide -> vitamin K hydroquinone
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: enabled by
  some values from: MSTP134
type: Restriction
  on property: enabled by
  some values from: MSTP134
type: Restriction
  on property: enabled by
  some values from: MSTP134
type: Restriction
  on property: enabled by
  some values from: MSTP134
type: GO_0047057
BFO_0000050: Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
directly activates: pro-factor IX, uncarboxylated + 12 CO2 + 12 O2 + 12 vitamin K hydroquinone -> pro-factor IX + 12 H2O + 12 vitamin K epoxide
directly activates: pro-factor VII, uncarboxylated + 10 CO2 + 10 O2 + 10 vitamin K hydroquinone -> pro-factor VII + 10 H2O + 10 vitamin K epoxide
directly activates: pro-factor X, uncarboxylated + 11 CO2 + 11 O2 + 11 vitamin K hydroquinone -> pro-factor X + 11 H2O + 11 vitamin K epoxide
directly activates: pro-prothrombin, uncarboxylated + 10 CO2 + 10 O2 + 10 vitamin K hydroquinone -> pro-prothrombin + 10 H2O + 10 vitamin K epoxide
directly activates: pro-protein C, uncarboxylated + 8 CO2 + 8 O2 + 8 vitamin K hydroquinone -> pro-protein C + 8 H2O + 8 vitamin K epoxide
directly activates: pro-protein S, uncarboxylated + 11 CO2 + 11 O2 + 11 vitamin K hydroquinone -> pro-protein S + 11 H2O + 11 vitamin K epoxide
directly activates: pro-protein Z, uncarboxylated + 13 CO2 + 13 O2 + 13 vitamin K hydroquinone -> pro-protein Z + 13 H2O + 13 vitamin K epoxide
directly activates: pro-GAS6, uncarboxylated + 11 CO2 + 11 O2 + 11 vitamin K hydroquinone -> pro-GAS6 + 11 H2O + 11 vitamin K epoxide
directly activates: Catalysis1471
directly activates: Catalysis1472
directly activates: Catalysis1473
directly activates: Catalysis1474
directly activates: Catalysis1475
directly activates: Catalysis1476
directly activates: Catalysis1477
directly activates: Catalysis1478

pro-factor IX, uncarboxylated + 12 CO2 + 12 O2 + 12 vitamin K hydroquinone -> pro-factor IX + 12 H2O + 12 vitamin K epoxide
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: GO_0008488
BFO_0000050: Gamma-carboxylation of protein precursors
directly activates: vitamin K epoxide -> vitamin K hydroquinone
directly activates: Pro-factor IX is transported from the endoplasmic reticulum to the Golgi apparatus
directly activates: Catalysis1470

pro-factor VII, uncarboxylated + 10 CO2 + 10 O2 + 10 vitamin K hydroquinone -> pro-factor VII + 10 H2O + 10 vitamin K epoxide
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: GO_0008488
BFO_0000050: Gamma-carboxylation of protein precursors
directly activates: vitamin K epoxide -> vitamin K hydroquinone
directly activates: Pro-factor VII is transported from the endoplasmic reticulum to the Golgi apparatus
directly activates: Catalysis1470

pro-factor X, uncarboxylated + 11 CO2 + 11 O2 + 11 vitamin K hydroquinone -> pro-factor X + 11 H2O + 11 vitamin K epoxide
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: GO_0008488
BFO_0000050: Gamma-carboxylation of protein precursors
directly activates: vitamin K epoxide -> vitamin K hydroquinone
directly activates: Pro-factor X is transported from the endoplasmic reticulum to the Golgi apparatus
directly activates: Catalysis1470

pro-prothrombin, uncarboxylated + 10 CO2 + 10 O2 + 10 vitamin K hydroquinone -> pro-prothrombin + 10 H2O + 10 vitamin K epoxide
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: GO_0008488
BFO_0000050: Gamma-carboxylation of protein precursors
directly activates: vitamin K epoxide -> vitamin K hydroquinone
directly activates: Pro-prothrombin is transported from the endoplasmic reticulum to the Golgi apparatus
directly activates: Catalysis1470

pro-protein C, uncarboxylated + 8 CO2 + 8 O2 + 8 vitamin K hydroquinone -> pro-protein C + 8 H2O + 8 vitamin K epoxide
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: GO_0008488
BFO_0000050: Gamma-carboxylation of protein precursors
directly activates: vitamin K epoxide -> vitamin K hydroquinone
directly activates: Pro-protein C is transported from the endoplasmic reticulum to the Golgi apparatus
directly activates: Catalysis1470

pro-protein S, uncarboxylated + 11 CO2 + 11 O2 + 11 vitamin K hydroquinone -> pro-protein S + 11 H2O + 11 vitamin K epoxide
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: GO_0008488
BFO_0000050: Gamma-carboxylation of protein precursors
directly activates: vitamin K epoxide -> vitamin K hydroquinone
directly activates: Pro-protein S is transported from the endoplasmic reticulum to the Golgi apparatus
directly activates: Catalysis1470

pro-protein Z, uncarboxylated + 13 CO2 + 13 O2 + 13 vitamin K hydroquinone -> pro-protein Z + 13 H2O + 13 vitamin K epoxide
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: GO_0008488
BFO_0000050: Gamma-carboxylation of protein precursors
directly activates: vitamin K epoxide -> vitamin K hydroquinone
directly activates: Pro-protein Z is transported from the endoplasmic reticulum to the Golgi apparatus
directly activates: Catalysis1470

pro-GAS6, uncarboxylated + 11 CO2 + 11 O2 + 11 vitamin K hydroquinone -> pro-GAS6 + 11 H2O + 11 vitamin K epoxide
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: Restriction
  on property: enabled by
  some values from: GC
type: GO_0008488
BFO_0000050: Gamma-carboxylation of protein precursors
directly activates: vitamin K epoxide -> vitamin K hydroquinone
directly activates: Pro-GAS6 is transported from the endoplasmic reticulum to the Golgi apparatus
directly activates: Catalysis1470

Pro-factor IX is transported from the endoplasmic reticulum to the Golgi apparatus
type: GO_0003674
BFO_0000050: Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
directly activates: pro-factor IX -> factor IX + factor IX propeptide
directly activates: Catalysis1479

Pro-factor VII is transported from the endoplasmic reticulum to the Golgi apparatus
type: GO_0003674
BFO_0000050: Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
directly activates: pro-factor VII -> factor VII + factor VII propeptide
directly activates: Catalysis1480

Pro-factor X is transported from the endoplasmic reticulum to the Golgi apparatus
type: GO_0003674
BFO_0000050: Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
directly activates: pro-factor X -> factor X + factor X propeptide
directly activates: Catalysis1481

Pro-prothrombin is transported from the endoplasmic reticulum to the Golgi apparatus
type: GO_0003674
BFO_0000050: Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
directly activates: pro-prothrombin -> prothrombin + prothrombin propeptide
directly activates: Catalysis1482

Pro-protein C is transported from the endoplasmic reticulum to the Golgi apparatus
type: GO_0003674
BFO_0000050: Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
directly activates: pro-protein C -> protein C + protein C propeptide
directly activates: Catalysis1483

Pro-protein S is transported from the endoplasmic reticulum to the Golgi apparatus
type: GO_0003674
BFO_0000050: Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
directly activates: pro-protein S -> protein S + protein S propeptide
directly activates: Catalysis1484

Pro-protein Z is transported from the endoplasmic reticulum to the Golgi apparatus
type: GO_0003674
BFO_0000050: Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
directly activates: pro-protein Z -> protein Z + protein Z propeptide
directly activates: Catalysis1485

Pro-GAS6 is transported from the endoplasmic reticulum to the Golgi apparatus
type: GO_0003674
BFO_0000050: Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
directly activates: pro-GAS6 -> GAS6 + GAS6 propeptide
directly activates: Catalysis1486

pro-factor IX -> factor IX + factor IX propeptide
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: GO_0004252
BFO_0000050: Removal of aminoterminal propeptides from gamma-carboxylated proteins

pro-factor VII -> factor VII + factor VII propeptide
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: GO_0004252
BFO_0000050: Removal of aminoterminal propeptides from gamma-carboxylated proteins

pro-factor X -> factor X + factor X propeptide
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: GO_0004252
BFO_0000050: Removal of aminoterminal propeptides from gamma-carboxylated proteins

pro-prothrombin -> prothrombin + prothrombin propeptide
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: GO_0004252
BFO_0000050: Removal of aminoterminal propeptides from gamma-carboxylated proteins

pro-protein C -> protein C + protein C propeptide
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: GO_0004252
BFO_0000050: Removal of aminoterminal propeptides from gamma-carboxylated proteins

pro-protein S -> protein S + protein S propeptide
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: GO_0004252
BFO_0000050: Removal of aminoterminal propeptides from gamma-carboxylated proteins

pro-protein Z -> protein Z + protein Z propeptide
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: enabled by
  some values from: FUR
type: GO_0004252
BFO_0000050: Removal of aminoterminal propeptides from gamma-carboxylated proteins

pro-GAS6 -> GAS6 + GAS6 propeptide
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: enabled by
  some values from: FUR
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: GO_0004252
BFO_0000050: Removal of aminoterminal propeptides from gamma-carboxylated proteins

EIF5A + spermidine <=> EIF5A(Dhp) + 1,3-diaminopropane
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0034038
BFO_0000050: Hypusine synthesis from eIF5A-lysine
directly activates: EIF5A(Dhp) + O2 => EIF5A(Hyp)
directly activates: Catalysis1489

EIF5A(Dhp) + 1,3-diaminopropane <=> EIF5A + spermidine
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0034038
BFO_0000050: Hypusine synthesis from eIF5A-lysine

EIF5A(Dhp) + O2 => EIF5A(Hyp)
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0019135
BFO_0000050: Hypusine synthesis from eIF5A-lysine

SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: enabled by
  some values from: FGE
type: Restriction
  on property: enabled by
  some values from: FGE
type: Restriction
  on property: enabled by
  some values from: FGE
type: Restriction
  on property: enabled by
  some values from: FGE
type: GO_0016491
BFO_0000050: The activation of arylsulfatases
directly activates: BiochemicalReaction5296

SUMF2 inhibits SUMF1-mediated activation of arylsulfatases
type: GO_0003674
BFO_0000050: The activation of arylsulfatases

dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0004582
BFO_0000050: Synthesis of dolichyl-phosphate mannose
directly activates: Reorientation of dolichyl phosphate D-mannose in the endoplasmic reticulum membrane

Reorientation of dolichyl phosphate D-mannose in the endoplasmic reticulum membrane
type: GO_0003674
BFO_0000050: Synthesis of dolichyl-phosphate mannose
directly activates: glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate
directly activates: (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate
directly activates: BiochemicalReaction3508
directly activates: Catalysis1495
directly activates: Catalysis1497
directly activates: Catalysis1498

phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0008194
BFO_0000050: Synthesis of glycosylphosphatidylinositol (GPI)
directly activates: N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate
directly activates: Catalysis1493

N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate
type: Restriction
  on property: enabled by
  some values from: PIGL
type: Restriction
  on property: enabled by
  some values from: PIGL
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: enabled by
  some values from: PIGL
type: Restriction
  on property: enabled by
  some values from: PIGL
type: GO_0000225
BFO_0000050: Synthesis of glycosylphosphatidylinositol (GPI)
directly activates: Reorientation of glucosaminyl-acyl-PI in the endoplasmic reticulum membrane

Reorientation of glucosaminyl-acyl-PI in the endoplasmic reticulum membrane
type: GO_0003674
BFO_0000050: Synthesis of glycosylphosphatidylinositol (GPI)
directly activates: glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH
directly activates: Catalysis1494

glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH
type: Restriction
  on property: enabled by
  some values from: PIGW
type: Restriction
  on property: enabled by
  some values from: PIGW
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: enabled by
  some values from: PIGW
type: Restriction
  on property: enabled by
  some values from: PIGW
type: GO_0008374
BFO_0000050: Synthesis of glycosylphosphatidylinositol (GPI)
directly activates: glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate
directly activates: Catalysis1495

glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0000030
BFO_0000050: Synthesis of glycosylphosphatidylinositol (GPI)
directly activates: mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol
directly activates: Catalysis1496

mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol
type: Restriction
  on property: enabled by
  some values from: MCD4
type: Restriction
  on property: enabled by
  some values from: MCD4
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: enabled by
  some values from: MCD4
type: Restriction
  on property: enabled by
  some values from: MCD4
type: GO_0016780
BFO_0000050: Synthesis of glycosylphosphatidylinositol (GPI)
directly activates: (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate
directly activates: Catalysis1497

(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate
type: Restriction
  on property: enabled by
  some values from: PIGV
type: Restriction
  on property: enabled by
  some values from: PIGV
type: Restriction
  on property: enabled by
  some values from: PIGV
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: enabled by
  some values from: PIGV
type: GO_0004376
BFO_0000050: Synthesis of glycosylphosphatidylinositol (GPI)
directly activates: BiochemicalReaction3508
directly activates: Catalysis1498

BiochemicalReaction3508
type: Restriction
  on property: enabled by
  some values from: PIGB
type: Restriction
  on property: enabled by
  some values from: PIGB
type: Restriction
  on property: enabled by
  some values from: PIGB
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: enabled by
  some values from: PIGB
type: GO_0004376
BFO_0000050: Synthesis of glycosylphosphatidylinositol (GPI)
directly activates: BiochemicalReaction3509
directly activates: mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI
directly activates: Catalysis1499
directly activates: Catalysis1500
label: mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate

BiochemicalReaction3509
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0016780
BFO_0000050: Synthesis of glycosylphosphatidylinositol (GPI)
directly activates: BiochemicalReaction3511
directly activates: uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide
directly activates: Catalysis1501
directly activates: Catalysis1502
label: mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (acyl-GPI) + diacylglycerol

mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI
type: Restriction
  on property: enabled by
  some values from: UniProt:Q9H9G5 cDNA FLJ12769 fis, clone NT2RP2001581
type: Restriction
  on property: enabled by
  some values from: UniProt:Q9H9G5 cDNA FLJ12769 fis, clone NT2RP2001581
type: Restriction
  on property: enabled by
  some values from: UniProt:Q9H9G5 cDNA FLJ12769 fis, clone NT2RP2001581
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: enabled by
  some values from: UniProt:Q9H9G5 cDNA FLJ12769 fis, clone NT2RP2001581
type: GO_0000030
BFO_0000050: Synthesis of glycosylphosphatidylinositol (GPI)

BiochemicalReaction3511
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0016780
BFO_0000050: Synthesis of glycosylphosphatidylinositol (GPI)
label: (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> (ethanolamineP) mannose (a1-2) (ethanolamineP) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI

uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0003923
BFO_0000050: Attachment of GPI anchor to uPAR
directly activates: uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid
directly activates: Catalysis1503

uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid
type: Restriction
  on property: enabled by
  some values from: PGAP1
type: Restriction
  on property: enabled by
  some values from: PGAP1
type: Restriction
  on property: enabled by
  some values from: PGAP1
type: Restriction
  on property: enabled by
  some values from: PGAP1
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0016788
BFO_0000050: Attachment of GPI anchor to uPAR

Phosphorylation of dolichol
type: Restriction
  on property: enabled by
  some values from: DOLK
type: Restriction
  on property: enabled by
  some values from: DOLK
type: Restriction
  on property: enabled by
  some values from: DOLK
type: Restriction
  on property: enabled by
  some values from: DOLK
type: Restriction
  on property: enabled by
  some values from: DOLK
type: Restriction
  on property: enabled by
  some values from: DOLK
type: Restriction
  on property: enabled by
  some values from: DOLK
type: Restriction
  on property: enabled by
  some values from: DOLK
type: Restriction
  on property: enabled by
  some values from: DOLK
type: Restriction
  on property: enabled by
  some values from: DOLK
type: Restriction
  on property: enabled by
  some values from: DOLK
type: Restriction
  on property: enabled by
  some values from: DOLK
type: Restriction
  on property: enabled by
  some values from: DOLK
type: Restriction
  on property: enabled by
  some values from: DOLK
type: Restriction
  on property: enabled by
  some values from: DOLK
type: Restriction
  on property: enabled by
  some values from: DOLK
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0004168
BFO_0000050: Synthesis of Dolichyl-phosphate
directly activates: Addition of N-acetyl-D-glucosamine to Dolichyl phosphate
directly activates: Catalysis1514

Dephosphorylation of dolichyl diphosphate
type: Restriction
  on property: enabled by
  some values from: DOLPP1
type: Restriction
  on property: enabled by
  some values from: DOLPP1
type: Restriction
  on property: enabled by
  some values from: DOLPP1
type: Restriction
  on property: enabled by
  some values from: DOLPP1
type: Restriction
  on property: enabled by
  some values from: DOLPP1
type: Restriction
  on property: enabled by
  some values from: DOLPP1
type: Restriction
  on property: enabled by
  some values from: DOLPP1
type: Restriction
  on property: enabled by
  some values from: DOLPP1
type: Restriction
  on property: enabled by
  some values from: DOLPP1
type: Restriction
  on property: enabled by
  some values from: DOLPP1
type: Restriction
  on property: enabled by
  some values from: DOLPP1
type: Restriction
  on property: enabled by
  some values from: DOLPP1
type: Restriction
  on property: enabled by
  some values from: DOLPP1
type: Restriction
  on property: enabled by
  some values from: DOLPP1
type: Restriction
  on property: enabled by
  some values from: DOLPP1
type: Restriction
  on property: enabled by
  some values from: DOLPP1
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0047874
BFO_0000050: Synthesis of Dolichyl-phosphate
directly activates: Addition of N-acetyl-D-glucosamine to Dolichyl phosphate
directly activates: Catalysis1514

Formation of glucosamine 6-phosphate from fructose 6-phosphate and glutamine
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004360
BFO_0000050: Synthesis of UDP-N-acetyl-glucosamine
directly activates: Acetylation of glucosamine 6-phosphate to GlcNAc6P
directly activates: Catalysis1507

Acetylation of glucosamine 6-phosphate to GlcNAc6P
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004343
BFO_0000050: Synthesis of UDP-N-acetyl-glucosamine
directly activates: Isomerization of GlcNAc6P to GlcNAc1P
directly activates: Catalysis1508

Isomerization of GlcNAc6P to GlcNAc1P
type: Restriction
  on property: enabled by
  some values from: AGM1
type: Restriction
  on property: enabled by
  some values from: AGM1
type: Restriction
  on property: enabled by
  some values from: AGM1
type: Restriction
  on property: enabled by
  some values from: AGM1
type: Restriction
  on property: enabled by
  some values from: AGM1
type: Restriction
  on property: enabled by
  some values from: AGM1
type: Restriction
  on property: enabled by
  some values from: AGM1
type: Restriction
  on property: enabled by
  some values from: AGM1
type: Restriction
  on property: enabled by
  some values from: AGM1
type: Restriction
  on property: enabled by
  some values from: AGM1
type: Restriction
  on property: enabled by
  some values from: AGM1
type: Restriction
  on property: enabled by
  some values from: AGM1
type: Restriction
  on property: enabled by
  some values from: AGM1
type: Restriction
  on property: enabled by
  some values from: AGM1
type: Restriction
  on property: enabled by
  some values from: AGM1
type: Restriction
  on property: enabled by
  some values from: AGM1
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004610
BFO_0000050: Synthesis of UDP-N-acetyl-glucosamine
directly activates: GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine
directly activates: Catalysis1509

GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0003977
BFO_0000050: Synthesis of UDP-N-acetyl-glucosamine
directly activates: Addition of N-acetyl-D-glucosamine to Dolichyl phosphate
directly activates: Catalysis1514

Fructose 6-phosphate isomerizes to Mannose 6-phosphate
type: Restriction
  on property: enabled by
  some values from: MPI
type: Restriction
  on property: enabled by
  some values from: MPI
type: Restriction
  on property: enabled by
  some values from: MPI
type: Restriction
  on property: enabled by
  some values from: MPI
type: Restriction
  on property: enabled by
  some values from: MPI
type: Restriction
  on property: enabled by
  some values from: MPI
type: Restriction
  on property: enabled by
  some values from: MPI
type: Restriction
  on property: enabled by
  some values from: MPI
type: Restriction
  on property: enabled by
  some values from: MPI
type: Restriction
  on property: enabled by
  some values from: MPI
type: Restriction
  on property: enabled by
  some values from: MPI
type: Restriction
  on property: enabled by
  some values from: MPI
type: Restriction
  on property: enabled by
  some values from: MPI
type: Restriction
  on property: enabled by
  some values from: MPI
type: Restriction
  on property: enabled by
  some values from: MPI
type: Restriction
  on property: enabled by
  some values from: MPI
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004476
BFO_0000050: Synthesis of GDP-mannose

Mannose 6-phosphate isomerizes to Mannose 1-phosphate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004615
BFO_0000050: Synthesis of GDP-mannose
directly activates: Mannose-1-phosphate converted to GDP-Mannose
directly activates: Catalysis1512

Mannose-1-phosphate converted to GDP-Mannose
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004475
BFO_0000050: Synthesis of GDP-mannose

Synthesis of dolichyl-phosphate-glucose
type: Restriction
  on property: enabled by
  some values from: ALG5
type: Restriction
  on property: enabled by
  some values from: ALG5
type: Restriction
  on property: enabled by
  some values from: ALG5
type: Restriction
  on property: enabled by
  some values from: ALG5
type: Restriction
  on property: enabled by
  some values from: ALG5
type: Restriction
  on property: enabled by
  some values from: ALG5
type: Restriction
  on property: enabled by
  some values from: ALG5
type: Restriction
  on property: enabled by
  some values from: ALG5
type: Restriction
  on property: enabled by
  some values from: ALG5
type: Restriction
  on property: enabled by
  some values from: ALG5
type: Restriction
  on property: enabled by
  some values from: ALG5
type: Restriction
  on property: enabled by
  some values from: ALG5
type: Restriction
  on property: enabled by
  some values from: ALG5
type: Restriction
  on property: enabled by
  some values from: ALG5
type: Restriction
  on property: enabled by
  some values from: ALG5
type: Restriction
  on property: enabled by
  some values from: ALG5
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0004581
BFO_0000050: Synthesis of dolichyl-phosphate-glucose
directly activates: Flipping of dolichyl-phosphate-glucose into the ER lumen

Flipping of dolichyl-phosphate-glucose into the ER lumen
type: GO_0003674
BFO_0000050: Synthesis of dolichyl-phosphate-glucose

Addition of N-acetyl-D-glucosamine to Dolichyl phosphate
type: Restriction
  on property: enabled by
  some values from: DPAGT1
type: Restriction
  on property: enabled by
  some values from: DPAGT1
type: Restriction
  on property: enabled by
  some values from: DPAGT1
type: Restriction
  on property: enabled by
  some values from: DPAGT1
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0003975
BFO_0000050: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
directly activates: Addition of the second N-acetyl-glucosamine to the N-glycan precursor
directly activates: Catalysis1515

Addition of the second N-acetyl-glucosamine to the N-glycan precursor
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0004577
BFO_0000050: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
directly activates: Addition of the first mannose to the N-glycan precursor by ALG13/14
directly activates: Catalysis1516

Addition of the first mannose to the N-glycan precursor by ALG13/14
type: Restriction
  on property: enabled by
  some values from: ALG1
type: Restriction
  on property: enabled by
  some values from: ALG1
type: Restriction
  on property: enabled by
  some values from: ALG1
type: Restriction
  on property: enabled by
  some values from: ALG1
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0004578
BFO_0000050: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
directly activates: Addition of a second mannose to the N-glycan precursor by ALG2
directly activates: Catalysis1517

Addition of a second mannose to the N-glycan precursor by ALG2
type: Restriction
  on property: enabled by
  some values from: ALG2
type: Restriction
  on property: enabled by
  some values from: ALG2
type: Restriction
  on property: enabled by
  some values from: ALG2
type: Restriction
  on property: enabled by
  some values from: ALG2
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0000033
BFO_0000050: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
directly activates: Addition of a third mannose to the N-glycan precursor by ALG2
directly activates: Catalysis1518

Addition of a third mannose to the N-glycan precursor by ALG2
type: Restriction
  on property: enabled by
  some values from: ALG2
type: Restriction
  on property: enabled by
  some values from: ALG2
type: Restriction
  on property: enabled by
  some values from: ALG2
type: Restriction
  on property: enabled by
  some values from: ALG2
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0000009
BFO_0000050: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
directly activates: Addition of a fourth and fifth mannose to the N-glycan precursor by ALG11
directly activates: Catalysis1519

Addition of a fourth and fifth mannose to the N-glycan precursor by ALG11
type: Restriction
  on property: enabled by
  some values from: ALG11
type: Restriction
  on property: enabled by
  some values from: ALG11
type: Restriction
  on property: enabled by
  some values from: ALG11
type: Restriction
  on property: enabled by
  some values from: ALG11
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0000026
BFO_0000050: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
directly activates: Flipping of the N-glycan precursor to inside the ER
directly activates: Catalysis1520

Flipping of the N-glycan precursor to inside the ER
type: Restriction
  on property: enabled by
  some values from: RFT1
type: Restriction
  on property: enabled by
  some values from: RFT1
type: Restriction
  on property: enabled by
  some values from: RFT1
type: Restriction
  on property: enabled by
  some values from: RFT1
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0034202
BFO_0000050: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
directly activates: Addition of the sixth mannose to the N-glycan precursor by ALG3.
directly activates: Catalysis1521

Addition of the sixth mannose to the N-glycan precursor by ALG3.
type: Restriction
  on property: enabled by
  some values from: ALG3
type: Restriction
  on property: enabled by
  some values from: ALG3
type: Restriction
  on property: enabled by
  some values from: ALG3
type: Restriction
  on property: enabled by
  some values from: ALG3
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0000033
BFO_0000050: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
directly activates: Addition of the seventh mannose to the N-glycan precursor by ALG9, inside the ER lumen
directly activates: Catalysis1522

Addition of the seventh mannose to the N-glycan precursor by ALG9, inside the ER lumen
type: Restriction
  on property: enabled by
  some values from: ALG9
type: Restriction
  on property: enabled by
  some values from: ALG9
type: Restriction
  on property: enabled by
  some values from: ALG9
type: Restriction
  on property: enabled by
  some values from: ALG9
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0000026
BFO_0000050: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
directly activates: Addition of the eighth mannose to the N-glycan precursor by ALG12, inside the ER lumen
directly activates: Catalysis1523

Addition of the eighth mannose to the N-glycan precursor by ALG12, inside the ER lumen
type: Restriction
  on property: enabled by
  some values from: ALG12
type: Restriction
  on property: enabled by
  some values from: ALG12
type: Restriction
  on property: enabled by
  some values from: ALG12
type: Restriction
  on property: enabled by
  some values from: ALG12
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0000030
BFO_0000050: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
directly activates: Addition of the last mannose to the N-glycan precursor by ALG3, inside the ER lumen.
directly activates: Catalysis1524

Addition of the last mannose to the N-glycan precursor by ALG3, inside the ER lumen.
type: Restriction
  on property: enabled by
  some values from: ALG9
type: Restriction
  on property: enabled by
  some values from: ALG9
type: Restriction
  on property: enabled by
  some values from: ALG9
type: Restriction
  on property: enabled by
  some values from: ALG9
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0000026
BFO_0000050: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
directly activates: Addition of the first glucose to the N-glycan precursor by ALG6
directly activates: Catalysis1525

Addition of the first glucose to the N-glycan precursor by ALG6
type: Restriction
  on property: enabled by
  some values from: ALG6
type: Restriction
  on property: enabled by
  some values from: ALG6
type: Restriction
  on property: enabled by
  some values from: ALG6
type: Restriction
  on property: enabled by
  some values from: ALG6
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0004583
BFO_0000050: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
directly activates: Addition of a second glucose to the N-glycan precursor by ALG8
directly activates: Catalysis1526

Addition of a second glucose to the N-glycan precursor by ALG8
type: Restriction
  on property: enabled by
  some values from: ALG8
type: Restriction
  on property: enabled by
  some values from: ALG8
type: Restriction
  on property: enabled by
  some values from: ALG8
type: Restriction
  on property: enabled by
  some values from: ALG8
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0004583
BFO_0000050: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
directly activates: Addition of a third glucose to the N-glycan precursor by an ALG10 homologue
directly activates: Catalysis1527

Addition of a third glucose to the N-glycan precursor by an ALG10 homologue
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0004583
BFO_0000050: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein

Transfer of N-glycan to the protein
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0004579
BFO_0000050: Asparagine N-linked glycosylation
directly activates: Trimming of the first glucose by glucosidase I
directly activates: Catalysis1529

Trimming of the first glucose by glucosidase I
type: Restriction
  on property: enabled by
  some values from: GCS1
type: Restriction
  on property: enabled by
  some values from: GCS1
type: Restriction
  on property: enabled by
  some values from: GCS1
type: Restriction
  on property: enabled by
  some values from: GCS1
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0004573
BFO_0000050: N-glycan trimming in the ER and Calnexin/Calreticulin cycle
directly activates: Binding of Malectin

Binding of Malectin
type: GO_0003674
BFO_0000050: N-glycan trimming in the ER and Calnexin/Calreticulin cycle
directly activates: Removal of the second glucose by glucosidase II
directly activates: Catalysis1530

Removal of the second glucose by glucosidase II
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: GO_0033919
BFO_0000050: N-glycan trimming in the ER and Calnexin/Calreticulin cycle
directly activates: Binding of calnexin/calreticulin to the unfolded protein

Binding of calnexin/calreticulin to the unfolded protein
type: GO_0003674
BFO_0000050: Calnexin/calreticulin cycle
directly activates: Binding of ERp57

Binding of ERp57
type: GO_0003674
BFO_0000050: Calnexin/calreticulin cycle
directly activates: Removal of the third glucose by glucosidase II and release from the chaperone
directly activates: Catalysis1531

Removal of the third glucose by glucosidase II and release from the chaperone
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: GO_0033919
BFO_0000050: Calnexin/calreticulin cycle
directly activates: Incorrectly folded glycoproteins translocate to the ERQC
directly activates: Correctly folded glycoproteins translocate to the Golgi

Incorrectly folded glycoproteins translocate to the ERQC
type: GO_0003674
BFO_0000050: Calnexin/calreticulin cycle
directly activates: Trimming of the terminal mannose on the B branch
directly activates: Catalysis1532

Trimming of the terminal mannose on the B branch
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: GO_0004559
BFO_0000050: ER Quality Control Compartment (ERQC)
directly activates: Transport of glycoproteins with Man8 (or Man9) N-glycans to the Golgi
directly activates: Catalysis1538

Trimming of the terminal mannose on the C branch
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: GO_0004559
BFO_0000050: ER Quality Control Compartment (ERQC)
directly activates: Transport of glycoproteins with Man8 (or Man9) N-glycans to the Golgi
directly activates: Catalysis1538

Trimming of the first mannose on the A branch
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: GO_0004559
BFO_0000050: ER Quality Control Compartment (ERQC)
directly activates: Trimming of the second mannose on the A branch
directly activates: Glycoproteins with major folding defects are sent to degradation by EDEMs
directly activates: Transport of glycoproteins with Man8 (or Man9) N-glycans to the Golgi
directly activates: Catalysis1535
directly activates: Catalysis1537
directly activates: Catalysis1538

Trimming of the second mannose on the A branch
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: enabled by
  some values from: MAN1B1
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: Restriction
  on property: BFO_0000066
  some values from: GO_0044322
type: GO_0004559
BFO_0000050: ER Quality Control Compartment (ERQC)
directly activates: Glycoproteins with major folding defects are sent to degradation by EDEMs
directly activates: Catalysis1537

Re-addition of a glucose on the alpha 1,3 branch
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005788
type: GO_0003980
BFO_0000050: ER Quality Control Compartment (ERQC)
directly activates: Glycoproteins with lesser folding defects get transported back to the ER and the CNX/CRT complex

Glycoproteins with major folding defects are sent to degradation by EDEMs
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0051787
BFO_0000050: ER Quality Control Compartment (ERQC)

Glycoproteins with lesser folding defects get transported back to the ER and the CNX/CRT complex
type: GO_0003674
BFO_0000050: ER Quality Control Compartment (ERQC)
directly activates: Binding of calnexin/calreticulin to the unfolded protein

Correctly folded glycoproteins translocate to the Golgi
type: GO_0003674
BFO_0000050: Transport to the Golgi and subsequent modification

Transport of glycoproteins with Man8 (or Man9) N-glycans to the Golgi
type: Restriction
  on property: BFO_0000066
  some values from: GO_0012507
type: Restriction
  on property: BFO_0000066
  some values from: GO_0012507
type: Restriction
  on property: BFO_0000066
  some values from: GO_0012507
type: Restriction
  on property: BFO_0000066
  some values from: GO_0012507
type: GO_0005537
BFO_0000050: Transport to the Golgi and subsequent modification

Alternative endo-mannosidase I route
type: Restriction
  on property: enabled by
  some values from: MANEA
type: Restriction
  on property: enabled by
  some values from: MANEA
type: Restriction
  on property: enabled by
  some values from: MANEA
type: Restriction
  on property: enabled by
  some values from: MANEA
type: Restriction
  on property: enabled by
  some values from: MANEA
type: Restriction
  on property: enabled by
  some values from: MANEA
type: Restriction
  on property: enabled by
  some values from: MANEA
type: Restriction
  on property: enabled by
  some values from: MANEA
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: GO_0004569
BFO_0000050: N-glycan trimming and elongation in the cis-Golgi

Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: GO_0004571
BFO_0000050: Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2
directly activates: Addition of GlcNAc to the glycan on the A arm
directly activates: Catalysis1543

Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: GO_0004571
BFO_0000050: Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2
directly activates: Addition of GlcNAc to the glycan on the A arm
directly activates: Catalysis1543

Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: GO_0004571
BFO_0000050: Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2
directly activates: Addition of GlcNAc to the glycan on the A arm
directly activates: Catalysis1543

Addition of GlcNAc to the glycan on the A arm
type: Restriction
  on property: enabled by
  some values from: GGNT1
type: Restriction
  on property: enabled by
  some values from: GGNT1
type: Restriction
  on property: enabled by
  some values from: GGNT1
type: Restriction
  on property: enabled by
  some values from: GGNT1
type: Restriction
  on property: enabled by
  some values from: GGNT1
type: Restriction
  on property: enabled by
  some values from: GGNT1
type: Restriction
  on property: enabled by
  some values from: GGNT1
type: Restriction
  on property: enabled by
  some values from: GGNT1
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: GO_0003827
BFO_0000050: N-glycan trimming and elongation in the cis-Golgi

Addition of a bifurcating GlcNAc to the N-glycan by MGAT3
type: Restriction
  on property: enabled by
  some values from: GGNT3
type: Restriction
  on property: enabled by
  some values from: GGNT3
type: Restriction
  on property: enabled by
  some values from: GGNT3
type: Restriction
  on property: enabled by
  some values from: GGNT3
type: Restriction
  on property: enabled by
  some values from: GGNT3
type: Restriction
  on property: enabled by
  some values from: GGNT3
type: Restriction
  on property: enabled by
  some values from: GGNT3
type: Restriction
  on property: enabled by
  some values from: GGNT3
type: Restriction
  on property: enabled by
  some values from: GGNT3
type: Restriction
  on property: enabled by
  some values from: GGNT3
type: Restriction
  on property: enabled by
  some values from: GGNT3
type: Restriction
  on property: enabled by
  some values from: GGNT3
type: Restriction
  on property: enabled by
  some values from: GGNT3
type: Restriction
  on property: enabled by
  some values from: GGNT3
type: Restriction
  on property: enabled by
  some values from: GGNT3
type: Restriction
  on property: enabled by
  some values from: GGNT3
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: GO_0003830
BFO_0000050: Reactions specific to the hybrid N-glycan synthesis pathway

Trimming of mannoses on the alpha1,6 arm by MAN2A1
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: GO_0004572
BFO_0000050: Reactions specific to the complex N-glycan synthesis pathway
directly activates: Addition of a GlcNAc on the alpha 1,4 branch by MGAT2
directly activates: Catalysis1546

Addition of a GlcNAc on the alpha 1,4 branch by MGAT2
type: Restriction
  on property: enabled by
  some values from: MGAT2
type: Restriction
  on property: enabled by
  some values from: MGAT2
type: Restriction
  on property: enabled by
  some values from: MGAT2
type: Restriction
  on property: enabled by
  some values from: MGAT2
type: Restriction
  on property: enabled by
  some values from: MGAT2
type: Restriction
  on property: enabled by
  some values from: MGAT2
type: Restriction
  on property: enabled by
  some values from: MGAT2
type: Restriction
  on property: enabled by
  some values from: MGAT2
type: Restriction
  on property: enabled by
  some values from: MGAT2
type: Restriction
  on property: enabled by
  some values from: MGAT2
type: Restriction
  on property: enabled by
  some values from: MGAT2
type: Restriction
  on property: enabled by
  some values from: MGAT2
type: Restriction
  on property: enabled by
  some values from: MGAT2
type: Restriction
  on property: enabled by
  some values from: MGAT2
type: Restriction
  on property: enabled by
  some values from: MGAT2
type: Restriction
  on property: enabled by
  some values from: MGAT2
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: GO_0008455
BFO_0000050: Reactions specific to the complex N-glycan synthesis pathway

Addition of alpha 1,6 fucose to the first GlcNAc of the N-glycan
type: Restriction
  on property: enabled by
  some values from: FUT8
type: Restriction
  on property: enabled by
  some values from: FUT8
type: Restriction
  on property: enabled by
  some values from: FUT8
type: Restriction
  on property: enabled by
  some values from: FUT8
type: Restriction
  on property: enabled by
  some values from: FUT8
type: Restriction
  on property: enabled by
  some values from: FUT8
type: Restriction
  on property: enabled by
  some values from: FUT8
type: Restriction
  on property: enabled by
  some values from: FUT8
type: Restriction
  on property: enabled by
  some values from: FUT8
type: Restriction
  on property: enabled by
  some values from: FUT8
type: Restriction
  on property: enabled by
  some values from: FUT8
type: Restriction
  on property: enabled by
  some values from: FUT8
type: Restriction
  on property: enabled by
  some values from: FUT8
type: Restriction
  on property: enabled by
  some values from: FUT8
type: Restriction
  on property: enabled by
  some values from: FUT8
type: Restriction
  on property: enabled by
  some values from: FUT8
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: GO_0008424
BFO_0000050: Reactions specific to the complex N-glycan synthesis pathway

Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: GO_0008454
BFO_0000050: N-Glycan antennae elongation

Addition of GlcNAc to position 5 by MGAT5
type: Restriction
  on property: enabled by
  some values from: GGNT5
type: Restriction
  on property: enabled by
  some values from: GGNT5
type: Restriction
  on property: enabled by
  some values from: GGNT5
type: Restriction
  on property: enabled by
  some values from: GGNT5
type: Restriction
  on property: enabled by
  some values from: GGNT5
type: Restriction
  on property: enabled by
  some values from: GGNT5
type: Restriction
  on property: enabled by
  some values from: GGNT5
type: Restriction
  on property: enabled by
  some values from: GGNT5
type: Restriction
  on property: enabled by
  some values from: GGNT5
type: Restriction
  on property: enabled by
  some values from: GGNT5
type: Restriction
  on property: enabled by
  some values from: GGNT5
type: Restriction
  on property: enabled by
  some values from: GGNT5
type: Restriction
  on property: enabled by
  some values from: GGNT5
type: Restriction
  on property: enabled by
  some values from: GGNT5
type: Restriction
  on property: enabled by
  some values from: GGNT5
type: Restriction
  on property: enabled by
  some values from: GGNT5
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: GO_0030144
BFO_0000050: N-Glycan antennae elongation

Addition of galactose by beta 4-galactosyltransferases
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: GO_0003831
BFO_0000050: N-Glycan antennae elongation

Addition of alpha-2,6-sialic acid to terminal galactose of N-glycans by ST6GAL1
type: Restriction
  on property: enabled by
  some values from: SIAT1
type: Restriction
  on property: enabled by
  some values from: SIAT1
type: Restriction
  on property: enabled by
  some values from: SIAT1
type: Restriction
  on property: enabled by
  some values from: SIAT1
type: Restriction
  on property: enabled by
  some values from: SIAT1
type: Restriction
  on property: enabled by
  some values from: SIAT1
type: Restriction
  on property: enabled by
  some values from: SIAT1
type: Restriction
  on property: enabled by
  some values from: SIAT1
type: Restriction
  on property: enabled by
  some values from: SIAT1
type: Restriction
  on property: enabled by
  some values from: SIAT1
type: Restriction
  on property: enabled by
  some values from: SIAT1
type: Restriction
  on property: enabled by
  some values from: SIAT1
type: Restriction
  on property: enabled by
  some values from: SIAT1
type: Restriction
  on property: enabled by
  some values from: SIAT1
type: Restriction
  on property: enabled by
  some values from: SIAT1
type: Restriction
  on property: enabled by
  some values from: SIAT1
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: GO_0003835
BFO_0000050: N-Glycan antennae elongation

Addition of alpha-2,8-sialic acid to N-glycan over a galactose by ST8SIAs
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: GO_0003828
BFO_0000050: N-Glycan antennae elongation

Addition of alpha-2,3-sialic acid to N-glycan over a galactose by ST3GAL4
type: Restriction
  on property: enabled by
  some values from: CGS23
type: Restriction
  on property: enabled by
  some values from: CGS23
type: Restriction
  on property: enabled by
  some values from: CGS23
type: Restriction
  on property: enabled by
  some values from: CGS23
type: Restriction
  on property: enabled by
  some values from: CGS23
type: Restriction
  on property: enabled by
  some values from: CGS23
type: Restriction
  on property: enabled by
  some values from: CGS23
type: Restriction
  on property: enabled by
  some values from: CGS23
type: Restriction
  on property: enabled by
  some values from: CGS23
type: Restriction
  on property: enabled by
  some values from: CGS23
type: Restriction
  on property: enabled by
  some values from: CGS23
type: Restriction
  on property: enabled by
  some values from: CGS23
type: Restriction
  on property: enabled by
  some values from: CGS23
type: Restriction
  on property: enabled by
  some values from: CGS23
type: Restriction
  on property: enabled by
  some values from: CGS23
type: Restriction
  on property: enabled by
  some values from: CGS23
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: GO_0003836
BFO_0000050: N-Glycan antennae elongation

Addition of GalNAc to mucins to form the Tn antigen
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: GO_0004653
BFO_0000050: O-linked glycosylation of mucins
directly activates: C1GALT1 transfers galactose to the Tn antigen forming Core 1 glycoproteins (T antigens)
directly activates: Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein
directly activates: Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein
directly activates: Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein
directly activates: Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein
directly activates: Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein
directly activates: Catalysis1555
directly activates: Catalysis1557

C1GALT1 transfers galactose to the Tn antigen forming Core 1 glycoproteins (T antigens)
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: GO_0016263
BFO_0000050: O-linked glycosylation of mucins
directly activates: Addition of GlcNAc to the T antigen forms a Core 2 glycoprotein
directly activates: Catalysis1556

Addition of GlcNAc to the T antigen forms a Core 2 glycoprotein
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: GO_0003829
BFO_0000050: O-linked glycosylation of mucins

Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: GO_0008499
BFO_0000050: O-linked glycosylation of mucins
directly activates: Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein
directly activates: Catalysis1558

Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein
type: Restriction
  on property: enabled by
  some values from: GCNT3
type: Restriction
  on property: enabled by
  some values from: GCNT3
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: GO_0003829
BFO_0000050: O-linked glycosylation of mucins

Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein
type: GO_0003674
BFO_0000050: O-linked glycosylation of mucins

Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein
type: GO_0003674
BFO_0000050: O-linked glycosylation of mucins
directly activates: Addition of galactose to Core 6 glycoprotein
directly activates: Catalysis1559

Addition of galactose to Core 6 glycoprotein
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: GO_0008378
BFO_0000050: O-linked glycosylation of mucins

Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein
type: GO_0003674
BFO_0000050: O-linked glycosylation of mucins

Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein
type: GO_0003674
BFO_0000050: O-linked glycosylation of mucins

Sialyltransferase I can add sialic acid to the Tn antigen at the alpha 6 position
type: Restriction
  on property: enabled by
  some values from: SIAT1
type: Restriction
  on property: enabled by
  some values from: SIAT1
type: Restriction
  on property: enabled by
  some values from: SIAT1
type: Restriction
  on property: enabled by
  some values from: SIAT1
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: GO_0003835
BFO_0000050: Termination of O-glycan biosynthesis

Sialyltransferase I can add sialic acid to the T antigen at the alpha 6 position
type: Restriction
  on property: enabled by
  some values from: SIAT1
type: Restriction
  on property: enabled by
  some values from: SIAT1
type: Restriction
  on property: enabled by
  some values from: SIAT1
type: Restriction
  on property: enabled by
  some values from: SIAT1
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: GO_0003835
BFO_0000050: Termination of O-glycan biosynthesis

GalNAc alpha-2,6-sialyltransferase II can add a sialic acid to the T antigen at the alpha 6 position
type: Restriction
  on property: enabled by
  some values from: SIAT7B
type: Restriction
  on property: enabled by
  some values from: SIAT7B
type: Restriction
  on property: enabled by
  some values from: SIAT7B
type: Restriction
  on property: enabled by
  some values from: SIAT7B
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: GO_0008373
BFO_0000050: Termination of O-glycan biosynthesis

ST3GAL1-4 can add a sialic acid to the T antigen at the alpha 3 position
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: GO_0003836
BFO_0000050: Termination of O-glycan biosynthesis
directly activates: ST6GALNAC3/4 can add a sialic acid to the sialyl T antigen to form the disialyl T antigen
directly activates: Catalysis1564

ST6GALNAC3/4 can add a sialic acid to the sialyl T antigen to form the disialyl T antigen
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: GO_0047290
BFO_0000050: Termination of O-glycan biosynthesis

ER to Golgi Transport
type: GO_0008150
BFO_0000050: Transport to the Golgi and subsequent modification

COPII (Coat Protein 2) Mediated Vesicle Transport
type: GO_0008150
BFO_0000050: ER to Golgi Transport

Post-translational protein modification
type: GO_0008150

PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
type: GO_0008150
BFO_0000050: Post-translational protein modification

Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
type: GO_0008150
BFO_0000050: PTM: gamma carboxylation, hypusine formation and arylsulfatase activation

Gamma-carboxylation of protein precursors
type: GO_0008150
BFO_0000050: Gamma-carboxylation, transport, and amino-terminal cleavage of proteins

Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
type: GO_0008150
BFO_0000050: Gamma-carboxylation, transport, and amino-terminal cleavage of proteins

Removal of aminoterminal propeptides from gamma-carboxylated proteins
type: GO_0008150
BFO_0000050: Gamma-carboxylation, transport, and amino-terminal cleavage of proteins

Hypusine synthesis from eIF5A-lysine
type: GO_0008150
BFO_0000050: PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
label: Hypusinylation

The activation of arylsulfatases
type: GO_0008150
BFO_0000050: PTM: gamma carboxylation, hypusine formation and arylsulfatase activation

Post-translational modification: synthesis of GPI-anchored proteins
type: GO_0008150
BFO_0000050: Post-translational protein modification

Synthesis of dolichyl-phosphate mannose
type: GO_0008150
BFO_0000050: Post-translational modification: synthesis of GPI-anchored proteins
BFO_0000050: Synthesis of substrates in N-glycan biosythesis

Synthesis of glycosylphosphatidylinositol (GPI)
type: GO_0008150
BFO_0000050: Post-translational modification: synthesis of GPI-anchored proteins

Attachment of GPI anchor to uPAR
type: GO_0008150
BFO_0000050: Post-translational modification: synthesis of GPI-anchored proteins

Asparagine N-linked glycosylation
type: GO_0008150
BFO_0000050: Post-translational protein modification

Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
type: GO_0008150
BFO_0000050: Asparagine N-linked glycosylation

Synthesis of substrates in N-glycan biosythesis
type: GO_0008150
BFO_0000050: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein

Synthesis of Dolichyl-phosphate
type: GO_0008150
BFO_0000050: Synthesis of substrates in N-glycan biosythesis

Synthesis of UDP-N-acetyl-glucosamine
type: GO_0008150
BFO_0000050: Synthesis of substrates in N-glycan biosythesis

Synthesis of GDP-mannose
type: GO_0008150
BFO_0000050: Synthesis of substrates in N-glycan biosythesis

Synthesis of dolichyl-phosphate-glucose
type: GO_0008150
BFO_0000050: Synthesis of substrates in N-glycan biosythesis

N-glycan trimming in the ER and Calnexin/Calreticulin cycle
type: GO_0008150
BFO_0000050: Asparagine N-linked glycosylation

Calnexin/calreticulin cycle
type: GO_0008150
BFO_0000050: N-glycan trimming in the ER and Calnexin/Calreticulin cycle

ER Quality Control Compartment (ERQC)
type: GO_0008150
BFO_0000050: Calnexin/calreticulin cycle

Transport to the Golgi and subsequent modification
type: GO_0008150
BFO_0000050: Asparagine N-linked glycosylation

N-glycan trimming and elongation in the cis-Golgi
type: GO_0008150
BFO_0000050: Transport to the Golgi and subsequent modification

Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2
type: GO_0008150
BFO_0000050: N-glycan trimming and elongation in the cis-Golgi

N-glycan antennae elongation in the medial/trans-Golgi
type: GO_0008150
BFO_0000050: Transport to the Golgi and subsequent modification

Reactions specific to the hybrid N-glycan synthesis pathway
type: GO_0008150
BFO_0000050: N-glycan antennae elongation in the medial/trans-Golgi

Reactions specific to the complex N-glycan synthesis pathway
type: GO_0008150
BFO_0000050: N-glycan antennae elongation in the medial/trans-Golgi

N-Glycan antennae elongation
type: GO_0008150
BFO_0000050: N-glycan antennae elongation in the medial/trans-Golgi

O-linked glycosylation of mucins
type: GO_0008150
BFO_0000050: Post-translational protein modification

Termination of O-glycan biosynthesis
type: GO_0008150
BFO_0000050: O-linked glycosylation of mucins